$1.69 Billion is the total value of Sofinnova Investments, Inc.'s 70 reported holdings in Q3 2021. The portfolio turnover from Q2 2021 to Q3 2021 was 61.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NTRA | Buy | Natera Inc | $345,794,000 | -1.8% | 3,102,960 | +0.1% | 20.48% | +0.9% |
| KRTX | Buy | Karuna Therapeutics, Inc. | $238,920,000 | +7.4% | 1,953,077 | +0.0% | 14.15% | +10.3% |
| ASND | Sell | Ascendis Pharma A/Sadr | $79,667,000 | +16.0% | 499,824 | -4.2% | 4.72% | +19.2% |
| AVTE | Aerovate Therapeutics, Inc. | $78,857,000 | -8.1% | 3,758,686 | 0.0% | 4.67% | -5.6% | |
| AZN | Buy | AstraZeneca PLCadr | $67,764,000 | +17.9% | 1,128,272 | +17.6% | 4.01% | +21.1% |
| YMAB | Y-mAbs Therapeutics, Inc. | $62,625,000 | -15.6% | 2,194,278 | 0.0% | 3.71% | -13.2% | |
| VERA | Vera Therapeutics, Inc.cl a | $50,571,000 | +30.8% | 2,914,776 | 0.0% | 3.00% | +34.4% | |
| New | Merck & Co Inccall | $45,066,000 | – | 600,000 | +100.0% | 2.67% | – | |
| UTHR | Buy | United Therapeutics Corp | $40,994,000 | +5.7% | 222,094 | +2.8% | 2.43% | +8.7% |
| BOLT | Bolt Biotherapeutics, Inc. | $34,844,000 | -18.2% | 2,754,437 | 0.0% | 2.06% | -15.9% | |
| ALGN | Sell | Align Technology Inc | $31,275,000 | +8.7% | 47,000 | -0.2% | 1.85% | +11.7% |
| ABBV | New | Abbvie Inc | $29,405,000 | – | 272,600 | +100.0% | 1.74% | – |
| GRTX | Galera Therapeutics, Inc. | $24,978,000 | -17.6% | 3,083,712 | 0.0% | 1.48% | -15.3% | |
| HRTX | Buy | Heron Therapeutics Inc | $24,600,000 | +8.0% | 2,301,179 | +56.8% | 1.46% | +11.0% |
| New | Bristol-Myers Squibb Cocall | $23,668,000 | – | 400,000 | +100.0% | 1.40% | – | |
| INZY | Inozyme Pharma, Inc. | $23,508,000 | -32.0% | 2,028,308 | 0.0% | 1.39% | -30.1% | |
| DXCM | Buy | Dexcom Inc | $20,379,000 | +41.6% | 37,266 | +10.5% | 1.21% | +45.4% |
| BPMC | New | Blueprint Medicines Corp | $18,697,000 | – | 181,860 | +100.0% | 1.11% | – |
| New | Regeneron Pharmaceuticalsput | $18,155,000 | – | 30,000 | +100.0% | 1.08% | – | |
| NXTC | Nextcure, Inc | $18,008,000 | -16.1% | 2,671,856 | 0.0% | 1.07% | -13.8% | |
| AKUS | Akouos, Inc. | $17,590,000 | -7.5% | 1,515,074 | 0.0% | 1.04% | -4.9% | |
| New | United Therapeutics Corpput | $17,443,000 | – | 94,500 | +100.0% | 1.03% | – | |
| HZNP | New | Horizon Therapeutics Pub L | $17,251,000 | – | 157,487 | +100.0% | 1.02% | – |
| RETA | Buy | Reata Pharmaceuticals Inc | $15,845,000 | +40.6% | 157,488 | +97.8% | 0.94% | +44.5% |
| CYTK | Sell | Cytokinetics Inc | $15,248,000 | +60.1% | 426,632 | -11.4% | 0.90% | +64.5% |
| OBSV | ObsEva SA | $14,771,000 | +2.6% | 4,749,623 | 0.0% | 0.88% | +5.5% | |
| ZTS | New | Zoetis Inccl a | $14,755,000 | – | 76,000 | +100.0% | 0.87% | – |
| INSM | Sell | Insmed Inc | $14,737,000 | -38.7% | 535,120 | -36.6% | 0.87% | -37.0% |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $14,545,000 | -37.3% | 157,279 | -47.3% | 0.86% | -35.6% |
| NCNA | Nucana Plcadr | $14,448,000 | -6.9% | 5,599,999 | 0.0% | 0.86% | -4.3% | |
| CMPI | Checkmate Pharmaceuticals Inc | $14,319,000 | -33.4% | 3,606,707 | 0.0% | 0.85% | -31.6% | |
| KURA | Buy | Kura Oncology Inc | $14,143,000 | +52.6% | 755,121 | +69.9% | 0.84% | +56.9% |
| AGEN | Sell | Agenus Inc | $12,308,000 | -19.1% | 2,344,410 | -15.4% | 0.73% | -16.8% |
| ZYME | New | Zymeworks Inc | $11,924,000 | – | 410,619 | +100.0% | 0.71% | – |
| TVTX | New | Travere Therapeutics Inc | $10,604,000 | – | 437,280 | +100.0% | 0.63% | – |
| EXEL | Sell | Exelixis Inc | $10,325,000 | -47.5% | 488,414 | -54.8% | 0.61% | -46.1% |
| MRTX | Sell | Mirati Therapeutics Inc | $10,066,000 | -20.7% | 56,900 | -27.6% | 0.60% | -18.5% |
| BIIB | Sell | Biogen Inc | $9,401,000 | -75.5% | 33,220 | -70.0% | 0.56% | -74.8% |
| KDMN | New | Kadmon Holdings Inc | $9,113,000 | – | 1,046,312 | +100.0% | 0.54% | – |
| CCXI | Buy | ChemoCentryx Inc | $8,853,000 | +42.0% | 517,708 | +11.2% | 0.52% | +46.0% |
| New | ChemoCentryx Incput | $8,649,000 | – | 505,800 | +100.0% | 0.51% | – | |
| PTCT | Sell | PTC Therapeutics Inc | $8,559,000 | -65.2% | 230,019 | -60.5% | 0.51% | -64.2% |
| ITCI | Sell | Intra-Cellular Therapies Inc | $8,478,000 | -33.7% | 227,419 | -27.4% | 0.50% | -31.9% |
| ALXO | New | ALX Oncology Holdings Inc | $7,919,000 | – | 107,220 | +100.0% | 0.47% | – |
| SNDX | New | Syndax Pharmaceuticals Inc | $7,909,000 | – | 413,841 | +100.0% | 0.47% | – |
| CLDX | Buy | Celldex Therapeutics, Inc. | $7,398,000 | +64.2% | 137,032 | +1.7% | 0.44% | +68.5% |
| XLRN | Sell | Acceleron Pharma Inc | $6,813,000 | -76.8% | 39,589 | -83.1% | 0.40% | -76.2% |
| IMTX | Buy | Immatics N.V | $6,217,000 | +20.8% | 478,216 | +7.9% | 0.37% | +23.9% |
| Nucana Plcordinary shares | $6,192,000 | -6.9% | 2,400,000 | 0.0% | 0.37% | -4.2% | ||
| CTIC | Buy | CTI BioPharma Corp | $6,120,000 | +1326.6% | 2,074,714 | +1108.9% | 0.36% | +1348.0% |
| ISEE | New | Iveric Bio Inc | $5,804,000 | – | 357,400 | +100.0% | 0.34% | – |
| AMRN | Sell | Amarin Corpadr | $5,457,000 | +6.4% | 1,069,968 | -8.6% | 0.32% | +9.5% |
| RGNX | Sell | Regenxbio Inc | $5,349,000 | -67.8% | 127,593 | -70.2% | 0.32% | -66.9% |
| New | Protagonist Therapeutics Inccall | $5,316,000 | – | 300,000 | +100.0% | 0.32% | – | |
| PTGX | Sell | Protagonist Therapeutics Inc | $5,275,000 | -73.8% | 297,709 | -33.7% | 0.31% | -73.1% |
| GH | New | Guardant Health Inc | $5,000,000 | – | 40,000 | +100.0% | 0.30% | – |
| JNCE | Buy | Jounce Therapeutics Inc | $4,735,000 | +11.5% | 637,347 | +2.0% | 0.28% | +14.3% |
| SRRA | Buy | Sierra Oncology, Inc. | $4,528,000 | +9140.8% | 206,564 | +8162.6% | 0.27% | +8833.3% |
| CYT | Sell | Cyteir Therapeutics, Inc. | $4,323,000 | -23.8% | 246,321 | -7.0% | 0.26% | -21.7% |
| New | Iveric Bio Incput | $4,146,000 | – | 255,300 | +100.0% | 0.25% | – | |
| New | Novocure Ltdcall | $3,485,000 | – | 30,000 | +100.0% | 0.21% | – | |
| New | Intercept Pharmaceuticals Incall | $2,822,000 | – | 190,000 | +100.0% | 0.17% | – | |
| QURE | Sell | Uniqure NV | $2,521,000 | -74.8% | 78,742 | -75.7% | 0.15% | -74.1% |
| PDSB | PDS Biotechnology Corporation | $2,125,000 | +18.7% | 142,635 | 0.0% | 0.13% | +22.3% | |
| ALGS | Sell | Aligos Therapeutics Inc | $1,929,000 | -42.3% | 124,342 | -24.2% | 0.11% | -40.9% |
| Sell | Marinus Pharmaceuticals Inc | $1,897,000 | -69.5% | 166,711 | -51.8% | 0.11% | -68.7% | |
| SYBX | Synlogic Inc. | $1,754,000 | -21.6% | 574,972 | 0.0% | 0.10% | -19.4% | |
| FULC | New | Fulcrum Therapeutics Inc | $1,439,000 | – | 51,006 | +100.0% | 0.08% | – |
| FUSN | New | Fusion Pharmaceuticals Inc | $618,000 | – | 78,066 | +100.0% | 0.04% | – |
| PODD | Sell | Insulet Corp | $303,000 | -98.4% | 1,066 | -98.4% | 0.02% | -98.3% |
| SVRA | Exit | Savara Inc | $0 | – | -1,278,424 | -100.0% | -0.12% | – |
| Exit | TCR2 Therapeutics Incput | $0 | – | -139,700 | -100.0% | -0.13% | – | |
| Exit | ACADIA Pharmaceuticals Inccall | $0 | – | -100,000 | -100.0% | -0.14% | – | |
| BCRX | Exit | BioCryst Pharmaceuticals Inc | $0 | – | -158,609 | -100.0% | -0.14% | – |
| REPL | Exit | Replimune Group Inc | $0 | – | -71,661 | -100.0% | -0.16% | – |
| OTIC | Exit | Otonomy Inc | $0 | – | -1,251,256 | -100.0% | -0.16% | – |
| Exit | ChemoCentryx Inccall | $0 | – | -215,000 | -100.0% | -0.17% | – | |
| FATE | Exit | Fate Therapeutics Inc | $0 | – | -46,386 | -100.0% | -0.23% | – |
| MIRM | Exit | Mirum Pharmaceuticals Inc | $0 | – | -259,465 | -100.0% | -0.26% | – |
| TCRR | Exit | TCR2 Therapeutics Inc | $0 | – | -296,282 | -100.0% | -0.28% | – |
| Exit | FibroGen, Inc.put | $0 | – | -200,000 | -100.0% | -0.31% | – | |
| CHRS | Exit | Coherus BioSciences | $0 | – | -434,555 | -100.0% | -0.35% | – |
| MGNX | Exit | MacroGenics Inc | $0 | – | -234,504 | -100.0% | -0.36% | – |
| AMGN | Exit | Amgen Inc | $0 | – | -40,500 | -100.0% | -0.57% | – |
| AGIO | Exit | Agios Pharmaceuticals, Inc. | $0 | – | -219,033 | -100.0% | -0.70% | – |
| VRTX | Exit | Vertex Pharmaceuticals Inc | $0 | – | -88,214 | -100.0% | -1.02% | – |
| NBIX | Exit | Neurocrine Biosciences, Inc. | $0 | – | -203,200 | -100.0% | -1.14% | – |
| Exit | ARK ETF TRput | $0 | – | -250,000 | -100.0% | -1.33% | – | |
| Exit | iShares TRput | $0 | – | -325,000 | -100.0% | -3.06% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-11-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.