$1.32 Billion is the total value of Sofinnova Investments, Inc.'s 64 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 50.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KRTX | Karuna Therapeutics, Inc. | $247,631,000 | -3.2% | 1,953,077 | 0.0% | 18.79% | +25.8% | |
| NTRA | Natera Inc | $126,229,000 | -56.4% | 3,102,960 | 0.0% | 9.58% | -43.4% | |
| New | Cincor Pharma, Inc. | $97,767,000 | – | 5,573,949 | +100.0% | 7.42% | – | |
| VERA | Buy | Vera Therapeutics, Inc.cl a | $74,732,000 | -4.0% | 3,181,442 | +9.1% | 5.67% | +24.7% |
| AVTE | Aerovate Therapeutics, Inc. | $68,897,000 | +55.5% | 3,758,686 | 0.0% | 5.23% | +102.0% | |
| QQQ | Buy | Invesco QQQ Trust Series 1put | $63,445,000 | +59.5% | 175,000 | +75.0% | 4.82% | +107.2% |
| ASND | Ascendis Pharma A/Sadr | $58,659,000 | -12.8% | 499,824 | 0.0% | 4.45% | +13.3% | |
| AZN | New | AstraZeneca PLCadr | $36,746,000 | – | 553,903 | +100.0% | 2.79% | – |
| UTHR | Buy | United Therapeutics Corp | $35,735,000 | +27.5% | 199,183 | +53.5% | 2.71% | +65.6% |
| IWM | iShares Russell 2000 ETFput | $30,791,000 | -7.7% | 150,000 | 0.0% | 2.34% | +19.9% | |
| YMAB | Y-mAbs Therapeutics, Inc | $26,068,000 | -26.7% | 2,194,278 | 0.0% | 1.98% | -4.8% | |
| VRTX | New | Vertex Pharmaceuticals Inc | $24,793,000 | – | 95,003 | +100.0% | 1.88% | – |
| HZNP | Buy | Horizon Therapeutics PLC | $24,503,000 | +2.5% | 232,894 | +5.0% | 1.86% | +33.2% |
| DXCM | Buy | Dexcom Inc | $20,600,000 | +18.4% | 40,265 | +24.3% | 1.56% | +53.8% |
| RGNX | Sell | Regenxbio Inc | $20,381,000 | -38.2% | 614,085 | -39.1% | 1.55% | -19.6% |
| ZTS | New | Zoetis Inc | $20,099,000 | – | 106,574 | +100.0% | 1.52% | – |
| RETA | New | Reata Pharmaceuticals Inc | $19,739,000 | – | 602,545 | +100.0% | 1.50% | – |
| SRRA | Buy | Sierra Oncology Inc | $18,342,000 | +297.4% | 572,297 | +169.6% | 1.39% | +415.6% |
| XBI | New | Spdr S&P Biotech Etfput | $17,976,000 | – | 200,000 | +100.0% | 1.36% | – |
| ISEE | Buy | Iveric Bio Inc | $17,187,000 | +28.7% | 1,021,211 | +27.8% | 1.30% | +67.2% |
| TVTX | Sell | Travere Therapeutics Inc | $16,963,000 | -47.5% | 658,249 | -36.8% | 1.29% | -31.8% |
| GH | Buy | Guardant Health Inc | $15,897,000 | -31.7% | 239,995 | +3.2% | 1.21% | -11.2% |
| CCXI | Sell | ChemoCentryx Inc | $14,382,000 | -46.0% | 573,684 | -21.5% | 1.09% | -29.8% |
| BMRN | Buy | Biomarin Pharmaceutical Inc | $13,611,000 | +76.4% | 176,533 | +102.2% | 1.03% | +129.0% |
| NXTC | Nextcure, Inc | $12,985,000 | -19.0% | 2,671,856 | 0.0% | 0.99% | +5.3% | |
| PTGX | Buy | Protagonist Therapeutics Inc | $12,963,000 | -21.4% | 547,441 | +13.5% | 0.98% | +2.2% |
| SNDX | Sell | Syndax Pharmaceuticals Inc | $12,463,000 | -40.1% | 717,064 | -24.6% | 0.95% | -22.2% |
| CMPI | Checkmate Pharmaceuticals Inc | $11,505,000 | +11.1% | 3,606,707 | 0.0% | 0.87% | +44.3% | |
| INBX | Buy | Inhibrx Inc | $11,466,000 | -28.8% | 514,640 | +39.6% | 0.87% | -7.4% |
| IMTX | Buy | Immatics NV | $10,132,000 | -26.6% | 1,268,063 | +23.5% | 0.77% | -4.6% |
| JNCE | Sell | Jounce Therapeutics Inc | $10,057,000 | -23.9% | 1,481,219 | -6.4% | 0.76% | -1.2% |
| CTIC | New | CTI Biopharma Corp | $9,119,000 | – | 1,952,691 | +100.0% | 0.69% | – |
| ACET | Buy | Adicet Bio Inc | $8,313,000 | +52.8% | 416,289 | +33.9% | 0.63% | +98.4% |
| INZY | Inozyme Pharma, Inc. | $8,296,000 | -40.0% | 2,028,308 | 0.0% | 0.63% | -22.0% | |
| BOLT | Bolt Biotherapeutics, Inc. | $7,547,000 | -44.1% | 2,754,437 | 0.0% | 0.57% | -27.3% | |
| New | ChemoCentryx Inccall | $7,521,000 | – | 300,000 | +100.0% | 0.57% | – | |
| GRTX | Galera Therapeutics, Inc | $7,339,000 | -48.1% | 3,083,712 | 0.0% | 0.56% | -32.6% | |
| XNCR | Sell | Xencor Inc | $7,310,000 | -66.1% | 273,992 | -49.0% | 0.56% | -55.9% |
| AKUS | Akouos, Inc. | $7,197,000 | -44.1% | 1,515,074 | 0.0% | 0.55% | -27.4% | |
| BCYC | New | Bicycle Therapeutics PLCadr | $7,177,000 | – | 163,559 | +100.0% | 0.54% | – |
| OBSV | ObsEva SA | $7,172,000 | -24.1% | 4,749,623 | 0.0% | 0.54% | -1.4% | |
| SRPT | Sell | Sarepta Therapeutics Inc | $6,943,000 | -36.1% | 88,880 | -26.4% | 0.53% | -17.0% |
| IMGN | Sell | ImmunoGen Inc | $6,798,000 | -47.6% | 1,428,169 | -18.4% | 0.52% | -31.9% |
| NCNA | Nucana Plcadr | $5,594,000 | -58.0% | 5,599,999 | 0.0% | 0.42% | -45.4% | |
| FULC | Sell | Fulcrum Therapeutics Inc | $5,428,000 | -50.3% | 229,509 | -62.8% | 0.41% | -35.4% |
| PTGX | Sell | Protagonist Therapeutics Inccall | $4,736,000 | -53.9% | 200,000 | -33.5% | 0.36% | -40.3% |
| GERN | New | Geron Corp | $2,590,000 | – | 1,904,762 | +100.0% | 0.20% | – |
| PFE | New | Pfizer Inc | $2,556,000 | – | 49,378 | +100.0% | 0.19% | – |
| Nucana Plcordinary shares | $2,398,000 | -58.0% | 2,400,000 | 0.0% | 0.18% | -45.5% | ||
| CYTK | Sell | Cytokinetics Inc | $2,317,000 | -89.1% | 62,944 | -86.4% | 0.18% | -85.8% |
| ICPT | Sell | Intercept Pharmaceuticals Inccall | $1,627,000 | -33.6% | 100,000 | -33.5% | 0.12% | -14.0% |
| SYBX | Synlogic Inc. | $1,380,000 | -0.8% | 574,972 | 0.0% | 0.10% | +29.6% | |
| GERN | New | Geron Corpcall | $1,360,000 | – | 1,000,000 | +100.0% | 0.10% | – |
| New | Amylyx Pharmaceuticals Inc | $1,285,000 | – | 100,000 | +100.0% | 0.10% | – | |
| PDSB | PDS Biotechnology Corporation | $883,000 | -23.5% | 142,635 | 0.0% | 0.07% | 0.0% | |
| Sell | Mink Therapeutics Inc | $745,000 | -51.7% | 331,002 | -4.2% | 0.06% | -36.7% | |
| FUSN | Fusion Pharmaceuticals Inc | $607,000 | +86.2% | 78,066 | 0.0% | 0.05% | +142.1% | |
| PODD | Insulet Corp | $284,000 | 0.0% | 1,066 | 0.0% | 0.02% | +29.4% | |
| INSM | Sell | Insmed Inc | $126,000 | -99.0% | 5,368 | -98.8% | 0.01% | -98.6% |
| PTCT | Sell | PTC Therapeutics Inc | $130,000 | -97.5% | 3,480 | -97.4% | 0.01% | -96.8% |
| HRTX | Sell | Heron Therapeutics Inc | $63,000 | -99.8% | 11,060 | -99.6% | 0.01% | -99.7% |
| EW | Exit | Edwards Lifesciences Corp | $0 | – | -1,406 | -100.0% | -0.01% | – |
| ALGS | Exit | Aligos Therapeutics Inc | $0 | – | -127,791 | -100.0% | -0.09% | – |
| Exit | Marinus Pharmaceuticals Inc | $0 | – | -171,338 | -100.0% | -0.12% | – | |
| CYT | Exit | Cyteir Therapeutics Inc | $0 | – | -179,450 | -100.0% | -0.12% | – |
| KURA | Exit | Kura Oncology Inccall | $0 | – | -175,000 | -100.0% | -0.14% | – |
| ITCI | Exit | Intra-Cellular Therapies Inc | $0 | – | -56,915 | -100.0% | -0.17% | – |
| NVCR | Exit | Novocure Ltdcall | $0 | – | -50,000 | -100.0% | -0.22% | – |
| AXSM | Exit | Axsome Therapeutics Incput | $0 | – | -100,000 | -100.0% | -0.22% | – |
| KURA | Exit | Kura Oncology Inc | $0 | – | -369,173 | -100.0% | -0.30% | – |
| IFRX | Exit | Inflarx NV | $0 | – | -1,161,736 | -100.0% | -0.32% | – |
| AGEN | Exit | Agenus Inc | $0 | – | -1,961,032 | -100.0% | -0.37% | – |
| ZYME | Exit | Zymeworks Inc | $0 | – | -392,712 | -100.0% | -0.38% | – |
| VIR | Exit | Vir Biotechnology Incput | $0 | – | -200,000 | -100.0% | -0.49% | – |
| QURE | Exit | Uniqure NV | $0 | – | -495,025 | -100.0% | -0.60% | – |
| CLDX | Exit | Celldex Therapeutics Inc | $0 | – | -271,533 | -100.0% | -0.61% | – |
| IRTC | Exit | iRhythm Technologies Inc | $0 | – | -168,882 | -100.0% | -1.16% | – |
| BCRX | Exit | BioCryst Pharmaceuticals Inc | $0 | – | -1,510,473 | -100.0% | -1.22% | – |
| ALGN | Exit | Align Technology Inc | $0 | – | -38,159 | -100.0% | -1.46% | – |
| BPMC | Exit | Blueprint Medicines Corp | $0 | – | -245,182 | -100.0% | -1.53% | – |
| ABBV | Exit | Abbvie Inc | $0 | – | -312,018 | -100.0% | -2.47% | – |
| SPY | Exit | SPDR S&P 500 ETF Trustput | $0 | – | -100,000 | -100.0% | -2.77% | – |
| RHHBY | Exit | Roche Holding AGadr | $0 | – | -1,369,011 | -100.0% | -4.13% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-05-16
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.