$1.59 Billion is the total value of Sofinnova Investments, Inc.'s 69 reported holdings in Q3 2023. The portfolio turnover from Q2 2023 to Q3 2023 was 76.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KRTX | Karuna Therapeutics Inc | $233,538,484 | -22.0% | 1,381,149 | 0.0% | 14.73% | -24.9% | |
| NTRA | Natera Inc | $137,199,780 | -9.1% | 3,100,560 | 0.0% | 8.66% | -12.4% | |
| AZN | Sell | AstraZeneca PLCsponsored adr | $92,291,254 | -24.0% | 1,362,836 | -19.7% | 5.82% | -26.8% |
| MRK | Buy | Merck & Co Inc | $74,989,192 | +23.2% | 728,404 | +38.1% | 4.73% | +18.7% |
| ASND | Ascendis Pharma A/Ssponsored adr | $70,607,556 | +4.9% | 754,032 | 0.0% | 4.45% | +1.0% | |
| New | RayzeBio Inc | $53,713,522 | – | 2,419,528 | +100.0% | 3.39% | – | |
| DXCM | Buy | Dexcom Inc | $51,333,380 | +7.7% | 550,197 | +48.4% | 3.24% | +3.8% |
| AVTE | Aerovate Therapeutics Inc | $51,005,369 | -20.9% | 3,758,686 | 0.0% | 3.22% | -23.8% | |
| ISRG | Sell | Intuitive Surgical Inc | $50,647,134 | -26.4% | 173,277 | -13.9% | 3.20% | -29.1% |
| VERA | Vera Therapeutics Inccl a | $47,534,709 | -14.6% | 3,467,156 | 0.0% | 3.00% | -17.7% | |
| ELAN | New | Elanco Animal Health Inc | $40,576,670 | – | 3,610,024 | +100.0% | 2.56% | – |
| IWM | New | IShares TRput | $39,766,500 | – | 225,000 | +100.0% | 2.51% | – |
| ARGX | Buy | argenx SEsponsored adr | $38,438,583 | +147.1% | 78,186 | +95.9% | 2.42% | +138.0% |
| IMTX | Buy | Immatics NV | $37,652,474 | +7.3% | 3,251,509 | +6.9% | 2.38% | +3.3% |
| SNY | New | Sanofisponsored adr | $37,299,915 | – | 695,375 | +100.0% | 2.35% | – |
| New | Kenvue Inc | $36,185,847 | – | 1,802,084 | +100.0% | 2.28% | – | |
| IDXX | Buy | IDEXX Laboratories Inc | $34,055,025 | -4.1% | 77,881 | +10.2% | 2.15% | -7.6% |
| IMGN | Buy | ImmunoGen Inc | $32,457,356 | +107.9% | 2,045,202 | +147.2% | 2.05% | +100.1% |
| CYTK | Buy | Cytokinetics Inc | $31,232,431 | +13.5% | 1,060,164 | +25.7% | 1.97% | +9.3% |
| IDYA | Buy | IDEAYA Biosciences Inc | $27,983,305 | +79.1% | 1,037,187 | +56.0% | 1.76% | +72.5% |
| ZNTL | Buy | Zentalis Pharmaceuticals Inc | $24,305,518 | +4.1% | 1,211,641 | +46.3% | 1.53% | +0.2% |
| SPY | New | SPDR S&P 500 ETF Trustput | $21,374,000 | – | 50,000 | +100.0% | 1.35% | – |
| EXEL | New | Exelixis Incput | $19,940,310 | – | 912,600 | +100.0% | 1.26% | – |
| EXEL | Sell | Exelixis Inc | $18,152,193 | -62.9% | 830,764 | -67.6% | 1.14% | -64.3% |
| INZY | Buy | Inozyme Pharma Inc | $17,977,294 | -11.7% | 4,280,308 | +17.1% | 1.13% | -15.0% |
| New | Invesco QQQ TRunit ser 1 | $17,913,500 | – | 50,000 | +100.0% | 1.13% | – | |
| New | MoonLake Immunotherapeuticsclass a ord | $16,689,885 | – | 292,805 | +100.0% | 1.05% | – | |
| New | Shockwave Med Inc | $16,201,364 | – | 81,373 | +100.0% | 1.02% | – | |
| AGEN | Buy | Agenus Inc | $15,102,165 | +92.3% | 13,364,748 | +172.2% | 0.95% | +85.4% |
| ALKS | New | Alkermes PLC | $15,054,367 | – | 537,464 | +100.0% | 0.95% | – |
| CYTK | New | Cytokinetics Incput | $14,730,000 | – | 500,000 | +100.0% | 0.93% | – |
| SNDX | Sell | Syndax Pharmaceuticals Inc | $13,675,183 | -58.7% | 941,817 | -40.5% | 0.86% | -60.2% |
| INBX | Sell | Inhibrx Inc | $13,639,445 | -47.4% | 743,294 | -25.5% | 0.86% | -49.3% |
| YMAB | Y-mAbs Therapeutics Inc | $11,958,815 | -19.7% | 2,194,278 | 0.0% | 0.75% | -22.7% | |
| CLDX | Buy | Celldex Therapeutics Inc | $11,675,608 | +74.0% | 424,259 | +114.5% | 0.74% | +67.9% |
| New | Structure Therapeutics Incsponsored ads | $10,190,840 | – | 202,119 | +100.0% | 0.64% | – | |
| CRSP | New | CRISPR Therapeutics AGput | $9,078,000 | – | 200,000 | +100.0% | 0.57% | – |
| SNDX | New | Syndax Pharmaceuticals Inccall | $8,712,000 | – | 600,000 | +100.0% | 0.55% | – |
| REPL | Buy | Replimune Group Inc | $8,620,771 | +6.4% | 503,844 | +44.4% | 0.54% | +2.4% |
| Buy | Marinus Pharmaceuticals Inc | $7,934,128 | -24.1% | 985,606 | +2.4% | 0.50% | -26.9% | |
| GERN | Sell | Geron Corp | $7,849,398 | -55.0% | 3,702,546 | -31.8% | 0.50% | -56.6% |
| SNDX | New | Syndax Pharmaceuticals Incput | $6,534,000 | – | 450,000 | +100.0% | 0.41% | – |
| SRPT | New | Sarepta Therapeutics Inccall | $6,194,342 | – | 51,100 | +100.0% | 0.39% | – |
| DYN | Buy | Dyne Therapeutics Inc | $6,138,792 | +23.7% | 685,133 | +55.3% | 0.39% | +19.1% |
| AXSM | Sell | Axsome Therapeutics Inc | $5,616,920 | -56.4% | 80,368 | -55.2% | 0.35% | -58.1% |
| CLDX | New | Celldex Therapeutics Incput | $5,504,000 | – | 200,000 | +100.0% | 0.35% | – |
| IMVT | New | Immunovant Inc | $5,370,185 | – | 139,885 | +100.0% | 0.34% | – |
| REPL | New | Replimune Group Incput | $5,357,141 | – | 313,100 | +100.0% | 0.34% | – |
| REPL | New | Replimune Group Inccall | $4,277,500 | – | 250,000 | +100.0% | 0.27% | – |
| NXTC | Nextcure Inc | $3,446,694 | -28.3% | 2,671,856 | 0.0% | 0.22% | -31.1% | |
| NCNA | Nucana PLCsponsored adr | $3,415,999 | -22.8% | 5,599,999 | 0.0% | 0.22% | -25.9% | |
| BOLT | Bolt Biotherapeutics Inc | $2,864,614 | -18.8% | 2,754,437 | 0.0% | 0.18% | -21.6% | |
| Buy | Marinus Pharmaceuticals Inccall | $2,580,830 | +18.8% | 320,600 | +60.3% | 0.16% | +14.8% | |
| AGEN | New | Agenus Inccall | $1,808,000 | – | 1,600,000 | +100.0% | 0.11% | – |
| Nucana PLC | $1,464,000 | -22.8% | 2,400,000 | 0.0% | 0.09% | -25.8% | ||
| IMTXW | New | Immatics NV*w exp 07/01/2025 | $1,128,892 | – | 318,896 | +100.0% | 0.07% | – |
| SYK | New | Stryker Corporation | $896,052 | – | 3,279 | +100.0% | 0.06% | – |
| PDSB | PDS Biotechnology Corp | $720,307 | +0.4% | 142,635 | 0.0% | 0.04% | -4.3% | |
| SVRA | Buy | Savara Inc | $596,892 | +94.1% | 157,908 | +64.1% | 0.04% | +90.0% |
| GRTX | Galera Therapeutics Inc | $539,958 | -94.4% | 3,083,712 | 0.0% | 0.03% | -94.6% | |
| IKNA | New | Ikena Oncology Inc | $501,033 | – | 115,712 | +100.0% | 0.03% | – |
| FUSN | Fusion Pharmaceuticals Inc | $304,457 | -44.3% | 117,099 | 0.0% | 0.02% | -47.2% | |
| MIRM | Mirum Pharmaceuticals Inc | $287,212 | +22.1% | 9,089 | 0.0% | 0.02% | +20.0% | |
| CBAY | New | CymaBay Therapeutics Incput | $164,606 | – | 11,040 | +100.0% | 0.01% | – |
| SPRB | Spruce Biosciences Inc | $131,146 | +5.1% | 58,029 | 0.0% | 0.01% | 0.0% | |
| New | Synlogic Inc | $107,710 | – | 38,331 | +100.0% | 0.01% | – | |
| SYBX | Exit | Synlogic Inc | $0 | – | -574,972 | -100.0% | -0.02% | – |
| ALLK | Exit | Allakos Inc | $0 | – | -62,465 | -100.0% | -0.02% | – |
| FGEN | Exit | FibroGen Inccall | $0 | – | -250,000 | -100.0% | -0.04% | – |
| FGEN | Exit | FibroGen Inc | $0 | – | -637,567 | -100.0% | -0.11% | – |
| FGEN | Exit | FibroGen Incput | $0 | – | -650,000 | -100.0% | -0.12% | – |
| VIR | Exit | Vir Biotechnology Incput | $0 | – | -300,000 | -100.0% | -0.48% | – |
| PTCT | Exit | PTC Therapeutics Inc | $0 | – | -260,443 | -100.0% | -0.69% | – |
| VIR | Exit | Vir Biotechnology Inc | $0 | – | -488,117 | -100.0% | -0.78% | – |
| RVMD | Exit | Revolution Medicines Inc | $0 | – | -520,377 | -100.0% | -0.91% | – |
| BAX | Exit | Baxter Intl Inc | $0 | – | -362,200 | -100.0% | -1.08% | – |
| RETA | Exit | Reata Pharmaceuticals Inccl a | $0 | – | -322,471 | -100.0% | -2.15% | – |
| BSX | Exit | Boston Scientific Corp | $0 | – | -608,861 | -100.0% | -2.16% | – |
| VRTX | Exit | Vertex Pharmaceuticals Inc | $0 | – | -145,300 | -100.0% | -3.35% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.