TWO SIGMA INVESTMENTS, LP - ALPINE IMMUNE SCIENCES INC ownership

ALPINE IMMUNE SCIENCES INC's ticker is ALPN and the CUSIP is 02083G100. A total of 70 filers reported holding ALPINE IMMUNE SCIENCES INC in Q3 2022. The put-call ratio across all filers is - and the average weighting 0.8%.

Quarter-by-quarter ownership
TWO SIGMA INVESTMENTS, LP ownership history of ALPINE IMMUNE SCIENCES INC
ValueSharesWeighting
Q3 2023$2,182,244
+265.8%
190,589
+228.4%
0.01%
+500.0%
Q2 2023$596,528
+277.5%
58,028
+164.7%
0.00%0.0%
Q3 2022$158,000
-7.1%
21,924
+9.5%
0.00%0.0%
Q2 2022$170,000
-60.3%
20,030
-58.0%
0.00%0.0%
Q1 2022$428,000
-61.2%
47,708
-40.1%
0.00%
-50.0%
Q4 2021$1,104,000
+164.1%
79,682
+103.2%
0.00%
+100.0%
Q3 2021$418,000
+175.0%
39,218
+131.9%
0.00%
Q2 2021$152,000
-86.6%
16,914
-84.2%
0.00%
-100.0%
Q1 2021$1,138,000
-39.1%
107,381
-27.7%
0.00%
-40.0%
Q4 2020$1,870,000
+161.5%
148,443
+82.4%
0.01%
+66.7%
Q3 2020$715,000
-5.9%
81,365
+3.9%
0.00%
-25.0%
Q2 2020$760,00078,2990.00%
Other shareholders
ALPINE IMMUNE SCIENCES INC shareholders Q3 2022
NameSharesValueWeighting ↓
FRAZIER MANAGEMENT LLC 2,571,450$32,400,0002.50%
Omega Fund Management, LLC 1,284,900$16,190,0002.43%
Avidity Partners Management LP 1,248,000$15,725,0000.51%
Samsara BioCapital, LLC 399,190$5,030,0000.51%
EcoR1 Capital, LLC 741,290$9,340,0000.50%
DAFNA Capital Management LLC 113,202$1,426,0000.42%
TIGER MANAGEMENT L.L.C. 137,728$1,735,0000.39%
Orbimed Advisors 3,070,955$38,694,0000.34%
SPHERA FUNDS MANAGEMENT LTD. 198,260$2,498,0000.22%
Artal Group S.A. 593,030$7,472,0000.16%
View complete list of ALPINE IMMUNE SCIENCES INC shareholders