$378 Million is the total value of INTERNATIONAL BIOTECHNOLOGY TRUST PLC's 56 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 26.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HZNP | Sell | HORIZON THERAPEUTICS PUB LTD | $36,176,000 | +11.4% | 393,000 | -11.5% | 9.57% | +7.8% |
| GILD | Buy | Gilead Sciences Inc | $25,059,000 | +23.5% | 387,784 | +11.3% | 6.63% | +19.6% |
| REGN | Buy | Regeneron Pharmaceuticals | $20,723,000 | +273.5% | 43,800 | +280.9% | 5.48% | +261.5% |
| NBIX | Buy | Neurocrine Biosciences Inc | $20,125,000 | +775.4% | 207,000 | +762.5% | 5.32% | +747.6% |
| EXEL | Buy | Exelixis Inc | $20,027,000 | +89.5% | 886,534 | +68.4% | 5.30% | +83.5% |
| PTCT | Buy | PTC Therapuetics COM | $19,319,000 | -4.9% | 408,000 | +22.5% | 5.11% | -7.9% |
| SGEN | Buy | SEAGEN INC | $18,464,000 | +61.0% | 133,000 | +103.1% | 4.88% | +55.9% |
| VRTX | Sell | Vertex Pharmaceuticals Inc | $18,331,000 | -20.2% | 85,322 | -12.3% | 4.85% | -22.8% |
| ALNY | Buy | Alnylam Pharmaceuticals Inc | $15,360,000 | +225.6% | 108,800 | +199.7% | 4.06% | +215.2% |
| IONS | Buy | Ionis Pharmaceuticals Inc | $15,003,000 | +241.1% | 333,781 | +329.1% | 3.97% | +230.4% |
| CCXI | Buy | CHEMOCENTRYX INC | $14,779,000 | -6.4% | 288,600 | +12.9% | 3.91% | -9.3% |
| BIIB | Buy | Biogen Inc | $13,568,000 | +69.2% | 48,500 | +47.9% | 3.59% | +63.9% |
| BHVN | Sell | BIOHAVEN PHARMACTL HLDG CO L | $12,057,000 | -29.8% | 176,400 | -12.0% | 3.19% | -32.0% |
| MRTX | MIRATI THERAPEUTICS INC | $11,536,000 | -22.1% | 67,400 | 0.0% | 3.05% | -24.5% | |
| AMGN | Sell | Amgen Inc | $10,699,000 | -35.3% | 43,000 | -40.3% | 2.83% | -37.4% |
| QURE | Buy | UNIQURE NV | $9,490,000 | +854.7% | 282,034 | +925.6% | 2.51% | +826.2% |
| XLRN | Sell | ACCELERON PHARMA INC | $8,199,000 | -9.5% | 60,500 | -14.8% | 2.17% | -12.4% |
| TPTX | Sell | TURNING POINT THERAPEUTICS I | $7,711,000 | -44.2% | 81,541 | -28.2% | 2.04% | -45.9% |
| INCY | Incyte Corp | $6,339,000 | -6.4% | 78,000 | 0.0% | 1.68% | -9.4% | |
| ILMN | New | ILLUMINA INC | $6,260,000 | – | 16,300 | +100.0% | 1.66% | – |
| KALV | Buy | Kalvista Pharmaceuticals Inc | $5,486,000 | +62.8% | 214,533 | +20.9% | 1.45% | +57.7% |
| DCPH | Buy | DECIPHERA PHARMACEUTICALS INC | $4,484,000 | +57.2% | 100,000 | +100.0% | 1.19% | +52.2% |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $4,449,000 | – | 26,600 | +100.0% | 1.18% | – |
| BMRN | Sell | Biomarin Pharmaceutical Inc | $4,165,000 | -80.8% | 55,156 | -77.7% | 1.10% | -81.4% |
| PTGX | PROTAGONIST THERAPEUTICS INC | $3,937,000 | +28.5% | 152,000 | 0.0% | 1.04% | +24.4% | |
| AUPH | Buy | AURINIA PHARMACEUTICALS INC | $3,875,000 | +257.1% | 298,500 | +280.3% | 1.02% | +246.3% |
| STRO | SUTRO BIOPHARMA INC | $3,171,000 | +5.2% | 139,331 | 0.0% | 0.84% | +1.9% | |
| ITCI | INTRA CELLULAR THERAPIES INC | $2,700,000 | +6.8% | 79,456 | 0.0% | 0.71% | +3.5% | |
| CRSP | CRISPR THERAPEUTICS AGnamen akt | $2,681,000 | -20.4% | 22,000 | 0.0% | 0.71% | -22.9% | |
| SRPT | Sarepta Therapeutics Inc | $2,348,000 | -56.2% | 31,500 | 0.0% | 0.62% | -57.6% | |
| RARE | New | ULTRAGENYX PHARMACEUTICAL IN | $2,285,000 | – | 20,100 | +100.0% | 0.60% | – |
| BPMC | Blueprint Medicines Corp | $1,896,000 | -13.3% | 19,500 | 0.0% | 0.50% | -16.1% | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | $1,836,000 | -31.8% | 58,000 | 0.0% | 0.49% | -33.9% | |
| ALLK | ALLAKOS INC | $1,801,000 | -17.9% | 15,700 | 0.0% | 0.48% | -20.5% | |
| ASND | Ascendis Pharma ASsponsored adr | $1,775,000 | -22.8% | 13,800 | 0.0% | 0.47% | -25.3% | |
| IMAB | New | I MABsponsored ads | $1,692,000 | – | 35,000 | +100.0% | 0.45% | – |
| SAGE | New | SAGE THERAPEUTICS INC | $1,609,000 | – | 21,500 | +100.0% | 0.43% | – |
| ACAD | Sell | ACADIA PHARMACEUTICALS INC | $1,534,000 | -94.1% | 59,514 | -87.8% | 0.41% | -94.3% |
| ARNA | New | Arena Pharmaceuticals Inc | $1,457,000 | – | 21,000 | +100.0% | 0.38% | – |
| DYN | New | DYNE THERAPEUTICS INC | $1,453,000 | – | 93,886 | +100.0% | 0.38% | – |
| HALO | Sell | Halozyme Therapeutics Inc | $1,444,000 | -89.0% | 34,633 | -88.7% | 0.38% | -89.4% |
| EXAS | Exact Sciences Corp | $1,410,000 | -0.6% | 10,700 | 0.0% | 0.37% | -3.6% | |
| NKTR | NEKTAR THERAPEUTICS | $1,340,000 | +17.6% | 67,000 | 0.0% | 0.35% | +13.8% | |
| ORIC | ORIC PHARMACEUTICALS INC | $1,298,000 | -27.4% | 53,000 | 0.0% | 0.34% | -29.9% | |
| INSM | INSMED INC | $1,144,000 | +2.2% | 33,600 | 0.0% | 0.30% | -1.0% | |
| AGIO | Agios Pharmaceuticals Inc | $1,108,000 | +18.9% | 21,500 | 0.0% | 0.29% | +14.9% | |
| APLS | New | APELLIS PHARMACEUTICALS INCcm | $1,001,000 | – | 23,400 | +100.0% | 0.26% | – |
| FOLD | Amicus Therapeutics Inc | $935,000 | -57.2% | 94,600 | 0.0% | 0.25% | -58.6% | |
| GBT | Global Blood Therapeutics | $888,000 | -5.9% | 21,800 | 0.0% | 0.24% | -8.9% | |
| GMDA | New | GAMIDA CELL LTD | $862,000 | – | 107,000 | +100.0% | 0.23% | – |
| AXSM | AXSOME THERAPEUTICS INC | $793,000 | -30.4% | 14,000 | 0.0% | 0.21% | -32.5% | |
| FGEN | FibroGen Inc | $684,000 | -6.4% | 19,700 | 0.0% | 0.18% | -9.5% | |
| TVTX | TRAVERE THERAPEUTICS INC | $499,000 | -8.4% | 20,000 | 0.0% | 0.13% | -11.4% | |
| BLUE | Bluebird Bio Inc | $332,000 | -30.3% | 11,000 | 0.0% | 0.09% | -32.3% | |
| ESPR | ESPERION THERAPEUTICS INC NE | $266,000 | +7.7% | 9,500 | 0.0% | 0.07% | +4.5% | |
| ANAB | ANAPTYSBIO INC | $216,000 | +0.5% | 10,000 | 0.0% | 0.06% | -3.4% | |
| ZEAL | Exit | ZEALAND PHARMA A Ssponsored adr | $0 | – | -5,653 | -100.0% | -0.06% | – |
| GWPH | Exit | GW Pharmaceuticals Plcads | $0 | – | -10,200 | -100.0% | -0.32% | – |
| Exit | Arena Pharmaceuticals Inc | $0 | – | -21,000 | -100.0% | -0.44% | – | |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -72,000 | -100.0% | -0.52% | – |
| ALXN | Exit | Alexion Pharmaceuticals Inc | $0 | – | -99,241 | -100.0% | -4.23% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-17
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| GILEAD SCIENCES INC COMMO | 28 | Q3 2023 | 9.3% |
| INCYTE CORP INC COM | 28 | Q3 2023 | 7.9% |
| BIOMARIN PHARMACEUTICALS INC | 28 | Q3 2023 | 7.5% |
| REGENERON PHARMS. | 27 | Q3 2023 | 9.0% |
| BIOGEN INC COMMON STOCK | 26 | Q3 2023 | 8.7% |
| VERTEX PHARMS. | 25 | Q3 2023 | 8.4% |
| AMGEN INC COM | 25 | Q3 2023 | 7.9% |
| NEUROCRINE BIOSCIENCES INC | 25 | Q3 2023 | 6.9% |
| ALYNYLAM PHARMACEUTICALS INC | 25 | Q3 2023 | 6.7% |
| IONIS PHARMS. | 25 | Q3 2023 | 4.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Altus Pharmaceuticals Inc. | February 12, 2009 | ? | ? |
| MICROMET, INC. | February 14, 2008 | 1,907,390 | 4.7% |
| EPIMMUNE INC | February 15, 2005 | 1,279,659 | 8.0% |
| ESSENTIAL THERAPEUTICS INC | April 29, 2003 | 2,500,000 | 11.7% |
| TARGETED GENETICS CORP /WA/ | April 18, 2003 | ? | ? |
| ESSENTIAL THERAPEUTICS INC | November 05, 2001 | 11 | 13.0% |
| ONYX PHARMACEUTICALS INC | October 15, 2001 | 11 | 13.0% |
| CORVAS INTERNATIONAL INC | October 12, 2001 | 11 | 13.0% |
| RIBOZYME PHARMACEUTICALS INC | October 05, 2001 | 11 | 13.0% |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-08 |
| 13F-HR | 2023-05-18 |
| 13F-HR | 2023-02-01 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-16 |
| 13F-HR | 2022-05-20 |
| 13F-HR | 2022-02-15 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
View INTERNATIONAL BIOTECHNOLOGY TRUST PLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.