Orbimed Advisors Q2 2021 13F Holdings

Orbimed Advisors Q2 2021 holdings
TickerName Value Shares↓ Weighting
SWTX SPRINGWORKS THERAPEUTI...Reduce  $498,108
9.4%
6,044,266
-2.3%
5.04%
18.4%
BMY BRISTOL-MYERS SQUIBB CO  $301,719
5.8%
4,515,4000.0%3.05%
14.5%
EWTX EDGEWISE THERAPEUTICS INC  $297,440
-34.4%
13,944,6800.0%3.01%
-29.0%
BSX BOSTON SCIENTIFIC CORP  $295,925
10.6%
6,920,6000.0%2.99%
19.7%
MRK MERCK & CO INC  $290,269
0.9%
3,732,4000.0%2.94%
9.1%
PRLD PRELUDE THERAPEUTICS INC  $287,436
-33.9%
10,039,6910.0%2.91%
-28.5%
HZNP HORIZON THERAPEUTICS P...Reduce  $273,631
-5.5%
2,922,155
-7.1%
2.77%
2.3%
SBTX SILVERBACK THERAPEUTIC...  $270,006
-29.2%
8,740,8870.0%2.73%
-23.4%
PMVP PMV PHARMACEUTICALS INC  $250,407
3.9%
7,330,4230.0%2.53%
12.4%
PRELUDE THERAPEUTICS INCnonvoting  $249,889
-40.7%
11,895,6520.0%2.53%
-35.9%
NTRA NATERA INCReduce  $233,622
4.8%
2,057,800
-6.3%
2.36%
13.3%
VRTX VERTEX PHARMACEUTICALS...Reduce  $214,817
-12.0%
1,065,400
-6.2%
2.17%
-4.8%
MRTX MIRATI THERAPEUTICS INCAdd  $204,206
-2.4%
1,264,200
3.5%
2.06%
5.6%
TPTX TURNING POINT THERAPEU...  $184,231
-17.5%
2,361,3270.0%1.86%
-10.8%
IOVA IOVANCE BIOTHERAPEUTIC...  $172,906
-17.8%
6,645,1000.0%1.75%
-11.1%
ARQT ARCUTIS BIOTHERAPEUTIC...  $165,755
-5.7%
6,073,8500.0%1.68%
2.1%
UNH UNITEDHEALTH GROUP INCReduce  $156,051
4.1%
389,700
-3.3%
1.58%
12.6%
GH GUARDANT HEALTH INCAdd  $152,431
2.2%
1,227,400
25.6%
1.54%
10.5%
HUM HUMANA INCAdd  $148,311
12.8%
335,000
6.8%
1.50%
22.1%
ABCL ABCELLERA BIOLOGICS INCReduce  $136,906
-50.8%
6,223,019
-24.1%
1.38%
-46.8%
ABBV ABBVIE INCReduce  $131,507
0.2%
1,167,500
-3.8%
1.33%
8.3%
ISRG INTUITIVE SURGICAL INC  $128,382
24.5%
139,6000.0%1.30%
34.6%
ANTM ANTHEM INCAdd  $128,170
24.6%
335,700
17.1%
1.30%
34.7%
DXCM DEXCOM INC  $126,990
18.8%
297,4000.0%1.28%
28.5%
XBI SPDR SER TRs&p biotechNew  $126,694935,7001.28%
DCPH DECIPHERA PHARMACEUTIC...Add  $120,714
95.0%
3,297,301
138.8%
1.22%
110.9%
NBIX NEUROCRINE BIOSCIENCES...Reduce  $119,812
-5.4%
1,231,115
-5.4%
1.21%
2.4%
XTNT XTANT MED HLDGS INC  $118,784
-30.9%
72,873,4940.0%1.20%
-25.3%
EW EDWARDS LIFESCIENCES CORP  $116,661
23.8%
1,126,4000.0%1.18%
33.9%
RPTX REPARE THERAPEUTICS INC  $106,833
1.6%
3,426,3250.0%1.08%
10.0%
GRCL GRACELL BIOTECHNOLOGIE...sponsored ads  $102,503
-15.6%
7,884,8700.0%1.04%
-8.6%
NPCE NEUROPACE INCNew  $95,4524,012,2810.96%
AFIB ACUTUS MED INC  $93,016
27.0%
5,477,9580.0%0.94%
37.4%
PASG PASSAGE BIO INC  $92,189
-24.3%
6,962,8990.0%0.93%
-18.1%
KNTE KINNATE BIOPHARMA INC  $89,580
-25.3%
3,847,9290.0%0.91%
-19.2%
SYK STRYKER CORPORATION  $87,633
6.6%
337,4000.0%0.89%
15.4%
JANX JANUX THERAPEUTICS INCNew  $86,4863,466,3860.88%
IMGN IMMUNOGEN INCAdd  $85,252
15.3%
12,936,622
41.7%
0.86%
24.6%
CRSP CRISPR THERAPEUTICS AGnamen aktReduce  $84,021
24.8%
519,000
-6.1%
0.85%
35.1%
PGNY PROGYNY INCReduce  $80,561
-6.0%
1,365,445
-29.1%
0.82%
1.7%
AUPH AURINIA PHARMACEUTICAL...  $78,655
-0.2%
6,069,0320.0%0.80%
8.0%
OSH OAK STR HEALTH INCAdd  $77,799
48.2%
1,328,300
37.4%
0.79%
60.3%
SVA SINOVAC BIOTECH LTD  $76,800
6.7%
2,839,5000.0%0.78%
15.5%
ACET ADICET BIO INC  $74,426
-21.3%
7,232,8560.0%0.75%
-14.9%
KROS KEROS THERAPEUTICS INC  $71,325
-31.0%
1,679,4170.0%0.72%
-25.4%
ETNB 89BIO INC  $69,741
-21.0%
3,729,4420.0%0.70%
-14.6%
TBPH THERAVANCE BIOPHARMA INCReduce  $66,270
-47.8%
4,564,045
-26.6%
0.67%
-43.6%
MGTX MEIRAGTX HLDGS PLC  $63,595
7.4%
4,102,9250.0%0.64%
16.1%
VECT VECTIVBIO HLDG AGNew  $59,7385,123,3040.60%
ASND ASCENDIS PHARMA A/Ssponsored adrReduce  $58,916
-9.5%
447,859
-11.3%
0.60%
-2.1%
CRNX CRINETICS PHARMACEUTIC...Add  $56,491
34.3%
2,996,876
8.8%
0.57%
45.3%
TMO THERMO FISHER SCIENTIF...  $55,643
10.5%
110,3000.0%0.56%
19.5%
OMIC SINGULAR GENOMICS SYST...New  $54,9191,998,5210.56%
MREO MEREO BIOPHARMA GROUP PLCadsAdd  $54,730
-5.9%
17,264,764
0.0%
0.55%
1.8%
BNR BURNING ROCK BIOTECH LTDsponsored adsReduce  $54,684
7.0%
1,856,201
-2.2%
0.55%
15.7%
SEM SELECT MED HLDGS CORPNew  $53,7171,271,1000.54%
CMMB CHEMOMAB THERAPEUTICS LTDsponsored ads  $49,037
-33.8%
2,578,1740.0%0.50%
-28.3%
TELA TELA BIO INC  $48,774
8.1%
3,027,5420.0%0.49%
16.8%
APLT APPLIED THERAPEUTICS INC  $46,909
10.8%
2,257,3870.0%0.47%
19.7%
TERN TERNS PHARMACEUTICALS INC  $46,480
-44.3%
3,791,2040.0%0.47%
-39.7%
VTGN VISTAGEN THERAPEUTICS INCAdd  $45,574
148.7%
14,467,872
68.2%
0.46%
169.6%
NVAX NOVAVAX INCAdd  $42,525
50.5%
200,295
28.5%
0.43%
62.9%
DBTX DECIBEL THERAPEUTICS INC  $42,529
-24.3%
4,945,1920.0%0.43%
-18.1%
TCDA TRICIDA INC  $41,534
-18.3%
9,614,2800.0%0.42%
-11.8%
ORIC ORIC PHARMACEUTICALS INC  $41,352
-27.8%
2,337,5740.0%0.42%
-21.9%
IKNA IKENA ONCOLOGY INC  $41,193
-50.3%
2,933,9410.0%0.42%
-46.2%
SIBN SI-BONE INC  $41,078
-1.1%
1,305,3000.0%0.42%
7.0%
MRSN MERSANA THERAPEUTICS INCAdd  $38,027
24.2%
2,800,247
48.0%
0.38%
34.6%
GMTX GEMINI THERAPEUTICS INC  $37,696
-52.3%
5,826,2240.0%0.38%
-48.4%
LOGC LOGICBIO THERAPEUTICS INC  $37,593
-39.0%
8,466,7830.0%0.38%
-34.0%
VRNA VERONA PHARMA PLCsponsored ads  $37,244
-21.8%
5,694,8410.0%0.38%
-15.3%
HARP HARPOON THERAPEUTICS INCAdd  $36,219
-24.3%
2,611,308
14.2%
0.37%
-18.1%
NSTG NANOSTRING TECHNOLOGIE...Reduce  $36,023
-12.0%
556,000
-10.7%
0.36%
-5.0%
GRPH GRAPHITE BIO INCNew  $33,9971,106,3070.34%
TRILLIUM THERAPEUTICS INCAdd  $32,226
-5.2%
3,322,300
5.0%
0.33%
2.5%
GHRS GH RESEARCH PLCordinary sharesNew  $31,0451,428,6660.31%
CGEM CULLINAN ONCOLOGY INC  $29,513
-38.2%
1,146,1450.0%0.30%
-33.1%
SCPH SCPHARMACEUTICALS INC  $29,311
-8.1%
4,797,1480.0%0.30%
-0.7%
KALA KALA PHARMACEUTICALS INC  $28,965
-21.4%
5,465,0300.0%0.29%
-14.8%
SRRA SIERRA ONCOLOGY INC  $28,763
13.0%
1,477,3200.0%0.29%
22.3%
ARCT ARCTURUS THERAPEUTICS ...Reduce  $28,713
-42.4%
848,503
-29.7%
0.29%
-37.8%
FLDM FLUIDIGM CORP DELAdd  $28,717
38.1%
4,661,871
1.4%
0.29%
49.5%
CRIS CURIS INCReduce  $28,418
-42.5%
3,521,400
-19.4%
0.29%
-37.9%
AGLE AEGLEA BIOTHERAPEUTICS...  $27,948
-12.1%
4,015,5240.0%0.28%
-4.7%
ALXN ALEXION PHARMACEUTICAL...Add  $27,722
77.6%
150,900
47.8%
0.28%
91.8%
ALPN ALPINE IMMUNE SCIENCES...  $27,639
-15.1%
3,070,9550.0%0.28%
-7.9%
APTOSE BIOSCIENCES INC  $26,660
-44.4%
8,030,0000.0%0.27%
-39.9%
FUSN FUSION PHARMACEUTICALS...  $26,056
-24.6%
3,224,7700.0%0.26%
-18.3%
XENE XENON PHARMACEUTICALS INCReduce  $24,843
-44.4%
1,334,217
-46.6%
0.25%
-40.0%
BIIB BIOGEN INCReduce  $23,339
1.7%
67,400
-17.8%
0.24%
10.3%
FLXN FLEXION THERAPEUTICS INCAdd  $22,792
10.3%
2,769,383
20.0%
0.23%
19.7%
GRAY GRAYBUG VISION INC  $22,607
-2.2%
4,163,3470.0%0.23%
6.0%
OLMA OLEMA PHARMACEUTICALS INCAdd  $22,602
3.8%
807,792
23.1%
0.23%
12.3%
NXTC NEXTCURE INC  $21,769
-19.8%
2,711,0130.0%0.22%
-13.4%
CRVS CORVUS PHARMACEUTICALS...  $21,502
-13.3%
8,053,2980.0%0.22%
-6.5%
IMRA IMARA INC  $21,487
-6.4%
2,719,9020.0%0.22%
0.9%
PCVX VAXCYTE INCAdd  $21,281
66.1%
945,400
45.7%
0.22%
79.2%
GLTO GALECTO INC  $20,700
-16.7%
4,090,9370.0%0.21%
-9.9%
MGTA MAGENTA THERAPEUTICS INCAdd  $19,890
77.0%
2,033,759
114.3%
0.20%
91.4%
GILD GILEAD SCIENCES INC  $19,804
6.5%
287,6000.0%0.20%
14.9%
KDNY CHINOOK THERAPEUTICS INCAdd  $18,833
-3.0%
1,333,801
6.7%
0.19%
4.4%
CTIC CTI BIOPHARMA CORP  $18,802
-14.1%
7,520,6000.0%0.19%
-7.3%
VRCA VERRICA PHARMACEUTICAL...  $16,721
-25.4%
1,479,7330.0%0.17%
-19.5%
GLPG GALAPAGOS NVspon adr  $15,907
-10.6%
230,9050.0%0.16%
-3.0%
NAUT NAUTILUS BIOTECHNOLOGY...New  $15,6221,546,7000.16%
ACHL ACHILLES THERAPEUTICS PLCsponsored ads  $15,516
-40.8%
1,584,8450.0%0.16%
-35.9%
VOR VOR BIOPHARMA INC  $15,542
-56.7%
833,3330.0%0.16%
-53.3%
JNCE JOUNCE THERAPEUTICS INCAdd  $14,602
-22.0%
2,147,400
17.8%
0.15%
-15.4%
QURE UNIQURE NVReduce  $14,512
-55.6%
471,174
-51.4%
0.15%
-51.8%
SYBX SYNLOGIC INCAdd  $14,380
97.9%
3,696,662
82.1%
0.14%
113.2%
MIST MILESTONE PHARMACEUTIC...  $14,211
-5.0%
2,583,8210.0%0.14%
2.9%
AMGN AMGEN INCReduce  $13,918
-38.9%
57,100
-37.6%
0.14%
-33.8%
RLAY RELAY THERAPEUTICS INC  $12,807
5.8%
350,0000.0%0.13%
15.0%
ALEC ALECTOR INC  $12,737
3.4%
611,4780.0%0.13%
12.2%
PHGE BIOMX INC  $12,632
-23.3%
2,313,4890.0%0.13%
-16.9%
MAPS WM TECHNOLOGY INCNew  $12,509700,4000.13%
AVTE AEROVATE THERAPEUTICS INCNew  $12,230535,7140.12%
BLU BELLUS HEALTH INC NEW  $12,272
-18.7%
3,954,8000.0%0.12%
-12.1%
OCX ONCOCYTE CORP  $12,054
10.6%
2,100,0000.0%0.12%
19.6%
IPSC CENTURY THERAPEUTICS INCNew  $11,943407,0470.12%
CNVY CONVEY HLDG PARENT INCNew  $11,3801,000,0000.12%
CVRX CVRX INCNew  $11,200400,0000.11%
BSX BOSTON SCIEN... BSXcallNew  $10,690250,0000.11%
CVAC CUREVAC N V CVACputNew  $10,287140,0000.10%
SYRS SYROS PHARMACEUTICALS INC  $10,014
-27.1%
1,837,5000.0%0.10%
-21.7%
NANOSTRING TECHNOLOGIE...note 2.625% 3/0New  $9,7056,000,0000.10%
CTMX CYTOMX THERAPEUTICS INCNew  $9,5781,513,1680.10%
NMTR 9 METERS BIOPHARMA INCReduce  $9,423
-68.7%
8,565,974
-66.7%
0.10%
-66.2%
IMAB I MABsponsored adsAdd  $9,329
936.6%
111,120
498.5%
0.09%
1075.0%
CBIO CATALYST BIOSCIENCES INC  $9,174
-14.1%
2,118,6000.0%0.09%
-7.0%
XFOR X4 PHARMACEUTICALS INC  $8,930
-24.5%
1,373,8490.0%0.09%
-18.9%
ARPO AERPIO PHARMACEUTICALS...  $8,778
31.0%
5,193,9460.0%0.09%
41.3%
ASLN ASLAN PHARMACEUTICALS LTDads  $8,316
-1.5%
2,520,0000.0%0.08%
6.3%
ALXO ALX ONCOLOGY HLDGS INC  $8,202
-25.8%
150,0000.0%0.08%
-19.4%
STRO SUTRO BIOPHARMA INCAdd  $8,062
1.2%
433,700
23.9%
0.08%
10.8%
NRIX NURIX THERAPEUTICS INC  $7,959
-14.7%
300,0000.0%0.08%
-6.9%
LABP LANDOS BIOPHARMA INC  $7,866
19.9%
681,0000.0%0.08%
31.1%
GLUE MONTE ROSA THERAPEUTIC...New  $7,945350,0000.08%
DYN DYNE THERAPEUTICS INC  $7,364
35.5%
350,0000.0%0.07%
45.1%
OTIC OTONOMY INC  $7,248
-12.5%
3,250,0000.0%0.07%
-5.2%
NBTX NANOBIOTIX SAsponsored ads  $6,890
-8.4%
500,0000.0%0.07%0.0%
ACRS ACLARIS THERAPEUTICS INCNew  $6,357362,0000.06%
RXDX PROMETHEUS BIOSCIENCES...  $6,140
34.5%
250,0000.0%0.06%
44.2%
VERV VERVE THERAPEUTICS INCNew  $6,025100,0000.06%
LUNG PULMONX CORP  $5,515
-3.6%
125,0000.0%0.06%
5.7%
HSAQ HEALTH SCIENCES ACQ CO...  $5,100
-8.8%
500,0000.0%0.05%0.0%
SBBP STRONGBRIDGE BIOPHARMA...  $5,182
7.6%
1,744,6690.0%0.05%
15.6%
OGN ORGANON & CONew  $5,052166,9390.05%
SRPT SAREPTA THERAPEUTICS INCReduce  $5,030
-66.3%
64,700
-67.7%
0.05%
-63.6%
TARA PROTARA THERAPEUTICS INC  $4,383
-38.1%
450,0000.0%0.04%
-33.3%
ADAG ADAGENE INCads  $3,729
-24.5%
275,0000.0%0.04%
-17.4%
TALS TALARIS THERAPEUTICS INCNew  $3,632247,2400.04%
INZY INOZYME PHARMA INCNew  $3,216188,7040.03%
IFRX INFLARX NV  $3,160
-23.9%
1,064,1180.0%0.03%
-17.9%
KZR KEZAR LIFE SCIENCES INCNew  $3,026557,1910.03%
CVAC CUREVAC N V CVACcallNew  $2,20430,0000.02%
MAPSW WM TECHNOLOG... MAPSWcall*w exp 06/16/202New  $954150,2000.01%
LBPH LONGBOARD PHARMACEUTIC...Reduce  $1,035
-78.9%
113,500
-62.2%
0.01%
-78.3%
PPBT PURPLE BIOTECH LTDsponsored adsReduce  $86
-33.8%
17,712
-43.6%
0.00%0.0%
TRILLIUM THE... callSold out  $0-1,7000.00%
ARYA ARYA SCIENCES ACQUISIT...Sold out  $0-49,375-0.01%
SSPKW SILVER SPIKE ACQUISITI...*w exp 08/02/202Sold out  $0-150,200-0.01%
CVM CEL-SCI CORP CVMputSold out  $0-100,000-0.01%
SELB SELECTA BIOSCIENCES INCSold out  $0-339,169-0.01%
SANA SANA BIOTECHNOLOGY INCSold out  $0-60,000-0.02%
FLDM FLUIDIGM COR... FLDMcallSold out  $0-500,000-0.02%
AXSM AXSOME THERA... AXSMputSold out  $0-50,000-0.03%
CMPS COMPASS PATHWAYS PLCsponsored adsSold out  $0-127,816-0.04%
INNV INNOVAGE HLDG CORPSold out  $0-200,000-0.05%
FBRX FORTE BIOSCIENCES INCSold out  $0-159,664-0.05%
TCRR TCR2 THERAPEUTICS INCSold out  $0-249,279-0.05%
NTLA INTELLIA THERAPEUTICS INCSold out  $0-72,500-0.05%
SGFY SIGNIFY HEALTH INCSold out  $0-225,000-0.06%
NUVB NUVATION BIO INCSold out  $0-800,000-0.08%
HCAT HEALTH CATALYST INCSold out  $0-179,598-0.08%
LRMR LARIMAR THERAPEUTICS INCSold out  $0-617,245-0.08%
OLK OLINK HLDG ABsponsored adsSold out  $0-300,000-0.10%
SSPK SILVER SPIKE ACQUISITI...Sold out  $0-700,400-0.12%
TVTX TRAVERE THERAPEUTICS INCSold out  $0-528,100-0.12%
ALHC ALIGNMENT HEALTHCARE INCSold out  $0-800,000-0.16%
ALXN ALEXION PHAR... ALXNcallSold out  $0-150,000-0.21%
PAND PANDION THERAPEUTICS INCSold out  $0-528,229-0.30%
MOH MOLINA HEALTHCARE INCSold out  $0-162,400-0.36%
ADVM ADVERUM BIOTECHNOLOGIE...Sold out  $0-5,501,144-0.51%
HAE HAEMONETICS CORP MASSSold out  $0-852,000-0.88%
  • Orbimed Advisors Q2 2021 Portfolio
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  • Quarter
    Q2 2021
  • Total value
    $9.89 Billion
  • Holdings
    160
  • Turnover
    33.5%
  • EDGAR