$2.6 Billion is the total value of Avoro Capital Advisors LLC's 44 reported holdings in Q2 2018. The portfolio turnover from Q1 2018 to Q2 2018 was 67.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IMMU | Buy | IMMUNOMEDICS INC | $419,301,000 | +69.4% | 17,714,461 | +4.6% | 16.14% | +36.6% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $236,546,000 | +75.2% | 4,798,101 | +9.1% | 9.11% | +41.2% |
| BMRN | Sell | BIOMARIN PHARMACEUTICAL INC | $152,865,000 | +10.2% | 1,622,770 | -5.2% | 5.88% | -11.2% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $146,346,000 | +2.4% | 9,369,150 | -1.4% | 5.63% | -17.5% |
| ASND | ASCENDIS PHARMAsponsored adr | $137,253,000 | +1.7% | 2,063,336 | 0.0% | 5.28% | -18.0% | |
| MDGL | New | MADRIGAL PHARMACEUTICALS INC | $136,918,000 | – | 489,536 | +100.0% | 5.27% | – |
| SRPT | New | SAREPTA THERAPEUTICS INC | $126,751,000 | – | 958,928 | +100.0% | 4.88% | – |
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $104,675,000 | -23.3% | 8,177,720 | +1.2% | 4.03% | -38.2% |
| HZNP | Buy | HORIZON PHARMA PLC | $92,631,000 | +26.5% | 5,593,683 | +8.4% | 3.57% | +1.9% |
| ECYT | ENDOCYTE INC | $78,594,000 | +51.8% | 5,695,200 | 0.0% | 3.03% | +22.4% | |
| PTCT | New | PTC THERAPEUTICS INC | $77,406,000 | – | 2,294,877 | +100.0% | 2.98% | – |
| SPPI | New | SPECTRUM PHARMACEUTICALS INC | $71,679,000 | – | 3,419,818 | +100.0% | 2.76% | – |
| ALNY | New | ALNYLAM PHARMACEUTICALS INC | $68,953,000 | – | 700,100 | +100.0% | 2.65% | – |
| ZGNX | Buy | ZOGENIX INC | $66,446,000 | +39.5% | 1,503,313 | +26.4% | 2.56% | +12.5% |
| TGTX | Sell | TG THERAPEUTICS INC | $65,093,000 | -12.3% | 4,950,031 | -5.3% | 2.51% | -29.3% |
| ARGX | Sell | ARGENX SEsponsored adr | $64,801,000 | -6.7% | 782,053 | -9.4% | 2.50% | -24.8% |
| PBYI | Buy | PUMA BIOTECHNOLOGY INC | $61,183,000 | +8.9% | 1,034,375 | +25.3% | 2.36% | -12.2% |
| VNDA | Buy | VANDA PHARMACEUTICALS INC | $53,344,000 | +14.1% | 2,800,191 | +0.9% | 2.05% | -8.0% |
| CLVS | Sell | CLOVIS ONCOLOGY INC | $52,128,000 | -15.3% | 1,146,436 | -1.7% | 2.01% | -31.7% |
| PCRX | Sell | PACIRA PHARMACEUTICALS INC | $46,813,000 | -12.4% | 1,460,610 | -14.8% | 1.80% | -29.4% |
| VKTX | New | VIKING THERAPEUTICS INC | $42,433,000 | – | 4,471,300 | +100.0% | 1.63% | – |
| ASMB | Sell | ASSEMBLY BIOSCIENCES INC | $37,776,000 | -29.7% | 963,427 | -11.9% | 1.45% | -43.4% |
| MDCO | Sell | MEDICINES CO | $35,290,000 | -34.5% | 961,574 | -41.2% | 1.36% | -47.2% |
| TCDA | New | TRICIDA INC | $32,763,000 | – | 1,095,764 | +100.0% | 1.26% | – |
| GBT | Sell | GLOBAL BLOOD THERAPEUTICS INC | $31,665,000 | -62.9% | 700,548 | -60.3% | 1.22% | -70.1% |
| TLGT | TELIGENT INC | $18,336,000 | +3.0% | 5,299,431 | 0.0% | 0.71% | -16.9% | |
| CBAY | New | CYMABAY THERAPEUTICS INC | $17,209,000 | – | 1,282,374 | +100.0% | 0.66% | – |
| DERM | Sell | DERMIRA INC | $16,945,000 | -38.1% | 1,841,823 | -46.3% | 0.65% | -50.2% |
| BDSI | BIODELIVERY SCIENCES INTL | $16,041,000 | +31.1% | 5,437,779 | 0.0% | 0.62% | +5.8% | |
| CPRX | Sell | CATALYST PHARMACEUTICALS INC | $14,031,000 | +25.1% | 4,497,042 | -4.2% | 0.54% | +0.7% |
| SESN | New | SESEN BIO INC | $13,260,000 | – | 6,800,000 | +100.0% | 0.51% | – |
| Buy | INTEC PHARMA LTD | $11,311,000 | -18.9% | 2,570,705 | +17.1% | 0.44% | -34.7% | |
| XENE | New | XENON PHARMACEUTICALS INC | $11,059,000 | – | 1,202,118 | +100.0% | 0.43% | – |
| FENC | Buy | FENNEC PHARMACEUTICALS INC | $10,700,000 | +225.8% | 1,022,666 | +275.1% | 0.41% | +162.4% |
| ARWR | New | ARROWHEAD PHARMACEUTICALS INC | $6,120,000 | – | 450,000 | +100.0% | 0.24% | – |
| ALIM | ALIMERA SCIENCES INC | $6,106,000 | -5.0% | 6,241,581 | 0.0% | 0.24% | -23.5% | |
| ONCS | ONCOSEC MEDICAL INC | $5,531,000 | -26.6% | 4,007,696 | 0.0% | 0.21% | -40.8% | |
| XBI | Buy | SPDR SERIES TRUST - S&P BIOTECHput | $5,300,000 | +431.1% | 1,750,000 | +133.3% | 0.20% | +325.0% |
| AVRO | New | AVROBIO INC | $2,856,000 | – | 100,000 | +100.0% | 0.11% | – |
| PERNIX THERAPEUTICS HOLDINGS INCconvertible debt | $2,618,000 | -5.6% | 6,000,000 | 0.0% | 0.10% | -23.5% | ||
| ONS | ONCOBIOLOGICS INC | $578,000 | -4.9% | 683,531 | 0.0% | 0.02% | -24.1% | |
| ONSIW | ONCOBIOLOGICS INC - WARRANT Awarrant | $12,000 | +140.0% | 233,333 | 0.0% | 0.00% | – | |
| ONSIZ | Exit | ONCOBIOLOGICS INC - WARRANT Bwarrant | $0 | – | -233,333 | -100.0% | -0.00% | – |
| MGNX | Exit | MACROGENICS INCcall | $0 | – | -14,500 | -100.0% | -0.00% | – |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INCcall | $0 | – | -162,500 | -100.0% | -0.01% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INCcall | $0 | – | -500,000 | -100.0% | -0.02% | – |
| VCYT | Exit | VERACYTE INC | $0 | – | -119,680 | -100.0% | -0.03% | – |
| GBT | Exit | GLOBAL BLOOD THERAPEUTICS INCcall | $0 | – | -152,000 | -100.0% | -0.07% | – |
| QURE | Exit | UNIQURE NVshares | $0 | – | -67,758 | -100.0% | -0.08% | – |
| SLDB | Exit | SOLID BIOSCIENCES INC | $0 | – | -275,000 | -100.0% | -0.10% | – |
| AGEN | Exit | AGENUS INC | $0 | – | -704,554 | -100.0% | -0.16% | – |
| DOVA | Exit | DOVA PHARMACEUTICALS INC | $0 | – | -125,000 | -100.0% | -0.16% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INCcall | $0 | – | -2,350,100 | -100.0% | -0.18% | – |
| TNDM | Exit | TANDEM DIABETES CARE INC | $0 | – | -783,910 | -100.0% | -0.19% | – |
| VRAY | Exit | VIEWRAY INC | $0 | – | -730,161 | -100.0% | -0.19% | – |
| VIVE | Exit | VIVEVE MEDICAL INC | $0 | – | -1,533,276 | -100.0% | -0.27% | – |
| ACAD | Exit | ACADIA PHARMACEUTICALS INC | $0 | – | -317,100 | -100.0% | -0.34% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -396,635 | -100.0% | -0.36% | – |
| KPTI | Exit | KARYOPHARM THERAPEUTICS INC | $0 | – | -560,658 | -100.0% | -0.36% | – |
| STML | Exit | STEMLINE THERAPEUTICS INC | $0 | – | -524,321 | -100.0% | -0.38% | – |
| AVEO | Exit | AVEO PHARMACEUTICALS INC | $0 | – | -3,231,893 | -100.0% | -0.45% | – |
| JNCE | Exit | JOUNCE THERAPEUTICS INC | $0 | – | -523,174 | -100.0% | -0.56% | – |
| AZN | Exit | ASTRAZENECA PLCsponsored adr | $0 | – | -750,300 | -100.0% | -1.25% | – |
| CBIO | Exit | CATALYST BIOSCIENCES INC | $0 | – | -1,024,124 | -100.0% | -1.26% | – |
| ARRY | Exit | ARRAY BIOPHARMA INC | $0 | – | -1,922,655 | -100.0% | -1.50% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -1,650,700 | -100.0% | -1.56% | – |
| ARMO | Exit | ARMO BIOSCIENCES INC | $0 | – | -1,207,500 | -100.0% | -2.16% | – |
| AVXS | Exit | AVEXIS INC | $0 | – | -675,262 | -100.0% | -3.98% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2018-08-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| AMICUS THERAPEUTICS INC | 36 | Q3 2023 | 17.9% |
| MIRATI THERAPEUTICS INC. | 35 | Q3 2023 | 17.2% |
| BIOMARIN PHARMACEUTICAL INC | 31 | Q3 2023 | 8.0% |
| SAREPTA THERAPUTICS INC | 28 | Q3 2023 | 14.8% |
| ASCENDIS PHARMA | 28 | Q3 2023 | 9.1% |
| ARGENX SE | 26 | Q3 2023 | 9.5% |
| IOVANCE BIOTHERAPEUTICS INC | 26 | Q3 2023 | 9.1% |
| FENNEC PHARMACEUTICALS INC | 25 | Q3 2023 | 0.4% |
| MADRIGAL PHARMACEUTICALS INC | 22 | Q3 2023 | 7.2% |
| XENON PHARMACEUTICALS INC | 22 | Q3 2023 | 3.3% |
View Avoro Capital Advisors LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| DICE Therapeutics, Inc. | February 14, 2023 | 2,525,555 | 5.3% |
| IOVANCE BIOTHERAPEUTICS, INC. | February 14, 2023 | 7,020,000 | 4.4% |
| IVERIC bio, Inc. | February 14, 2023 | 6,750,000 | 5.0% |
| Kura Oncology, Inc. | February 14, 2023 | 3,105,000 | 4.5% |
| Aadi Bioscience, Inc. | September 26, 2022 | 2,849,402 | 11.7% |
| ARENA PHARMACEUTICALS INC | February 11, 2022 | 1,235,000 | 2.0% |
| AVADEL PHARMACEUTICALS PLC | February 11, 2022 | 1,670,000 | 2.9% |
| FENNEC PHARMACEUTICALS INC. | February 11, 2022 | 1,200,000 | 4.6% |
| POINT Biopharma Global Inc.Sold out | February 11, 2022 | 0 | 0.0% |
View Avoro Capital Advisors LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-23 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Avoro Capital Advisors LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.