$296 Million is the total value of SILVERARC CAPITAL MANAGEMENT, LLC's 79 reported holdings in Q3 2022. The portfolio turnover from Q2 2022 to Q3 2022 was 70.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BLU | Buy | BELLUS HEALTH INC NEW | $17,485,000 | +21.1% | 1,655,775 | +5.9% | 5.91% | +33.0% |
| RLMD | New | RELMADA THERAPEUTICS INCput | $14,549,000 | – | 393,000 | +100.0% | 4.92% | – |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INCput | $12,079,000 | +41.8% | 204,700 | -32.2% | 4.09% | +55.8% |
| VCYT | Sell | VERACYTE INC | $11,053,000 | -22.7% | 665,854 | -7.4% | 3.74% | -15.1% |
| AKRO | Buy | AKERO THERAPEUTICS INC | $10,215,000 | +315.2% | 300,000 | +15.2% | 3.46% | +356.4% |
| AVXL | Buy | ANAVEX LIFE SCIENCES CORPput | $9,727,000 | +6.0% | 942,500 | +2.8% | 3.29% | +16.4% |
| MORF | Sell | MORPHIC HLDG INC | $9,181,000 | +1.1% | 324,421 | -22.5% | 3.10% | +11.0% |
| COGT | Sell | COGENT BIOSCIENCES INC | $9,051,000 | +22.2% | 606,608 | -26.1% | 3.06% | +34.3% |
| PSTX | Buy | POSEIDA THERAPEUTICS INC | $9,017,000 | +818.2% | 2,554,277 | +571.1% | 3.05% | +909.9% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $8,880,000 | +25.5% | 245,992 | +5.7% | 3.00% | +37.9% |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $8,559,000 | +13.6% | 543,776 | +0.8% | 2.90% | +24.8% |
| VRAY | Buy | VIEWRAY INC | $8,460,000 | +335.6% | 2,324,066 | +217.2% | 2.86% | +378.6% |
| ISEE | Buy | IVERIC BIO INCput | $7,949,000 | +91.8% | 443,100 | +2.8% | 2.69% | +110.7% |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $6,720,000 | +71.1% | 994,073 | +16.9% | 2.27% | +88.0% |
| PRTA | New | PROTHENA CORP PLC | $6,669,000 | – | 110,000 | +100.0% | 2.26% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $6,514,000 | – | 32,545 | +100.0% | 2.20% | – |
| VERU | Sell | VERU INCput | $6,336,000 | -28.2% | 550,000 | -29.5% | 2.14% | -21.1% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES INC | $6,334,000 | -64.7% | 136,126 | -56.6% | 2.14% | -61.2% |
| APEN | Buy | APOLLO ENDOSURGERY INC | $6,260,000 | +59.6% | 1,136,206 | +5.7% | 2.12% | +75.2% |
| MRUS | Sell | MERUS N V | $5,912,000 | -44.3% | 295,136 | -37.1% | 2.00% | -38.8% |
| CERS | Sell | CERUS CORP | $5,819,000 | -47.5% | 1,616,459 | -22.8% | 1.97% | -42.3% |
| CTIC | Sell | CTI BIOPHARMA CORP | $5,724,000 | -30.5% | 983,516 | -28.7% | 1.94% | -23.7% |
| CLNN | New | CLENE INCput | $4,857,000 | – | 1,734,800 | +100.0% | 1.64% | – |
| INSM | Buy | INSMED INC | $4,825,000 | +15.2% | 224,016 | +5.4% | 1.63% | +26.5% |
| NKTX | Buy | NKARTA INC | $4,769,000 | +249.4% | 362,377 | +227.2% | 1.61% | +284.0% |
| PLRX | New | PLIANT THERAPEUTICS INC | $4,383,000 | – | 209,822 | +100.0% | 1.48% | – |
| ABOS | New | ACUMEN PHARMACEUTICALS INC | $4,213,000 | – | 420,000 | +100.0% | 1.42% | – |
| KRYS | Sell | KRYSTAL BIOTECH INC | $3,948,000 | -42.9% | 56,645 | -46.2% | 1.34% | -37.3% |
| ORIC | Buy | ORIC PHARMACEUTICALS INC | $3,869,000 | -20.2% | 1,208,992 | +11.7% | 1.31% | -12.3% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $3,215,000 | +9.5% | 11,105 | +6.6% | 1.09% | +20.2% |
| ISEE | New | IVERIC BIO INC | $3,182,000 | – | 177,364 | +100.0% | 1.08% | – |
| MRTX | Sell | MIRATI THERAPEUTICS INCcall | $2,968,000 | -56.2% | 42,500 | -57.9% | 1.00% | -51.8% |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $2,927,000 | +12.5% | 149,027 | +6.8% | 0.99% | +23.6% |
| RGNX | Buy | REGENXBIO INC | $2,910,000 | +13.1% | 110,085 | +5.7% | 0.98% | +24.2% |
| CGEM | Buy | CULLINAN ONCOLOGY INC | $2,879,000 | +5.4% | 224,555 | +5.4% | 0.97% | +15.8% |
| CVRX | Buy | CVRX INC | $2,873,000 | +63.6% | 307,920 | +5.4% | 0.97% | +79.7% |
| LVTX | New | LAVA THERAPEUTICS NV | $2,791,000 | – | 610,809 | +100.0% | 0.94% | – |
| ALLK | New | ALLAKOS INC | $2,448,000 | – | 400,000 | +100.0% | 0.83% | – |
| MCRB | Buy | SERES THERAPEUTICS INC | $2,353,000 | +97.2% | 366,493 | +5.4% | 0.80% | +116.9% |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $2,351,000 | +315.4% | 186,603 | +248.7% | 0.80% | +356.9% |
| KRTX | New | KARUNA THERAPEUTICS INC | $2,322,000 | – | 10,323 | +100.0% | 0.78% | – |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $2,319,000 | – | 300,000 | +100.0% | 0.78% | – |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $2,240,000 | -41.4% | 10,696 | -34.1% | 0.76% | -35.6% |
| PHR | Buy | PHREESIA INC | $2,123,000 | +8.6% | 83,305 | +6.6% | 0.72% | +19.3% |
| ESPR | New | ESPERION THERAPEUTICS INC NE | $2,104,000 | – | 314,095 | +100.0% | 0.71% | – |
| IMGN | Buy | IMMUNOGEN INC | $2,097,000 | +11.9% | 438,695 | +5.3% | 0.71% | +22.9% |
| ARVN | New | ARVINAS INC | $1,813,000 | – | 40,741 | +100.0% | 0.61% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $1,791,000 | – | 32,011 | +100.0% | 0.61% | – |
| IMVT | New | IMMUNOVANT INC | $1,674,000 | – | 300,000 | +100.0% | 0.57% | – |
| IMTX | Sell | IMMATICS N.V | $1,639,000 | -47.0% | 163,938 | -53.8% | 0.55% | -41.8% |
| BCAB | New | BIOATLA INC | $1,543,000 | – | 200,422 | +100.0% | 0.52% | – |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $1,498,000 | +53.0% | 53,275 | +46.7% | 0.51% | +68.4% |
| SGEN | Sell | SEAGEN INC | $1,454,000 | -79.9% | 10,627 | -73.9% | 0.49% | -77.9% |
| ETNB | New | 89BIO INC | $1,448,000 | – | 250,000 | +100.0% | 0.49% | – |
| TRVI | New | TREVI THERAPEUTICS INC | $1,446,000 | – | 939,265 | +100.0% | 0.49% | – |
| AMYT | Buy | AMRYT PHARMA PLCsponsored ads | $1,303,000 | +5.8% | 188,300 | +6.8% | 0.44% | +16.4% |
| Sell | ELIEM THERAPEUTICS INC | $1,299,000 | -39.7% | 402,088 | -43.6% | 0.44% | -33.8% | |
| ALT | New | ALTIMMUNE INC | $1,283,000 | – | 100,469 | +100.0% | 0.43% | – |
| NGM | Buy | NGM BIOPHARMACEUTICALS INC | $1,236,000 | +9.2% | 94,517 | +7.0% | 0.42% | +19.8% |
| AVXL | New | ANAVEX LIFE SCIENCES CORPcall | $1,032,000 | – | 100,000 | +100.0% | 0.35% | – |
| CDXS | Buy | CODEXIS INC | $881,000 | -38.9% | 145,437 | +5.4% | 0.30% | -32.9% |
| EYPT | Sell | EYEPOINT PHARMACEUTICALS INC | $857,000 | -44.9% | 108,285 | -45.2% | 0.29% | -39.5% |
| New | NUVALENT INC | $806,000 | – | 41,439 | +100.0% | 0.27% | – | |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $714,000 | -70.8% | 10,220 | -71.9% | 0.24% | -67.8% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB L | $627,000 | -89.1% | 10,131 | -86.0% | 0.21% | -88.0% |
| STXS | Sell | STEREOTAXIS INC | $623,000 | -8.1% | 346,231 | -6.1% | 0.21% | +1.0% |
| CMPX | New | COMPASS THERAPEUTICS INC | $598,000 | – | 262,090 | +100.0% | 0.20% | – |
| ASND | New | ASCENDIS PHARMA A/Ssponsored adr | $516,000 | – | 5,000 | +100.0% | 0.18% | – |
| MGTX | Buy | MEIRAGTX HLDGS PLC | $465,000 | +18.0% | 55,342 | +6.3% | 0.16% | +29.8% |
| MGNX | New | MACROGENICS INC | $346,000 | – | 100,000 | +100.0% | 0.12% | – |
| PRTA | New | PROTHENA CORP PLCput | $303,000 | – | 5,000 | +100.0% | 0.10% | – |
| NCNA | New | NUCANA PLCsponsored adr | $282,000 | – | 269,682 | +100.0% | 0.10% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $227,000 | – | 100,000 | +100.0% | 0.08% | – |
| ELOX | Buy | ELOXX PHARMACEUTICALS INC | $187,000 | -33.5% | 1,098,469 | +5.5% | 0.06% | -27.6% |
| EVGN | Sell | EVOGENE LTD | $139,000 | -10.9% | 167,510 | -17.2% | 0.05% | -2.1% |
| TERN | New | TERNS PHARMACEUTICALS INC | $85,000 | – | 14,473 | +100.0% | 0.03% | – |
| PYPD | New | POLYPID LTDput | $59,000 | – | 50,000 | +100.0% | 0.02% | – |
| RENOVACOR INC*w exp 99/99/999 | $8,000 | +33.3% | 104,828 | 0.0% | 0.00% | +50.0% | ||
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $1,000 | -88.9% | 49,990 | 0.0% | 0.00% | -100.0% | |
| ALGS | Exit | ALIGOS THERAPEUTICS INC | $0 | – | -58,392 | -100.0% | -0.02% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -156,195 | -100.0% | -0.05% | – |
| CGEN | Exit | COMPUGEN LTDord | $0 | – | -104,150 | -100.0% | -0.06% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -26,036 | -100.0% | -0.20% | – |
| FMTX | Exit | FORMA THERAPEUTICS HLDGS INC | $0 | – | -94,386 | -100.0% | -0.20% | – |
| PYPD | Exit | POLYPID LTD | $0 | – | -161,572 | -100.0% | -0.23% | – |
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -209,108 | -100.0% | -0.27% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEWput | $0 | – | -36,000 | -100.0% | -0.30% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -208,330 | -100.0% | -0.34% | – |
| HGEN | Exit | HUMANIGEN INCput | $0 | – | -781,100 | -100.0% | -0.43% | – |
| DAWN | Exit | DAY ONE BIOPHARMACEUTICALS I | $0 | – | -105,476 | -100.0% | -0.58% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -107,852 | -100.0% | -0.64% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -1,041,273 | -100.0% | -0.67% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO L | $0 | – | -26,374 | -100.0% | -1.18% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -20,825 | -100.0% | -1.31% | – |
| CFRX | Exit | CONTRAFECT CORPput | $0 | – | -1,562,900 | -100.0% | -1.48% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INCcall | $0 | – | -40,000 | -100.0% | -1.80% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -129,795 | -100.0% | -1.81% | – |
| XBI | Exit | SPDR SER TRcall | $0 | – | -208,300 | -100.0% | -4.76% | – |
| QQQ | Exit | INVESCO QQQ TRput | $0 | – | -162,500 | -100.0% | -14.02% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-10-28
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| INTRA-CELLULAR THERAPIES INC | 12 | Q3 2023 | 7.8% |
| IMMUNOGEN INC | 12 | Q3 2023 | 8.3% |
| Morphic Holding Inc | 12 | Q3 2023 | 4.5% |
| UNUM THERAPEUTICS INC | 12 | Q3 2023 | 3.2% |
| INSMED INC | 12 | Q3 2023 | 3.5% |
| UNITED THERAPEUTICS CORP DEL | 12 | Q3 2023 | 2.2% |
| MERUS N V | 11 | Q3 2023 | 5.1% |
| VERACYTE INC | 11 | Q3 2023 | 4.9% |
| EVOGENE LTD | 11 | Q3 2023 | 1.6% |
| COMPUGEN LTD | 11 | Q3 2023 | 1.1% |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Benitec Biopharma Inc.Sold out | February 08, 2023 | 0 | 0.0% |
| DELCATH SYSTEMS, INC.Sold out | February 08, 2022 | 0 | 0.0% |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2023-11-13 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| 13F-HR | 2023-02-14 |
| SC 13G/A | 2023-02-08 |
| 13F-HR | 2022-10-28 |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.