Q3 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | New | SPRD S&P Biotech ETFcall | $21,906,000 | – | 300,000 | – | 6.64% | – |
| IMGN | Sell | ImmunoGen Incequities | $20,748,993 | -22.6% | 1,307,435 | -7.9% | 6.29% | -24.1% |
| MORF | Buy | Morphic Holding Incequities | $13,535,892 | -6.4% | 590,829 | +134.2% | 4.10% | -8.3% |
| MRUS | Sell | Merus NVequities | $11,790,000 | -24.0% | 500,000 | -15.1% | 3.58% | -25.5% |
| New | Soleno Therapeutics Incequities | $10,918,700 | – | 370,000 | – | 3.31% | – | |
| ITCI | Buy | Intra-Cellular Therapies Incequities | $10,872,746 | -13.6% | 208,730 | +5.0% | 3.30% | -15.3% |
| AKRO | Sell | Akero Therapeutics Inccall | $10,116,000 | -8.4% | 200,000 | -15.4% | 3.07% | -10.2% |
| CBAY | Buy | CymaBay Therapeutics Incequities | $8,796,900 | +402.1% | 590,000 | +268.8% | 2.67% | +392.1% |
| MRTX | Buy | Mirati Therapeutics Incequities | $8,712,000 | +164.4% | 200,000 | +119.3% | 2.64% | +159.2% |
| PSTX | Buy | Poseida Therapeutics Incequities | $8,491,804 | +63.8% | 3,567,985 | +21.1% | 2.58% | +60.5% |
| KRYS | Sell | Krystal Biotech Incequities | $8,297,596 | -40.6% | 71,531 | -39.9% | 2.52% | -41.7% |
| BIIB | Buy | Biogen Idec Incequities | $7,214,014 | -5.7% | 28,069 | +4.5% | 2.19% | -7.6% |
| URGN | New | Urogen Pharma Ltdequities | $7,129,451 | – | 508,883 | – | 2.16% | – |
| UTHR | Buy | United Therapeutics Corpequities | $7,097,739 | +7.1% | 31,424 | +4.6% | 2.15% | +4.9% |
| PRAX | Buy | Praxis Precision Medicines Incequities | $7,041,643 | +76.1% | 4,117,920 | +18.5% | 2.14% | +72.6% |
| ORIC | Sell | Oric Pharmaceuticals Incequities | $6,796,237 | -39.6% | 1,123,345 | -22.6% | 2.06% | -40.8% |
| CRNX | New | Crinetics Pharmaceuticals Incequities | $6,542,800 | – | 220,000 | – | 1.98% | – |
| COGT | Buy | Cogent Biosciences Incequities | $6,350,877 | -13.5% | 651,372 | +5.1% | 1.93% | -15.2% |
| MRSN | Buy | Mersana Therapeutics Incequities | $6,350,000 | +93.0% | 5,000,000 | +400.0% | 1.92% | +89.1% |
| RYTM | Buy | Rhythm Pharmaceuticals Incequities | $5,972,811 | +211.8% | 260,537 | +124.3% | 1.81% | +205.4% |
| MGNX | Buy | MacroGenics Incequities | $5,890,976 | -9.4% | 1,264,158 | +4.0% | 1.79% | -11.2% |
| BCRX | Buy | BioCryst Pharmaceuticals Incequities | $5,605,031 | +4.6% | 791,671 | +4.0% | 1.70% | +2.5% |
| NVO | New | Novo Nordisk A/Sequities | $5,456,400 | – | 60,000 | – | 1.65% | – |
| AKRO | New | Akero Therapeutics Incput | $5,391,828 | – | 106,600 | – | 1.64% | – |
| VCYT | Buy | Veracyte Incequities | $5,349,620 | -8.5% | 239,571 | +4.4% | 1.62% | -10.3% |
| KALV | New | KalVista Pharmaceuticals Inccall | $5,107,752 | – | 530,400 | – | 1.55% | – |
| GOSS | New | Gossamer Bio Incequities | $5,105,287 | – | 6,130,268 | – | 1.55% | – |
| OLMA | Buy | Olema Pharmaceuticals Incequities | $5,036,342 | +42.8% | 407,801 | +4.4% | 1.53% | +40.0% |
| HUM | New | Humana Incequities | $4,865,200 | – | 10,000 | – | 1.48% | – |
| VRTX | Buy | Vertex Pharmaceuticals Incequities | $4,786,641 | +3.2% | 13,765 | +4.5% | 1.45% | +1.2% |
| GILD | Buy | Gilead Sciences Incequities | $4,705,408 | +1.0% | 62,789 | +3.9% | 1.43% | -1.0% |
| PLRX | Buy | Pliant Therapeutics Incequities | $4,342,092 | +123.4% | 250,409 | +133.4% | 1.32% | +119.1% |
| New | Caribou Biosciences Incequities | $4,267,517 | – | 892,786 | – | 1.29% | – | |
| IMGN | New | ImmunoGen Inccall | $3,967,500 | – | 250,000 | – | 1.20% | – |
| TELA | Buy | Tela Bio Incequities | $3,923,768 | -7.0% | 490,471 | +17.8% | 1.19% | -8.8% |
| INSM | Buy | Insmed Incequities | $3,797,272 | +24.6% | 150,387 | +4.1% | 1.15% | +22.1% |
| MIRM | Buy | Mirum Pharmaceuticals Incequities | $3,479,602 | +26.4% | 110,114 | +3.5% | 1.06% | +24.0% |
| CBAY | New | CymaBay Therapeutics Inccall | $2,982,000 | – | 200,000 | – | 0.90% | – |
| RVPH | New | Reviva Pharmaceuticals Holdings Incput | $2,752,320 | – | 564,000 | – | 0.84% | – |
| Buy | Zura Bio Ltdequities | $2,666,664 | +103.3% | 404,040 | +152.5% | 0.81% | +99.3% | |
| TERN | Sell | Terns Pharmaceuticals Incequities | $2,515,000 | -52.1% | 500,000 | -16.6% | 0.76% | -53.0% |
| New | Molecular Templates Incequities | $2,241,123 | – | 354,608 | – | 0.68% | – | |
| KALV | Sell | KalVista Pharmaceuticals Incequities | $2,204,634 | -66.0% | 228,934 | -68.2% | 0.67% | -66.7% |
| TRVI | Buy | Trevi Therapeutics Incequities | $2,021,765 | -4.5% | 927,415 | +4.7% | 0.61% | -6.4% |
| KOD | New | Kodiak Sciences Incequities | $2,006,030 | – | 1,114,461 | – | 0.61% | – |
| CERS | Buy | Cerus Corpequities | $1,950,302 | -31.6% | 1,203,890 | +3.9% | 0.59% | -32.9% |
| XENE | Sell | Xenon Pharmaceuticals Incequities | $1,844,503 | -52.0% | 53,996 | -45.9% | 0.56% | -52.9% |
| EVGN | Buy | Evogene Ltdequities | $1,818,150 | +1599.2% | 3,100,000 | +3000.0% | 0.55% | +1569.7% |
| NTLA | Buy | Intellia Therapeutics Incequities | $1,676,429 | -19.2% | 53,018 | +4.2% | 0.51% | -20.9% |
| AKRO | Sell | Akero Therapeutics Incequities | $1,584,975 | -85.9% | 31,336 | -87.0% | 0.48% | -86.2% |
| ACRS | Sell | Aclaris Therapeutics Inccall | $1,363,150 | -79.8% | 199,000 | -69.5% | 0.41% | -80.2% |
| AVTE | New | Aerovate Therapeutics Incequities | $1,357,000 | – | 100,000 | – | 0.41% | – |
| PRTA | Sell | Prothena Corporation PLCequities | $1,284,849 | -62.2% | 26,629 | -46.4% | 0.39% | -62.9% |
| New | Roivant Sciences Ltdequities | $1,168,000 | – | 100,000 | – | 0.35% | – | |
| ALKS | Buy | Alkermes Plcequities | $1,161,155 | -7.3% | 41,455 | +3.6% | 0.35% | -9.0% |
| SRPT | Sell | Sarepta Therapeutics Incequities | $1,114,860 | -67.4% | 9,197 | -69.2% | 0.34% | -68.1% |
| MRSN | Sell | Mersana Therapeutics Inccall | $1,018,032 | -71.9% | 801,600 | -27.1% | 0.31% | -72.4% |
| ANNX | Buy | Annexon Incequities | $943,330 | -31.3% | 399,716 | +2.5% | 0.29% | -32.7% |
| ETNB | Sell | 89bio Incequities | $930,214 | -87.6% | 60,247 | -84.8% | 0.28% | -87.9% |
| New | Sagimet Biosciences Incequities | $880,000 | – | 100,000 | – | 0.27% | – | |
| SDGR | Sell | Schrodinger Incequities | $856,892 | -94.0% | 30,311 | -89.4% | 0.26% | -94.1% |
| VYGR | Buy | Voyager Therapeutics Incequities | $805,737 | -29.6% | 103,966 | +4.0% | 0.24% | -31.1% |
| KPTI | Buy | Karyopharm Therapeutics Incequities | $753,020 | -18.9% | 561,955 | +8.3% | 0.23% | -20.6% |
| VRDN | Buy | Viridian Therapeutics Incequities | $727,699 | -32.0% | 47,438 | +5.4% | 0.22% | -33.2% |
| RZLT | Sell | Rezolute Incequities | $571,877 | -42.2% | 433,240 | -13.3% | 0.17% | -43.5% |
| CGEN | Buy | Compugen Ltdequities | $325,675 | -13.5% | 350,188 | +6.1% | 0.10% | -14.7% |
| Sell | Eliem Therapeutics Incequities | $318,519 | -77.0% | 121,110 | -75.5% | 0.10% | -77.3% | |
| RLMD | New | Relmada Therapeutics Incequities | $300,000 | – | 100,000 | – | 0.09% | – |
| Sell | Biohaven Ltdequities | $260,100 | -45.6% | 10,000 | -50.0% | 0.08% | -46.6% | |
| CLNN | Buy | Clene Incequities | $247,950 | +12.7% | 500,000 | +100.0% | 0.08% | +10.3% |
| New | Acelyrin Incput | $233,910 | – | 23,000 | – | 0.07% | – | |
| SRRK | New | Scholar Rock Holding Corpequities | $68,948 | – | 9,711 | – | 0.02% | – |
| ACRS | New | Aclaris Therapeutics Incput | $16,440 | – | 2,400 | – | 0.01% | – |
| Exit | Fresh Tracks Therapeutics Incequities | $0 | – | -10,000 | – | -0.00% | – | |
| VRAY | Exit | Viewray Incequities | $0 | – | -100,000 | – | -0.01% | – |
| GKOS | Exit | Glaukos Corpequities | $0 | – | -1,000 | – | -0.02% | – |
| PIRS | Exit | Pieris Pharmaceuticals Incequities | $0 | – | -961,338 | – | -0.05% | – |
| GLUE | Exit | Monte Rosa Therapeutics Incequities | $0 | – | -31,156 | – | -0.07% | – |
| FGEN | Exit | FibroGen Inccall | $0 | – | -100,000 | – | -0.08% | – |
| CLDX | Exit | Celldex Therapeutics Incequities | $0 | – | -10,000 | – | -0.10% | – |
| IMTX | Exit | Immatics Nvequities | $0 | – | -30,715 | – | -0.11% | – |
| Exit | Jasper Therapeutics Incequities | $0 | – | -500,000 | – | -0.21% | – | |
| PTGX | Exit | Protagonist Therapeutics Incequities | $0 | – | -25,000 | – | -0.21% | – |
| Exit | Ventyx Biosciences Incequities | $0 | – | -25,000 | – | -0.25% | – | |
| BBIO | Exit | Bridgebio Pharma Incequities | $0 | – | -50,000 | – | -0.27% | – |
| ALLK | Exit | Allakos Incequities | $0 | – | -200,000 | – | -0.27% | – |
| RETA | Exit | Reata Pharmaceuticals Incequities | $0 | – | -12,500 | – | -0.39% | – |
| CUE | Exit | Cue Biopharma Incequities | $0 | – | -403,402 | – | -0.46% | – |
| AMAM | Exit | Ambrx Biopharma Incequities | $0 | – | -100,000 | – | -0.51% | – |
| INCY | Exit | Incyte Corpequities | $0 | – | -34,110 | – | -0.66% | – |
| ACRS | Exit | Aclaris Therapeutics Incequities | $0 | – | -219,229 | – | -0.70% | – |
| PHAT | Exit | Phathom Pharmaceuticals Incequities | $0 | – | -200,000 | – | -0.89% | – |
| ANIP | Exit | ANI Pharmaceuticals Incequities | $0 | – | -54,041 | – | -0.90% | – |
| PHVS | Exit | Pharvaris NVequities | $0 | – | -200,000 | – | -0.94% | – |
| VKTX | Exit | Viking Therapeutics Incequities | $0 | – | -258,595 | – | -1.30% | – |
| Exit | Nuvalent Incequities | $0 | – | -115,067 | – | -1.50% | – | |
| Exit | MoonLake Immunotherapeuticsequities | $0 | – | -200,000 | – | -3.16% | – |
Q2 2023
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IMGN | New | ImmunoGen Incequities | $26,795,400 | – | 1,420,000 | – | 8.29% | – |
| MRUS | New | Merus NVequities | $15,515,084 | – | 589,255 | – | 4.80% | – |
| MORF | New | Morphic Holding Incequities | $14,464,875 | – | 252,309 | – | 4.47% | – |
| SDGR | New | Schrodinger Incequities | $14,285,556 | – | 286,169 | – | 4.42% | – |
| KRYS | New | Krystal Biotech Incequities | $13,963,673 | – | 118,941 | – | 4.32% | – |
| ITCI | New | Intra-Cellular Therapies Incequities | $12,583,140 | – | 198,723 | – | 3.89% | – |
| AKRO | New | Akero Therapeutics Incequities | $11,268,958 | – | 241,357 | – | 3.49% | – |
| ORIC | New | Oric Pharmaceuticals Incequities | $11,258,379 | – | 1,450,822 | – | 3.48% | – |
| AKRO | New | Akero Therapeutics Inccall | $11,039,820 | – | 236,500 | – | 3.42% | – |
| New | MoonLake Immunotherapeuticsequities | $10,200,000 | – | 200,000 | – | 3.16% | – | |
| BIIB | New | Biogen Idec Incequities | $7,649,362 | – | 26,854 | – | 2.37% | – |
| ETNB | New | 89bio Incequities | $7,513,618 | – | 396,497 | – | 2.32% | – |
| COGT | New | Cogent Biosciences Incequities | $7,340,800 | – | 620,000 | – | 2.27% | – |
| ACRS | New | Aclaris Therapeutics Inccall | $6,755,018 | – | 651,400 | – | 2.09% | – |
| UTHR | New | United Therapeutics Corpequities | $6,628,902 | – | 30,029 | – | 2.05% | – |
| MGNX | New | MacroGenics Incequities | $6,503,861 | – | 1,215,675 | – | 2.01% | – |
| KALV | New | KalVista Pharmaceuticals Incequities | $6,484,572 | – | 720,508 | – | 2.01% | – |
| VCYT | New | Veracyte Incequities | $5,844,117 | – | 229,451 | – | 1.81% | – |
| MRTX | New | Mirati Therapeutics Inccall | $5,419,500 | – | 150,000 | – | 1.68% | – |
| BCRX | New | BioCryst Pharmaceuticals Incequities | $5,356,764 | – | 760,904 | – | 1.66% | – |
| TERN | New | Terns Pharmaceuticals Incequities | $5,247,095 | – | 599,668 | – | 1.62% | – |
| PSTX | New | Poseida Therapeutics Incequities | $5,184,868 | – | 2,945,948 | – | 1.60% | – |
| New | Nuvalent Incequities | $4,852,375 | – | 115,067 | – | 1.50% | – | |
| GILD | New | Gilead Sciences Incequities | $4,658,727 | – | 60,448 | – | 1.44% | – |
| VRTX | New | Vertex Pharmaceuticals Incequities | $4,636,414 | – | 13,175 | – | 1.43% | – |
| TELA | New | Tela Bio Incequities | $4,218,537 | – | 416,440 | – | 1.30% | – |
| VKTX | New | Viking Therapeutics Incequities | $4,191,825 | – | 258,595 | – | 1.30% | – |
| PRAX | New | Praxis Precision Medicines Incequities | $3,997,586 | – | 3,476,162 | – | 1.24% | – |
| XENE | New | Xenon Pharmaceuticals Incequities | $3,840,606 | – | 99,756 | – | 1.19% | – |
| MRSN | New | Mersana Therapeutics Inccall | $3,619,000 | – | 1,100,000 | – | 1.12% | – |
| OLMA | New | Olema Pharmaceuticals Incequities | $3,525,908 | – | 390,466 | – | 1.09% | – |
| SRPT | New | Sarepta Therapeutics Incequities | $3,419,567 | – | 29,860 | – | 1.06% | – |
| PRTA | New | Prothena Corporation PLCequities | $3,394,950 | – | 49,721 | – | 1.05% | – |
| MRTX | New | Mirati Therapeutics Incequities | $3,295,526 | – | 91,213 | – | 1.02% | – |
| MRSN | New | Mersana Therapeutics Incequities | $3,290,000 | – | 1,000,000 | – | 1.02% | – |
| INSM | New | Insmed Incequities | $3,048,190 | – | 144,464 | – | 0.94% | – |
| PHVS | New | Pharvaris NVequities | $3,028,000 | – | 200,000 | – | 0.94% | – |
| ANIP | New | ANI Pharmaceuticals Incequities | $2,909,027 | – | 54,041 | – | 0.90% | – |
| PHAT | New | Phathom Pharmaceuticals Incequities | $2,864,000 | – | 200,000 | – | 0.89% | – |
| CERS | New | Cerus Corpequities | $2,849,332 | – | 1,158,265 | – | 0.88% | – |
| MIRM | New | Mirum Pharmaceuticals Incequities | $2,751,921 | – | 106,375 | – | 0.85% | – |
| ACRS | New | Aclaris Therapeutics Incequities | $2,273,405 | – | 219,229 | – | 0.70% | – |
| INCY | New | Incyte Corpequities | $2,123,348 | – | 34,110 | – | 0.66% | – |
| TRVI | New | Trevi Therapeutics Incequities | $2,117,358 | – | 885,924 | – | 0.66% | – |
| NTLA | New | Intellia Therapeutics Incequities | $2,073,989 | – | 50,858 | – | 0.64% | – |
| PLRX | New | Pliant Therapeutics Incequities | $1,943,678 | – | 107,267 | – | 0.60% | – |
| RYTM | New | Rhythm Pharmaceuticals Incequities | $1,915,610 | – | 116,168 | – | 0.59% | – |
| CBAY | New | CymaBay Therapeutics Incequities | $1,752,000 | – | 160,000 | – | 0.54% | – |
| AMAM | New | Ambrx Biopharma Incequities | $1,646,000 | – | 100,000 | – | 0.51% | – |
| CUE | New | Cue Biopharma Incequities | $1,472,417 | – | 403,402 | – | 0.46% | – |
| New | Eliem Therapeutics Incequities | $1,383,449 | – | 494,089 | – | 0.43% | – | |
| ANNX | New | Annexon Incequities | $1,372,487 | – | 389,911 | – | 0.42% | – |
| New | Zura Bio Ltdequities | $1,312,000 | – | 160,000 | – | 0.41% | – | |
| RETA | New | Reata Pharmaceuticals Incequities | $1,274,500 | – | 12,500 | – | 0.39% | – |
| ALKS | New | Alkermes Plcequities | $1,252,000 | – | 40,000 | – | 0.39% | – |
| VYGR | New | Voyager Therapeutics Incequities | $1,145,000 | – | 100,000 | – | 0.35% | – |
| VRDN | New | Viridian Therapeutics Incequities | $1,070,550 | – | 45,000 | – | 0.33% | – |
| RZLT | New | Rezolute Incequities | $989,097 | – | 499,544 | – | 0.31% | – |
| KPTI | New | Karyopharm Therapeutics Incequities | $928,983 | – | 518,985 | – | 0.29% | – |
| ALLK | New | Allakos Incequities | $872,000 | – | 200,000 | – | 0.27% | – |
| BMRN | New | BioMarin Pharmaceutical Incequities | $866,800 | – | 10,000 | – | 0.27% | – |
| BBIO | New | Bridgebio Pharma Incequities | $860,000 | – | 50,000 | – | 0.27% | – |
| PNT | New | Point Biopharma Global Incequities | $848,922 | – | 93,700 | – | 0.26% | – |
| New | Ventyx Biosciences Incequities | $820,000 | – | 25,000 | – | 0.25% | – | |
| PTGX | New | Protagonist Therapeutics Incequities | $690,500 | – | 25,000 | – | 0.21% | – |
| New | Jasper Therapeutics Incequities | $685,000 | – | 500,000 | – | 0.21% | – | |
| ALGS | New | Aligos Therapeutics Incequities | $613,562 | – | 631,887 | – | 0.19% | – |
| New | Biohaven Ltdequities | $478,400 | – | 20,000 | – | 0.15% | – | |
| SNDX | New | Syndax Pharmaceuticals Incequities | $418,600 | – | 20,000 | – | 0.13% | – |
| CGEN | New | Compugen Ltdequities | $376,414 | – | 330,188 | – | 0.12% | – |
| IMTX | New | Immatics Nvequities | $354,451 | – | 30,715 | – | 0.11% | – |
| CLDX | New | Celldex Therapeutics Incequities | $339,300 | – | 10,000 | – | 0.10% | – |
| FGEN | New | FibroGen Inccall | $271,000 | – | 100,000 | – | 0.08% | – |
| CLNN | New | Clene Incequities | $219,975 | – | 250,000 | – | 0.07% | – |
| GLUE | New | Monte Rosa Therapeutics Incequities | $213,419 | – | 31,156 | – | 0.07% | – |
| New | Eloxx Pharmaceuticals Incequities | $210,352 | – | 54,075 | – | 0.06% | – | |
| PIRS | New | Pieris Pharmaceuticals Incequities | $159,101 | – | 961,338 | – | 0.05% | – |
| EVGN | New | Evogene Ltdequities | $107,000 | – | 100,000 | – | 0.03% | – |
| GKOS | New | Glaukos Corpequities | $71,210 | – | 1,000 | – | 0.02% | – |
| VRAY | New | Viewray Incequities | $35,220 | – | 100,000 | – | 0.01% | – |
| New | Rocket Pharmaceuticals Incwarrants | $19,917 | – | 104,828 | – | 0.01% | – | |
| New | Fresh Tracks Therapeutics Incequities | $7,013 | – | 10,000 | – | 0.00% | – |
Q4 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MSACW | Exit | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $0 | – | -49,990 | – | 0.00% | – |
| Exit | RENOVACOR INC*w exp 99/99/999 | $0 | – | -104,828 | – | -0.00% | – | |
| PYPD | Exit | POLYPID LTDput | $0 | – | -50,000 | – | -0.02% | – |
| TERN | Exit | TERNS PHARMACEUTICALS INC | $0 | – | -14,473 | – | -0.03% | – |
| EVGN | Exit | EVOGENE LTD | $0 | – | -167,510 | – | -0.05% | – |
| ELOX | Exit | ELOXX PHARMACEUTICALS INC | $0 | – | -1,098,469 | – | -0.06% | – |
| PRAX | Exit | PRAXIS PRECISION MEDICINES I | $0 | – | -100,000 | – | -0.08% | – |
| NCNA | Exit | NUCANA PLCsponsored adr | $0 | – | -269,682 | – | -0.10% | – |
| PRTA | Exit | PROTHENA CORP PLCput | $0 | – | -5,000 | – | -0.10% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -100,000 | – | -0.12% | – |
| MGTX | Exit | MEIRAGTX HLDGS PLC | $0 | – | -55,342 | – | -0.16% | – |
| ASND | Exit | ASCENDIS PHARMA A/Ssponsored adr | $0 | – | -5,000 | – | -0.18% | – |
| CMPX | Exit | COMPASS THERAPEUTICS INC | $0 | – | -262,090 | – | -0.20% | – |
| STXS | Exit | STEREOTAXIS INC | $0 | – | -346,231 | – | -0.21% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -10,131 | – | -0.21% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -10,220 | – | -0.24% | – |
| Exit | NUVALENT INC | $0 | – | -41,439 | – | -0.27% | – | |
| EYPT | Exit | EYEPOINT PHARMACEUTICALS INC | $0 | – | -108,285 | – | -0.29% | – |
| CDXS | Exit | CODEXIS INC | $0 | – | -145,437 | – | -0.30% | – |
| AVXL | Exit | ANAVEX LIFE SCIENCES CORPcall | $0 | – | -100,000 | – | -0.35% | – |
| NGM | Exit | NGM BIOPHARMACEUTICALS INC | $0 | – | -94,517 | – | -0.42% | – |
| ALT | Exit | ALTIMMUNE INC | $0 | – | -100,469 | – | -0.43% | – |
| Exit | ELIEM THERAPEUTICS INC | $0 | – | -402,088 | – | -0.44% | – | |
| AMYT | Exit | AMRYT PHARMA PLCsponsored ads | $0 | – | -188,300 | – | -0.44% | – |
| TRVI | Exit | TREVI THERAPEUTICS INC | $0 | – | -939,265 | – | -0.49% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -250,000 | – | -0.49% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -10,627 | – | -0.49% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -53,275 | – | -0.51% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -200,422 | – | -0.52% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -163,938 | – | -0.55% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -300,000 | – | -0.57% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -32,011 | – | -0.61% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -40,741 | – | -0.61% | – |
| IMGN | Exit | IMMUNOGEN INC | $0 | – | -438,695 | – | -0.71% | – |
| ESPR | Exit | ESPERION THERAPEUTICS INC NE | $0 | – | -314,095 | – | -0.71% | – |
| PHR | Exit | PHREESIA INC | $0 | – | -83,305 | – | -0.72% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -10,696 | – | -0.76% | – |
| PNT | Exit | POINT BIOPHARMA GLOBAL INC | $0 | – | -300,000 | – | -0.78% | – |
| KRTX | Exit | KARUNA THERAPEUTICS INC | $0 | – | -10,323 | – | -0.78% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS INC | $0 | – | -186,603 | – | -0.80% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -366,493 | – | -0.80% | – |
| ALLK | Exit | ALLAKOS INC | $0 | – | -400,000 | – | -0.83% | – |
| LVTX | Exit | LAVA THERAPEUTICS NV | $0 | – | -610,809 | – | -0.94% | – |
| CVRX | Exit | CVRX INC | $0 | – | -307,920 | – | -0.97% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -224,555 | – | -0.97% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -110,085 | – | -0.98% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -149,027 | – | -0.99% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCcall | $0 | – | -42,500 | – | -1.00% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -177,364 | – | -1.08% | – |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -11,105 | – | -1.09% | – |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -1,208,992 | – | -1.31% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -56,645 | – | -1.34% | – |
| ABOS | Exit | ACUMEN PHARMACEUTICALS INC | $0 | – | -420,000 | – | -1.42% | – |
| PLRX | Exit | PLIANT THERAPEUTICS INC | $0 | – | -209,822 | – | -1.48% | – |
| NKTX | Exit | NKARTA INC | $0 | – | -362,377 | – | -1.61% | – |
| INSM | Exit | INSMED INC | $0 | – | -224,016 | – | -1.63% | – |
| CLNN | Exit | CLENE INCput | $0 | – | -1,734,800 | – | -1.64% | – |
| CTIC | Exit | CTI BIOPHARMA CORP | $0 | – | -983,516 | – | -1.94% | – |
| CERS | Exit | CERUS CORP | $0 | – | -1,616,459 | – | -1.97% | – |
| MRUS | Exit | MERUS N V | $0 | – | -295,136 | – | -2.00% | – |
| APEN | Exit | APOLLO ENDOSURGERY INC | $0 | – | -1,136,206 | – | -2.12% | – |
| ITCI | Exit | INTRA-CELLULAR THERAPIES INC | $0 | – | -136,126 | – | -2.14% | – |
| VERU | Exit | VERU INCput | $0 | – | -550,000 | – | -2.14% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -32,545 | – | -2.20% | – |
| PRTA | Exit | PROTHENA CORP PLC | $0 | – | -110,000 | – | -2.26% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -994,073 | – | -2.27% | – |
| ISEE | Exit | IVERIC BIO INCput | $0 | – | -443,100 | – | -2.69% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -2,324,066 | – | -2.86% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -543,776 | – | -2.90% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -245,992 | – | -3.00% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -2,554,277 | – | -3.05% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -606,608 | – | -3.06% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -324,421 | – | -3.10% | – |
| AVXL | Exit | ANAVEX LIFE SCIENCES CORPput | $0 | – | -942,500 | – | -3.29% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -300,000 | – | -3.46% | – |
| VCYT | Exit | VERACYTE INC | $0 | – | -665,854 | – | -3.74% | – |
| RXDX | Exit | PROMETHEUS BIOSCIENCES INCput | $0 | – | -204,700 | – | -4.09% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INCput | $0 | – | -393,000 | – | -4.92% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -1,655,775 | – | -5.91% | – |
Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BLU | Buy | BELLUS HEALTH INC NEW | $17,485,000 | +21.1% | 1,655,775 | +5.9% | 5.91% | +33.0% |
| RLMD | New | RELMADA THERAPEUTICS INCput | $14,549,000 | – | 393,000 | – | 4.92% | – |
| RXDX | Sell | PROMETHEUS BIOSCIENCES INCput | $12,079,000 | +41.8% | 204,700 | -32.2% | 4.09% | +55.8% |
| VCYT | Sell | VERACYTE INC | $11,053,000 | -22.7% | 665,854 | -7.4% | 3.74% | -15.1% |
| AKRO | Buy | AKERO THERAPEUTICS INC | $10,215,000 | +315.2% | 300,000 | +15.2% | 3.46% | +356.4% |
| AVXL | Buy | ANAVEX LIFE SCIENCES CORPput | $9,727,000 | +6.0% | 942,500 | +2.8% | 3.29% | +16.4% |
| MORF | Sell | MORPHIC HLDG INC | $9,181,000 | +1.1% | 324,421 | -22.5% | 3.10% | +11.0% |
| COGT | Sell | COGENT BIOSCIENCES INC | $9,051,000 | +22.2% | 606,608 | -26.1% | 3.06% | +34.3% |
| PSTX | Buy | POSEIDA THERAPEUTICS INC | $9,017,000 | +818.2% | 2,554,277 | +571.1% | 3.05% | +909.9% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $8,880,000 | +25.5% | 245,992 | +5.7% | 3.00% | +37.9% |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $8,559,000 | +13.6% | 543,776 | +0.8% | 2.90% | +24.8% |
| VRAY | Buy | VIEWRAY INC | $8,460,000 | +335.6% | 2,324,066 | +217.2% | 2.86% | +378.6% |
| ISEE | Buy | IVERIC BIO INCput | $7,949,000 | +91.8% | 443,100 | +2.8% | 2.69% | +110.7% |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $6,720,000 | +71.1% | 994,073 | +16.9% | 2.27% | +88.0% |
| PRTA | New | PROTHENA CORP PLC | $6,669,000 | – | 110,000 | – | 2.26% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $6,514,000 | – | 32,545 | – | 2.20% | – |
| VERU | Sell | VERU INCput | $6,336,000 | -28.2% | 550,000 | -29.5% | 2.14% | -21.1% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES INC | $6,334,000 | -64.7% | 136,126 | -56.6% | 2.14% | -61.2% |
| APEN | Buy | APOLLO ENDOSURGERY INC | $6,260,000 | +59.6% | 1,136,206 | +5.7% | 2.12% | +75.2% |
| MRUS | Sell | MERUS N V | $5,912,000 | -44.3% | 295,136 | -37.1% | 2.00% | -38.8% |
| CERS | Sell | CERUS CORP | $5,819,000 | -47.5% | 1,616,459 | -22.8% | 1.97% | -42.3% |
| CTIC | Sell | CTI BIOPHARMA CORP | $5,724,000 | -30.5% | 983,516 | -28.7% | 1.94% | -23.7% |
| CLNN | New | CLENE INCput | $4,857,000 | – | 1,734,800 | – | 1.64% | – |
| INSM | Buy | INSMED INC | $4,825,000 | +15.2% | 224,016 | +5.4% | 1.63% | +26.5% |
| NKTX | Buy | NKARTA INC | $4,769,000 | +249.4% | 362,377 | +227.2% | 1.61% | +284.0% |
| PLRX | New | PLIANT THERAPEUTICS INC | $4,383,000 | – | 209,822 | – | 1.48% | – |
| ABOS | New | ACUMEN PHARMACEUTICALS INC | $4,213,000 | – | 420,000 | – | 1.42% | – |
| KRYS | Sell | KRYSTAL BIOTECH INC | $3,948,000 | -42.9% | 56,645 | -46.2% | 1.34% | -37.3% |
| ORIC | Buy | ORIC PHARMACEUTICALS INC | $3,869,000 | -20.2% | 1,208,992 | +11.7% | 1.31% | -12.3% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $3,215,000 | +9.5% | 11,105 | +6.6% | 1.09% | +20.2% |
| ISEE | New | IVERIC BIO INC | $3,182,000 | – | 177,364 | – | 1.08% | – |
| MRTX | Sell | MIRATI THERAPEUTICS INCcall | $2,968,000 | -56.2% | 42,500 | -57.9% | 1.00% | -51.8% |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $2,927,000 | +12.5% | 149,027 | +6.8% | 0.99% | +23.6% |
| RGNX | Buy | REGENXBIO INC | $2,910,000 | +13.1% | 110,085 | +5.7% | 0.98% | +24.2% |
| CGEM | Buy | CULLINAN ONCOLOGY INC | $2,879,000 | +5.4% | 224,555 | +5.4% | 0.97% | +15.8% |
| CVRX | Buy | CVRX INC | $2,873,000 | +63.6% | 307,920 | +5.4% | 0.97% | +79.7% |
| LVTX | New | LAVA THERAPEUTICS NV | $2,791,000 | – | 610,809 | – | 0.94% | – |
| ALLK | New | ALLAKOS INC | $2,448,000 | – | 400,000 | – | 0.83% | – |
| MCRB | Buy | SERES THERAPEUTICS INC | $2,353,000 | +97.2% | 366,493 | +5.4% | 0.80% | +116.9% |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $2,351,000 | +315.4% | 186,603 | +248.7% | 0.80% | +356.9% |
| KRTX | New | KARUNA THERAPEUTICS INC | $2,322,000 | – | 10,323 | – | 0.78% | – |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $2,319,000 | – | 300,000 | – | 0.78% | – |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $2,240,000 | -41.4% | 10,696 | -34.1% | 0.76% | -35.6% |
| PHR | Buy | PHREESIA INC | $2,123,000 | +8.6% | 83,305 | +6.6% | 0.72% | +19.3% |
| ESPR | New | ESPERION THERAPEUTICS INC NE | $2,104,000 | – | 314,095 | – | 0.71% | – |
| IMGN | Buy | IMMUNOGEN INC | $2,097,000 | +11.9% | 438,695 | +5.3% | 0.71% | +22.9% |
| ARVN | New | ARVINAS INC | $1,813,000 | – | 40,741 | – | 0.61% | – |
| NTLA | New | INTELLIA THERAPEUTICS INC | $1,791,000 | – | 32,011 | – | 0.61% | – |
| IMVT | New | IMMUNOVANT INC | $1,674,000 | – | 300,000 | – | 0.57% | – |
| IMTX | Sell | IMMATICS N.V | $1,639,000 | -47.0% | 163,938 | -53.8% | 0.55% | -41.8% |
| BCAB | New | BIOATLA INC | $1,543,000 | – | 200,422 | – | 0.52% | – |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $1,498,000 | +53.0% | 53,275 | +46.7% | 0.51% | +68.4% |
| SGEN | Sell | SEAGEN INC | $1,454,000 | -79.9% | 10,627 | -73.9% | 0.49% | -77.9% |
| ETNB | New | 89BIO INC | $1,448,000 | – | 250,000 | – | 0.49% | – |
| TRVI | New | TREVI THERAPEUTICS INC | $1,446,000 | – | 939,265 | – | 0.49% | – |
| AMYT | Buy | AMRYT PHARMA PLCsponsored ads | $1,303,000 | +5.8% | 188,300 | +6.8% | 0.44% | +16.4% |
| Sell | ELIEM THERAPEUTICS INC | $1,299,000 | -39.7% | 402,088 | -43.6% | 0.44% | -33.8% | |
| ALT | New | ALTIMMUNE INC | $1,283,000 | – | 100,469 | – | 0.43% | – |
| NGM | Buy | NGM BIOPHARMACEUTICALS INC | $1,236,000 | +9.2% | 94,517 | +7.0% | 0.42% | +19.8% |
| AVXL | New | ANAVEX LIFE SCIENCES CORPcall | $1,032,000 | – | 100,000 | – | 0.35% | – |
| CDXS | Buy | CODEXIS INC | $881,000 | -38.9% | 145,437 | +5.4% | 0.30% | -32.9% |
| EYPT | Sell | EYEPOINT PHARMACEUTICALS INC | $857,000 | -44.9% | 108,285 | -45.2% | 0.29% | -39.5% |
| New | NUVALENT INC | $806,000 | – | 41,439 | – | 0.27% | – | |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $714,000 | -70.8% | 10,220 | -71.9% | 0.24% | -67.8% |
| HZNP | Sell | HORIZON THERAPEUTICS PUB L | $627,000 | -89.1% | 10,131 | -86.0% | 0.21% | -88.0% |
| STXS | Sell | STEREOTAXIS INC | $623,000 | -8.1% | 346,231 | -6.1% | 0.21% | +1.0% |
| CMPX | New | COMPASS THERAPEUTICS INC | $598,000 | – | 262,090 | – | 0.20% | – |
| ASND | New | ASCENDIS PHARMA A/Ssponsored adr | $516,000 | – | 5,000 | – | 0.18% | – |
| MGTX | Buy | MEIRAGTX HLDGS PLC | $465,000 | +18.0% | 55,342 | +6.3% | 0.16% | +29.8% |
| MGNX | New | MACROGENICS INC | $346,000 | – | 100,000 | – | 0.12% | – |
| PRTA | New | PROTHENA CORP PLCput | $303,000 | – | 5,000 | – | 0.10% | – |
| NCNA | New | NUCANA PLCsponsored adr | $282,000 | – | 269,682 | – | 0.10% | – |
| PRAX | New | PRAXIS PRECISION MEDICINES I | $227,000 | – | 100,000 | – | 0.08% | – |
| ELOX | Buy | ELOXX PHARMACEUTICALS INC | $187,000 | -33.5% | 1,098,469 | +5.5% | 0.06% | -27.6% |
| EVGN | Sell | EVOGENE LTD | $139,000 | -10.9% | 167,510 | -17.2% | 0.05% | -2.1% |
| TERN | New | TERNS PHARMACEUTICALS INC | $85,000 | – | 14,473 | – | 0.03% | – |
| PYPD | New | POLYPID LTDput | $59,000 | – | 50,000 | – | 0.02% | – |
| ALGS | Exit | ALIGOS THERAPEUTICS INC | $0 | – | -58,392 | – | -0.02% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -156,195 | – | -0.05% | – |
| CGEN | Exit | COMPUGEN LTDord | $0 | – | -104,150 | – | -0.06% | – |
| CCXI | Exit | CHEMOCENTRYX INC | $0 | – | -26,036 | – | -0.20% | – |
| FMTX | Exit | FORMA THERAPEUTICS HLDGS INC | $0 | – | -94,386 | – | -0.20% | – |
| PYPD | Exit | POLYPID LTD | $0 | – | -161,572 | – | -0.23% | – |
| SBTX | Exit | SILVERBACK THERAPEUTICS INC | $0 | – | -209,108 | – | -0.27% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEWput | $0 | – | -36,000 | – | -0.30% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -208,330 | – | -0.34% | – |
| HGEN | Exit | HUMANIGEN INCput | $0 | – | -781,100 | – | -0.43% | – |
| DAWN | Exit | DAY ONE BIOPHARMACEUTICALS I | $0 | – | -105,476 | – | -0.58% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -107,852 | – | -0.64% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -1,041,273 | – | -0.67% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO L | $0 | – | -26,374 | – | -1.18% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -20,825 | – | -1.31% | – |
| CFRX | Exit | CONTRAFECT CORPput | $0 | – | -1,562,900 | – | -1.48% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INCcall | $0 | – | -40,000 | – | -1.80% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -129,795 | – | -1.81% | – |
| XBI | Exit | SPDR SER TRcall | $0 | – | -208,300 | – | -4.76% | – |
| QQQ | Exit | INVESCO QQQ TRput | $0 | – | -162,500 | – | -14.02% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| QQQ | New | INVESCO QQQ TRput | $45,546,000 | – | 162,500 | – | 14.02% | – |
| ITCI | New | INTRA-CELLULAR THERAPIES INC | $17,921,000 | – | 313,962 | – | 5.52% | – |
| XBI | New | SPDR SER TRcall | $15,470,000 | – | 208,300 | – | 4.76% | – |
| BLU | New | BELLUS HEALTH INC NEW | $14,442,000 | – | 1,562,957 | – | 4.45% | – |
| VCYT | New | VERACYTE INC | $14,304,000 | – | 718,789 | – | 4.40% | – |
| CERS | New | CERUS CORP | $11,077,000 | – | 2,093,861 | – | 3.41% | – |
| MRUS | New | MERUS N V | $10,621,000 | – | 469,113 | – | 3.27% | – |
| AVXL | New | ANAVEX LIFE SCIENCES CORPput | $9,180,000 | – | 917,100 | – | 2.83% | – |
| MORF | New | MORPHIC HLDG INC | $9,085,000 | – | 418,660 | – | 2.80% | – |
| VERU | New | VERU INCput | $8,819,000 | – | 780,400 | – | 2.72% | – |
| RXDX | New | PROMETHEUS BIOSCIENCES INCput | $8,517,000 | – | 301,700 | – | 2.62% | – |
| CTIC | New | CTI BIOPHARMA CORP | $8,239,000 | – | 1,380,111 | – | 2.54% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $7,532,000 | – | 539,545 | – | 2.32% | – |
| COGT | New | COGENT BIOSCIENCES INC | $7,405,000 | – | 820,954 | – | 2.28% | – |
| SGEN | New | SEAGEN INC | $7,217,000 | – | 40,787 | – | 2.22% | – |
| XENE | New | XENON PHARMACEUTICALS INC | $7,077,000 | – | 232,630 | – | 2.18% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $6,912,000 | – | 105,277 | – | 2.13% | – |
| MRTX | New | MIRATI THERAPEUTICS INCcall | $6,773,000 | – | 100,900 | – | 2.08% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $5,869,000 | – | 129,795 | – | 1.81% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INCcall | $5,834,000 | – | 40,000 | – | 1.80% | – |
| HZNP | New | HORIZON THERAPEUTICS PUB L | $5,758,000 | – | 72,187 | – | 1.77% | – |
| ORIC | New | ORIC PHARMACEUTICALS INC | $4,849,000 | – | 1,082,304 | – | 1.49% | – |
| CFRX | New | CONTRAFECT CORPput | $4,798,000 | – | 1,562,900 | – | 1.48% | – |
| BIIB | New | BIOGEN INC | $4,247,000 | – | 20,825 | – | 1.31% | – |
| INSM | New | INSMED INC | $4,190,000 | – | 212,482 | – | 1.29% | – |
| ISEE | New | IVERIC BIO INCput | $4,145,000 | – | 430,900 | – | 1.28% | – |
| MRSN | New | MERSANA THERAPEUTICS INC | $3,927,000 | – | 850,000 | – | 1.21% | – |
| APEN | New | APOLLO ENDOSURGERY INC | $3,923,000 | – | 1,074,879 | – | 1.21% | – |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $3,843,000 | – | 26,374 | – | 1.18% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $3,824,000 | – | 16,227 | – | 1.18% | – |
| IMTX | New | IMMATICS N.V | $3,093,000 | – | 355,103 | – | 0.95% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $2,935,000 | – | 10,414 | – | 0.90% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $2,732,000 | – | 213,090 | – | 0.84% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $2,602,000 | – | 139,539 | – | 0.80% | – |
| RGNX | New | REGENXBIO INC | $2,572,000 | – | 104,129 | – | 0.79% | – |
| AKRO | New | AKERO THERAPEUTICS INC | $2,460,000 | – | 260,325 | – | 0.76% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $2,444,000 | – | 36,403 | – | 0.75% | – |
| OTIC | New | OTONOMY INC | $2,166,000 | – | 1,041,273 | – | 0.67% | – |
| New | ELIEM THERAPEUTICS INC | $2,153,000 | – | 713,009 | – | 0.66% | – | |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $2,075,000 | – | 107,852 | – | 0.64% | – |
| PHR | New | PHREESIA INC | $1,954,000 | – | 78,111 | – | 0.60% | – |
| VRAY | New | VIEWRAY INC | $1,942,000 | – | 732,740 | – | 0.60% | – |
| DAWN | New | DAY ONE BIOPHARMACEUTICALS I | $1,888,000 | – | 105,476 | – | 0.58% | – |
| IMGN | New | IMMUNOGEN INC | $1,874,000 | – | 416,479 | – | 0.58% | – |
| CVRX | New | CVRX INC | $1,756,000 | – | 292,145 | – | 0.54% | – |
| EYPT | New | EYEPOINT PHARMACEUTICALS INC | $1,555,000 | – | 197,640 | – | 0.48% | – |
| CDXS | New | CODEXIS INC | $1,443,000 | – | 137,960 | – | 0.44% | – |
| HGEN | New | HUMANIGEN INCput | $1,383,000 | – | 781,100 | – | 0.43% | – |
| NKTX | New | NKARTA INC | $1,365,000 | – | 110,763 | – | 0.42% | – |
| AMYT | New | AMRYT PHARMA PLCsponsored ads | $1,232,000 | – | 176,309 | – | 0.38% | – |
| MCRB | New | SERES THERAPEUTICS INC | $1,193,000 | – | 347,761 | – | 0.37% | – |
| NGM | New | NGM BIOPHARMACEUTICALS INC | $1,132,000 | – | 88,303 | – | 0.35% | – |
| ZYME | New | ZYMEWORKS INC | $1,104,000 | – | 208,330 | – | 0.34% | – |
| PSTX | New | POSEIDA THERAPEUTICS INC | $982,000 | – | 380,606 | – | 0.30% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $979,000 | – | 36,322 | – | 0.30% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEWput | $971,000 | – | 36,000 | – | 0.30% | – |
| SBTX | New | SILVERBACK THERAPEUTICS INC | $887,000 | – | 209,108 | – | 0.27% | – |
| PYPD | New | POLYPID LTD | $750,000 | – | 161,572 | – | 0.23% | – |
| STXS | New | STEREOTAXIS INC | $678,000 | – | 368,648 | – | 0.21% | – |
| FMTX | New | FORMA THERAPEUTICS HLDGS INC | $650,000 | – | 94,386 | – | 0.20% | – |
| CCXI | New | CHEMOCENTRYX INC | $645,000 | – | 26,036 | – | 0.20% | – |
| BCRX | New | BIOCRYST PHARMACEUTICALS INC | $566,000 | – | 53,521 | – | 0.17% | – |
| MGTX | New | MEIRAGTX HLDGS PLC | $394,000 | – | 52,066 | – | 0.12% | – |
| ELOX | New | ELOXX PHARMACEUTICALS INC | $281,000 | – | 1,041,499 | – | 0.09% | – |
| CGEN | New | COMPUGEN LTDord | $193,000 | – | 104,150 | – | 0.06% | – |
| MREO | New | MEREO BIOPHARMA GROUP PLCads | $175,000 | – | 156,195 | – | 0.05% | – |
| EVGN | New | EVOGENE LTD | $156,000 | – | 202,322 | – | 0.05% | – |
| ALGS | New | ALIGOS THERAPEUTICS INC | $71,000 | – | 58,392 | – | 0.02% | – |
| MSACW | New | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $9,000 | – | 49,990 | – | 0.00% | – |
| New | RENOVACOR INC*w exp 99/99/999 | $6,000 | – | 104,828 | – | 0.00% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MSACW | Exit | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $0 | – | -49,990 | – | -0.02% | – |
| CBIO | Exit | CATALYST BIOSCIENCES INC | $0 | – | -10,000 | – | -0.02% | – |
| Exit | RENOVACOR INC*w exp 99/99/999 | $0 | – | -104,828 | – | -0.02% | – | |
| Exit | ADAGIO THERAPEUTICS INC | $0 | – | -5,000 | – | -0.12% | – | |
| AFMD | Exit | AFFIMED N V | $0 | – | -47,182 | – | -0.16% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -19,432 | – | -0.17% | – |
| ARCT | Exit | ARCTURUS THERAPEUTICS HLDGS | $0 | – | -6,208 | – | -0.17% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -11,796 | – | -0.21% | – |
| SURF | Exit | SURFACE ONCOLOGY INC | $0 | – | -50,000 | – | -0.21% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -10,000 | – | -0.22% | – |
| CALA | Exit | CALITHERA BIOSCIENCES INC | $0 | – | -186,245 | – | -0.23% | – |
| EVLO | Exit | EVELO BIOSCIENCES INCput | $0 | – | -61,700 | – | -0.24% | – |
| AYLA | Exit | AYALA PHARMACEUTICALS INC | $0 | – | -40,956 | – | -0.26% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -30,000 | – | -0.28% | – |
| CRIS | Exit | CURIS INC | $0 | – | -62,070 | – | -0.28% | – |
| CABA | Exit | CABALETTA BIO INC | $0 | – | -42,022 | – | -0.29% | – |
| GH | Exit | GUARDANT HEALTH INC | $0 | – | -4,218 | – | -0.30% | – |
| CLXPF | Exit | CYBIN INC | $0 | – | -250,000 | – | -0.31% | – |
| PNT | Exit | POINT BIOPHARMA GLOBAL INC | $0 | – | -71,729 | – | -0.31% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -31,040 | – | -0.35% | – |
| EVGN | Exit | EVOGENE LTD | $0 | – | -248,327 | – | -0.37% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -4,950 | – | -0.38% | – |
| RNLX | Exit | RENALYTIX PLCads | $0 | – | -37,000 | – | -0.42% | – |
| MREO | Exit | MEREO BIOPHARMA GROUP PLCads | $0 | – | -365,661 | – | -0.50% | – |
| ATHA | Exit | ATHIRA PHARMA INC | $0 | – | -106,388 | – | -0.56% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -49,382 | – | -0.59% | – |
| DNAC | Exit | SOCIAL CAP SUVRETTA HLD CRPI | $0 | – | -106,000 | – | -0.59% | – |
| DNAD | Exit | SOCIAL CAP SUVRETTA HLDS CP | $0 | – | -106,000 | – | -0.59% | – |
| DNAB | Exit | SOCIAL CAP SUVRETTA HLDS CRP | $0 | – | -106,000 | – | -0.59% | – |
| DNAA | Exit | SOCIAL CAP SUVRETTA HLDS CRP | $0 | – | -106,000 | – | -0.60% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -56,614 | – | -0.60% | – |
| MSAC | Exit | MEDICUS SCIENCES ACQUISITION | $0 | – | -110,040 | – | -0.61% | – |
| ARNA | Exit | ARENA PHARMACEUTICALS INC | $0 | – | -18,581 | – | -0.62% | – |
| CGEN | Exit | COMPUGEN LTDord | $0 | – | -203,532 | – | -0.69% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -4,389 | – | -0.70% | – |
| DCPH | Exit | DECIPHERA PHARMACEUTICALS IN | $0 | – | -37,249 | – | -0.72% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -185,035 | – | -0.75% | – |
| EYPT | Exit | EYEPOINT PHARMACEUTICALS INC | $0 | – | -129,290 | – | -0.76% | – |
| ADMS | Exit | ADAMAS PHARMACEUTICALS INC | $0 | – | -288,042 | – | -0.80% | – |
| PYPD | Exit | POLYPID LTD | $0 | – | -183,230 | – | -0.81% | – |
| CGEN | Exit | COMPUGEN LTDcall | $0 | – | -248,000 | – | -0.84% | – |
| JNCE | Exit | JOUNCE THERAPEUTICS INC | $0 | – | -208,559 | – | -0.88% | – |
| STXS | Exit | STEREOTAXIS INC | $0 | – | -291,696 | – | -0.89% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -23,855 | – | -0.90% | – |
| LHDX | Exit | LUCIRA HEALTH INC | $0 | – | -220,758 | – | -0.95% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -106,078 | – | -0.99% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -49,309 | – | -1.00% | – |
| BNTC | Exit | BENITEC BIOPHARMA INC | $0 | – | -498,009 | – | -1.00% | – |
| MCRB | Exit | SERES THERAPEUTICS INC | $0 | – | -274,833 | – | -1.08% | – |
| VTGN | Exit | VISTAGEN THERAPEUTICS INC | $0 | – | -707,733 | – | -1.10% | – |
| OTIC | Exit | OTONOMY INC | $0 | – | -1,017,048 | – | -1.10% | – |
| Exit | ERASCA INC | $0 | – | -93,122 | – | -1.12% | – | |
| SGEN | Exit | SEAGEN INC | $0 | – | -11,749 | – | -1.13% | – |
| CYCC | Exit | CYCLACEL PHARMACEUTICALS INC | $0 | – | -388,632 | – | -1.16% | – |
| ELOX | Exit | ELOXX PHARMACEUTICALS INC | $0 | – | -1,259,840 | – | -1.16% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -38,243 | – | -1.17% | – |
| HLXA | Exit | HELIX ACQUISITION CORP | $0 | – | -223,906 | – | -1.26% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -365,000 | – | -1.27% | – |
| CCXI | Exit | CHEMOCENTRYX INCput | $0 | – | -139,200 | – | -1.35% | – |
| HALO | Exit | HALOZYME THERAPEUTICS INC | $0 | – | -60,170 | – | -1.38% | – |
| LPTX | Exit | LEAP THERAPEUTICS INC | $0 | – | -620,000 | – | -1.40% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -37,249 | – | -1.73% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -173,327 | – | -1.76% | – |
| ITOS | Exit | ITEOS THERAPEUTICS INC | $0 | – | -116,931 | – | -1.78% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -57,704 | – | -1.85% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -163,486 | – | -2.03% | – |
| IMGN | Exit | IMMUNOGEN INC | $0 | – | -649,919 | – | -2.08% | – |
| CERS | Exit | CERUS CORP | $0 | – | -619,369 | – | -2.13% | – |
| ITCI | Exit | INTRA-CELLULAR THERAPIES INC | $0 | – | -101,890 | – | -2.15% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -21,189 | – | -2.21% | – |
| RACB | Exit | RESEARCH ALLIANCE CORP II | $0 | – | -473,396 | – | -2.64% | – |
| INSM | Exit | INSMED INC | $0 | – | -174,588 | – | -2.72% | – |
| NXTC | Exit | NEXTCURE INC | $0 | – | -721,302 | – | -2.75% | – |
| FULC | Exit | FULCRUM THERAPEUTICS INC | $0 | – | -185,691 | – | -2.96% | – |
| IMTX | Exit | IMMATICS N.V | $0 | – | -437,866 | – | -3.22% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -677,900 | – | -3.22% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -52,469 | – | -3.25% | – |
| AMYT | Exit | AMRYT PHARMA PLCsponsored ads | $0 | – | -516,221 | – | -3.52% | – |
| MRUS | Exit | MERUS N V | $0 | – | -345,964 | – | -4.30% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -45,941 | – | -4.60% | – |
| VCYT | Exit | VERACYTE INC | $0 | – | -179,548 | – | -4.72% | – |
| BHVN | Exit | BIOHAVEN PHARMACTL HLDG CO L | $0 | – | -61,897 | – | -4.86% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO L | $8,598,000 | +56.4% | 61,897 | +9.3% | 4.86% | +98.2% |
| VCYT | Buy | VERACYTE INC | $8,340,000 | +38.3% | 179,548 | +19.0% | 4.72% | +75.3% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $8,127,000 | +33.3% | 45,941 | +21.7% | 4.60% | +68.9% |
| MRUS | Buy | MERUS N V | $7,611,000 | +12.6% | 345,964 | +7.8% | 4.30% | +42.7% |
| AMYT | Buy | AMRYT PHARMA PLCsponsored ads | $6,218,000 | +12.3% | 516,221 | +13.1% | 3.52% | +42.3% |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $5,747,000 | +22.7% | 52,469 | +4.9% | 3.25% | +55.5% |
| COGT | Buy | COGENT BIOSCIENCES INC | $5,701,000 | +254.5% | 677,900 | +242.0% | 3.22% | +349.5% |
| IMTX | Buy | IMMATICS N.V | $5,692,000 | +69.4% | 437,866 | +51.3% | 3.22% | +114.7% |
| FULC | New | FULCRUM THERAPEUTICS INC | $5,238,000 | – | 185,691 | – | 2.96% | – |
| NXTC | Buy | NEXTCURE INC | $4,862,000 | +112.0% | 721,302 | +152.6% | 2.75% | +168.7% |
| INSM | Sell | INSMED INC | $4,808,000 | -4.8% | 174,588 | -1.6% | 2.72% | +20.7% |
| RACB | Sell | RESEARCH ALLIANCE CORP II | $4,663,000 | -7.3% | 473,396 | -4.5% | 2.64% | +17.6% |
| UTHR | Buy | UNITED THERAPEUTICS CORP DEL | $3,911,000 | +42.6% | 21,189 | +38.6% | 2.21% | +80.8% |
| ITCI | Sell | INTRA-CELLULAR THERAPIES INC | $3,798,000 | -17.8% | 101,890 | -10.0% | 2.15% | +4.1% |
| CERS | Buy | CERUS CORP | $3,772,000 | +614.4% | 619,369 | +3213.7% | 2.13% | +807.2% |
| IMGN | Sell | IMMUNOGEN INC | $3,685,000 | -32.4% | 649,919 | -21.5% | 2.08% | -14.4% |
| SRRA | Buy | SIERRA ONCOLOGY INC | $3,584,000 | +32.2% | 163,486 | +17.4% | 2.03% | +67.4% |
| MORF | Sell | MORPHIC HLDG INC | $3,268,000 | -45.2% | 57,704 | -44.4% | 1.85% | -30.5% |
| ITOS | Buy | ITEOS THERAPEUTICS INC | $3,157,000 | +63.0% | 116,931 | +54.9% | 1.78% | +106.6% |
| ACRS | Sell | ACLARIS THERAPEUTICS INC | $3,120,000 | -5.9% | 173,327 | -8.2% | 1.76% | +19.4% |
| ARVN | New | ARVINAS INC | $3,061,000 | – | 37,249 | – | 1.73% | – |
| LPTX | New | LEAP THERAPEUTICS INC | $2,486,000 | – | 620,000 | – | 1.40% | – |
| HALO | Sell | HALOZYME THERAPEUTICS INC | $2,448,000 | -19.2% | 60,170 | -9.8% | 1.38% | +2.5% |
| CCXI | Buy | CHEMOCENTRYX INCput | $2,380,000 | +77.7% | 139,200 | +39.2% | 1.35% | +125.5% |
| BLU | Buy | BELLUS HEALTH INC NEW | $2,241,000 | +243.2% | 365,000 | +73.9% | 1.27% | +335.4% |
| HLXA | Sell | HELIX ACQUISITION CORP | $2,224,000 | -8.2% | 223,906 | -4.3% | 1.26% | +16.4% |
| CLDX | Buy | CELLDEX THERAPEUTICS INC NEW | $2,065,000 | -29.4% | 38,243 | +285.5% | 1.17% | -10.6% |
| ELOX | Sell | ELOXX PHARMACEUTICALS INC | $2,054,000 | -45.3% | 1,259,840 | -33.3% | 1.16% | -30.7% |
| CYCC | Buy | CYCLACEL PHARMACEUTICALS INC | $2,048,000 | +34.1% | 388,632 | +50.7% | 1.16% | +70.0% |
| SGEN | Buy | SEAGEN INC | $1,995,000 | +120.4% | 11,749 | +105.0% | 1.13% | +179.2% |
| New | ERASCA INC | $1,976,000 | – | 93,122 | – | 1.12% | – | |
| OTIC | Buy | OTONOMY INC | $1,953,000 | -8.1% | 1,017,048 | +6.7% | 1.10% | +16.5% |
| VTGN | Buy | VISTAGEN THERAPEUTICS INC | $1,939,000 | 0.0% | 707,733 | +15.0% | 1.10% | +26.7% |
| MCRB | Buy | SERES THERAPEUTICS INC | $1,913,000 | +25.5% | 274,833 | +330.0% | 1.08% | +59.1% |
| BNTC | Buy | BENITEC BIOPHARMA INC | $1,778,000 | -10.5% | 498,009 | +6.6% | 1.00% | +13.4% |
| CYTK | New | CYTOKINETICS INC | $1,762,000 | – | 49,309 | – | 1.00% | – |
| VRDN | Buy | VIRIDIAN THERAPEUTICS INC | $1,745,000 | +236.2% | 106,078 | +273.5% | 0.99% | +327.3% |
| LHDX | New | LUCIRA HEALTH INC | $1,678,000 | – | 220,758 | – | 0.95% | – |
| ZNTL | Sell | ZENTALIS PHARMACEUTICALS INC | $1,590,000 | -13.9% | 23,855 | -31.3% | 0.90% | +9.1% |
| STXS | Sell | STEREOTAXIS INC | $1,569,000 | -46.9% | 291,696 | -4.8% | 0.89% | -32.6% |
| JNCE | Sell | JOUNCE THERAPEUTICS INC | $1,550,000 | -9.0% | 208,559 | -16.8% | 0.88% | +15.3% |
| CGEN | New | COMPUGEN LTDcall | $1,481,000 | – | 248,000 | – | 0.84% | – |
| PYPD | Buy | POLYPID LTD | $1,426,000 | +1.9% | 183,230 | +18.5% | 0.81% | +29.2% |
| ADMS | Sell | ADAMAS PHARMACEUTICALS INC | $1,414,000 | -50.3% | 288,042 | -46.5% | 0.80% | -37.0% |
| EYPT | Sell | EYEPOINT PHARMACEUTICALS INC | $1,347,000 | -38.2% | 129,290 | -46.6% | 0.76% | -21.5% |
| VRAY | Buy | VIEWRAY INC | $1,334,000 | +114.1% | 185,035 | +96.0% | 0.75% | +171.2% |
| DCPH | Sell | DECIPHERA PHARMACEUTICALS IN | $1,266,000 | -7.2% | 37,249 | -0.0% | 0.72% | +17.8% |
| BIIB | New | BIOGEN INC | $1,242,000 | – | 4,389 | – | 0.70% | – |
| CGEN | Sell | COMPUGEN LTDord | $1,215,000 | -29.8% | 203,532 | -2.7% | 0.69% | -11.0% |
| ARNA | Sell | ARENA PHARMACEUTICALS INC | $1,106,000 | -21.2% | 18,581 | -9.7% | 0.62% | -0.2% |
| MSAC | Sell | MEDICUS SCIENCES ACQUISITION | $1,073,000 | -70.2% | 110,040 | -70.5% | 0.61% | -62.2% |
| KURA | Sell | KURA ONCOLOGY INC | $1,060,000 | -38.4% | 56,614 | -31.4% | 0.60% | -22.0% |
| DNAA | Sell | SOCIAL CAP SUVRETTA HLDS CRP | $1,055,000 | -58.3% | 106,000 | -57.6% | 0.60% | -47.1% |
| DNAB | Sell | SOCIAL CAP SUVRETTA HLDS CRP | $1,047,000 | -58.6% | 106,000 | -57.6% | 0.59% | -47.5% |
| DNAD | Sell | SOCIAL CAP SUVRETTA HLDS CP | $1,040,000 | -58.8% | 106,000 | -57.6% | 0.59% | -47.8% |
| DNAC | Sell | SOCIAL CAP SUVRETTA HLD CRPI | $1,039,000 | -58.9% | 106,000 | -57.6% | 0.59% | -47.9% |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $1,039,000 | – | 49,382 | – | 0.59% | – |
| ATHA | Sell | ATHIRA PHARMA INC | $998,000 | -17.4% | 106,388 | -9.8% | 0.56% | +4.6% |
| MREO | Sell | MEREO BIOPHARMA GROUP PLCads | $885,000 | -31.2% | 365,661 | -9.9% | 0.50% | -12.9% |
| RNLX | Sell | RENALYTIX PLCads | $742,000 | -80.9% | 37,000 | -70.7% | 0.42% | -75.9% |
| NTLA | New | INTELLIA THERAPEUTICS INC | $664,000 | – | 4,950 | – | 0.38% | – |
| EVGN | Sell | EVOGENE LTD | $656,000 | -46.9% | 248,327 | -31.3% | 0.37% | -32.7% |
| DRNA | Sell | DICERNA PHARMACEUTICALS INC | $626,000 | -92.7% | 31,040 | -86.5% | 0.35% | -90.7% |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $552,000 | – | 71,729 | – | 0.31% | – |
| CLXPF | New | CYBIN INC | $549,000 | – | 250,000 | – | 0.31% | – |
| GH | Sell | GUARDANT HEALTH INC | $527,000 | -9.1% | 4,218 | -9.7% | 0.30% | +15.1% |
| CABA | New | CABALETTA BIO INC | $511,000 | – | 42,022 | – | 0.29% | – |
| ISEE | New | IVERIC BIO INC | $487,000 | – | 30,000 | – | 0.28% | – |
| CRIS | Sell | CURIS INC | $486,000 | -76.8% | 62,070 | -76.1% | 0.28% | -70.6% |
| AYLA | Buy | AYALA PHARMACEUTICALS INC | $464,000 | +95.0% | 40,956 | +75.3% | 0.26% | +147.2% |
| EVLO | New | EVELO BIOSCIENCES INCput | $434,000 | – | 61,700 | – | 0.24% | – |
| CALA | Buy | CALITHERA BIOSCIENCES INC | $406,000 | +515.2% | 186,245 | +493.5% | 0.23% | +693.1% |
| KROS | New | KEROS THERAPEUTICS INC | $396,000 | – | 10,000 | – | 0.22% | – |
| SURF | Sell | SURFACE ONCOLOGY INC | $379,000 | -46.2% | 50,000 | -47.1% | 0.21% | -31.8% |
| RAPT | Sell | RAPT THERAPEUTICS INC | $366,000 | -75.6% | 11,796 | -75.0% | 0.21% | -69.1% |
| XENE | New | XENON PHARMACEUTICALS INC | $297,000 | – | 19,432 | – | 0.17% | – |
| ARCT | New | ARCTURUS THERAPEUTICS HLDGS | $297,000 | – | 6,208 | – | 0.17% | – |
| AFMD | Sell | AFFIMED N V | $292,000 | -83.0% | 47,182 | -76.7% | 0.16% | -78.5% |
| New | ADAGIO THERAPEUTICS INC | $211,000 | – | 5,000 | – | 0.12% | – | |
| New | RENOVACOR INC*w exp 99/99/999 | $42,000 | – | 104,828 | – | 0.02% | – | |
| CBIO | New | CATALYST BIOSCIENCES INC | $41,000 | – | 10,000 | – | 0.02% | – |
| PHGE | Exit | BIOMX INC | $0 | – | -14,207 | – | -0.04% | – |
| CHAQWS | Exit | CHARDAN HEALTHCR ACQSTN 2 CO*w exp 03/05/202 | $0 | – | -104,828 | – | -0.04% | – |
| ETON | Exit | ETON PHARMACEUTICALS INC | $0 | – | -18,691 | – | -0.05% | – |
| FMTX | Exit | FORMA THERAPEUTICS HLDGS INC | $0 | – | -9,679 | – | -0.11% | – |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -2,480 | – | -0.11% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -9,346 | – | -0.13% | – |
| MDNA | Exit | MEDICENNA THERAPEUTICS CORP | $0 | – | -110,515 | – | -0.15% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -14,882 | – | -0.16% | – |
| Exit | CATABASIS PHARMACEUTICALS IN | $0 | – | -188,777 | – | -0.18% | – | |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -7,009 | – | -0.20% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -10,293 | – | -0.20% | – |
| SLRX | Exit | SALARIUS PHARMACEUTICALS INC | $0 | – | -471,885 | – | -0.22% | – |
| ETNB | Exit | 89BIO INC | $0 | – | -28,032 | – | -0.23% | – |
| SAGE | Exit | SAGE THERAPEUTICS INCcall | $0 | – | -9,300 | – | -0.24% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -34,727 | – | -0.27% | – |
| ODT | Exit | ODONATE THERAPEUTICS INC | $0 | – | -186,680 | – | -0.29% | – |
| ASND | Exit | ASCENDIS PHARMA A/Ssponsored adr | $0 | – | -5,599 | – | -0.33% | – |
| ARDX | Exit | ARDELYX INC | $0 | – | -99,237 | – | -0.34% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -33,028 | – | -0.36% | – |
| WVE | Exit | WAVE LIFE SCIENCES LTD | $0 | – | -123,972 | – | -0.37% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -95,190 | – | -0.41% | – | |
| DCTH | Exit | DELCATH SYS INC | $0 | – | -99,189 | – | -0.56% | – |
| RETA | Exit | REATA PHARMACEUTICALS INCcl a | $0 | – | -9,346 | – | -0.59% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -46,729 | – | -0.67% | – |
| CERE | Exit | CEREVEL THERAPEUTICS HLDNG I | $0 | – | -15,000 | – | -0.74% | – |
| RCUS | Exit | ARCUS BIOSCIENCES INCput | $0 | – | -60,400 | – | -0.74% | – |
| MRSN | Exit | MERSANA THERAPEUTICS INC | $0 | – | -125,123 | – | -0.76% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -75,732 | – | -0.87% | – |
| ALDX | Exit | ALDEYRA THERAPEUTICS INC | $0 | – | -192,345 | – | -0.97% | – |
| MCRB | Exit | SERES THERAPEUTICS INCcall | $0 | – | -122,700 | – | -1.30% | – |
| TCRR | Exit | TCR2 THERAPEUTICS INC | $0 | – | -188,142 | – | -1.38% | – |
| VSTM | Exit | VERASTEM INC | $0 | – | -1,049,357 | – | -1.90% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -176,915 | – | -2.12% | – |
| XBI | Exit | SPDR SER TRcall | $0 | – | -94,400 | – | -5.70% | – |
| KDNY | Exit | CHINOOK THERAPEUTICS INC | $0 | – | -14,158 | – | -5.70% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KDNY | New | CHINOOK THERAPEUTICS INC | $12,782,000 | – | 14,158 | – | 5.70% | – |
| XBI | New | SPDR SER TRcall | $12,782,000 | – | 94,400 | – | 5.70% | – |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $8,580,000 | – | 229,892 | – | 3.83% | – |
| MRUS | New | MERUS N V | $6,760,000 | – | 320,815 | – | 3.02% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $6,098,000 | – | 37,753 | – | 2.72% | – |
| VCYT | New | VERACYTE INC | $6,031,000 | – | 150,861 | – | 2.69% | – |
| MORF | New | MORPHIC HLDG INC | $5,960,000 | – | 103,858 | – | 2.66% | – |
| AMYT | New | AMRYT PHARMA PLCsponsored ads | $5,538,000 | – | 456,537 | – | 2.47% | – |
| BHVN | New | BIOHAVEN PHARMACTL HLDG CO L | $5,497,000 | – | 56,626 | – | 2.45% | – |
| IMGN | New | IMMUNOGEN INC | $5,454,000 | – | 827,587 | – | 2.43% | – |
| INSM | New | INSMED INC | $5,050,000 | – | 177,433 | – | 2.25% | – |
| RACB | New | RESEARCH ALLIANCE CORP II | $5,028,000 | – | 495,855 | – | 2.24% | – |
| MGNX | New | MACROGENICS INC | $4,752,000 | – | 176,915 | – | 2.12% | – |
| HZNP | New | HORIZON THERAPEUTICS PUB L | $4,685,000 | – | 50,035 | – | 2.09% | – |
| ITCI | New | INTRA-CELLULAR THERAPIES INC | $4,623,000 | – | 113,258 | – | 2.06% | – |
| VSTM | New | VERASTEM INC | $4,271,000 | – | 1,049,357 | – | 1.90% | – |
| RNLX | New | RENALYTIX PLCads | $3,893,000 | – | 126,145 | – | 1.74% | – |
| ELOX | New | ELOXX PHARMACEUTICALS INC | $3,756,000 | – | 1,887,539 | – | 1.68% | – |
| MSAC | New | MEDICUS SCIENCES ACQUISITION | $3,602,000 | – | 373,275 | – | 1.61% | – |
| IMTX | New | IMMATICS N.V | $3,360,000 | – | 289,408 | – | 1.50% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $3,314,000 | – | 188,719 | – | 1.48% | – |
| TCRR | New | TCR2 THERAPEUTICS INC | $3,087,000 | – | 188,142 | – | 1.38% | – |
| HALO | New | HALOZYME THERAPEUTICS INC | $3,028,000 | – | 66,673 | – | 1.35% | – |
| STXS | New | STEREOTAXIS INC | $2,954,000 | – | 306,404 | – | 1.32% | – |
| MCRB | New | SERES THERAPEUTICS INCcall | $2,926,000 | – | 122,700 | – | 1.30% | – |
| CLDX | New | CELLDEX THERAPEUTICS INC NEW | $2,926,000 | – | 9,921 | – | 1.30% | – |
| ADMS | New | ADAMAS PHARMACEUTICALS INC | $2,845,000 | – | 538,744 | – | 1.27% | – |
| UTHR | New | UNITED THERAPEUTICS CORP DEL | $2,743,000 | – | 15,289 | – | 1.22% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $2,712,000 | – | 139,305 | – | 1.21% | – |
| DNAB | New | SOCIAL CAP SUVRETTA HLDS CRP | $2,530,000 | – | 250,000 | – | 1.13% | – |
| DNAA | New | SOCIAL CAP SUVRETTA HLDS CRP | $2,528,000 | – | 250,000 | – | 1.13% | – |
| DNAC | New | SOCIAL CAP SUVRETTA HLD CRPI | $2,528,000 | – | 250,000 | – | 1.13% | – |
| DNAD | New | SOCIAL CAP SUVRETTA HLDS CP | $2,525,000 | – | 250,000 | – | 1.13% | – |
| HLXA | New | HELIX ACQUISITION CORP | $2,422,000 | – | 234,020 | – | 1.08% | – |
| NXTC | New | NEXTCURE INC | $2,293,000 | – | 285,498 | – | 1.02% | – |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $2,179,000 | – | 192,345 | – | 0.97% | – |
| EYPT | New | EYEPOINT PHARMACEUTICALS INC | $2,178,000 | – | 242,309 | – | 0.97% | – |
| OTIC | New | OTONOMY INC | $2,126,000 | – | 953,434 | – | 0.95% | – |
| CRIS | New | CURIS INC | $2,094,000 | – | 259,539 | – | 0.93% | – |
| BNTC | New | BENITEC BIOPHARMA INC | $1,986,000 | – | 467,256 | – | 0.89% | – |
| CGEM | New | CULLINAN ONCOLOGY INC | $1,950,000 | – | 75,732 | – | 0.87% | – |
| VTGN | New | VISTAGEN THERAPEUTICS INC | $1,939,000 | – | 615,547 | – | 0.86% | – |
| ITOS | New | ITEOS THERAPEUTICS INC | $1,937,000 | – | 75,511 | – | 0.86% | – |
| ZNTL | New | ZENTALIS PHARMACEUTICALS INC | $1,847,000 | – | 34,725 | – | 0.82% | – |
| CGEN | New | COMPUGEN LTDord | $1,731,000 | – | 209,113 | – | 0.77% | – |
| KURA | New | KURA ONCOLOGY INC | $1,722,000 | – | 82,573 | – | 0.77% | – |
| AFMD | New | AFFIMED N V | $1,719,000 | – | 202,190 | – | 0.77% | – |
| JNCE | New | JOUNCE THERAPEUTICS INC | $1,704,000 | – | 250,644 | – | 0.76% | – |
| MRSN | New | MERSANA THERAPEUTICS INC | $1,699,000 | – | 125,123 | – | 0.76% | – |
| CERE | New | CEREVEL THERAPEUTICS HLDNG I | $1,659,000 | – | 15,000 | – | 0.74% | – |
| RCUS | New | ARCUS BIOSCIENCES INCput | $1,659,000 | – | 60,400 | – | 0.74% | – |
| COGT | New | COGENT BIOSCIENCES INC | $1,608,000 | – | 198,245 | – | 0.72% | – |
| CYCC | New | CYCLACEL PHARMACEUTICALS INC | $1,527,000 | – | 257,958 | – | 0.68% | – |
| MCRB | New | SERES THERAPEUTICS INC | $1,524,000 | – | 63,915 | – | 0.68% | – |
| RAPT | New | RAPT THERAPEUTICS INC | $1,500,000 | – | 47,194 | – | 0.67% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $1,496,000 | – | 46,729 | – | 0.67% | – |
| ARNA | New | ARENA PHARMACEUTICALS INC | $1,403,000 | – | 20,577 | – | 0.63% | – |
| PYPD | New | POLYPID LTD | $1,400,000 | – | 154,566 | – | 0.62% | – |
| DCPH | New | DECIPHERA PHARMACEUTICALS IN | $1,364,000 | – | 37,257 | – | 0.61% | – |
| CCXI | New | CHEMOCENTRYX INCput | $1,339,000 | – | 100,000 | – | 0.60% | – |
| RETA | New | REATA PHARMACEUTICALS INCcl a | $1,323,000 | – | 9,346 | – | 0.59% | – |
| MREO | New | MEREO BIOPHARMA GROUP PLCads | $1,287,000 | – | 405,871 | – | 0.57% | – |
| DCTH | New | DELCATH SYS INC | $1,251,000 | – | 99,189 | – | 0.56% | – |
| EVGN | New | EVOGENE LTD | $1,235,000 | – | 361,254 | – | 0.55% | – |
| ATHA | New | ATHIRA PHARMA INC | $1,208,000 | – | 117,980 | – | 0.54% | – |
| New | TRILLIUM THERAPEUTICS INC | $923,000 | – | 95,190 | – | 0.41% | – | |
| SGEN | New | SEAGEN INC | $905,000 | – | 5,732 | – | 0.40% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $826,000 | – | 123,972 | – | 0.37% | – |
| AKRO | New | AKERO THERAPEUTICS INC | $819,000 | – | 33,028 | – | 0.36% | – |
| ARDX | New | ARDELYX INC | $752,000 | – | 99,237 | – | 0.34% | – |
| ASND | New | ASCENDIS PHARMA A/Ssponsored adr | $737,000 | – | 5,599 | – | 0.33% | – |
| SURF | New | SURFACE ONCOLOGY INC | $705,000 | – | 94,539 | – | 0.31% | – |
| ODT | New | ODONATE THERAPEUTICS INC | $652,000 | – | 186,680 | – | 0.29% | – |
| BLU | New | BELLUS HEALTH INC NEW | $653,000 | – | 209,933 | – | 0.29% | – |
| VRAY | New | VIEWRAY INC | $623,000 | – | 94,388 | – | 0.28% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $596,000 | – | 34,727 | – | 0.27% | – |
| GH | New | GUARDANT HEALTH INC | $580,000 | – | 4,673 | – | 0.26% | – |
| SAGE | New | SAGE THERAPEUTICS INCcall | $528,000 | – | 9,300 | – | 0.24% | – |
| CERS | New | CERUS CORP | $528,000 | – | 18,691 | – | 0.24% | – |
| ETNB | New | 89BIO INC | $524,000 | – | 28,032 | – | 0.23% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $519,000 | – | 28,399 | – | 0.23% | – |
| SLRX | New | SALARIUS PHARMACEUTICALS INC | $500,000 | – | 471,885 | – | 0.22% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $456,000 | – | 10,293 | – | 0.20% | – |
| APLS | New | APELLIS PHARMACEUTICALS INC | $443,000 | – | 7,009 | – | 0.20% | – |
| New | CATABASIS PHARMACEUTICALS IN | $398,000 | – | 188,777 | – | 0.18% | – | |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $357,000 | – | 14,882 | – | 0.16% | – |
| MDNA | New | MEDICENNA THERAPEUTICS CORP | $333,000 | – | 110,515 | – | 0.15% | – |
| QURE | New | UNIQURE NV | $288,000 | – | 9,346 | – | 0.13% | – |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $242,000 | – | 2,480 | – | 0.11% | – |
| FMTX | New | FORMA THERAPEUTICS HLDGS INC | $241,000 | – | 9,679 | – | 0.11% | – |
| AYLA | New | AYALA PHARMACEUTICALS INC | $238,000 | – | 23,364 | – | 0.11% | – |
| ETON | New | ETON PHARMACEUTICALS INC | $115,000 | – | 18,691 | – | 0.05% | – |
| CHAQWS | New | CHARDAN HEALTHCR ACQSTN 2 CO*w exp 03/05/202 | $85,000 | – | 104,828 | – | 0.04% | – |
| PHGE | New | BIOMX INC | $78,000 | – | 14,207 | – | 0.04% | – |
| CALA | New | CALITHERA BIOSCIENCES INC | $66,000 | – | 31,382 | – | 0.03% | – |
| MSACW | New | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $50,000 | – | 49,990 | – | 0.02% | – |