$4.92 Billion is the total value of Avidity Partners Management LP's 98 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 54.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LLY | Buy | LILLY ELI & CO | $325,613,000 | +64.6% | 1,007,000 | +65.1% | 6.62% | +45.8% |
| New | SPDR SER TRcall | $321,404,000 | – | 4,052,000 | +100.0% | 6.53% | – | |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $203,140,000 | +18.8% | 970,200 | +33.7% | 4.13% | +5.2% |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $197,094,000 | +37.8% | 1,855,700 | +26.4% | 4.01% | +22.0% |
| ARVN | Buy | ARVINAS INC | $193,242,000 | +36.8% | 4,343,500 | +29.4% | 3.93% | +21.2% |
| ARGX | Sell | ARGENX SEsponsored adr | $173,630,000 | -20.0% | 491,800 | -14.1% | 3.53% | -29.1% |
| BIIB | Buy | BIOGEN INC | $160,200,000 | +78.3% | 600,000 | +36.2% | 3.26% | +57.9% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $148,476,000 | -33.6% | 512,800 | -35.3% | 3.02% | -41.2% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $134,253,000 | +28.0% | 5,586,900 | +2.5% | 2.73% | +13.4% |
| PRTA | New | PROTHENA CORP PLC | $119,259,000 | – | 1,967,000 | +100.0% | 2.42% | – |
| XBI | Sell | SPDR SER TRs&p biotech | $117,394,000 | -15.7% | 1,480,000 | -21.1% | 2.39% | -25.3% |
| ACHC | Buy | ACADIA HEALTHCARE COMPANY IN | $108,608,000 | +55.2% | 1,389,200 | +34.2% | 2.21% | +37.4% |
| AKRO | New | AKERO THERAPEUTICS INC | $106,304,000 | – | 3,122,000 | +100.0% | 2.16% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $104,814,000 | – | 948,200 | +100.0% | 2.13% | – |
| HUM | Sell | HUMANA INC | $102,860,000 | -46.7% | 212,000 | -48.6% | 2.09% | -52.8% |
| BSX | Buy | BOSTON SCIENTIFIC CORP | $98,320,000 | +4.5% | 2,538,600 | +0.5% | 2.00% | -7.5% |
| IMCR | Buy | IMMUNOCORE HLDGS PLCads | $97,593,000 | +93.8% | 2,079,100 | +54.0% | 1.98% | +71.6% |
| KRTX | Buy | KARUNA THERAPEUTICS INC | $97,125,000 | +275.3% | 431,800 | +111.1% | 1.98% | +232.5% |
| ANTM | Sell | ELEVANCE HEALTH INC | $94,300,000 | -55.7% | 207,600 | -52.9% | 1.92% | -60.8% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB L | $91,733,000 | -38.1% | 1,482,200 | -20.2% | 1.86% | -45.1% |
| ZNTL | Buy | ZENTALIS PHARMACEUTICALS INC | $91,472,000 | -9.2% | 4,223,100 | +17.8% | 1.86% | -19.6% |
| AVTR | Sell | AVANTOR INC | $88,643,000 | -57.2% | 4,522,600 | -32.0% | 1.80% | -62.1% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $84,957,000 | -3.7% | 2,051,600 | +38.7% | 1.73% | -14.8% |
| NTRA | Buy | NATERA INC | $76,028,000 | +56.7% | 1,735,000 | +26.7% | 1.55% | +38.8% |
| AXSM | New | AXSOME THERAPEUTICS INC | $68,652,000 | – | 1,538,600 | +100.0% | 1.40% | – |
| CTLT | Sell | CATALENT INC | $68,018,000 | -33.6% | 940,000 | -1.6% | 1.38% | -41.2% |
| ITCI | Buy | INTRA-CELLULAR THERAPIES INC | $65,258,000 | +47.4% | 1,402,500 | +80.9% | 1.33% | +30.6% |
| SGEN | Sell | SEAGEN INC | $60,958,000 | -37.4% | 445,500 | -19.0% | 1.24% | -44.5% |
| BIO | New | BIO RAD LABS INCcl a | $60,402,000 | – | 144,800 | +100.0% | 1.23% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $57,746,000 | – | 288,500 | +100.0% | 1.17% | – |
| APLS | Buy | APELLIS PHARMACEUTICALS INC | $57,645,000 | +492.9% | 844,000 | +292.6% | 1.17% | +425.6% |
| NTLA | Sell | INTELLIA THERAPEUTICS INC | $55,910,000 | -4.0% | 999,100 | -11.2% | 1.14% | -15.0% |
| IDYA | Buy | IDEAYA BIOSCIENCES INC | $55,434,000 | +35.1% | 3,715,400 | +25.0% | 1.13% | +19.6% |
| KZR | Buy | KEZAR LIFE SCIENCES INC | $46,618,000 | +39.2% | 5,414,400 | +33.7% | 0.95% | +23.3% |
| BLU | Buy | BELLUS HEALTH INC NEW | $45,901,000 | +16.5% | 4,346,700 | +1.9% | 0.93% | +3.1% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $45,774,000 | +77.3% | 2,321,200 | +75.2% | 0.93% | +57.0% |
| JAZZ | Buy | JAZZ PHARMACEUTICALS PLC | $42,426,000 | +338.6% | 318,300 | +413.4% | 0.86% | +288.7% |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $42,458,000 | +40.5% | 2,600,000 | +25.0% | 0.86% | +24.4% |
| ZLAB | New | ZAI LAB LTDadr | $42,203,000 | – | 1,234,000 | +100.0% | 0.86% | – |
| ARWR | Sell | ARROWHEAD PHARMACEUTICALS IN | $41,490,000 | -18.1% | 1,255,374 | -12.8% | 0.84% | -27.4% |
| PLRX | New | PLIANT THERAPEUTICS INC | $41,385,000 | – | 1,981,100 | +100.0% | 0.84% | – |
| DXCM | New | DEXCOM INC | $37,661,000 | – | 467,600 | +100.0% | 0.77% | – |
| SYK | New | STRYKER CORPORATION | $37,409,000 | – | 184,700 | +100.0% | 0.76% | – |
| VERV | New | VERVE THERAPEUTICS INC | $35,817,000 | – | 1,042,706 | +100.0% | 0.73% | – |
| ALT | Sell | ALTIMMUNE INC | $34,275,000 | -1.7% | 2,684,000 | -10.0% | 0.70% | -13.0% |
| CNC | New | CENTENE CORP DEL | $33,645,000 | – | 432,400 | +100.0% | 0.68% | – |
| Buy | CARIBOU BIOSCIENCES INC | $33,471,000 | +108.9% | 3,172,600 | +7.5% | 0.68% | +84.8% | |
| AZN | Sell | ASTRAZENECA PLCsponsored adr | $30,886,000 | -86.6% | 563,200 | -83.9% | 0.63% | -88.2% |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $23,519,000 | – | 1,798,100 | +100.0% | 0.48% | – |
| DCPH | Sell | DECIPHERA PHARMACEUTICALS IN | $22,048,000 | +39.7% | 1,191,800 | -0.7% | 0.45% | +23.8% |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $21,799,000 | – | 2,820,000 | +100.0% | 0.44% | – |
| PHAT | Sell | PHATHOM PHARMACEUTICALS INC | $21,127,000 | +30.4% | 1,906,800 | -0.7% | 0.43% | +15.6% |
| COGT | New | COGENT BIOSCIENCES INC | $20,257,000 | – | 1,357,700 | +100.0% | 0.41% | – |
| NKTX | NKARTA INC | $18,609,000 | +6.8% | 1,414,082 | 0.0% | 0.38% | -5.5% | |
| BGNE | New | BEIGENE LTDsponsored adr | $17,796,000 | – | 132,000 | +100.0% | 0.36% | – |
| SIBN | Sell | SI-BONE INC | $17,402,000 | +31.8% | 996,700 | -0.3% | 0.35% | +16.8% |
| GOSS | New | GOSSAMER BIO INC | $17,371,000 | – | 1,450,000 | +100.0% | 0.35% | – |
| CYTK | New | CYTOKINETICS INC | $16,231,000 | – | 335,000 | +100.0% | 0.33% | – |
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INC | $15,183,000 | – | 794,500 | +100.0% | 0.31% | – |
| PCVX | New | VAXCYTE INC | $15,089,000 | – | 628,700 | +100.0% | 0.31% | – |
| ATEC | ALPHATEC HLDGS INC | $14,989,000 | +33.6% | 1,715,000 | 0.0% | 0.30% | +18.7% | |
| KNTE | New | KINNATE BIOPHARMA INC | $14,491,000 | – | 1,212,611 | +100.0% | 0.30% | – |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $13,248,000 | -13.8% | 1,382,900 | -0.7% | 0.27% | -23.8% |
| Buy | AN2 THERAPEUTICS INC | $12,907,000 | +141.9% | 742,630 | +7.9% | 0.26% | +114.8% | |
| IPSC | Buy | CENTURY THERAPEUTICS INC | $12,893,000 | +77.4% | 1,303,600 | +50.7% | 0.26% | +56.9% |
| TMDX | New | TRANSMEDICS GROUP INC | $12,522,000 | – | 300,000 | +100.0% | 0.26% | – |
| SGMO | New | SANGAMO THERAPEUTICS INC | $11,568,000 | – | 2,360,800 | +100.0% | 0.24% | – |
| STOK | New | STOKE THERAPEUTICS INC | $11,442,000 | – | 891,100 | +100.0% | 0.23% | – |
| SPNE | SEASPINE HLDGS CORP | $11,417,000 | +0.5% | 2,010,000 | 0.0% | 0.23% | -11.1% | |
| NSTG | New | NANOSTRING TECHNOLOGIES INC | $8,916,000 | – | 698,200 | +100.0% | 0.18% | – |
| Sell | ERASCA INC | $7,664,000 | +38.3% | 982,500 | -1.3% | 0.16% | +22.8% | |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $7,190,000 | -15.4% | 998,600 | +0.0% | 0.15% | -25.1% |
| SGRY | New | SURGERY PARTNERS INC | $6,262,000 | – | 267,600 | +100.0% | 0.13% | – |
| New | SYROS PHARMACEUTICALS INC | $5,796,000 | – | 900,000 | +100.0% | 0.12% | – | |
| CMAX | CAREMAX INC | $5,355,000 | +95.3% | 755,329 | 0.0% | 0.11% | +73.0% | |
| MSAC | MEDICUS SCIENCES ACQUISITION | $5,148,000 | +1.2% | 520,000 | 0.0% | 0.10% | -10.3% | |
| GRPH | Buy | GRAPHITE BIO INC | $4,993,000 | +155.7% | 1,575,000 | +121.8% | 0.10% | +126.7% |
| BLSA | BCLS ACQUISITION CORP | $5,010,000 | +1.2% | 500,000 | 0.0% | 0.10% | -10.5% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $4,955,000 | +1.0% | 500,000 | 0.0% | 0.10% | -10.6% | |
| PANA | PANACEA ACQUISITION CORP II | $4,900,000 | +0.4% | 500,000 | 0.0% | 0.10% | -10.7% | |
| CMPX | COMPASS THERAPEUTICS INC | $4,560,000 | -14.0% | 2,000,000 | 0.0% | 0.09% | -23.8% | |
| EPIX | ESSA PHARMA INC | $4,477,000 | -42.2% | 2,460,000 | 0.0% | 0.09% | -48.9% | |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $3,960,000 | -0.6% | 400,000 | 0.0% | 0.08% | -11.0% | |
| CYT | Sell | CYTEIR THERAPEUTICS INC | $3,468,000 | -37.3% | 1,806,200 | -2.4% | 0.07% | -44.1% |
| Buy | TANGO THERAPEUTICS INC | $2,946,000 | -20.1% | 813,700 | +0.0% | 0.06% | -29.4% | |
| SCYX | Buy | SCYNEXIS INC | $2,737,000 | +53.3% | 1,140,600 | +18.9% | 0.06% | +36.6% |
| DNAB | SOCIAL CAP SUVRETTA HLDS CRP | $1,960,000 | +0.8% | 200,000 | 0.0% | 0.04% | -11.1% | |
| DNAD | SOCIAL CAP SUVRETTA HLDS CP | $1,964,000 | +1.1% | 200,000 | 0.0% | 0.04% | -11.1% | |
| ONCS | ONCOSEC MED INC | $1,437,000 | -34.2% | 2,945,000 | 0.0% | 0.03% | -42.0% | |
| HYPERFINE INC | $1,218,000 | -63.7% | 1,503,754 | 0.0% | 0.02% | -67.5% | ||
| ACIU | New | AC IMMUNE SA | $869,000 | – | 274,876 | +100.0% | 0.02% | – |
| SEMA4 HOLDINGS CORP | $834,000 | -30.3% | 950,000 | 0.0% | 0.02% | -37.0% | ||
| New | REUNION NEUROSCIENCE INC | $851,000 | – | 595,200 | +100.0% | 0.02% | – | |
| PHAS | Sell | PHASEBIO PHARMACEUTICALS INC | $768,000 | -70.9% | 4,361,365 | -1.0% | 0.02% | -73.8% |
| SCIENCE 37 HOLDINGS INC | $692,000 | -19.9% | 430,000 | 0.0% | 0.01% | -30.0% | ||
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $18,000 | -35.7% | 99,999 | 0.0% | 0.00% | -100.0% | |
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $1,000 | -90.0% | 57,770 | 0.0% | 0.00% | – | |
| DNAA | Exit | SOCIAL CAP SUVRETTA HLDS CRP | $0 | – | -200,000 | -100.0% | -0.04% | – |
| DNAC | Exit | SOCIAL CAP SUVRETTA HLD CRPI | $0 | – | -200,000 | -100.0% | -0.05% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -1,000,000 | -100.0% | -0.05% | – |
| Exit | FIELD TRIP HEALTH LTD | $0 | – | -2,976,000 | -100.0% | -0.06% | – | |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -430,117 | -100.0% | -0.10% | – |
| S | Exit | SENTINELONE INCcl a | $0 | – | -204,500 | -100.0% | -0.11% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -450,000 | -100.0% | -0.31% | – |
| NUVB | Exit | NUVATION BIO INC | $0 | – | -4,855,000 | -100.0% | -0.36% | – |
| VIR | Exit | VIR BIOTECHNOLOGY INC | $0 | – | -758,211 | -100.0% | -0.44% | – |
| ARKG | Exit | ARK ETF TRgenomic rev etf | $0 | – | -750,000 | -100.0% | -0.54% | – |
| LEGN | Exit | LEGEND BIOTECH CORPsponsored ads | $0 | – | -1,000,000 | -100.0% | -1.26% | – |
| ABBV | Exit | ABBVIE INC | $0 | – | -755,000 | -100.0% | -2.66% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -242,200 | -100.0% | -2.86% | – |
| MCK | Exit | MCKESSON CORP | $0 | – | -388,800 | -100.0% | -2.91% | – |
| JNJ | Exit | JOHNSON & JOHNSON | $0 | – | -900,200 | -100.0% | -3.67% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES INC | 15 | Q3 2023 | 4.6% |
| ARVINAS INC | 14 | Q3 2023 | 4.9% |
| ZENTALIS PHARMACEUTICALS INC | 14 | Q3 2023 | 4.8% |
| SYNDAX PHARMACEUTICALS INC | 14 | Q3 2023 | 3.2% |
| IDEAYA BIOSCIENCES INC | 13 | Q3 2023 | 2.5% |
| NATERA INC | 13 | Q3 2023 | 1.9% |
| ALPINE IMMUNE SCIENCES INC | 13 | Q3 2023 | 0.5% |
| ABBVIE INC | 12 | Q2 2023 | 9.7% |
| HORIZON THERAPEUTICS PUB LTD | 12 | Q3 2022 | 3.4% |
| AVANTOR INC | 11 | Q1 2023 | 6.0% |
View Avidity Partners Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adicet Bio, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ALPINE IMMUNE SCIENCES, INC. | February 14, 2023 | 1,888,887 | 4.0% |
| ESSA Pharma Inc. | February 14, 2023 | 1,855,400 | 4.2% |
| Gritstone bio, Inc. | February 14, 2023 | 2,859,971 | 3.3% |
| IVERIC bio, Inc. | February 14, 2023 | 838,407 | 0.6% |
| ONCOSEC MEDICAL IncSold out | February 14, 2023 | 0 | 0.0% |
| PhaseBio Pharmaceuticals Inc | February 14, 2023 | 2,040,000 | 4.1% |
| Phathom Pharmaceuticals, Inc. | February 14, 2023 | 1,900,000 | 4.6% |
| Viridian Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Anika Therapeutics, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
View Avidity Partners Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-09 |
| SC 13G | 2024-03-27 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
View Avidity Partners Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.