| NEXT CENTURY GROWTH INVESTORS LLC | 1,581,634 | $40,458,197 | 3.90% |
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| Millrace Asset Group, Inc. | 72,207 | $1,847 | 1.94% |
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| Perceptive Advisors | 2,217,250 | $56,717,255 | 1.64% |
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| SECTORAL ASSET MANAGEMENT INC | 379,443 | $9,706,152 | 1.62% |
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| EMERALD MUTUAL FUND ADVISERS TRUST | 1,120,875 | $28,671,983 | 1.56% |
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| EMERALD ADVISERS, LLC | 1,366,138 | $34,945,810 | 1.53% |
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| FORMULA GROWTH LTD | 117,750 | $3,012,045 | 0.96% |
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| OBERWEIS ASSET MANAGEMENT INC/ | 251,500 | $6,433,370 | 0.78% |
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| Novo Holdings A/S | 360,000 | $9,208,800 | 0.71% |
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| Intrinsic Edge Capital Management LLC | 354,585 | $9,070,284 | 0.65% |
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| Lisanti Capital Growth, LLC | 179,605 | $4,594,296 | 0.64% |
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| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,477,116 | $37,784,627 | 0.48% |
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| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 391,869 | $10,024,009 | 0.37% |
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| KORNITZER CAPITAL MANAGEMENT INC /KS | 634,223 | $16,223,424 | 0.32% |
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| TimesSquare Capital Management, LLC | 848,890 | $21,715 | 0.31% |
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| OAK RIDGE INVESTMENTS LLC | 92,741 | $2,372,315 | 0.29% |
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| PEREGRINE CAPITAL MANAGEMENT LLC | 280,091 | $7,164,728 | 0.20% |
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| CASTLEARK MANAGEMENT LLC | 123,780 | $3,166,292 | 0.14% |
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| Point72 Asset Management, L.P. | 1,418,544 | $36,286,356 | 0.11% |
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| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 112,453 | $2,876,548 | 0.09% |
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