| Cormorant Asset Management, LP | 2,353,141 | $13,083,464 | 0.76% |
|---|
| Integral Health Asset Management, LLC | 760,000 | $4,225,600 | 0.58% |
|---|
| Prosight Management, LP | 321,154 | $1,785,616 | 0.57% |
|---|
| Parkman Healthcare Partners LLC | 355,957 | $1,979,121 | 0.36% |
|---|
| Ikarian Capital, LLC | 514,101 | $2,858,401 | 0.34% |
|---|
| FARALLON CAPITAL MANAGEMENT LLC | 1,560,500 | $8,676,380 | 0.04% |
|---|
| Polar Capital Holdings Plc | 1,000,000 | $5,560,000 | 0.04% |
|---|
| UBS OCONNOR LLC | 262,265 | $1,458,193 | 0.04% |
|---|
| BOOTHBAY FUND MANAGEMENT, LLC | 112,614 | $626,134 | 0.02% |
|---|
| Point72 Asset Management, L.P. | 825,000 | $4,587,000 | 0.01% |
|---|
| BOURGEON CAPITAL MANAGEMENT LLC | 7,000 | $38,920 | 0.01% |
|---|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 50,000 | $278,000 | 0.01% |
|---|
| Woodline Partners LP | 81,279 | $451,911 | 0.01% |
|---|
| Dorsey Wright & Associates | 3,045 | $16,930 | 0.01% |
|---|
| MOORE CAPITAL MANAGEMENT, LP | 45,728 | $254,248 | 0.01% |
|---|
| Schonfeld Strategic Advisors LLC | 84,000 | $467,040 | 0.00% |
|---|
| CIBC Asset Management Inc | 144,571 | $803,815 | 0.00% |
|---|
| TD ASSET MANAGEMENT INC | 121,422 | $675,106 | 0.00% |
|---|
| Tower Research Capital LLC (TRC) | 4,295 | $23,880 | 0.00% |
|---|
| FMR LLC | 2,113,073 | $11,748,686 | 0.00% |
|---|