$183 Million is the total value of SILVERARC CAPITAL MANAGEMENT, LLC's 91 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 56.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ACRS | New | ACLARIS THERAPEUTICS INC | $8,486,000 | – | 336,737 | +100.0% | 4.63% | – |
| CRIS | Buy | CURIS INC | $7,118,000 | +64.0% | 628,793 | +18.6% | 3.88% | +54.0% |
| VCEL | Sell | VERICEL CORP | $6,784,000 | -21.9% | 122,125 | -56.6% | 3.70% | -26.7% |
| INSM | Buy | INSMED INC | $6,499,000 | +11.6% | 190,810 | +9.0% | 3.54% | +4.7% |
| AMYT | Buy | AMRYT PHARMA PLCsponsored ads | $5,988,000 | +5.1% | 429,863 | +6.8% | 3.27% | -1.4% |
| IMGN | Buy | IMMUNOGEN INC | $5,908,000 | +52.7% | 729,364 | +21.6% | 3.22% | +43.4% |
| RACB | New | RESEARCH ALLIANCE CORP II | $5,125,000 | – | 500,000 | +100.0% | 2.80% | – |
| DRNA | Sell | DICERNA PHARMACEUTICALS INC | $5,114,000 | +2.1% | 200,000 | -12.0% | 2.79% | -4.2% |
| MRUS | New | MERUS N V | $5,112,000 | – | 244,713 | +100.0% | 2.79% | – |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $4,462,000 | +103.3% | 48,476 | +61.6% | 2.43% | +90.9% |
| ITCI | Sell | INTRA CELLULAR THERAPIES INC | $4,415,000 | -30.6% | 130,117 | -34.9% | 2.41% | -34.8% |
| HALO | Buy | HALOZYME THERAPEUTICS INC | $4,375,000 | +2.4% | 104,945 | +4.9% | 2.39% | -3.8% |
| MSACU | New | MEDICUS SCIENCES ACQUISITIONunit 99/99/9999 | $4,007,000 | – | 406,791 | +100.0% | 2.19% | – |
| AFMD | Buy | AFFIMED N V | $3,973,000 | +70.7% | 502,330 | +25.6% | 2.17% | +60.2% |
| ALDX | New | ALDEYRA THERAPEUTICS INC | $3,824,000 | – | 321,879 | +100.0% | 2.09% | – |
| MORF | Buy | MORPHIC HLDG INC | $3,797,000 | +120.0% | 60,000 | +16.7% | 2.07% | +106.5% |
| JNCE | Sell | JOUNCE THERAPEUTICS INC | $3,595,000 | +26.3% | 350,000 | -13.9% | 1.96% | +18.6% |
| RNLX | Sell | RENALYTIX AI PLCads | $3,453,000 | +52.8% | 134,555 | -4.7% | 1.88% | +43.4% |
| TCRR | Buy | TCR2 THERAPEUTICS INC | $3,426,000 | -18.5% | 155,145 | +14.1% | 1.87% | -23.5% |
| BHVN | Buy | BIOHAVEN PHARMACTL HLDG CO L | $3,424,000 | +142.1% | 50,089 | +203.6% | 1.87% | +127.3% |
| VCYT | New | VERACYTE INC | $3,225,000 | – | 60,000 | +100.0% | 1.76% | – |
| EYPT | New | EYEPOINT PHARMACEUTICALS INC | $3,048,000 | – | 300,000 | +100.0% | 1.66% | – |
| VSTM | Buy | VERASTEM INC | $2,958,000 | +22.3% | 1,197,489 | +5.4% | 1.61% | +14.8% |
| SLRX | New | SALARIUS PHARMACEUTICALS INC | $2,948,000 | – | 1,992,181 | +100.0% | 1.61% | – |
| CCXI | Buy | CHEMOCENTRYX INC | $2,868,000 | -13.8% | 55,974 | +4.1% | 1.56% | -19.1% |
| LRMR | Sell | LARIMAR THERAPEUTICS INC | $2,804,000 | -39.7% | 191,945 | -11.6% | 1.53% | -43.4% |
| BIIB | New | BIOGEN INCcall | $2,798,000 | – | 10,000 | +100.0% | 1.53% | – |
| ADMS | Buy | ADAMAS PHARMACEUTICALS INC | $2,508,000 | +31.4% | 522,589 | +18.5% | 1.37% | +23.4% |
| ASND | Buy | ASCENDIS PHARMA A/Ssponsored adr | $2,409,000 | -17.7% | 18,694 | +6.5% | 1.31% | -22.8% |
| HLXA | Buy | HELIX ACQUISITION CORP | $2,333,000 | -4.6% | 228,485 | +6.2% | 1.27% | -10.4% |
| SRRA | Sell | SIERRA ONCOLOGY INC | $2,321,000 | +7.3% | 134,681 | -0.2% | 1.27% | +0.7% |
| KURA | Sell | KURA ONCOLOGY INC | $2,262,000 | -23.0% | 80,000 | -11.1% | 1.23% | -27.7% |
| EPIX | Sell | ESSA PHARMA INC | $2,134,000 | -44.6% | 73,451 | -77.3% | 1.16% | -48.0% |
| MCRB | Buy | SERES THERAPEUTICS INC | $2,059,000 | +235.9% | 100,000 | +300.0% | 1.12% | +215.4% |
| SRRK | Buy | SCHOLAR ROCK HLDG CORP | $1,835,000 | +51.3% | 36,221 | +44.9% | 1.00% | +42.0% |
| ONCR | New | ONCORUS INC | $1,810,000 | – | 130,000 | +100.0% | 0.99% | – |
| DCPH | Buy | DECIPHERA PHARMACEUTICALS IN | $1,783,000 | -19.1% | 39,765 | +3.0% | 0.97% | -24.0% |
| CYCC | New | CYCLACEL PHARMACEUTICALS INC | $1,778,000 | – | 250,000 | +100.0% | 0.97% | – |
| EVGN | Sell | EVOGENE LTD | $1,764,000 | -37.4% | 350,000 | -41.7% | 0.96% | -41.3% |
| ODT | New | ODONATE THERAPEUTICS INC | $1,710,000 | – | 500,000 | +100.0% | 0.93% | – |
| ARVN | Sell | ARVINAS INC | $1,657,000 | -64.5% | 25,071 | -54.4% | 0.90% | -66.7% |
| VRTX | Buy | VERTEX PHARMACEUTICALS INC | $1,612,000 | +36.4% | 7,500 | +50.0% | 0.88% | +27.9% |
| TPTX | Buy | TURNING POINT THERAPEUTICS I | $1,584,000 | -19.4% | 16,741 | +3.8% | 0.86% | -24.3% |
| GH | Sell | GUARDANT HEALTH INC | $1,556,000 | -35.9% | 10,192 | -45.9% | 0.85% | -39.7% |
| SAGE | New | SAGE THERAPEUTICS INCcall | $1,497,000 | – | 20,000 | +100.0% | 0.82% | – |
| CHRS | New | COHERUS BIOSCIENCES INC | $1,461,000 | – | 100,000 | +100.0% | 0.80% | – |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $1,429,000 | +652.1% | 121,302 | +648.4% | 0.78% | +608.2% |
| BIIB | Buy | BIOGEN INC | $1,399,000 | +90.3% | 5,000 | +66.7% | 0.76% | +78.7% |
| ARNA | ARENA PHARMACEUTICALS INC | $1,388,000 | -9.7% | 20,000 | 0.0% | 0.76% | -15.2% | |
| PYPD | New | POLYPID LTD | $1,372,000 | – | 149,826 | +100.0% | 0.75% | – |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $1,285,000 | – | 50,000 | +100.0% | 0.70% | – |
| ETNB | Buy | 89BIO INC | $1,184,000 | +10.4% | 50,007 | +13.6% | 0.65% | +3.7% |
| COGT | Sell | UNUM THERAPEUTICS INC | $1,054,000 | -60.1% | 120,000 | -49.0% | 0.58% | -62.5% |
| CLRB | Sell | CELLECTAR BIOSCIENCES INC | $976,000 | -73.5% | 606,358 | -65.8% | 0.53% | -75.2% |
| AKRO | Sell | AKERO THERAPEUTICS INC | $928,000 | +2.2% | 32,000 | -9.0% | 0.51% | -4.2% |
| UTHR | UNITED THERAPEUTICS CORP DEL | $897,000 | +10.2% | 5,364 | 0.0% | 0.49% | +3.4% | |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $857,000 | -80.5% | 5,000 | -75.0% | 0.47% | -81.7% |
| IMVT | Sell | IMMUNOVANT INC | $808,000 | -82.5% | 50,400 | -49.6% | 0.44% | -83.6% |
| ISEE | IVERIC BIO INC | $804,000 | -10.6% | 130,043 | 0.0% | 0.44% | -15.9% | |
| SURF | Sell | SURFACE ONCOLOGY INC | $780,000 | -35.1% | 100,000 | -23.1% | 0.42% | -39.1% |
| SGEN | Sell | SEAGEN INC | $694,000 | -47.2% | 5,000 | -33.4% | 0.38% | -50.4% |
| KALA | KALA PHARMACEUTICALS INC | $689,000 | -0.6% | 102,198 | 0.0% | 0.38% | -6.7% | |
| Sell | TRILLIUM THERAPEUTICS INC | $644,000 | -60.2% | 60,000 | -45.5% | 0.35% | -62.7% | |
| CGEN | Sell | COMPUGEN LTDord | $644,000 | -64.7% | 75,000 | -50.2% | 0.35% | -66.9% |
| OTIC | Sell | OTONOMY INC | $640,000 | -62.5% | 250,995 | -4.9% | 0.35% | -64.8% |
| New | APTOSE BIOSCIENCES INC | $598,000 | – | 100,000 | +100.0% | 0.33% | – | |
| MREO | Sell | MEREO BIOPHARMA GROUP PLCads | $590,000 | -41.1% | 175,000 | -37.5% | 0.32% | -44.7% |
| LPTX | Buy | LEAP THERAPEUTICS INC | $570,000 | -7.9% | 300,000 | +9.1% | 0.31% | -13.6% |
| WVE | New | WAVE LIFE SCIENCES LTDcall | $561,000 | – | 100,000 | +100.0% | 0.31% | – |
| BLRX | New | BIOLINERX LTDsponsored ads | $558,000 | – | 200,000 | +100.0% | 0.30% | – |
| TVTX | New | TRAVERE THERAPEUTICS INC | $499,000 | – | 20,000 | +100.0% | 0.27% | – |
| DCTH | Sell | DELCATH SYS INC | $497,000 | -92.1% | 40,000 | -88.6% | 0.27% | -92.6% |
| IMTX | New | IMMATICS N.V | $469,000 | – | 41,797 | +100.0% | 0.26% | – |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $461,000 | – | 27,586 | +100.0% | 0.25% | – |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $447,000 | -33.0% | 20,000 | -33.3% | 0.24% | -37.1% |
| RCKT | ROCKET PHARMACEUTICALS INC | $444,000 | -19.0% | 10,000 | 0.0% | 0.24% | -23.9% | |
| MDNA | MEDICENNA THERAPEUTICS CORP | $439,000 | -12.7% | 107,536 | 0.0% | 0.24% | -18.2% | |
| RACA | Buy | THERAPEUTICS ACQUISITION COR | $420,000 | -22.7% | 40,000 | +2.5% | 0.23% | -27.3% |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $405,000 | +41.6% | 25,000 | +132.3% | 0.22% | +33.1% |
| ATNM | Sell | ACTINIUM PHARMACEUTICALS INC | $350,000 | -50.1% | 45,910 | -49.0% | 0.19% | -53.2% |
| ARDX | Sell | ARDELYX INC | $298,000 | -61.6% | 45,000 | -62.5% | 0.16% | -63.9% |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $274,000 | – | 15,000 | +100.0% | 0.15% | – |
| VIRX | New | VIRACTA THERAPEUTICS INC | $264,000 | – | 28,570 | +100.0% | 0.14% | – |
| WVE | New | WAVE LIFE SCIENCES LTD | $224,000 | – | 40,000 | +100.0% | 0.12% | – |
| GMDA | Sell | GAMIDA CELL LTD | $189,000 | -68.2% | 23,393 | -67.0% | 0.10% | -70.1% |
| SLNO | Sell | SOLENO THERAPEUTICS INC | $158,000 | -74.6% | 125,000 | -61.3% | 0.09% | -76.2% |
| BDTX | New | BLACK DIAMOND THERAPEUTICS I | $146,000 | – | 6,000 | +100.0% | 0.08% | – |
| PIRS | New | PIERIS PHARMACEUTICALS INC | $129,000 | – | 50,000 | +100.0% | 0.07% | – |
| PHGE | BIOMX INC | $98,000 | +11.4% | 13,759 | 0.0% | 0.05% | +3.9% | |
| CHAQWS | CHARDAN HEALTHCR ACQSTN 2 CO*w exp 03/05/202 | $93,000 | +89.8% | 98,756 | 0.0% | 0.05% | +82.1% | |
| CALA | Buy | CALITHERA BIOSCIENCES INC | $73,000 | -1.4% | 30,000 | +100.0% | 0.04% | -7.0% |
| BNGOW | Exit | BIONANO GENOMICS INC*w exp 08/21/202 | $0 | – | -10,000 | -100.0% | -0.01% | – |
| ARQT | Exit | ARCUTIS BIOTHERAPEUTICS INC | $0 | – | -8,505 | -100.0% | -0.14% | – |
| Exit | COMPUGEN LTDcall | $0 | – | -20,000 | -100.0% | -0.14% | – | |
| APTX | Exit | APTINYX INC | $0 | – | -107,536 | -100.0% | -0.22% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -20,910 | -100.0% | -0.24% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -10,000 | -100.0% | -0.27% | – |
| ZNTL | Exit | ZENTALIS PHARMACEUTICALS INC | $0 | – | -10,000 | -100.0% | -0.30% | – |
| VYNE | Exit | VYNE THERAPEUTICS INC | $0 | – | -349,624 | -100.0% | -0.32% | – |
| EXAS | Exit | EXACT SCIENCES CORP | $0 | – | -5,000 | -100.0% | -0.38% | – |
| CNST | Exit | CONSTELLATION PHARMCETICLS I | $0 | – | -25,200 | -100.0% | -0.42% | – |
| Exit | CALITHERA BIOSCIENCES INCcall | $0 | – | -150,000 | -100.0% | -0.43% | – | |
| ALXN | Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -5,000 | -100.0% | -0.45% | – |
| BCRX | Exit | BIOCRYST PHARMACEUTICALS INC | $0 | – | -110,000 | -100.0% | -0.48% | – |
| NKTX | Exit | NKARTA INC | $0 | – | -15,000 | -100.0% | -0.54% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -241,756 | -100.0% | -0.58% | – |
| CLDX | Exit | CELLDEX THERAPEUTICS INC NEW | $0 | – | -80,282 | -100.0% | -0.82% | – |
| NXTC | Exit | NEXTCURE INC | $0 | – | -130,000 | -100.0% | -0.82% | – |
| ZYME | Exit | ZYMEWORKS INC | $0 | – | -30,834 | -100.0% | -0.85% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -185,000 | -100.0% | -2.33% | – |
| Exit | BIOGEN INCcall | $0 | – | -30,000 | -100.0% | -4.27% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-18
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| INTRA-CELLULAR THERAPIES INC | 12 | Q3 2023 | 7.8% |
| IMMUNOGEN INC | 12 | Q3 2023 | 8.3% |
| Morphic Holding Inc | 12 | Q3 2023 | 4.5% |
| UNUM THERAPEUTICS INC | 12 | Q3 2023 | 3.2% |
| INSMED INC | 12 | Q3 2023 | 3.5% |
| UNITED THERAPEUTICS CORP DEL | 12 | Q3 2023 | 2.2% |
| MERUS N V | 11 | Q3 2023 | 5.1% |
| VERACYTE INC | 11 | Q3 2023 | 4.9% |
| EVOGENE LTD | 11 | Q3 2023 | 1.6% |
| COMPUGEN LTD | 11 | Q3 2023 | 1.1% |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Benitec Biopharma Inc.Sold out | February 08, 2023 | 0 | 0.0% |
| DELCATH SYSTEMS, INC.Sold out | February 08, 2022 | 0 | 0.0% |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2023-11-13 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| 13F-HR | 2023-02-14 |
| SC 13G/A | 2023-02-08 |
| 13F-HR | 2022-10-28 |
View SILVERARC CAPITAL MANAGEMENT, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.