$4.62 Billion is the total value of Avidity Partners Management LP's 85 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 51.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| XBI | New | SPDR SER TRcall | $337,146,000 | – | 4,062,000 | +100.0% | 7.30% | – |
| ARGX | Buy | ARGENX SEsponsored adr | $236,768,750 | +36.4% | 625,000 | +27.1% | 5.13% | +45.3% |
| UTHR | Sell | UNITED THERAPEUTICS CORP DEL | $218,439,695 | +7.5% | 785,500 | -19.0% | 4.73% | +14.6% |
| NBIX | Sell | NEUROCRINE BIOSCIENCES INC | $212,603,200 | +7.9% | 1,780,000 | -4.1% | 4.61% | +14.9% |
| AKRO | Buy | AKERO THERAPEUTICS INC | $209,610,000 | +97.2% | 3,825,000 | +22.5% | 4.54% | +110.1% |
| PRTA | Buy | PROTHENA CORP PLC | $177,918,250 | +49.2% | 2,953,000 | +50.1% | 3.85% | +58.9% |
| ARVN | Buy | ARVINAS INC | $169,339,500 | -12.4% | 4,950,000 | +14.0% | 3.67% | -6.6% |
| BSX | Buy | BOSTON SCIENTIFIC CORP | $150,687,509 | +53.3% | 3,256,700 | +28.3% | 3.26% | +63.3% |
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $149,162,450 | +11.1% | 5,861,000 | +4.9% | 3.23% | +18.4% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $138,526,700 | +63.1% | 2,990,000 | +45.7% | 3.00% | +73.8% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $136,706,900 | +30.4% | 1,055,000 | +11.3% | 2.96% | +39.0% |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $124,807,500 | – | 430,000 | +100.0% | 2.70% | – |
| UHS | New | UNIVERSAL HLTH SVCS INCcl b | $116,318,784 | – | 825,600 | +100.0% | 2.52% | – |
| JAZZ | Buy | JAZZ PHARMACEUTICALS PLC | $115,904,557 | +173.2% | 727,541 | +128.6% | 2.51% | +191.0% |
| ZNTL | Buy | ZENTALIS PHARMACEUTICALS INC | $103,721,000 | +13.4% | 5,150,000 | +21.9% | 2.25% | +20.8% |
| ACHC | Sell | ACADIA HEALTHCARE COMPANY IN | $95,902,800 | -11.7% | 1,165,000 | -16.1% | 2.08% | -5.9% |
| SGRY | Buy | SURGERY PARTNERS INC | $86,700,320 | +1284.5% | 3,112,000 | +1062.9% | 1.88% | +1378.7% |
| DXCM | Buy | DEXCOM INC | $85,700,032 | +127.6% | 756,800 | +61.8% | 1.86% | +142.4% |
| AZN | Buy | ASTRAZENECA PLCsponsored adr | $81,360,000 | +163.4% | 1,200,000 | +113.1% | 1.76% | +180.7% |
| LLY | Sell | LILLY ELI & CO | $79,387,280 | -75.6% | 217,000 | -78.5% | 1.72% | -74.0% |
| PCVX | Buy | VAXCYTE INC | $77,458,430 | +413.3% | 1,615,400 | +156.9% | 1.68% | +446.6% |
| RNA | Buy | AVIDITY BIOSCIENCES INC | $72,672,250 | +71.2% | 3,275,000 | +26.0% | 1.57% | +82.4% |
| NTRA | Buy | NATERA INC | $72,261,813 | -5.0% | 1,798,900 | +3.7% | 1.56% | +1.2% |
| IDYA | Buy | IDEAYA BIOSCIENCES INC | $69,496,616 | +25.4% | 3,824,800 | +2.9% | 1.51% | +33.6% |
| IMCR | Sell | IMMUNOCORE HLDGS PLCads | $65,858,780 | -32.5% | 1,154,000 | -44.5% | 1.43% | -28.1% |
| ALT | Buy | ALTIMMUNE INC | $65,635,500 | +91.5% | 3,990,000 | +48.7% | 1.42% | +104.0% |
| RVMD | Buy | REVOLUTION MEDICINES INC | $58,954,500 | +28.8% | 2,475,000 | +6.6% | 1.28% | +37.2% |
| KRTX | Sell | KARUNA THERAPEUTICS INC | $58,753,500 | -39.5% | 299,000 | -30.8% | 1.27% | -35.5% |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS IN | $55,770,000 | +34.4% | 1,375,000 | +9.5% | 1.21% | +43.1% |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $51,677,100 | -24.7% | 670,000 | -56.5% | 1.12% | -19.8% |
| VRTX | Sell | VERTEX PHARMACEUTICALS INC | $49,670,160 | -66.5% | 172,000 | -66.5% | 1.08% | -64.4% |
| LEGN | New | LEGEND BIOTECH CORPsponsored ads | $48,422,400 | – | 970,000 | +100.0% | 1.05% | – |
| KZR | Buy | KEZAR LIFE SCIENCES INC | $47,748,096 | +2.4% | 6,782,400 | +25.3% | 1.03% | +9.1% |
| PLRX | Buy | PLIANT THERAPEUTICS INC | $43,306,932 | +4.6% | 2,240,400 | +13.1% | 0.94% | +11.5% |
| New | VENTYX BIOSCIENCES INC | $42,135,150 | – | 1,285,000 | +100.0% | 0.91% | – | |
| ICLR | New | ICON PLC | $41,763,750 | – | 215,000 | +100.0% | 0.90% | – |
| DGX | New | QUEST DIAGNOSTICS INC | $40,361,520 | – | 258,000 | +100.0% | 0.87% | – |
| BIO | Sell | BIO RAD LABS INCcl a | $38,769,178 | -35.8% | 92,200 | -36.3% | 0.84% | -31.6% |
| BLU | Buy | BELLUS HEALTH INC NEW | $37,811,984 | -17.6% | 4,599,998 | +5.8% | 0.82% | -12.2% |
| THC | New | TENET HEALTHCARE CORP | $34,997,067 | – | 717,300 | +100.0% | 0.76% | – |
| KPTI | New | KARYOPHARM THERAPEUTICS INC | $32,755,297 | – | 9,633,911 | +100.0% | 0.71% | – |
| BNTX | New | BIONTECH SEsponsored ads | $32,357,388 | – | 215,400 | +100.0% | 0.70% | – |
| VERV | Buy | VERVE THERAPEUTICS INC | $30,282,750 | -15.5% | 1,565,000 | +50.1% | 0.66% | -9.9% |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $29,885,093 | – | 1,527,087 | +100.0% | 0.65% | – |
| ITCI | Sell | INTRA-CELLULAR THERAPIES INC | $26,671,680 | -59.1% | 504,000 | -64.1% | 0.58% | -56.4% |
| ARQT | Buy | ARCUTIS BIOTHERAPEUTICS INC | $25,974,000 | +71.1% | 1,755,000 | +120.9% | 0.56% | +82.2% |
| RXDX | New | PROMETHEUS BIOSCIENCES INC | $22,440,000 | – | 204,000 | +100.0% | 0.49% | – |
| NTLA | Sell | INTELLIA THERAPEUTICS INC | $22,266,798 | -60.2% | 638,200 | -36.1% | 0.48% | -57.6% |
| VIR | New | VIR BIOTECHNOLOGY INC | $21,513,500 | – | 850,000 | +100.0% | 0.47% | – |
| PHAT | Sell | PHATHOM PHARMACEUTICALS INC | $21,318,000 | +0.9% | 1,900,000 | -0.4% | 0.46% | +7.4% |
| New | BIOHAVEN LTD | $20,708,960 | – | 1,492,000 | +100.0% | 0.45% | – | |
| CYTK | Buy | CYTOKINETICS INC | $19,276,474 | +18.8% | 420,700 | +25.6% | 0.42% | +26.7% |
| DCPH | Sell | DECIPHERA PHARMACEUTICALS IN | $18,455,140 | -16.3% | 1,126,000 | -5.5% | 0.40% | -10.7% |
| Sell | CARIBOU BIOSCIENCES INC | $18,102,728 | -45.9% | 2,882,600 | -9.1% | 0.39% | -42.4% | |
| ISEE | New | IVERIC BIO INC | $17,950,294 | – | 838,407 | +100.0% | 0.39% | – |
| PNT | Sell | POINT BIOPHARMA GLOBAL INC | $17,732,196 | -18.7% | 2,432,400 | -13.7% | 0.38% | -13.3% |
| NSTG | Buy | NANOSTRING TECHNOLOGIES INC | $16,395,884 | +83.9% | 2,057,200 | +194.6% | 0.36% | +96.1% |
| TWST | New | TWIST BIOSCIENCE CORP | $14,547,910 | – | 611,000 | +100.0% | 0.32% | – |
| BCAB | New | BIOATLA INC | $10,395,000 | – | 1,260,000 | +100.0% | 0.22% | – |
| CMPX | COMPASS THERAPEUTICS INC | $10,060,000 | +120.6% | 2,000,000 | 0.0% | 0.22% | +134.4% | |
| SGMO | Buy | SANGAMO THERAPEUTICS INC | $8,629,662 | -25.4% | 2,748,300 | +16.4% | 0.19% | -20.4% |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $7,557,270 | +5.1% | 1,028,200 | +3.0% | 0.16% | +12.3% |
| KNTE | Buy | KINNATE BIOPHARMA INC | $7,397,470 | -49.0% | 1,212,700 | +0.0% | 0.16% | -45.8% |
| Buy | AN2 THERAPEUTICS INC | $7,086,508 | -45.1% | 743,600 | +0.1% | 0.15% | -41.2% | |
| IPSC | CENTURY THERAPEUTICS INC | $6,687,468 | -48.1% | 1,303,600 | 0.0% | 0.14% | -44.7% | |
| GRPH | GRAPHITE BIO INC | $5,229,000 | +4.7% | 1,575,000 | 0.0% | 0.11% | +10.8% | |
| MSAC | MEDICUS SCIENCES ACQUISITION | $5,236,400 | +1.7% | 520,000 | 0.0% | 0.11% | +7.6% | |
| ARYD | ARYA SCIENCES ACQU CORP IVcl a | $5,050,000 | +1.9% | 500,000 | 0.0% | 0.11% | +7.9% | |
| PANA | PANACEA ACQUISITION CORP II | $5,025,000 | +2.6% | 500,000 | 0.0% | 0.11% | +9.0% | |
| EPIX | Sell | ESSA PHARMA INC | $4,675,608 | +4.4% | 1,855,400 | -24.6% | 0.10% | +11.0% |
| HSAQ | HEALTH SCIENCES ACQ CORP 2 | $3,992,000 | +0.8% | 400,000 | 0.0% | 0.09% | +6.2% | |
| SYROS PHARMACEUTICALS INC | $3,231,000 | -44.3% | 900,000 | 0.0% | 0.07% | -40.7% | ||
| CYT | Sell | CYTEIR THERAPEUTICS INC | $2,963,070 | -14.6% | 1,795,800 | -0.6% | 0.06% | -9.9% |
| CMAX | CAREMAX INC | $2,756,951 | -48.5% | 755,329 | 0.0% | 0.06% | -45.0% | |
| DNAB | SOCIAL CAP SUVRETTA HLDS CRP | $2,012,000 | +2.7% | 200,000 | 0.0% | 0.04% | +10.0% | |
| DNAD | SOCIAL CAP SUVRETTA HLDS CP | $2,010,000 | +2.3% | 200,000 | 0.0% | 0.04% | +10.0% | |
| SCYX | SCYNEXIS INC | $1,779,336 | -35.0% | 1,140,600 | 0.0% | 0.04% | -30.4% | |
| HYPERFINE INC | $1,263,153 | +3.7% | 1,503,754 | 0.0% | 0.03% | +8.0% | ||
| FATE | New | FATE THERAPEUTICS INC | $1,055,949 | – | 104,653 | +100.0% | 0.02% | – |
| ZLAB | Sell | ZAI LAB LTDadr | $961,186 | -97.7% | 31,309 | -97.5% | 0.02% | -97.6% |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $879,234 | – | 37,898 | +100.0% | 0.02% | – |
| ACIU | Buy | AC IMMUNE SA | $663,816 | -23.6% | 325,400 | +18.4% | 0.01% | -22.2% |
| Sell | REUNION NEUROSCIENCE INC | $504,270 | -40.7% | 560,300 | -5.9% | 0.01% | -35.3% | |
| MSACW | MEDICUS SCIENCES ACQUISITION*w exp 02/12/202 | $5,199 | +419.9% | 57,770 | 0.0% | 0.00% | – | |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $14,450 | -19.7% | 99,999 | 0.0% | 0.00% | – | |
| Exit | SCIENCE 37 HOLDINGS INC | $0 | – | -430,000 | -100.0% | -0.01% | – | |
| PHAS | Exit | PHASEBIO PHARMACEUTICALS INC | $0 | – | -4,361,365 | -100.0% | -0.02% | – |
| Exit | SEMA4 HOLDINGS CORP | $0 | – | -950,000 | -100.0% | -0.02% | – | |
| ONCS | Exit | ONCOSEC MED INC | $0 | – | -2,945,000 | -100.0% | -0.03% | – |
| Exit | TANGO THERAPEUTICS INC | $0 | – | -813,700 | -100.0% | -0.06% | – | |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -500,000 | -100.0% | -0.10% | – |
| Exit | ERASCA INC | $0 | – | -982,500 | -100.0% | -0.16% | – | |
| SPNE | Exit | SEASPINE HLDGS CORP | $0 | – | -2,010,000 | -100.0% | -0.23% | – |
| STOK | Exit | STOKE THERAPEUTICS INC | $0 | – | -891,100 | -100.0% | -0.23% | – |
| TMDX | Exit | TRANSMEDICS GROUP INC | $0 | – | -300,000 | -100.0% | -0.26% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -1,382,900 | -100.0% | -0.27% | – |
| ATEC | Exit | ALPHATEC HLDGS INC | $0 | – | -1,715,000 | -100.0% | -0.30% | – |
| GOSS | Exit | GOSSAMER BIO INC | $0 | – | -1,450,000 | -100.0% | -0.35% | – |
| SIBN | Exit | SI-BONE INC | $0 | – | -996,700 | -100.0% | -0.35% | – |
| BGNE | Exit | BEIGENE LTDsponsored adr | $0 | – | -132,000 | -100.0% | -0.36% | – |
| NKTX | Exit | NKARTA INC | $0 | – | -1,414,082 | -100.0% | -0.38% | – |
| COGT | Exit | COGENT BIOSCIENCES INC | $0 | – | -1,357,700 | -100.0% | -0.41% | – |
| NGM | Exit | NGM BIOPHARMACEUTICALS INC | $0 | – | -1,798,100 | -100.0% | -0.48% | – |
| CNC | Exit | CENTENE CORP DEL | $0 | – | -432,400 | -100.0% | -0.68% | – |
| SYK | Exit | STRYKER CORPORATION | $0 | – | -184,700 | -100.0% | -0.76% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -844,000 | -100.0% | -1.17% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -288,500 | -100.0% | -1.17% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -445,500 | -100.0% | -1.24% | – |
| CTLT | Exit | CATALENT INC | $0 | – | -940,000 | -100.0% | -1.38% | – |
| AVTR | Exit | AVANTOR INC | $0 | – | -4,522,600 | -100.0% | -1.80% | – |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -1,482,200 | -100.0% | -1.86% | – |
| ANTM | Exit | ELEVANCE HEALTH INC | $0 | – | -207,600 | -100.0% | -1.92% | – |
| HUM | Exit | HUMANA INC | $0 | – | -212,000 | -100.0% | -2.09% | – |
| XBI | Exit | SPDR SER TRs&p biotech | $0 | – | -1,480,000 | -100.0% | -2.39% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -600,000 | -100.0% | -3.26% | – |
| Exit | SPDR SER TRcall | $0 | – | -4,052,000 | -100.0% | -6.53% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| NEUROCRINE BIOSCIENCES INC | 15 | Q3 2023 | 4.6% |
| ARVINAS INC | 14 | Q3 2023 | 4.9% |
| ZENTALIS PHARMACEUTICALS INC | 14 | Q3 2023 | 4.8% |
| SYNDAX PHARMACEUTICALS INC | 14 | Q3 2023 | 3.2% |
| IDEAYA BIOSCIENCES INC | 13 | Q3 2023 | 2.5% |
| NATERA INC | 13 | Q3 2023 | 1.9% |
| ALPINE IMMUNE SCIENCES INC | 13 | Q3 2023 | 0.5% |
| ABBVIE INC | 12 | Q2 2023 | 9.7% |
| HORIZON THERAPEUTICS PUB LTD | 12 | Q3 2022 | 3.4% |
| AVANTOR INC | 11 | Q1 2023 | 6.0% |
View Avidity Partners Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adicet Bio, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ALPINE IMMUNE SCIENCES, INC. | February 14, 2023 | 1,888,887 | 4.0% |
| ESSA Pharma Inc. | February 14, 2023 | 1,855,400 | 4.2% |
| Gritstone bio, Inc. | February 14, 2023 | 2,859,971 | 3.3% |
| IVERIC bio, Inc. | February 14, 2023 | 838,407 | 0.6% |
| ONCOSEC MEDICAL IncSold out | February 14, 2023 | 0 | 0.0% |
| PhaseBio Pharmaceuticals Inc | February 14, 2023 | 2,040,000 | 4.1% |
| Phathom Pharmaceuticals, Inc. | February 14, 2023 | 1,900,000 | 4.6% |
| Viridian Therapeutics, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Anika Therapeutics, Inc.Sold out | February 14, 2022 | 0 | 0.0% |
View Avidity Partners Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-09 |
| SC 13G | 2024-03-27 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
| SC 13G/A | 2024-02-13 |
View Avidity Partners Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.