$2.18 Billion is the total value of Avoro Capital Advisors LLC's 46 reported holdings in Q3 2018. The portfolio turnover from Q2 2018 to Q3 2018 was 40.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IMMU | IMMUNOMEDICS INC | $368,992,000 | -12.0% | 17,714,461 | 0.0% | 16.94% | +5.0% | |
| MRTX | MIRATI THERAPEUTICS INC | $225,991,000 | -4.5% | 4,798,101 | 0.0% | 10.38% | +14.0% | |
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $152,385,000 | +20.2% | 943,500 | -1.6% | 7.00% | +43.4% |
| ASND | Sell | ASCENDIS PHARMAsponsored adr | $139,122,000 | +1.4% | 1,963,336 | -4.8% | 6.39% | +20.9% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $132,665,000 | -13.2% | 1,368,103 | -15.7% | 6.09% | +3.5% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $112,838,000 | -22.9% | 9,333,132 | -0.4% | 5.18% | -8.0% |
| MDGL | Sell | MADRIGAL PHARMACEUTICALS INC | $99,142,000 | -27.6% | 463,000 | -5.4% | 4.55% | -13.6% |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $97,456,000 | -6.9% | 8,662,720 | +5.9% | 4.48% | +11.0% |
| ECYT | Sell | ENDOCYTE INC | $94,159,000 | +19.8% | 5,301,718 | -6.9% | 4.32% | +42.9% |
| HZNP | Sell | HORIZON PHARMA PLC | $87,335,000 | -5.7% | 4,460,426 | -20.3% | 4.01% | +12.5% |
| ZGNX | Sell | ZOGENIX INC | $72,312,000 | +8.8% | 1,457,913 | -3.0% | 3.32% | +29.8% |
| AMRN | New | AMARIN CORP PLCsponsored adr | $65,812,000 | – | 4,045,000 | +100.0% | 3.02% | – |
| ARGX | Sell | ARGENX SEsponsored adr | $57,291,000 | -11.6% | 755,415 | -3.4% | 2.63% | +5.5% |
| TCDA | Buy | TRICIDA INC | $54,119,000 | +65.2% | 1,771,500 | +61.7% | 2.48% | +97.1% |
| PBYI | Buy | PUMA BIOTECHNOLOGY INC | $52,759,000 | -13.8% | 1,150,685 | +11.2% | 2.42% | +2.9% |
| ASMB | Buy | ASSEMBLY BIOSCIENCES INC | $38,939,000 | +3.1% | 1,048,427 | +8.8% | 1.79% | +23.0% |
| CLVS | Buy | CLOVIS ONCOLOGY INC | $33,677,000 | -35.4% | 1,146,636 | +0.0% | 1.55% | -23.0% |
| PTCT | Sell | PTC THERAPEUTICS INC | $32,148,000 | -58.5% | 684,000 | -70.2% | 1.48% | -50.5% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $31,247,000 | +182.5% | 2,367,218 | +96.9% | 1.44% | +236.9% |
| TGTX | Sell | TG THERAPEUTICS INC | $23,520,000 | -63.9% | 4,200,031 | -15.2% | 1.08% | -56.9% |
| TLGT | TELIGENT INC | $20,933,000 | +14.2% | 5,299,431 | 0.0% | 0.96% | +36.1% | |
| PCRX | Sell | PACIRA PHARMACEUTICALS INC | $20,309,000 | -56.6% | 413,196 | -71.7% | 0.93% | -48.2% |
| CPRX | CATALYST PHARMACEUTICALS INC | $16,999,000 | +21.2% | 4,497,042 | 0.0% | 0.78% | +44.6% | |
| ARWR | Buy | ARROWHEAD PHARMACEUTICALS INC | $16,293,000 | +166.2% | 849,899 | +88.9% | 0.75% | +216.9% |
| BDSI | BIODELIVERY SCIENCES INTL | $15,226,000 | -5.1% | 5,437,779 | 0.0% | 0.70% | +13.1% | |
| SESN | SESEN BIO INC | $14,620,000 | +10.3% | 6,800,000 | 0.0% | 0.67% | +31.6% | |
| INTEC PHARMA LTD | $14,524,000 | +28.4% | 2,570,705 | 0.0% | 0.67% | +53.3% | ||
| ESTA | New | ESTABLISHMENT LABS HOLDINGS INC | $11,448,000 | – | 475,000 | +100.0% | 0.53% | – |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS INC | $10,925,000 | -65.5% | 287,500 | -59.0% | 0.50% | -58.8% |
| VNDA | Sell | VANDA PHARMACEUTICALS INC | $9,869,000 | -81.5% | 430,000 | -84.6% | 0.45% | -77.9% |
| ACER | New | ACER THERAPEUTICS INC | $8,635,000 | – | 280,000 | +100.0% | 0.40% | – |
| FENC | FENNEC PHARMACEUTICALS INC | $8,386,000 | -21.6% | 1,022,666 | 0.0% | 0.38% | -6.6% | |
| YMAB | New | Y MABS THERAPEUTICS INC | $8,234,000 | – | 310,000 | +100.0% | 0.38% | – |
| CRSP | New | CRISPR THERAPEUTICS AG | $6,536,000 | – | 147,368 | +100.0% | 0.30% | – |
| ALIM | ALIMERA SCIENCES INC | $6,117,000 | +0.2% | 6,241,581 | 0.0% | 0.28% | +19.6% | |
| TSRO | New | TESARO INC | $5,852,000 | – | 150,000 | +100.0% | 0.27% | – |
| PERNIX THERAPEUTICS HOLDINGS INCconvertible debt | $2,628,000 | +0.4% | 6,000,000 | 0.0% | 0.12% | +19.8% | ||
| PRNB | New | PRINCIPIA BIOPHARMA INC | $2,192,000 | – | 75,000 | +100.0% | 0.10% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $2,076,000 | – | 100,000 | +100.0% | 0.10% | – |
| DBVT | New | DBV TECHNOLOGIES SAsponsored adr | $1,213,000 | – | 54,000 | +100.0% | 0.06% | – |
| XBI | Sell | SPDR SERIES TRUST - S&P BIOTECHput | $1,180,000 | -77.7% | 1,500,000 | -14.3% | 0.05% | -73.5% |
| ONCS | Sell | ONCOSEC MEDICAL INC | $700,000 | -87.3% | 500,000 | -87.5% | 0.03% | -85.0% |
| ONS | ONCOBIOLOGICS INC | $670,000 | +15.9% | 683,531 | 0.0% | 0.03% | +40.9% | |
| QQQ | New | INVESCO QQQ TRUSTput | $175,000 | – | 500,000 | +100.0% | 0.01% | – |
| ONSIW | ONCOBIOLOGICS INC - WARRANT Awarrant | $3,000 | -75.0% | 233,333 | 0.0% | 0.00% | – | |
| AVRO | Exit | AVROBIO INC | $0 | – | -100,000 | -100.0% | -0.11% | – |
| DERM | Exit | DERMIRA INC | $0 | – | -1,841,823 | -100.0% | -0.65% | – |
| CBAY | Exit | CYMABAY THERAPEUTICS INC | $0 | – | -1,282,374 | -100.0% | -0.66% | – |
| MDCO | Exit | MEDICINES CO | $0 | – | -961,574 | -100.0% | -1.36% | – |
| VKTX | Exit | VIKING THERAPEUTICS INC | $0 | – | -4,471,300 | -100.0% | -1.63% | – |
| ALNY | Exit | ALNYLAM PHARMACEUTICALS INC | $0 | – | -700,100 | -100.0% | -2.65% | – |
| SPPI | Exit | SPECTRUM PHARMACEUTICALS INC | $0 | – | -3,419,818 | -100.0% | -2.76% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2018-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| AMICUS THERAPEUTICS INC | 36 | Q3 2023 | 17.9% |
| MIRATI THERAPEUTICS INC. | 35 | Q3 2023 | 17.2% |
| BIOMARIN PHARMACEUTICAL INC | 31 | Q3 2023 | 8.0% |
| SAREPTA THERAPUTICS INC | 28 | Q3 2023 | 14.8% |
| ASCENDIS PHARMA | 28 | Q3 2023 | 9.1% |
| ARGENX SE | 26 | Q3 2023 | 9.5% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
| FENNEC PHARMACEUTICALS INC | 25 | Q3 2023 | 0.4% |
| MADRIGAL PHARMACEUTICALS INC | 22 | Q3 2023 | 7.2% |
| XENON PHARMACEUTICALS INC | 22 | Q3 2023 | 3.3% |
View Avoro Capital Advisors LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| DICE Therapeutics, Inc. | February 14, 2023 | 2,525,555 | 5.3% |
| IOVANCE BIOTHERAPEUTICS, INC. | February 14, 2023 | 7,020,000 | 4.4% |
| IVERIC bio, Inc. | February 14, 2023 | 6,750,000 | 5.0% |
| Kura Oncology, Inc. | February 14, 2023 | 3,105,000 | 4.5% |
| Aadi Bioscience, Inc. | September 26, 2022 | 2,849,402 | 11.7% |
| ARENA PHARMACEUTICALS INC | February 11, 2022 | 1,235,000 | 2.0% |
| AVADEL PHARMACEUTICALS PLC | February 11, 2022 | 1,670,000 | 2.9% |
| FENNEC PHARMACEUTICALS INC. | February 11, 2022 | 1,200,000 | 4.6% |
| POINT Biopharma Global Inc.Sold out | February 11, 2022 | 0 | 0.0% |
View Avoro Capital Advisors LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-23 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Avoro Capital Advisors LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.