$372 Million is the total value of 5AM Venture Management, LLC's 21 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 28.6% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CINCOR PHARMA INC | $60,683,669 | -62.6% | 4,937,646 | 0.0% | 16.31% | -47.5% | ||
| ENTRADA THERAPEUTICS INC | $59,601,284 | -14.2% | 4,408,379 | 0.0% | 16.02% | +20.3% | ||
| VOR | VOR BIOPHARMA INC | $42,305,458 | +67.1% | 6,361,723 | 0.0% | 11.37% | +134.4% | |
| RALLYBIO CORP | $24,510,857 | -54.6% | 3,730,724 | 0.0% | 6.59% | -36.3% | ||
| IDYA | IDEAYA BIOSCIENCES INC | $21,736,735 | +21.8% | 1,196,298 | 0.0% | 5.84% | +70.8% | |
| Sell | PEAR THERAPEUTICS INC | $19,758,053 | -42.7% | 16,744,113 | -0.9% | 5.31% | -19.6% | |
| SCPH | Sell | SCPHARMACEUTICALS INC | $19,608,889 | -9.8% | 2,734,852 | -18.0% | 5.27% | +26.5% |
| CRNX | CRINETICS PHARMACEUTICALS IN | $15,779,834 | -6.8% | 862,286 | 0.0% | 4.24% | +30.7% | |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $14,768,665 | +131.6% | 665,555 | +70.4% | 3.97% | +224.8% |
| New | DISC MEDICINE INC | $11,704,111 | – | 588,442 | +100.0% | 3.14% | – | |
| ANAB | New | ANAPTYSBIO INC | $11,086,146 | – | 357,733 | +100.0% | 2.98% | – |
| ARVN | Sell | ARVINAS INC | $10,947,200 | -38.5% | 320,000 | -20.0% | 2.94% | -13.7% |
| IMPL | IMPEL NEUROPHARMA INC | $10,817,966 | -23.0% | 2,884,791 | 0.0% | 2.91% | +8.0% | |
| COGT | COGENT BIOSCIENCES INC | $9,137,486 | -22.5% | 790,440 | 0.0% | 2.46% | +8.7% | |
| VRDN | Sell | VIRIDIAN THERAPEUTICS INC | $8,763,000 | -11.9% | 300,000 | -38.1% | 2.36% | +23.6% |
| ISEE | Sell | IVERIC BIO INC | $8,234,843 | -9.8% | 384,626 | -24.4% | 2.21% | +26.5% |
| PHVS | PHARVARIS N V | $6,610,500 | +46.7% | 587,600 | 0.0% | 1.78% | +105.8% | |
| JANX | JANUX THERAPEUTICS INC | $5,877,323 | -2.7% | 446,266 | 0.0% | 1.58% | +36.4% | |
| FIXX | HOMOLOGY MEDICINES INC | $5,715,258 | -21.7% | 4,535,919 | 0.0% | 1.54% | +9.8% | |
| FGEN | New | FIBROGEN INC | $3,613,840 | – | 225,583 | +100.0% | 0.97% | – |
| CDTX | CIDARA THERAPEUTICS INC | $858,031 | +20.5% | 1,134,511 | 0.0% | 0.23% | +69.9% | |
| GMTX | Exit | GEMINI THERAPEUTICS INC | $0 | – | -524,500 | -100.0% | -0.16% | – |
| FVAM | Exit | 5 01 ACQUISITION CORP | $0 | – | -365,126 | -100.0% | -0.70% | – |
| AKUS | Exit | AKOUOS INC | $0 | – | -4,135,784 | -100.0% | -5.36% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| HOMOLOGY MEDICINES INC | 16 | Q3 2023 | 26.6% |
| ARVINAS INC | 16 | Q3 2023 | 14.3% |
| Crinetics Pharmaceuticals, Inc. | 16 | Q3 2023 | 12.8% |
| SCPHARMACEUTICALS INC | 16 | Q3 2023 | 7.5% |
| CIDARA THERAPEUTICS INC | 16 | Q3 2023 | 1.7% |
| IDEAYA BIOSCIENCES INC | 14 | Q1 2023 | 11.4% |
| VOR BIOPHARMA INC | 11 | Q3 2023 | 51.9% |
| CABALETTA BIO INC | 11 | Q2 2022 | 14.2% |
| AKOUOS INC | 10 | Q3 2022 | 27.7% |
| IMPEL PHARMACEUTICALS INC | 10 | Q3 2023 | 7.1% |
View 5AM Venture Management, LLC's complete holdings history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-14 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-15 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-03 |
| 13F-HR | 2021-11-15 |
View 5AM Venture Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.