| 2024-04-25 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 20000.0 | 3,815,000 | $10.0 | P |
| 2024-04-24 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 8285.0 | 3,795,000 | $10.2 | P |
| 2024-04-23 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 11715.0 | 3,786,715 | $10.3 | P |
| 2024-04-19 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 29400.0 | 3,775,000 | $10.6 | P |
| 2024-03-28 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 50000.0 | 3,745,600 | $12.8 | P |
| 2024-03-22 | BAUM MARK L | | Buy | Common stock | 9000.0 | 2,137,525 | $11.6 | P |
| 2024-03-20 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 50600.0 | 3,695,600 | $9.7 | P |
| 2024-03-01 | SAHAREK JOHN P. | | Buy | Common stock | 5000.0 | 254,803 | $8.8 | M |
| 2024-02-20 | SAHAREK JOHN P. | | Buy | Common stock | 30000.0 | 262,419 | $10.7 | M |
| 2024-02-20 | BAUM MARK L | | Buy | Common stock | 150000.0 | 2,188,361 | $10.7 | M |
| 2024-02-20 | BOLL ANDREW R. | | Buy | Common stock | 45000.0 | 586,569 | $10.7 | M |
| 2024-02-07 | BAUM MARK L | | Buy | Common stock | 15400.0 | 2,038,361 | $7.7 | M |
| 2024-02-07 | BOLL ANDREW R. | | Buy | Common stock | 7400.0 | 541,569 | $7.7 | M |
| 2024-01-26 | Graves Adrienne L | | Buy | RSU | 3119.0 | 3,119 | $0.0 | A |
| 2024-01-26 | SILVERNAIL LAUREN P | | Buy | RSU | 3119.0 | 3,119 | $0.0 | A |
| 2023-11-16 | BAUM MARK L | | Buy | Common Stock | 7500.0 | 2,022,961 | $8.1 | P |
| 2023-11-15 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 25000.0 | 3,645,000 | $8.0 | P |
| 2023-11-10 | SAHAREK JOHN P. | | Buy | Common Stock | 20000.0 | 242,197 | $0.0 | M |
| 2023-09-20 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 5983.0 | 3,620,000 | $14.5 | P |
| 2023-09-19 | Opaleye Management Inc. | | Buy | Common Stock, par value $0.001 per share | 14017.0 | 3,614,017 | $14.7 | P |