$1.35 Billion is the total value of Sofinnova Investments, Inc.'s 157 reported holdings in Q3 2020. The portfolio turnover from Q2 2020 to Q3 2020 was 57.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NTRA | Natera | $223,984,000 | +44.9% | 3,100,560 | 0.0% | 16.61% | +70.4% | |
| ASND | Ascendis Pharma A/Sadr | $171,276,000 | +4.3% | 1,109,874 | 0.0% | 12.70% | +22.7% | |
| KRTX | Buy | Karuna Therapeutics, Inc. | $150,963,000 | -28.2% | 1,952,441 | +3.5% | 11.19% | -15.5% |
| YMAB | Y-mAbs Therapeutics, Inc | $84,238,000 | -11.1% | 2,194,278 | 0.0% | 6.25% | +4.5% | |
| INZY | New | Inozyme Pharma, Inc. | $53,324,000 | – | 2,028,308 | +100.0% | 3.95% | – |
| CMPI | New | Checkmate Pharmaceuticals Inc | $41,513,000 | – | 3,606,707 | +100.0% | 3.08% | – |
| New | Amgen Inccall | $41,248,000 | – | 59,500 | +100.0% | 3.06% | – | |
| AKUS | Akouos, Incadr | $34,650,000 | +1.6% | 1,515,073 | 0.0% | 2.57% | +19.5% | |
| UTHR | Buy | United Therapeutics Corp | $32,417,000 | -12.0% | 320,959 | +5.4% | 2.40% | +3.5% |
| ABBV | Buy | Abbvie Inc | $29,898,000 | +20.9% | 341,340 | +35.5% | 2.22% | +42.1% |
| NCNA | Buy | Nucana Biomed Ltdadr | $28,952,000 | +136.1% | 5,599,999 | +147.1% | 2.15% | +177.7% |
| AMGN | New | Amgen Inc | $28,369,000 | – | 111,619 | +100.0% | 2.10% | – |
| GRTX | Galera Therapeutics, Inc | $27,877,000 | +26.6% | 3,083,712 | 0.0% | 2.07% | +48.9% | |
| NXTC | Nextcure, Inc | $23,512,000 | -59.0% | 2,671,856 | 0.0% | 1.74% | -51.7% | |
| LLY | Sell | Lilly Eli & Co | $21,083,000 | -13.8% | 142,432 | -4.3% | 1.56% | +1.4% |
| INSM | Buy | Insmed Inc | $19,771,000 | +48.3% | 615,143 | +27.1% | 1.47% | +74.5% |
| BMRN | Buy | Biomarin Pharmaceutical Inc | $19,678,000 | +153.7% | 258,653 | +311.2% | 1.46% | +198.4% |
| PTCT | Sell | PTC Therapeutics Inc | $18,941,000 | -14.8% | 405,152 | -7.6% | 1.40% | +0.2% |
| JAZZ | Sell | Jazz Pharmaceuticals PLC | $18,575,000 | -30.8% | 130,268 | -46.5% | 1.38% | -18.7% |
| MRK | Sell | Merck & Co Inc | $15,807,000 | -54.7% | 190,559 | -57.8% | 1.17% | -46.7% |
| MRUS | Merus N.V. | $15,732,000 | -25.4% | 1,311,039 | 0.0% | 1.17% | -12.3% | |
| ITCI | Buy | Intra-Cellular Therapies Inc | $12,921,000 | +108.1% | 503,555 | +108.2% | 0.96% | +145.0% |
| Nucana Biomed Ltdordinary shares | $12,408,000 | -4.4% | 2,400,000 | 0.0% | 0.92% | +12.3% | ||
| OBSV | ObsEva SA | $11,779,000 | -57.9% | 4,749,623 | 0.0% | 0.87% | -50.5% | |
| ATHA | New | Athira Pharma, Inc. | $9,399,000 | – | 509,168 | +100.0% | 0.70% | – |
| New | Marinus Pharmaceuticals Inccall | $8,995,000 | – | 175,000 | +100.0% | 0.67% | – | |
| OTIC | Buy | Otonomy Inc | $8,551,000 | +43.0% | 2,111,596 | +27.9% | 0.63% | +68.2% |
| GWPH | New | GW Pharmaceuticals PLCadr | $8,075,000 | – | 82,944 | +100.0% | 0.60% | – |
| CHRS | Sell | Coherus BioSciences | $7,970,000 | -76.9% | 434,555 | -77.5% | 0.59% | -72.9% |
| CYTK | Buy | Cytokinetics Inc | $7,562,000 | +100.3% | 349,296 | +118.0% | 0.56% | +135.7% |
| ZYME | Sell | Zymeworks Inc | $7,075,000 | -34.6% | 151,902 | -49.3% | 0.52% | -23.0% |
| New | Cytokinetics Incput | $7,036,000 | – | 325,000 | +100.0% | 0.52% | – | |
| PTGX | Buy | Protagonist Therapeutics Inc | $6,994,000 | +21.5% | 357,769 | +9.7% | 0.52% | +43.0% |
| KURA | Sell | Kura Oncology Inc | $6,902,000 | -30.7% | 225,259 | -63.1% | 0.51% | -18.5% |
| SUPN | Sell | Supernus Pharmaceuticals Inc | $6,883,000 | -39.4% | 330,295 | -30.9% | 0.51% | -28.8% |
| XLRN | Sell | Acceleron Pharma Inc | $6,700,000 | -67.6% | 59,546 | -72.6% | 0.50% | -61.9% |
| TGTX | Sell | TG Therapeutics Inc | $6,700,000 | -50.6% | 250,401 | -64.0% | 0.50% | -41.9% |
| RETA | Buy | Reata Pharmaceuticals Inc | $6,685,000 | +228.7% | 68,615 | +426.4% | 0.50% | +287.5% |
| MYOK | Sell | MyoKardia Inc | $6,680,000 | -38.2% | 48,998 | -56.2% | 0.50% | -27.3% |
| ARNA | Buy | Arena Pharmaceuticals Inc | $6,592,000 | +651.7% | 88,150 | +532.9% | 0.49% | +789.1% |
| OVID | New | Ovid Therapeutics Inc | $6,300,000 | – | 1,097,621 | +100.0% | 0.47% | – |
| MIRM | Sell | Mirum Pharmaceuticals Inc | $6,191,000 | -41.3% | 321,252 | -40.7% | 0.46% | -31.0% |
| New | Reata Pharmaceuticals Incput | $5,845,000 | – | 60,000 | +100.0% | 0.43% | – | |
| Novocure Ltdcall | $5,566,000 | +87.7% | 50,000 | 0.0% | 0.41% | +120.9% | ||
| AMRN | Sell | Amarin Corpadr | $4,928,000 | -86.3% | 1,170,584 | -77.5% | 0.36% | -83.9% |
| ACRS | Aclaris Therapeutics | $4,913,000 | +58.6% | 1,911,573 | 0.0% | 0.36% | +86.7% | |
| PBYI | Sell | Puma Biotechnology Inc | $4,803,000 | -61.5% | 475,982 | -60.3% | 0.36% | -54.8% |
| CHMA | Sell | Chiasma | $4,504,000 | -48.6% | 1,047,354 | -35.8% | 0.33% | -39.6% |
| CCXI | Sell | ChemoCentryx Inc | $4,451,000 | -20.2% | 81,235 | -16.2% | 0.33% | -6.2% |
| KNSA | Sell | Kiniksa Pharmaceuticals, Ltd | $4,238,000 | -79.5% | 276,628 | -65.8% | 0.31% | -75.9% |
| AGTC | Sell | Applied Genetic Technologies Corp | $4,010,000 | -36.8% | 825,071 | -28.0% | 0.30% | -25.8% |
| New | Moderna Inccall | $3,537,000 | – | 50,000 | +100.0% | 0.26% | – | |
| TCRR | New | TCR2 Therapeutics Inc | $3,516,000 | – | 173,028 | +100.0% | 0.26% | – |
| IMTX | New | Immatics NV | $3,453,000 | – | 325,527 | +100.0% | 0.26% | – |
| LQDA | Sell | Liquidia Technologies Inc | $3,342,000 | -50.4% | 679,400 | -15.1% | 0.25% | -41.6% |
| BCRX | Sell | BioCryst Pharmaceuticals Inc | $2,725,000 | -57.9% | 793,054 | -41.6% | 0.20% | -50.5% |
| FIXX | Sell | Homology Medicines Inc | $2,547,000 | -51.3% | 238,015 | -30.9% | 0.19% | -42.7% |
| KDMN | Sell | Kadmon Holdings Inc | $2,468,000 | -68.5% | 629,923 | -58.9% | 0.18% | -63.0% |
| CGEN | Buy | Compugen Ltd | $2,383,000 | +53.1% | 146,592 | +41.5% | 0.18% | +80.6% |
| ETTX | Sell | Entasis Therapeutics Holdings Inc. | $2,065,000 | -40.9% | 1,012,408 | -14.2% | 0.15% | -30.5% |
| ACAD | New | ACADIA Pharmaceuticals Inc | $2,022,000 | – | 48,996 | +100.0% | 0.15% | – |
| CALA | Sell | Calithera Biosciences Inc | $1,701,000 | -69.0% | 493,297 | -52.6% | 0.13% | -63.6% |
| FATE | New | Fate Therapeutics Inc | $1,654,000 | – | 41,400 | +100.0% | 0.12% | – |
| RGNX | New | Regenxbio Inc | $1,638,000 | – | 59,507 | +100.0% | 0.12% | – |
| SYBX | Synlogic Inc. | $1,161,000 | -0.5% | 574,972 | 0.0% | 0.09% | +16.2% | |
| SVRA | New | Savara Inc | $409,000 | – | 375,591 | +100.0% | 0.03% | – |
| PDSB | PDS Biotechnology Corporation | $332,000 | +15.7% | 142,635 | 0.0% | 0.02% | +38.9% | |
| New | Kadmon Holdings Incwarrant | $137,000 | – | 240,091 | +100.0% | 0.01% | – | |
| ORIC | Exit | Oric Pharmaceuticals Inc | $0 | – | -17,369 | -100.0% | -0.04% | – |
| RIGL | Exit | Rigel Pharmaceuticals Inc | $0 | – | -339,695 | -100.0% | -0.04% | – |
| MRTX | Exit | Mirati Therapeutics Inc | $0 | – | -8,072 | -100.0% | -0.06% | – |
| IMVT | Exit | Immunovant Inc | $0 | – | -40,513 | -100.0% | -0.06% | – |
| NTLA | Exit | Intellia Therapeutics Inc | $0 | – | -57,500 | -100.0% | -0.08% | – |
| MNLO | Exit | Menlo Therapeutics Inc | $0 | – | -725,571 | -100.0% | -0.08% | – |
| SNDX | Exit | Syndax Pharmaceuticals Inc | $0 | – | -91,964 | -100.0% | -0.09% | – |
| APLS | Exit | Apellis Pharmaceuticals, Inc | $0 | – | -49,580 | -100.0% | -0.10% | – |
| Exit | PTC Therapeutics Inccall | $0 | – | -60,000 | -100.0% | -0.19% | – | |
| MRSN | Exit | Mersana Therapeutics Inc | $0 | – | -137,966 | -100.0% | -0.20% | – |
| KALA | Exit | Kala Pharmaceuticals Inc | $0 | – | -506,647 | -100.0% | -0.34% | – |
| Exit | Intra-Cellular Therapies Incput | $0 | – | -220,000 | -100.0% | -0.36% | – | |
| Exit | Pfizer Inccall | $0 | – | -175,000 | -100.0% | -0.36% | – | |
| CNST | Exit | Constellation Pharmaceuticals Inc | $0 | – | -207,087 | -100.0% | -0.39% | – |
| AXSM | Exit | Axsome Therapeutics Inc | $0 | – | -86,978 | -100.0% | -0.45% | – |
| BPMC | Exit | Blueprint Medicines Corp | $0 | – | -94,891 | -100.0% | -0.47% | – |
| Exit | Invesco QQQ Trustput | $0 | – | -30,000 | -100.0% | -0.47% | – | |
| AKBA | Exit | Akebia Therapeutics Inc | $0 | – | -681,892 | -100.0% | -0.58% | – |
| Exit | iShares Trput | $0 | – | -70,000 | -100.0% | -0.63% | – | |
| HZNP | Exit | Horizon Therapeutics PLC | $0 | – | -252,958 | -100.0% | -0.89% | – |
| Exit | SPDR Ser Trput | $0 | – | -150,000 | -100.0% | -0.95% | – | |
| Exit | SPDR Ser Trput | $0 | – | -150,000 | -100.0% | -1.06% | – | |
| Exit | Alnylam Pharmaceuticals Inccall | $0 | – | -150,000 | -100.0% | -1.40% | – | |
| GILD | Exit | Gilead Sciences Inc | $0 | – | -403,494 | -100.0% | -1.96% | – |
| Exit | Amgen Incput | $0 | – | -168,500 | -100.0% | -2.50% | – | |
| PRNB | Exit | Principia Biopharma | $0 | – | -1,417,258 | -100.0% | -5.34% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2020-11-13
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.