Orbimed Advisors Q4 2021 holdings

$7.78 Billion is the total value of Orbimed Advisors's 159 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 25.6% .

 Value Shares↓ Weighting
SWTX  SPRINGWORKS THERAPEUTICS INC$373,634
-2.3%
6,028,3070.0%4.80%
+14.3%
BMY SellBRISTOL-MYERS SQUIBB CO$270,587
+1.3%
4,339,800
-3.9%
3.48%
+18.5%
HZNP SellHORIZON THERAPEUTICS PUB L$269,406
-5.8%
2,500,055
-4.2%
3.46%
+10.2%
BSX SellBOSTON SCIENTIFIC CORP$235,862
-6.8%
5,552,300
-4.8%
3.03%
+9.0%
NewTHESEUS PHARMACEUTICALS INC$213,51416,838,668
+100.0%
2.74%
EWTX  EDGEWISE THERAPEUTICS INC$213,075
-8.0%
13,944,6800.0%2.74%
+7.7%
MRTX BuyMIRATI THERAPEUTICS INC$209,239
-13.9%
1,426,400
+3.9%
2.69%
+0.7%
PMVP  PMV PHARMACEUTICALS INC$169,333
-22.5%
7,330,4230.0%2.18%
-9.3%
PFE NewPFIZER INC$154,4392,615,400
+100.0%
1.98%
 PRELUDE THERAPEUTICS INCnonvoting$148,660
-41.9%
11,895,6520.0%1.91%
-32.1%
HUM SellHUMANA INC$147,647
+13.3%
318,300
-5.0%
1.90%
+32.4%
ABBV SellABBVIE INC$144,716
-5.6%
1,068,800
-24.8%
1.86%
+10.5%
VRTX SellVERTEX PHARMACEUTICALS INC$144,519
-9.2%
658,100
-25.0%
1.86%
+6.2%
EW SellEDWARDS LIFESCIENCES CORP$139,422
+9.3%
1,076,200
-4.5%
1.79%
+27.9%
MRK SellMERCK & CO INC$136,366
-51.4%
1,779,300
-52.3%
1.75%
-43.1%
UNH SellUNITEDHEALTH GROUP INC$136,080
-10.6%
271,000
-30.5%
1.75%
+4.5%
ISRG BuyINTUITIVE SURGICAL INC$134,306
-3.2%
373,800
+167.8%
1.73%
+13.2%
NTRA SellNATERA INC$132,052
-24.7%
1,413,985
-10.1%
1.70%
-11.8%
ACET BuyADICET BIO INC$130,250
+129.7%
7,447,141
+3.0%
1.67%
+168.7%
ARQT  ARCUTIS BIOTHERAPEUTICS INC$125,972
-13.2%
6,073,8500.0%1.62%
+1.5%
PRLD  PRELUDE THERAPEUTICS INC$124,994
-60.2%
10,039,6910.0%1.61%
-53.4%
SYK BuySTRYKER CORPORATION$124,431
+39.8%
465,300
+37.9%
1.60%
+63.6%
GH  GUARDANT HEALTH INC$122,765
-20.0%
1,227,4000.0%1.58%
-6.4%
IOVA SellIOVANCE BIOTHERAPEUTICS INC$120,987
-26.2%
6,337,700
-4.6%
1.56%
-13.7%
XBI SellSPDR SER TRs&p biotech$113,046
-15.6%
1,009,700
-5.3%
1.45%
-1.3%
SGEN BuySEAGEN INC$101,356
+122.7%
655,600
+144.6%
1.30%
+160.6%
TPTX SellTURNING POINT THERAPEUTICS I$100,478
-35.9%
2,106,450
-10.8%
1.29%
-25.1%
HCA BuyHCA HEALTHCARE INC$100,070
+112.7%
389,500
+101.0%
1.29%
+148.9%
TCDA BuyTRICIDA INC$98,286
+120.3%
10,280,947
+6.9%
1.26%
+158.0%
KROS  KEROS THERAPEUTICS INC$98,263
+47.9%
1,679,4170.0%1.26%
+73.0%
CRNX BuyCRINETICS PHARMACEUTICALS IN$90,823
+44.0%
3,196,876
+6.7%
1.17%
+68.5%
MGTX SellMEIRAGTX HLDGS PLC$88,490
+63.6%
3,727,466
-9.2%
1.14%
+91.6%
DXCM SellDEXCOM INC$82,100
-34.2%
152,900
-32.9%
1.06%
-23.0%
NBIX SellNEUROCRINE BIOSCIENCES INC$79,371
-30.6%
931,915
-21.8%
1.02%
-18.8%
BMRN BuyBIOMARIN PHARMACEUTICAL INC$76,059
+787.4%
860,880
+676.3%
0.98%
+940.4%
SVA  SINOVAC BIOTECH LTD$72,700
-7.3%
2,839,5000.0%0.94%
+8.5%
ZBH SellZIMMER BIOMET HOLDINGS INC$71,689
-25.9%
564,300
-14.6%
0.92%
-13.3%
RPTX  REPARE THERAPEUTICS INC$70,071
-19.6%
3,322,4880.0%0.90%
-5.9%
CMPX NewCOMPASS THERAPEUTICS INC$68,60821,642,975
+100.0%
0.88%
KNTE  KINNATE BIOPHARMA INC$68,185
-23.0%
3,847,9290.0%0.88%
-9.9%
TBPH BuyTHERAVANCE BIOPHARMA INC$66,019
+51.3%
5,974,535
+1.3%
0.85%
+77.2%
TMO SellTHERMO FISHER SCIENTIFIC INC$63,188
+0.3%
94,700
-14.1%
0.81%
+17.2%
ABCL  ABCELLERA BIOLOGICS INC$59,785
-28.6%
4,180,7680.0%0.77%
-16.5%
SBTX  SILVERBACK THERAPEUTICS INC$58,214
-33.3%
8,740,8870.0%0.75%
-22.0%
ALPN  ALPINE IMMUNE SCIENCES INC$56,530
+29.8%
4,081,5920.0%0.73%
+51.8%
JANX SellJANUX THERAPEUTICS INC$55,962
-25.4%
2,836,386
-18.2%
0.72%
-12.7%
BIIB SellBIOGEN INC$55,230
-16.7%
230,200
-1.7%
0.71%
-2.5%
SIBN BuySI-BONE INC$51,201
+6.3%
2,305,300
+2.5%
0.66%
+24.4%
ETNB  89BIO INC$48,744
-33.3%
3,729,4420.0%0.63%
-21.9%
GRCL  GRACELL BIOTECHNOLOGIES INCsponsored ads$47,625
-56.5%
7,884,8700.0%0.61%
-49.1%
PASG  PASSAGE BIO INC$44,214
-36.2%
6,962,8990.0%0.57%
-25.5%
SNDX BuySYNDAX PHARMACEUTICALS INC$43,371
+1090.9%
1,981,300
+939.5%
0.56%
+1295.0%
OSH SellOAK STR HEALTH INC$42,761
-24.3%
1,290,300
-2.9%
0.55%
-11.4%
XTNT  XTANT MED HLDGS INC$40,809
-49.6%
72,873,4940.0%0.52%
-40.9%
NPCE  NEUROPACE INC$40,444
-36.4%
4,012,2810.0%0.52%
-25.6%
GLPG SellGALAPAGOS NVspon adr$39,542
+3.9%
717,257
-0.9%
0.51%
+21.5%
TELA  TELA BIO INC$38,753
-6.3%
3,027,5420.0%0.50%
+9.7%
VRNA  VERONA PHARMA PLCsponsored ads$38,269
+22.6%
5,694,8410.0%0.49%
+43.4%
IKNA  IKENA ONCOLOGY INC$36,792
-0.6%
2,933,9410.0%0.47%
+16.2%
SEM SellSELECT MED HLDGS CORP$36,268
-21.1%
1,233,600
-3.0%
0.47%
-7.7%
SellADAGIO THERAPEUTICS INC$36,180
-84.1%
4,983,500
-7.4%
0.46%
-81.4%
ORIC  ORIC PHARMACEUTICALS INC$34,362
-29.7%
2,337,5740.0%0.44%
-17.7%
NSTG BuyNANOSTRING TECHNOLOGIES INC$34,084
+27.7%
807,100
+45.2%
0.44%
+49.5%
GHRS BuyGH RESEARCH PLCordinary shares$33,332
+5.8%
1,428,732
+0.0%
0.43%
+24.0%
SRRA  SIERRA ONCOLOGY INC$32,117
-0.8%
1,477,3200.0%0.41%
+16.0%
 CYTEK BIOSCIENCES INC$31,386
-23.8%
1,923,1390.0%0.40%
-10.8%
IMGN SellIMMUNOGEN INC$28,706
-66.0%
3,868,786
-74.0%
0.37%
-60.2%
MREO NewMEREO BIOPHARMA GROUP PLCads$27,62417,264,764
+100.0%
0.36%
TERN  TERNS PHARMACEUTICALS INC$26,804
-32.1%
3,791,2040.0%0.34%
-20.5%
PCVX BuyVAXCYTE INC$26,090
-0.6%
1,096,700
+6.0%
0.34%
+16.3%
EVH BuyEVOLENT HEALTH INCcl a$25,954
+142.7%
938,000
+171.9%
0.33%
+183.1%
SellERASCA INC$25,983
-43.5%
1,667,693
-23.1%
0.33%
-33.9%
VECT BuyVECTIVBIO HLDG AG$25,649
-35.2%
5,223,804
+2.0%
0.33%
-24.1%
NewVENTYX BIOSCIENCES INC$25,6051,289,280
+100.0%
0.33%
VTGN  VISTAGEN THERAPEUTICS INC$25,173
-28.8%
12,909,2830.0%0.32%
-16.7%
THC SellTENET HEALTHCARE CORP$24,425
+17.9%
299,000
-4.1%
0.31%
+37.7%
OMIC BuySINGULAR GENOMICS SYSTEMS IN$24,326
+8.8%
2,104,359
+5.3%
0.31%
+27.2%
SCPH  SCPHARMACEUTICALS INC$24,082
-24.5%
4,797,1480.0%0.31%
-11.7%
JNCE BuyJOUNCE THERAPEUTICS INC$23,880
+21.0%
2,859,900
+7.7%
0.31%
+41.5%
KDNY SellCHINOOK THERAPEUTICS INC$23,132
+27.6%
1,418,300
-0.2%
0.30%
+49.2%
DBTX  DECIBEL THERAPEUTICS INC$22,995
-39.7%
4,945,1920.0%0.30%
-29.4%
HARP BuyHARPOON THERAPEUTICS INC$21,921
+6.3%
2,903,508
+11.2%
0.28%
+24.2%
GILD  GILEAD SCIENCES INC$20,883
+4.0%
287,6000.0%0.27%
+21.3%
APLT BuyAPPLIED THERAPEUTICS INC$20,707
-44.7%
2,313,681
+2.5%
0.27%
-35.4%
XENE BuyXENON PHARMACEUTICALS INC$19,712
+170.4%
631,000
+32.3%
0.25%
+216.2%
LOGC  LOGICBIO THERAPEUTICS INC$19,558
-49.6%
8,466,7830.0%0.25%
-41.1%
GRPH BuyGRAPHITE BIO INC$19,463
-18.1%
1,565,812
+8.0%
0.25%
-4.2%
MRSN  MERSANA THERAPEUTICS INC$17,969
-34.0%
2,888,8470.0%0.23%
-22.7%
CMMB  CHEMOMAB THERAPEUTICS LTDsponsored ads$17,789
-37.7%
2,578,1740.0%0.23%
-27.1%
DHRPRB NewDANAHER CORPORATION5% conv pfd b$17,38210,000
+100.0%
0.22%
CRIS BuyCURIS INC$17,302
-37.3%
3,634,800
+3.2%
0.22%
-26.7%
ILMN NewILLUMINA INC$17,15845,100
+100.0%
0.22%
MIST  MILESTONE PHARMACEUTICALS IN$16,924
+14.7%
2,583,8210.0%0.22%
+34.6%
GMTX  GEMINI THERAPEUTICS INC$16,954
-28.0%
5,826,2240.0%0.22%
-15.8%
CRVS  CORVUS PHARMACEUTICALS INC$16,734
-50.2%
6,943,6540.0%0.22%
-41.7%
NXTC  NEXTCURE INC$16,266
-11.0%
2,711,0130.0%0.21%
+4.0%
CLDX SellCELLDEX THERAPEUTICS INC NEW$15,692
-29.8%
406,100
-2.0%
0.20%
-17.9%
BuyRXSIGHT INC$15,564
-1.7%
1,383,500
+10.7%
0.20%
+14.9%
FLDM SellFLUIDIGM CORP DEL$14,972
-50.6%
3,819,348
-17.0%
0.19%
-42.3%
SYBX  SYNLOGIC INC$14,593
-20.7%
6,029,9950.0%0.19%
-6.9%
ACRS BuyACLARIS THERAPEUTICS INC$14,335
+22.2%
985,900
+51.3%
0.18%
+42.6%
AGLE SellAEGLEA BIOTHERAPEUTICS INC$14,042
-56.0%
2,956,124
-26.4%
0.18%
-48.4%
CTMX BuyCYTOMX THERAPEUTICS INC$13,919
+50.1%
3,214,509
+76.4%
0.18%
+75.5%
LUNG  PULMONX CORP$13,950
-10.9%
435,0000.0%0.18%
+4.1%
BNR SellBURNING ROCK BIOTECH LTDsponsored ads$13,841
-58.3%
1,452,402
-21.8%
0.18%
-51.2%
FUSN  FUSION PHARMACEUTICALS INC$13,447
-47.3%
3,224,7700.0%0.17%
-38.4%
AMGN  AMGEN INC$12,846
+5.8%
57,1000.0%0.16%
+24.1%
CLXPF SellCYBIN INC$12,481
-57.6%
10,524,300
-21.7%
0.16%
-50.6%
CGEM SellCULLINAN ONCOLOGY INC$12,422
-52.0%
805,041
-29.8%
0.16%
-43.7%
GLTO  GALECTO INC$12,396
-15.6%
4,090,9370.0%0.16%
-1.2%
QURE  UNIQURE NV$12,145
-35.2%
585,5740.0%0.16%
-24.3%
BLU SellBELLUS HEALTH INC NEW$11,698
-21.8%
1,454,800
-40.7%
0.15%
-8.5%
NewSONENDO INC$11,3371,968,180
+100.0%
0.15%
NMTR Buy9 METERS BIOPHARMA INC$10,057
-9.7%
10,275,887
+20.0%
0.13%
+5.7%
MGTA BuyMAGENTA THERAPEUTICS INC$9,972
-27.6%
2,250,953
+18.9%
0.13%
-15.2%
RXDX  PROMETHEUS BIOSCIENCES INC$9,885
+66.8%
250,0000.0%0.13%
+95.4%
IMRA  IMARA INC$9,870
-44.9%
4,386,5680.0%0.13%
-35.5%
VOR  VOR BIOPHARMA INC$9,683
-25.9%
833,3330.0%0.12%
-13.9%
AFIB  ACUTUS MED INC$9,031
-61.4%
2,648,3860.0%0.12%
-54.9%
CVRX SellCVRX INC$8,843
-33.2%
723,055
-9.6%
0.11%
-21.4%
ACHL  ACHILLES THERAPEUTICS PLCsponsored ads$7,940
-35.7%
1,584,8450.0%0.10%
-25.0%
RAPT NewRAPT THERAPEUTICS INC$7,970217,000
+100.0%
0.10%
GOSS NewGOSSAMER BIO INC$7,725683,000
+100.0%
0.10%
GRAY  GRAYBUG VISION INC$7,619
-44.9%
4,163,3470.0%0.10%
-35.5%
OCX BuyONCOCYTE CORP$7,582
-25.4%
3,493,800
+22.3%
0.10%
-13.4%
NAUT  NAUTILUS BIOTECHNOLOGY INC$7,525
-15.6%
1,452,7740.0%0.10%
-1.0%
 NANOSTRING TECHNOLOGIES INCnote 2.625% 3/0$7,172
-8.7%
6,000,0000.0%0.09%
+7.0%
AVTE  AEROVATE THERAPEUTICS INC$6,316
-43.8%
535,7140.0%0.08%
-34.7%
NTLA  INTELLIA THERAPEUTICS INC$6,290
-11.9%
53,2000.0%0.08%
+3.8%
SYRS  SYROS PHARMACEUTICALS INC$5,990
-27.1%
1,837,5000.0%0.08%
-14.4%
TARA BuyPROTARA THERAPEUTICS INC$5,607
+80.1%
830,641
+84.6%
0.07%
+111.8%
NRIX SellNURIX THERAPEUTICS INC$5,340
-69.2%
184,468
-68.1%
0.07%
-63.7%
SRPT SellSAREPTA THERAPEUTICS INC$5,286
-11.6%
58,700
-9.3%
0.07%
+3.0%
IMAB  I MABsponsored ads$5,266
-34.6%
111,1200.0%0.07%
-23.6%
HSAQ  HEALTH SCIENCES ACQ CORP 2$5,040
+1.9%
500,0000.0%0.06%
+20.4%
IPSC SellCENTURY THERAPEUTICS INC$4,870
-52.4%
307,047
-24.6%
0.06%
-44.2%
PHGE  BIOMX INC$4,502
-47.7%
2,813,4890.0%0.06%
-38.9%
ALXO BuyALX ONCOLOGY HLDGS INC$4,461
-59.7%
207,600
+38.4%
0.06%
-53.3%
IFRX SellINFLARX NV$4,166
+51.2%
875,297
-17.7%
0.05%
+80.0%
TALS  TALARIS THERAPEUTICS INC$3,780
+12.7%
247,2400.0%0.05%
+32.4%
 FIELD TRIP HEALTH LTD$3,722
-46.8%
1,538,4700.0%0.05%
-37.7%
INZY BuyINOZYME PHARMA INC$3,591
+5.4%
526,600
+79.1%
0.05%
+24.3%
 SIGHT SCIENCES INC$3,514
-22.6%
200,0000.0%0.04%
-10.0%
SellAADI BIOSCIENCE INC$3,082
-69.7%
127,600
-63.1%
0.04%
-64.3%
XFOR  X4 PHARMACEUTICALS INC$3,146
-56.7%
1,373,8490.0%0.04%
-50.0%
NewEXSCIENTIA PLCads$2,470125,000
+100.0%
0.03%
SURF SellSURFACE ONCOLOGY INC$2,237
-67.5%
467,945
-48.6%
0.03%
-61.8%
ASLN  ASLAN PHARMACEUTICALS LTDads$2,206
-37.1%
1,970,0000.0%0.03%
-28.2%
NewBRIGHT MINDS BIOSCIENCES INC$2,131660,600
+100.0%
0.03%
ADAG SellADAGENE INCads$2,123
-46.3%
263,176
-4.3%
0.03%
-37.2%
APTX BuyAPTINYX INC$2,001
+457.4%
749,500
+389.0%
0.03%
+550.0%
CBIO SellCATALYST BIOSCIENCES INC$1,581
-85.8%
1,729,402
-36.2%
0.02%
-83.6%
NewPYXIS ONCOLOGY INC$1,576143,640
+100.0%
0.02%
LABP  LANDOS BIOPHARMA INC$1,359
-67.1%
283,2170.0%0.02%
-62.2%
CABA  CABALETTA BIO INC$1,147
-68.8%
302,5090.0%0.02%
-62.5%
LBPH  LONGBOARD PHARMACEUTICALS IN$554
-44.8%
113,5000.0%0.01%
-36.4%
AUGX NewAUGMEDIX INC$27888,363
+100.0%
0.00%
NewOWLET INC*w exp 09/14/202$86220,704
+100.0%
0.00%
ExitOWLET INCcall$0-220,704
-100.0%
-0.00%
AZN ExitASTRAZENECA PLCcall$0-5,200
-100.0%
-0.00%
PHAS ExitPHASEBIO PHARMACEUTICALS INC$0-177,113
-100.0%
-0.01%
MAPSW ExitWM TECHNOLOGY INCcall$0-150,200
-100.0%
-0.01%
KZR ExitKEZAR LIFE SCIENCES INCcall$0-113,400
-100.0%
-0.01%
SBBP ExitSTRONGBRIDGE BIOPHARMA PLC$0-794,675
-100.0%
-0.02%
RGEN ExitREPLIGEN CORP$0-14,724
-100.0%
-0.05%
ExitPROCEPT BIOROBOTICS CORP$0-135,000
-100.0%
-0.06%
ExitAPTOSE BIOSCIENCES INC$0-2,594,348
-100.0%
-0.06%
NBTX ExitNANOBIOTIX SAsponsored ads$0-500,000
-100.0%
-0.06%
ExitOWLET INC$0-1,200,000
-100.0%
-0.07%
EVH ExitEVOLENT HEALTH INCcall$0-250,000
-100.0%
-0.08%
REGN ExitREGENERON PHARMACEUTICALS$0-13,560
-100.0%
-0.09%
CNVY ExitCONVEY HLDG PARENT INC$0-1,000,000
-100.0%
-0.09%
KALA ExitKALA PHARMACEUTICALS INC$0-3,438,998
-100.0%
-0.10%
NVAX ExitNOVAVAX INC$0-45,580
-100.0%
-0.10%
KZR ExitKEZAR LIFE SCIENCES INC$0-1,150,000
-100.0%
-0.11%
MAPS ExitWM TECHNOLOGY INC$0-700,400
-100.0%
-0.11%
ExitDICE THERAPEUTICS INC$0-440,000
-100.0%
-0.16%
FLXN ExitFLEXION THERAPEUTICS INC$0-2,769,383
-100.0%
-0.19%
ExitHUMACYTE INC$0-1,500,000
-100.0%
-0.19%
VRCA ExitVERRICA PHARMACEUTICALS INC$0-1,479,733
-100.0%
-0.20%
CTIC ExitCTI BIOPHARMA CORP$0-7,520,600
-100.0%
-0.24%
OLMA ExitOLEMA PHARMACEUTICALS INC$0-807,792
-100.0%
-0.24%
MREO ExitMEREO BIOPHARMA GROUP PLCads$0-17,264,764
-100.0%
-0.46%
CRSP ExitCRISPR THERAPEUTICS AGnamen akt$0-612,700
-100.0%
-0.75%
PGNY ExitPROGYNY INC$0-1,270,045
-100.0%
-0.78%
DCPH ExitDECIPHERA PHARMACEUTICALS IN$0-2,183,143
-100.0%
-0.82%
ANTM ExitANTHEM INC$0-207,100
-100.0%
-0.85%
Other reporting managers
Signed by
  • Sven H. Borho — Member

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