Orbimed Advisors Q3 2021 13F Holdings

Orbimed Advisors Q3 2021 holdings
TickerName Value Shares↓ Weighting
SWTX SPRINGWORKS THERAPEUTI...Reduce  $382,436
-23.2%
6,028,307
-0.3%
4.20%
-16.6%
PRLD PRELUDE THERAPEUTICS INC  $313,740
9.2%
10,039,6910.0%3.45%
18.6%
HZNP HORIZON THERAPEUTICS P...Reduce  $285,938
4.5%
2,610,355
-10.7%
3.14%
13.5%
MRK MERCK & CO INC  $280,341
-3.4%
3,732,4000.0%3.08%
4.9%
BMY BRISTOL-MYERS SQUIBB CO  $267,176
-11.4%
4,515,4000.0%2.94%
-3.8%
PRELUDE THERAPEUTICS INCnonvoting  $255,945
2.4%
11,895,6520.0%2.81%
11.3%
BSX BOSTON SCIENTIFIC CORPReduce  $253,120
-14.5%
5,833,600
-15.7%
2.78%
-7.0%
MRTX MIRATI THERAPEUTICS INCAdd  $242,933
19.0%
1,373,200
8.6%
2.67%
29.3%
EWTX EDGEWISE THERAPEUTICS INC  $231,482
-22.2%
13,944,6800.0%2.54%
-15.4%
ADAGIO THERAPEUTICS INCNew  $227,3995,383,5002.50%
PMVP PMV PHARMACEUTICALS INC  $218,447
-12.8%
7,330,4230.0%2.40%
-5.2%
NTRA NATERA INCReduce  $175,273
-25.0%
1,572,800
-23.6%
1.93%
-18.5%
IOVA IOVANCE BIOTHERAPEUTIC...  $163,868
-5.2%
6,645,1000.0%1.80%
3.0%
VRTX VERTEX PHARMACEUTICALS...Reduce  $159,152
-25.9%
877,400
-17.6%
1.75%
-19.5%
TPTX TURNING POINT THERAPEU...  $156,863
-14.9%
2,361,3270.0%1.72%
-7.5%
GH GUARDANT HEALTH INC  $153,437
0.7%
1,227,4000.0%1.69%
9.3%
ABBV ABBVIE INCAdd  $153,240
16.5%
1,420,600
21.7%
1.68%
26.6%
UNH UNITEDHEALTH GROUP INC  $152,271
-2.4%
389,7000.0%1.67%
6.0%
ARQT ARCUTIS BIOTHERAPEUTIC...  $145,104
-12.5%
6,073,8500.0%1.60%
-4.9%
ISRG INTUITIVE SURGICAL INC  $138,783
8.1%
139,6000.0%1.52%
17.4%
XBI SPDR SER TRs&p biotechAdd  $133,969
5.7%
1,065,700
13.9%
1.47%
14.9%
HUM HUMANA INC  $130,365
-12.1%
335,0000.0%1.43%
-4.5%
EW EDWARDS LIFESCIENCES CORP  $127,520
9.3%
1,126,4000.0%1.40%
18.7%
DXCM DEXCOM INCReduce  $124,684
-1.8%
228,000
-23.3%
1.37%
6.7%
NBIX NEUROCRINE BIOSCIENCES...Reduce  $114,326
-4.6%
1,192,015
-3.2%
1.26%
3.6%
GRCL GRACELL BIOTECHNOLOGIE...sponsored ads  $109,363
6.7%
7,884,8700.0%1.20%
15.9%
ZBH ZIMMER BIOMET HOLDINGS...New  $96,715660,8001.06%
SYK STRYKER CORPORATION  $88,979
1.5%
337,4000.0%0.98%
10.4%
KNTE KINNATE BIOPHARMA INC  $88,579
-1.1%
3,847,9290.0%0.97%
7.4%
SBTX SILVERBACK THERAPEUTIC...  $87,234
-67.7%
8,740,8870.0%0.96%
-64.9%
RPTX REPARE THERAPEUTICS INCReduce  $87,182
-18.4%
3,322,488
-3.0%
0.96%
-11.4%
IMGN IMMUNOGEN INCAdd  $84,471
-0.9%
14,897,914
15.2%
0.93%
7.7%
ABCL ABCELLERA BIOLOGICS INCReduce  $83,783
-38.8%
4,180,768
-32.8%
0.92%
-33.5%
XTNT XTANT MED HLDGS INC  $80,890
-31.9%
72,873,4940.0%0.89%
-26.0%
SVA SINOVAC BIOTECH LTD  $78,400
2.1%
2,839,5000.0%0.86%
10.9%
ANTM ANTHEM INCReduce  $77,207
-39.8%
207,100
-38.3%
0.85%
-34.6%
JANX JANUX THERAPEUTICS INC  $74,978
-13.3%
3,466,3860.0%0.82%
-5.8%
DCPH DECIPHERA PHARMACEUTIC...Reduce  $74,183
-38.5%
2,183,143
-33.8%
0.82%
-33.3%
ETNB 89BIO INC  $73,060
4.8%
3,729,4420.0%0.80%
13.9%
PGNY PROGYNY INCReduce  $71,123
-11.7%
1,270,045
-7.0%
0.78%
-4.0%
PASG PASSAGE BIO INC  $69,350
-24.8%
6,962,8990.0%0.76%
-18.2%
CRSP CRISPR THERAPEUTICS AGnamen aktAdd  $68,580
-18.4%
612,700
18.1%
0.75%
-11.3%
KROS KEROS THERAPEUTICS INC  $66,438
-6.9%
1,679,4170.0%0.73%
1.2%
BIIB BIOGEN INCAdd  $66,276
184.0%
234,200
247.5%
0.73%
208.5%
NPCE NEUROPACE INC  $63,595
-33.4%
4,012,2810.0%0.70%
-27.6%
TMO THERMO FISHER SCIENTIF...  $63,018
13.3%
110,3000.0%0.69%
23.1%
CRNX CRINETICS PHARMACEUTIC...  $63,084
11.7%
2,996,8760.0%0.69%
21.4%
ACET ADICET BIO INC  $56,706
-23.8%
7,232,8560.0%0.62%
-17.3%
OSH OAK STR HEALTH INC  $56,493
-27.4%
1,328,3000.0%0.62%
-21.1%
MGTX MEIRAGTX HLDGS PLC  $54,077
-15.0%
4,102,9250.0%0.59%
-7.6%
ORIC ORIC PHARMACEUTICALS INC  $48,879
18.2%
2,337,5740.0%0.54%
28.5%
SIBN SI-BONE INCAdd  $48,152
17.2%
2,248,000
72.2%
0.53%
27.5%
HCA HCA HEALTHCARE INCNew  $47,039193,8000.52%
ERASCA INCNew  $45,9912,167,3410.50%
SEM SELECT MED HLDGS CORP  $45,976
-14.4%
1,271,1000.0%0.50%
-7.0%
SGEN SEAGEN INCNew  $45,506268,0000.50%
TCDA TRICIDA INC  $44,610
7.4%
9,614,2800.0%0.49%
16.7%
TBPH THERAVANCE BIOPHARMA INCAdd  $43,624
-34.2%
5,895,159
29.2%
0.48%
-28.5%
ALPN ALPINE IMMUNE SCIENCES...Add  $43,551
57.6%
4,081,592
32.9%
0.48%
71.1%
MREO MEREO BIOPHARMA GROUP PLCadsNew  $41,78117,264,7640.46%
TELA TELA BIO INC  $41,356
-15.2%
3,027,5420.0%0.45%
-7.9%
CYTEK BIOSCIENCES INCNew  $41,1741,923,1390.45%
VECT VECTIVBIO HLDG AG  $39,578
-33.7%
5,123,3040.0%0.44%
-28.0%
TERN TERNS PHARMACEUTICALS INC  $39,504
-15.0%
3,791,2040.0%0.43%
-7.7%
LOGC LOGICBIO THERAPEUTICS INC  $38,778
3.2%
8,466,7830.0%0.43%
12.1%
DBTX DECIBEL THERAPEUTICS INC  $38,127
-10.4%
4,945,1920.0%0.42%
-2.6%
GLPG GALAPAGOS NVspon adrAdd  $38,061
139.3%
723,457
213.3%
0.42%
159.6%
APLT APPLIED THERAPEUTICS INC  $37,473
-20.1%
2,257,3870.0%0.41%
-13.1%
IKNA IKENA ONCOLOGY INC  $37,026
-10.1%
2,933,9410.0%0.41%
-2.4%
VTGN VISTAGEN THERAPEUTICS INCReduce  $35,371
-22.4%
12,909,283
-10.8%
0.39%
-15.6%
CRVS CORVUS PHARMACEUTICALS...Reduce  $33,607
56.3%
6,943,654
-13.8%
0.37%
70.0%
BNR BURNING ROCK BIOTECH LTDsponsored ads  $33,189
-39.3%
1,856,2010.0%0.36%
-34.0%
SRRA SIERRA ONCOLOGY INC  $32,383
12.6%
1,477,3200.0%0.36%
22.3%
AGLE AEGLEA BIOTHERAPEUTICS...  $31,923
14.2%
4,015,5240.0%0.35%
24.0%
SCPH SCPHARMACEUTICALS INC  $31,901
8.8%
4,797,1480.0%0.35%
18.6%
GHRS GH RESEARCH PLCordinary shares  $31,516
1.5%
1,428,6660.0%0.35%
10.2%
VRNA VERONA PHARMA PLCsponsored ads  $31,208
-16.2%
5,694,8410.0%0.34%
-9.0%
FLDM FLUIDIGM CORP DELReduce  $30,311
5.6%
4,599,571
-1.3%
0.33%
14.8%
CLXPF CYBIN INCNew  $29,46313,447,1210.32%
CMMB CHEMOMAB THERAPEUTICS LTDsponsored ads  $28,566
-41.7%
2,578,1740.0%0.31%
-36.7%
CRIS CURIS INC  $27,573
-3.0%
3,521,4000.0%0.30%
5.6%
MRSN MERSANA THERAPEUTICS INCAdd  $27,242
-28.4%
2,888,847
3.2%
0.30%
-22.3%
NSTG NANOSTRING TECHNOLOGIE...  $26,694
-25.9%
556,0000.0%0.29%
-19.5%
PCVX VAXCYTE INCAdd  $26,249
23.3%
1,034,665
9.4%
0.29%
34.0%
CGEM CULLINAN ONCOLOGY INC  $25,868
-12.4%
1,146,1450.0%0.28%
-5.0%
FUSN FUSION PHARMACEUTICALS...  $25,540
-2.0%
3,224,7700.0%0.28%
6.4%
GRPH GRAPHITE BIO INCAdd  $23,764
-30.1%
1,449,904
31.1%
0.26%
-24.1%
GMTX GEMINI THERAPEUTICS INC  $23,538
-37.6%
5,826,2240.0%0.26%
-32.0%
AFIB ACUTUS MED INCReduce  $23,412
-74.8%
2,648,386
-51.7%
0.26%
-72.7%
CLDX CELLDEX THERAPEUTICS I...New  $22,368414,3000.25%
OMIC SINGULAR GENOMICS SYST...  $22,363
-59.3%
1,998,5210.0%0.25%
-55.7%
OLMA OLEMA PHARMACEUTICALS INC  $22,263
-1.5%
807,7920.0%0.24%
7.0%
CTIC CTI BIOPHARMA CORP  $22,186
18.0%
7,520,6000.0%0.24%
28.4%
THC TENET HEALTHCARE CORPNew  $20,709311,7000.23%
HARP HARPOON THERAPEUTICS INC  $20,629
-43.0%
2,611,3080.0%0.23%
-38.0%
GILD GILEAD SCIENCES INC  $20,089
1.4%
287,6000.0%0.22%
10.5%
JNCE JOUNCE THERAPEUTICS INCAdd  $19,731
35.1%
2,655,600
23.7%
0.22%
46.6%
QURE UNIQURE NVAdd  $18,744
29.2%
585,574
24.3%
0.21%
40.1%
VRCA VERRICA PHARMACEUTICAL...  $18,497
10.6%
1,479,7330.0%0.20%
20.1%
SYBX SYNLOGIC INCAdd  $18,391
27.9%
6,029,995
63.1%
0.20%
39.3%
NXTC NEXTCURE INC  $18,272
-16.1%
2,711,0130.0%0.20%
-8.6%
KDNY CHINOOK THERAPEUTICS INCAdd  $18,127
-3.7%
1,420,637
6.5%
0.20%
4.7%
IMRA IMARA INCAdd  $17,897
-16.7%
4,386,568
61.3%
0.20%
-9.2%
HUMACYTE INCNew  $17,4151,500,0000.19%
NRIX NURIX THERAPEUTICS INCAdd  $17,334
117.8%
578,583
92.9%
0.19%
134.6%
FLXN FLEXION THERAPEUTICS INC  $16,893
-25.9%
2,769,3830.0%0.19%
-19.5%
RXSIGHT INCNew  $15,8381,250,0000.17%
LUNG PULMONX CORPAdd  $15,651
183.8%
435,000
248.0%
0.17%
207.1%
BLU BELLUS HEALTH INC NEWReduce  $14,960
21.9%
2,454,800
-37.9%
0.16%
32.3%
MIST MILESTONE PHARMACEUTIC...  $14,754
3.8%
2,583,8210.0%0.16%
12.5%
GLTO GALECTO INC  $14,686
-29.1%
4,090,9370.0%0.16%
-23.0%
DICE THERAPEUTICS INCNew  $14,410440,0000.16%
GRAY GRAYBUG VISION INC  $13,822
-38.9%
4,163,3470.0%0.15%
-33.6%
MGTA MAGENTA THERAPEUTICS INCReduce  $13,781
-30.7%
1,892,953
-6.9%
0.15%
-24.9%
CVRX CVRX INCAdd  $13,230
18.1%
799,861
100.0%
0.14%
28.3%
VOR VOR BIOPHARMA INC  $13,067
-15.9%
833,3330.0%0.14%
-8.3%
ACHL ACHILLES THERAPEUTICS PLCsponsored ads  $12,346
-20.4%
1,584,8450.0%0.14%
-13.4%
AMGN AMGEN INC  $12,142
-12.8%
57,1000.0%0.13%
-5.7%
ACRS ACLARIS THERAPEUTICS INCAdd  $11,732
84.6%
651,783
80.1%
0.13%
101.6%
AVTE AEROVATE THERAPEUTICS INC  $11,239
-8.1%
535,7140.0%0.12%0.0%
CBIO CATALYST BIOSCIENCES INCAdd  $11,145
21.5%
2,711,600
28.0%
0.12%
31.2%
NMTR 9 METERS BIOPHARMA INC  $11,136
18.2%
8,565,9740.0%0.12%
28.4%
ALXO ALX ONCOLOGY HLDGS INC  $11,079
35.1%
150,0000.0%0.12%
47.0%
EVH EVOLENT HEALTH INCcl aNew  $10,695345,0000.12%
IPSC CENTURY THERAPEUTICS INC  $10,241
-14.3%
407,0470.0%0.11%
-6.6%
OCX ONCOCYTE CORPAdd  $10,167
-15.7%
2,856,000
36.0%
0.11%
-8.2%
MAPS WM TECHNOLOGY INC  $10,156
-18.8%
700,4000.0%0.11%
-11.8%
AADI BIOSCIENCES INCNew  $10,170346,2620.11%
KZR KEZAR LIFE SCIENCES INCAdd  $9,936
228.4%
1,150,000
106.4%
0.11%
251.6%
NVAX NOVAVAX INCReduce  $9,449
-77.8%
45,580
-77.2%
0.10%
-75.8%
CTMX CYTOMX THERAPEUTICS INCAdd  $9,273
-3.2%
1,821,868
20.4%
0.10%
5.2%
KALA KALA PHARMACEUTICALS INCReduce  $9,010
-68.9%
3,438,998
-37.1%
0.10%
-66.2%
NAUT NAUTILUS BIOTECHNOLOGY...Reduce  $8,920
-42.9%
1,452,774
-6.1%
0.10%
-38.0%
PHGE BIOMX INCAdd  $8,609
-31.8%
2,813,489
21.6%
0.10%
-25.8%
BMRN BIOMARIN PHARMACEUTICA...New  $8,571110,9000.09%
CNVY CONVEY HLDG PARENT INC  $8,400
-26.2%
1,000,0000.0%0.09%
-20.0%
REGN REGENERON PHARMACEUTICALSNew  $8,20613,5600.09%
SYRS SYROS PHARMACEUTICALS INC  $8,214
-18.0%
1,837,5000.0%0.09%
-10.9%
IMAB I MABsponsored ads  $8,055
-13.7%
111,1200.0%0.09%
-5.3%
NANOSTRING TECHNOLOGIE...note 2.625% 3/0  $7,855
-19.1%
6,000,0000.0%0.09%
-12.2%
EVH EVOLENT HEAL... EVHcallcl aNew  $7,750250,0000.08%
XENE XENON PHARMACEUTICALS INCReduce  $7,289
-70.7%
477,000
-64.2%
0.08%
-68.1%
XFOR X4 PHARMACEUTICALS INC  $7,268
-18.6%
1,373,8490.0%0.08%
-11.1%
NTLA INTELLIA THERAPEUTICS INCNew  $7,13753,2000.08%
FIELD TRIP HEALTH LTDNew  $6,9961,538,4700.08%
SURF SURFACE ONCOLOGY INCNew  $6,886909,6660.08%
OWLET INCNew  $6,7081,200,0000.07%
SRPT SAREPTA THERAPEUTICS INC  $5,983
18.9%
64,7000.0%0.07%
29.4%
RXDX PROMETHEUS BIOSCIENCES...  $5,928
-3.5%
250,0000.0%0.06%
4.8%
APTOSE BIOSCIENCES INCReduce  $5,656
-78.8%
2,594,348
-67.7%
0.06%
-77.0%
NBTX NANOBIOTIX SAsponsored ads  $5,680
-17.6%
500,0000.0%0.06%
-11.4%
PROCEPT BIOROBOTICS CORPNew  $5,150135,0000.06%
HSAQ HEALTH SCIENCES ACQ CO...  $4,945
-3.0%
500,0000.0%0.05%
3.8%
SIGHT SCIENCES INCNew  $4,540200,0000.05%
RGEN REPLIGEN CORPNew  $4,25514,7240.05%
LABP LANDOS BIOPHARMA INCReduce  $4,135
-47.4%
283,217
-58.4%
0.04%
-43.8%
ADAG ADAGENE INCads  $3,950
5.9%
275,0000.0%0.04%
13.2%
CABA CABALETTA BIO INCNew  $3,679302,5090.04%
SNDX SYNDAX PHARMACEUTICALS...New  $3,642190,6000.04%
ASLN ASLAN PHARMACEUTICALS LTDadsReduce  $3,507
-57.8%
1,970,000
-21.8%
0.04%
-53.6%
TALS TALARIS THERAPEUTICS INC  $3,353
-7.7%
247,2400.0%0.04%0.0%
INZY INOZYME PHARMA INCAdd  $3,407
5.9%
294,000
55.8%
0.04%
12.1%
TARA PROTARA THERAPEUTICS INC  $3,114
-29.0%
450,0000.0%0.03%
-22.7%
IFRX INFLARX NV  $2,756
-12.8%
1,064,1180.0%0.03%
-6.2%
SBBP STRONGBRIDGE BIOPHARMA...Reduce  $1,621
-68.7%
794,675
-54.5%
0.02%
-65.4%
KZR KEZAR LIFE S... KZRcallNew  $980113,4000.01%
LBPH LONGBOARD PHARMACEUTIC...  $1,004
-3.0%
113,5000.0%0.01%
10.0%
MAPSW WM TECHNOLOG... MAPSWcall*w exp 06/16/202  $649
-32.0%
150,2000.0%0.01%
-30.0%
PHAS PHASEBIO PHARMACEUTICA...New  $551177,1130.01%
APTX APTINYX INCNew  $359153,2850.00%
AZN ASTRAZENECA PLC AZNcallsponsored adrNew  $3125,2000.00%
OWLET INC call*w exp 09/14/202New  $207220,7040.00%
PPBT PURPLE BIOTECH LTDsponsored adsSold out  $0-17,712-0.00%
CVAC CUREVAC N V CVACcallSold out  $0-30,000-0.02%
OGN ORGANON & COSold out  $0-166,939-0.05%
VERV VERVE THERAPEUTICS INCSold out  $0-100,000-0.06%
OTIC OTONOMY INCSold out  $0-3,250,000-0.07%
DYN DYNE THERAPEUTICS INCSold out  $0-350,000-0.07%
GLUE MONTE ROSA THERAPEUTIC...Sold out  $0-350,000-0.08%
STRO SUTRO BIOPHARMA INCSold out  $0-433,700-0.08%
ARPO AERPIO PHARMACEUTICALS...Sold out  $0-5,193,946-0.09%
CVAC CUREVAC N V CVACputSold out  $0-140,000-0.10%
BSX BOSTON SCIEN... BSXcallSold out  $0-250,000-0.11%
ALEC ALECTOR INCSold out  $0-611,478-0.13%
RLAY RELAY THERAPEUTICS INCSold out  $0-350,000-0.13%
ALXN ALEXION PHARMACEUTICAL...Sold out  $0-150,900-0.28%
ARCT ARCTURUS THERAPEUTICS ...Sold out  $0-848,503-0.29%
TRILLIUM THERAPEUTICS INCSold out  $0-3,322,300-0.33%
MREO MEREO BIOPHARMA GROUP PLCadsSold out  $0-17,264,764-0.55%
ASND ASCENDIS PHARMA A/Ssponsored adrSold out  $0-447,859-0.60%
AUPH AURINIA PHARMACEUTICAL...Sold out  $0-6,069,032-0.80%
  • Orbimed Advisors Q3 2021 Portfolio
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  • Quarter
    Q3 2021
  • Total value
    $9.1 Billion
  • Holdings
    173
  • Turnover
    32.1%
  • EDGAR