Orbimed Advisors Q3 2022 holdings

$5.39 Billion is the total value of Orbimed Advisors's 132 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 29.9% .

 Value Shares↓ Weighting
SVA  SINOVAC BIOTECH LTD$340,500
-2.6%
2,718,7350.0%6.32%
-0.2%
BMY BuyBRISTOL-MYERS SQUIBB CO$183,761
-5.2%
2,584,900
+2.6%
3.41%
-2.9%
HUM SellHUMANA INC$169,186
-1.2%
348,700
-4.6%
3.14%
+1.3%
SWTX SellSPRINGWORKS THERAPEUTICS INC$157,655
+6.2%
5,525,926
-8.3%
2.93%
+8.9%
BSX SellBOSTON SCIENTIFIC CORP$150,977
-7.3%
3,898,200
-10.8%
2.80%
-5.0%
BMRN BuyBIOMARIN PHARMACEUTICAL INC$145,576
+3.4%
1,717,310
+1.0%
2.70%
+5.9%
EWTX BuyEDGEWISE THERAPEUTICS INC$143,341
+27.9%
14,567,176
+3.4%
2.66%
+31.0%
UNH SellUNITEDHEALTH GROUP INC$134,947
-6.6%
267,200
-5.0%
2.50%
-4.3%
PFE SellPFIZER INC$113,732
-20.9%
2,599,000
-5.3%
2.11%
-19.0%
NewTHIRD HARMONIC BIO INC$109,6295,779,071
+100.0%
2.04%
VRTX SellVERTEX PHARMACEUTICALS INC$108,056
-1.0%
373,200
-3.6%
2.01%
+1.5%
TCDA  TRICIDA INC$107,744
+8.3%
10,280,9470.0%2.00%
+10.9%
ISRG BuyINTUITIVE SURGICAL INC$107,347
+3.4%
572,700
+10.7%
1.99%
+6.0%
ACET SellADICET BIO INC$105,898
-2.6%
7,447,140
-0.0%
1.97%
-0.2%
SGEN BuySEAGEN INC$104,347
-14.2%
762,600
+10.9%
1.94%
-12.1%
TMO BuyTHERMO FISHER SCIENTIFIC INC$102,554
+66.5%
202,200
+78.3%
1.90%
+70.6%
SRPT BuySAREPTA THERAPEUTICS INC$101,531
+6673.2%
918,500
+4492.5%
1.88%
+6881.5%
MRTX BuyMIRATI THERAPEUTICS INC$99,095
+35.4%
1,418,892
+30.1%
1.84%
+38.8%
 THESEUS PHARMACEUTICALS INC$98,842
+4.9%
17,041,6680.0%1.84%
+7.4%
NBIX BuyNEUROCRINE BIOSCIENCES INC$95,222
+15.0%
896,545
+5.5%
1.77%
+17.8%
ARGX BuyARGENX SEsponsored adr$95,218
+29.5%
269,700
+39.0%
1.77%
+32.7%
SYK SellSTRYKER CORPORATION$85,695
-2.3%
423,100
-4.1%
1.59%
+0.1%
ABBV SellABBVIE INC$80,526
-34.3%
600,000
-25.0%
1.50%
-32.7%
EW SellEDWARDS LIFESCIENCES CORP$79,845
-17.0%
966,300
-4.4%
1.48%
-14.9%
PMVP  PMV PHARMACEUTICALS INC$78,101
-16.5%
6,563,0770.0%1.45%
-14.5%
EVH BuyEVOLENT HEALTH INCcl a$71,670
+31.3%
1,994,717
+12.2%
1.33%
+34.5%
PRLD  PRELUDE THERAPEUTICS INC$66,362
+26.6%
10,039,6910.0%1.23%
+29.7%
NTRA SellNATERA INC$65,956
+12.0%
1,505,153
-9.4%
1.22%
+14.7%
KROS  KEROS THERAPEUTICS INC$63,180
+36.2%
1,679,4170.0%1.17%
+39.5%
CRNX  CRINETICS PHARMACEUTICALS IN$62,787
+5.3%
3,196,8760.0%1.17%
+8.0%
MRSN  MERSANA THERAPEUTICS INC$60,917
+46.3%
9,011,4370.0%1.13%
+50.0%
 PRELUDE THERAPEUTICS INCnonvoting$60,506
+3.8%
12,147,8770.0%1.12%
+6.3%
BIIB BuyBIOGEN INC$59,968
+163.5%
224,600
+101.3%
1.11%
+170.1%
SIBN  SI-BONE INC$58,805
+32.3%
3,368,0000.0%1.09%
+35.5%
VRNA  VERONA PHARMA PLCsponsored ads$58,201
+143.9%
5,694,8410.0%1.08%
+150.0%
ARQT SellARCUTIS BIOTHERAPEUTICS INC$53,508
-47.5%
2,800,000
-41.4%
0.99%
-46.2%
GH SellGUARDANT HEALTH INC$53,421
+28.1%
992,400
-4.0%
0.99%
+31.4%
XTNT BuyXTANT MED HLDGS INC$52,628
+38.9%
73,114,592
+0.2%
0.98%
+42.2%
ALNY NewALNYLAM PHARMACEUTICALS INC$50,140250,500
+100.0%
0.93%
CMPX  COMPASS THERAPEUTICS INC$50,071
-14.0%
21,960,8500.0%0.93%
-11.9%
BLU BuyBELLUS HEALTH INC NEW$48,971
+265.7%
4,634,900
+218.6%
0.91%
+274.1%
KNTE  KINNATE BIOPHARMA INC$48,321
-5.2%
4,043,6290.0%0.90%
-2.9%
SNDX SellSYNDAX PHARMACEUTICALS INC$48,216
+7.9%
2,006,500
-13.6%
0.90%
+10.5%
SBTX  SILVERBACK THERAPEUTICS INC$46,152
+24.5%
8,740,8870.0%0.86%
+27.5%
TERN BuyTERNS PHARMACEUTICALS INC$44,064
+368.7%
7,481,204
+97.3%
0.82%
+381.2%
ACRS BuyACLARIS THERAPEUTICS INC$43,418
+33.7%
2,758,434
+18.6%
0.81%
+37.1%
PGNY BuyPROGYNY INC$42,028
+131.5%
1,134,053
+81.4%
0.78%
+137.1%
ABCL  ABCELLERA BIOLOGICS INC$41,348
-7.1%
4,180,7680.0%0.77%
-4.8%
XENE SellXENON PHARMACEUTICALS INC$41,057
+1.5%
1,137,300
-14.4%
0.76%
+4.0%
RPTX  REPARE THERAPEUTICS INC$40,302
-13.3%
3,322,4880.0%0.75%
-11.2%
KDNY BuyCHINOOK THERAPEUTICS INC$39,896
+20.3%
2,029,300
+7.0%
0.74%
+23.3%
VECT  VECTIVBIO HLDG AG$38,841
+11.1%
6,473,5610.0%0.72%
+13.9%
JANX  JANUX THERAPEUTICS INC$38,405
+10.9%
2,836,3860.0%0.71%
+13.5%
IONS BuyIONIS PHARMACEUTICALS INC$34,008
+102.6%
768,900
+69.6%
0.63%
+107.6%
THC SellTENET HEALTHCARE CORP$33,181
-3.8%
643,300
-2.0%
0.62%
-1.4%
SCPH  SCPHARMACEUTICALS INC$31,277
+35.3%
4,797,1480.0%0.58%
+38.7%
TVTX BuyTRAVERE THERAPEUTICS INC$30,877
+65.0%
1,253,130
+62.3%
0.57%
+69.0%
RAPT BuyRAPT THERAPEUTICS INC$30,101
+90.4%
1,251,070
+44.4%
0.56%
+94.8%
QURE BuyUNIQURE NV$29,960
+83.7%
1,597,000
+82.5%
0.56%
+88.5%
ALPN  ALPINE IMMUNE SCIENCES INC$29,387
-15.4%
4,081,5920.0%0.55%
-13.2%
ALXO BuyALX ONCOLOGY HLDGS INC$27,475
+55.3%
2,871,000
+31.3%
0.51%
+59.4%
BHVN SellBIOHAVEN PHARMACTL HLDG CO L$25,815
-75.4%
170,769
-76.3%
0.48%
-74.8%
TELA  TELA BIO INC$25,795
+21.5%
3,027,5420.0%0.48%
+24.4%
GRCL  GRACELL BIOTECHNOLOGIES INCsponsored ads$25,389
-41.5%
7,884,8700.0%0.47%
-40.1%
ETNB  89BIO INC$21,185
+79.8%
3,658,8690.0%0.39%
+84.5%
IOVA SellIOVANCE BIOTHERAPEUTICS INC$19,231
-37.8%
2,007,458
-28.3%
0.36%
-36.2%
GHRS  GH RESEARCH PLCordinary shares$18,848
+16.4%
1,622,0600.0%0.35%
+19.5%
MGTX SellMEIRAGTX HLDGS PLC$17,729
-6.4%
2,108,143
-15.7%
0.33%
-4.1%
PCVX SellVAXCYTE INC$17,230
-47.7%
717,900
-52.6%
0.32%
-46.4%
DBTX  DECIBEL THERAPEUTICS INC$17,110
-17.8%
4,945,1920.0%0.32%
-15.6%
BuyINVIVYD INC$16,496
-0.5%
5,270,400
+4.2%
0.31%
+2.0%
KZR BuyKEZAR LIFE SCIENCES INC$15,254
+29.9%
1,771,700
+24.8%
0.28%
+32.9%
KALV BuyKALVISTA PHARMACEUTICALS INC$15,119
+728.9%
1,042,000
+462.0%
0.28%
+751.5%
New2SEVENTY BIO INC$15,1511,041,300
+100.0%
0.28%
NPCE  NEUROPACE INC$15,046
-24.2%
4,012,2810.0%0.28%
-22.5%
VSTM NewVERASTEM INC$14,62017,200,000
+100.0%
0.27%
SellRXSIGHT INC$14,434
-25.9%
1,202,833
-13.1%
0.27%
-24.1%
AVTE BuyAEROVATE THERAPEUTICS INC$13,181
+76.2%
795,000
+66.1%
0.24%
+80.1%
 BRIDGEBIO PHARMA INCnote 2.250% 2/0$12,509
+3.0%
30,000,0000.0%0.23%
+5.5%
 BRIDGEBIO PHARMA INCnote 2.500% 3/1$11,760
+30.7%
20,000,0000.0%0.22%
+33.7%
PASG  PASSAGE BIO INC$11,165
-47.0%
8,931,9990.0%0.21%
-45.8%
MIRM BuyMIRUM PHARMACEUTICALS INC$10,965
+101.6%
521,891
+86.7%
0.20%
+106.1%
IKNA  IKENA ONCOLOGY INC$10,415
-19.9%
2,933,9410.0%0.19%
-18.2%
NewCINCOR PHARMA INC$10,312314,202
+100.0%
0.19%
IMRA  IMARA INC$10,001
+86.9%
4,386,5680.0%0.19%
+91.8%
FUSN  FUSION PHARMACEUTICALS INC$9,707
+20.9%
3,224,7700.0%0.18%
+23.3%
GMTX SellGEMINI THERAPEUTICS INC$9,555
-3.0%
5,826,223
-0.0%
0.18%
-0.6%
MREO BuyMEREO BIOPHARMA GROUP PLCspon ads$9,132
+213.4%
10,605,522
+307.7%
0.17%
+220.8%
XFOR BuyX4 PHARMACEUTICALS INC$8,596
+548.3%
5,026,817
+265.9%
0.16%
+566.7%
CGEM SellCULLINAN ONCOLOGY INC$8,170
-5.0%
637,287
-5.0%
0.15%
-2.6%
RCUS NewARCUS BIOSCIENCES INC$7,926303,000
+100.0%
0.15%
SellVENTYX BIOSCIENCES INC$7,855
-50.2%
225,000
-82.5%
0.15%
-49.0%
GLTO  GALECTO INC$7,732
+9.3%
4,090,9370.0%0.14%
+12.5%
EYPT BuyEYEPOINT PHARMACEUTICALS INC$7,680
+355.8%
970,860
+353.5%
0.14%
+361.3%
NXTC  NEXTCURE INC$7,455
-41.5%
2,711,0130.0%0.14%
-40.3%
LUNG  PULMONX CORP$7,247
+13.2%
435,0000.0%0.14%
+16.4%
JNCE  JOUNCE THERAPEUTICS INC$6,854
-22.8%
2,928,9000.0%0.13%
-21.1%
ORIC  ORIC PHARMACEUTICALS INC$6,680
-28.6%
2,087,5680.0%0.12%
-26.6%
CMMB  CHEMOMAB THERAPEUTICS LTDsponsored ads$6,420
-32.7%
2,578,1740.0%0.12%
-31.2%
XBI SellSPDR SER TRs&p biotech$6,060
-27.0%
76,400
-31.7%
0.11%
-25.3%
PCVX NewVAXCYTE INCcall$6,000250,000
+100.0%
0.11%
SYBX  SYNLOGIC INC$5,728
-17.4%
6,029,9950.0%0.11%
-15.9%
CRVS  CORVUS PHARMACEUTICALS INC$5,683
-17.3%
6,943,6540.0%0.10%
-16.0%
CLXPF SellCYBIN INC$5,082
-13.7%
10,453,600
-0.7%
0.09%
-12.1%
LLY NewLILLY ELI & COcall$4,85015,000
+100.0%
0.09%
HRTX NewHERON THERAPEUTICS INC$4,7391,123,000
+100.0%
0.09%
SRRK SellSCHOLAR ROCK HLDG CORP$4,629
-21.7%
667,943
-38.0%
0.09%
-19.6%
GRAY  GRAYBUG VISION INC$3,915
-13.7%
4,163,3470.0%0.07%
-11.0%
APLT  APPLIED THERAPEUTICS INC$3,953
-1.9%
4,250,0000.0%0.07%0.0%
 VIGIL NEUROSCIENCE INC$3,742
+252.7%
411,1910.0%0.07%
+263.2%
SGEN SellSEAGEN INCcall$3,421
-61.3%
25,000
-50.0%
0.06%
-60.0%
ACHL SellACHILLES THERAPEUTICS PLCsponsored ads$3,307
-17.2%
1,463,251
-7.7%
0.06%
-15.3%
MGTA  MAGENTA THERAPEUTICS INC$3,174
+17.5%
2,250,9530.0%0.06%
+20.4%
AMRX NewAMNEAL PHARMACEUTICALS INC$3,1991,583,490
+100.0%
0.06%
BNR SellBURNING ROCK BIOTECH LTDsponsored ads$3,066
-24.2%
1,282,816
-7.7%
0.06%
-21.9%
HARP SellHARPOON THERAPEUTICS INC$2,935
-49.4%
3,025,908
-0.4%
0.05%
-48.6%
DYN NewDYNE THERAPEUTICS INC$2,799220,400
+100.0%
0.05%
GRPH  GRAPHITE BIO INC$2,689
+15.3%
848,4120.0%0.05%
+19.0%
TARA  PROTARA THERAPEUTICS INC$2,459
+1.0%
830,6410.0%0.05%
+4.5%
AFIB  ACUTUS MED INC$2,331
-21.4%
2,648,3860.0%0.04%
-20.4%
LOGC  LOGICBIO THERAPEUTICS INC$2,307
-22.2%
8,466,7830.0%0.04%
-20.4%
NewPYXIS ONCOLOGY INC$1,671848,252
+100.0%
0.03%
OCX SellONCOCYTE CORP$1,374
-46.2%
1,882,768
-33.7%
0.03%
-43.5%
OMIC  SINGULAR GENOMICS SYSTEMS IN$1,352
-34.5%
540,6970.0%0.02%
-32.4%
EPIX NewESSA PHARMA INC$1,166640,645
+100.0%
0.02%
BOLT NewBOLT BIOTHERAPEUTICS INC$1,141771,059
+100.0%
0.02%
AGLE  AEGLEA BIOTHERAPEUTICS INC$945
+4.1%
1,797,2210.0%0.02%
+12.5%
GLUE NewMONTE ROSA THERAPEUTICS INC$960117,455
+100.0%
0.02%
PHGE  BIOMX INC$957
-53.4%
2,813,4890.0%0.02%
-51.4%
VOR SellVOR BIOPHARMA INC$445
-89.3%
111,808
-86.6%
0.01%
-89.3%
LBPH  LONGBOARD PHARMACEUTICALS IN$422
+20.2%
113,5000.0%0.01%
+33.3%
APTX ExitAPTINYX INC$0-538,500
-100.0%
-0.01%
TALS ExitTALARIS THERAPEUTICS INC$0-235,995
-100.0%
-0.02%
ExitSONENDO INC$0-723,478
-100.0%
-0.02%
ExitSIGHT SCIENCES INC$0-200,000
-100.0%
-0.03%
GH ExitGUARDANT HEALTH INCcall$0-50,000
-100.0%
-0.04%
NMTR Exit9 METERS BIOPHARMA INC$0-8,505,729
-100.0%
-0.04%
ABCL ExitABCELLERA BIOLOGICS INCcall$0-250,000
-100.0%
-0.05%
CLDX ExitCELLDEX THERAPEUTICS INC NEW$0-112,700
-100.0%
-0.06%
CTMX ExitCYTOMX THERAPEUTICS INC$0-2,124,975
-100.0%
-0.07%
NVAX ExitNOVAVAX INCcall$0-75,000
-100.0%
-0.07%
ExitNANOSTRING TECHNOLOGIES INCnote 2.625% 3/0$0-6,000,000
-100.0%
-0.09%
IMCR ExitIMMUNOCORE HLDGS PLCads$0-131,100
-100.0%
-0.09%
NTRA ExitNATERA INCcall$0-150,000
-100.0%
-0.10%
MREO ExitMEREO BIOPHARMA GROUP PLCads$0-7,109,954
-100.0%
-0.14%
ExitERASCA INC$0-1,667,693
-100.0%
-0.17%
DHRPRB ExitDANAHER CORPORATION5% conv pfd b$0-8,039
-100.0%
-0.19%
MIST ExitMILESTONE PHARMACEUTICALS IN$0-1,817,521
-100.0%
-0.20%
VTGN ExitVISTAGEN THERAPEUTICS INC$0-13,421,283
-100.0%
-0.21%
SGFY ExitSIGNIFY HEALTH INC$0-900,000
-100.0%
-0.22%
TBPH ExitTHERAVANCE BIOPHARMA INC$0-1,370,250
-100.0%
-0.22%
ISEE ExitIVERIC BIO INC$0-1,361,400
-100.0%
-0.24%
REGN ExitREGENERON PHARMACEUTICALS$0-22,200
-100.0%
-0.24%
AMGN ExitAMGEN INC$0-57,100
-100.0%
-0.25%
GILD ExitGILEAD SCIENCES INC$0-287,600
-100.0%
-0.32%
GBT ExitGLOBAL BLOOD THERAPEUTICS IN$0-2,044,000
-100.0%
-1.18%
SRRA ExitSIERRA ONCOLOGY INC$0-1,964,770
-100.0%
-1.96%
TPTX ExitTURNING POINT THERAPEUTICS I$0-2,012,250
-100.0%
-2.74%
HZNP ExitHORIZON THERAPEUTICS PUB L$0-2,108,555
-100.0%
-3.05%

Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):

The following EDGAR filing(s) were analyzed to create this report:

The EDGAR filing(s) were signed by:

  • Sven H. Borho — Member

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EDGAR filings