$1.56 Billion is the total value of Sofinnova Investments, Inc.'s 53 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 56.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KRTX | Sell | Karuna Therapeutics Inc | $322,070,243 | -20.9% | 1,773,124 | -14.5% | 20.60% | -14.8% |
| NTRA | Natera Inc | $172,143,091 | +38.2% | 3,100,560 | 0.0% | 11.01% | +49.0% | |
| MRK | Buy | Merck & Co Inc | $89,529,526 | +33.7% | 841,522 | +39.5% | 5.73% | +44.2% |
| SPY | New | SPDR S&P 500 ETF Trustput | $81,878,000 | – | 200,000 | +100.0% | 5.24% | – |
| ASND | Sell | Ascendis Pharma A/Ssponsored adr | $80,847,311 | -24.8% | 754,032 | -14.4% | 5.17% | -19.0% |
| AVTE | Aerovate Therapeutics Inc | $75,812,697 | -31.2% | 3,758,686 | 0.0% | 4.85% | -25.8% | |
| RETA | Sell | Reata Pharmaceuticals Inccl a | $57,068,938 | +51.4% | 627,683 | -36.7% | 3.65% | +63.2% |
| LLY | New | Eli Lilly and Co | $47,082,882 | – | 137,100 | +100.0% | 3.01% | – |
| HZNP | Sell | Horizon Therapeutics PLC | $44,618,506 | -5.1% | 408,819 | -1.1% | 2.85% | +2.3% |
| ISRG | New | Intuitive Surgical Inc | $38,215,502 | – | 149,589 | +100.0% | 2.44% | – |
| BIIB | New | Biogen Inc | $36,866,778 | – | 132,600 | +100.0% | 2.36% | – |
| BMRN | Sell | Biomarin Pharmaceutical Inc | $34,912,563 | -14.5% | 359,035 | -9.0% | 2.23% | -7.9% |
| DXCM | Buy | Dexcom Inc | $29,884,633 | +87.6% | 257,227 | +82.8% | 1.91% | +102.2% |
| TVTX | Buy | Travere Therapeutics Inc | $28,421,085 | +133.7% | 1,263,721 | +118.5% | 1.82% | +151.8% |
| VERA | Buy | Vera Therapeutics Inccl a | $26,905,131 | -56.3% | 3,467,156 | +9.0% | 1.72% | -52.9% |
| PTCT | New | PTC Therapeutics Inc | $25,048,082 | – | 517,095 | +100.0% | 1.60% | – |
| ZNTL | Buy | Zentalis Pharmaceuticals Inc | $24,751,866 | +22.4% | 1,439,062 | +43.3% | 1.58% | +31.9% |
| INBX | Buy | Inhibrx Inc | $23,483,489 | -14.2% | 1,244,488 | +12.1% | 1.50% | -7.5% |
| KDNY | Buy | Chinook Therapeutics Inc | $23,204,356 | +9.8% | 1,002,348 | +24.3% | 1.48% | +18.3% |
| SNDX | Buy | Syndax Pharmaceuticals Inc | $22,712,955 | +26.9% | 1,075,424 | +53.0% | 1.45% | +36.8% |
| ISEE | Buy | IVERIC bio Inc | $22,042,542 | +61.3% | 905,982 | +41.9% | 1.41% | +73.9% |
| IMTX | Buy | Immatics NV | $21,615,589 | +24.0% | 3,132,694 | +56.6% | 1.38% | +33.7% |
| INZY | Inozyme Pharma Inc | $20,944,915 | +445.7% | 3,655,308 | 0.0% | 1.34% | +487.7% | |
| GERN | Buy | Geron Corp | $17,956,516 | +408.4% | 8,274,892 | +466.9% | 1.15% | +446.7% |
| SRPT | Sell | Sarepta Therapeutics Inc | $16,410,729 | -48.9% | 119,065 | -52.0% | 1.05% | -44.9% |
| EXEL | New | Exelixis Inc | $16,134,427 | – | 831,243 | +100.0% | 1.03% | – |
| VIR | New | Vir Biotechnology Inc | $15,301,398 | – | 657,559 | +100.0% | 0.98% | – |
| CLDX | New | Celldex Therapeutics Inc | $15,089,904 | – | 419,397 | +100.0% | 0.96% | – |
| RXDX | Sell | Prometheus Biosciences Inc | $13,290,723 | -31.6% | 123,842 | -29.9% | 0.85% | -26.2% |
| CYTK | Sell | Cytokinetics Inc | $12,450,081 | -46.6% | 353,796 | -30.5% | 0.80% | -42.5% |
| CTIC | Sell | CTI Biopharma Corp | $11,737,076 | -57.6% | 2,794,542 | -39.3% | 0.75% | -54.3% |
| YMAB | Y-mAbs Therapeutics Inc | $10,993,333 | +2.7% | 2,194,278 | 0.0% | 0.70% | +10.7% | |
| AGEN | Buy | Agenus Inc | $9,739,335 | +40.2% | 6,407,457 | +121.4% | 0.62% | +51.2% |
| New | Marinus Pharmaceuticals Inc | $8,282,684 | – | 1,200,389 | +100.0% | 0.53% | – | |
| GRTX | Galera Therapeutics Inc | $7,894,303 | +71.8% | 3,083,712 | 0.0% | 0.50% | +85.0% | |
| KURA | Buy | Kura Oncology Inc | $7,535,747 | +2.3% | 616,169 | +3.8% | 0.48% | +10.3% |
| AXSM | New | Axsome Therapeutics Inc | $7,456,865 | – | 120,896 | +100.0% | 0.48% | – |
| IDYA | Sell | IDEAYA Biosciences Inc | $6,221,736 | -27.8% | 453,149 | -4.5% | 0.40% | -22.3% |
| NCNA | Nucana PLCsponsored adr | $5,376,559 | +45.5% | 5,599,999 | 0.0% | 0.34% | +57.1% | |
| RVMD | New | Revolution Medicines Inc | $3,981,931 | – | 183,838 | +100.0% | 0.26% | – |
| NXTC | Nextcure Inc | $3,954,347 | +5.0% | 2,671,856 | 0.0% | 0.25% | +12.9% | |
| IMGN | New | ImmunoGen Inccall | $3,840,000 | – | 1,000,000 | +100.0% | 0.25% | – |
| BOLT | Bolt Biotherapeutics Inc | $3,828,667 | +6.9% | 2,754,437 | 0.0% | 0.24% | +15.6% | |
| IMGN | Sell | ImmunoGen Inc | $3,550,203 | -57.6% | 924,532 | -45.2% | 0.23% | -54.2% |
| KROS | New | Keros Therapeutics Inc | $3,292,170 | – | 77,100 | +100.0% | 0.21% | – |
| NVCR | New | Novocure Ltdcall | $3,007,000 | – | 50,000 | +100.0% | 0.19% | – |
| Nucana PLC | $2,304,240 | +45.5% | 2,400,000 | 0.0% | 0.15% | +56.4% | ||
| BLUE | New | bluebird bio Inc | $2,139,552 | – | 672,815 | +100.0% | 0.14% | – |
| PDSB | PDS Biotechnology Corp | $877,205 | -53.4% | 142,635 | 0.0% | 0.06% | -50.0% | |
| FUSN | Fusion Pharmaceuticals Inc | $441,463 | +19.7% | 117,099 | 0.0% | 0.03% | +27.3% | |
| SYBX | Synlogic Inc | $363,382 | -16.8% | 574,972 | 0.0% | 0.02% | -11.5% | |
| ALNY | Sell | Alnylam Pharmaceuticals Inc | $89,743 | -99.3% | 448 | -99.2% | 0.01% | -99.2% |
| OBSV | Exit | ObsEva SA | $0 | – | -4,749,623 | -100.0% | -0.04% | – |
| CTIC | Exit | CTI Biopharma Corpcall | $0 | – | -410,000 | -100.0% | -0.15% | – |
| AGEN | Exit | Agenus Inccall | $0 | – | -1,267,000 | -100.0% | -0.18% | – |
| CYTK | Exit | Cytokinetics Inccall | $0 | – | -100,000 | -100.0% | -0.27% | – |
| FULC | Exit | Fulcrum Therapeutics Inc | $0 | – | -631,411 | -100.0% | -0.27% | – |
| GERN | Exit | Geron Corpcall | $0 | – | -2,369,100 | -100.0% | -0.34% | – |
| RCUS | Exit | Arcus Biosciences Inc | $0 | – | -314,811 | -100.0% | -0.39% | – |
| ALGN | Exit | Align Technology Inc | $0 | – | -83,100 | -100.0% | -1.04% | – |
| ALNY | Exit | Alnylam Pharmaceuticals Inccall | $0 | – | -100,000 | -100.0% | -1.41% | – |
| UTHR | Exit | United Therapeutics Corp | $0 | – | -89,207 | -100.0% | -1.47% | – |
| AZN | Exit | AstraZeneca PLCsponsored adr | $0 | – | -613,673 | -100.0% | -2.47% | – |
| VRTX | Exit | Vertex Pharmaceuticals Inc | $0 | – | -156,989 | -100.0% | -2.69% | – |
| Exit | Cincor Pharma Inc | $0 | – | -6,073,949 | -100.0% | -4.43% | – | |
| SNY | Exit | Sanofi SAsponsored adr | $0 | – | -1,965,475 | -100.0% | -5.65% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-11
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.