$1.11 Billion is the total value of Sofinnova Investments, Inc.'s 167 reported holdings in Q3 2019. The portfolio turnover from Q2 2019 to Q3 2019 was 59.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ASND | Buy | Ascendis Pharma A/Sadr | $106,903,000 | -15.6% | 1,109,874 | +0.9% | 9.67% | -16.9% |
| NTRA | Natera | $101,698,000 | +18.9% | 3,100,560 | 0.0% | 9.20% | +17.0% | |
| AMRN | Amarinadr | $78,958,000 | -21.8% | 5,208,305 | 0.0% | 7.14% | -23.1% | |
| NXTC | Nextcure, Inc | $77,799,000 | +105.9% | 2,521,856 | 0.0% | 7.03% | +102.7% | |
| YMAB | Y-mAbs Therapeutics, Inc | $54,837,000 | +13.9% | 2,104,278 | 0.0% | 4.96% | +12.1% | |
| ONCE | Spark Therapeutics | $46,674,000 | -5.3% | 481,270 | 0.0% | 4.22% | -6.8% | |
| PRNB | Sell | Principia Biopharma | $40,023,000 | -40.8% | 1,417,258 | -30.5% | 3.62% | -41.8% |
| OBSV | ObsEva SA | $39,564,000 | -26.3% | 4,749,623 | 0.0% | 3.58% | -27.5% | |
| CHRS | Sell | Coherus BioSciences | $39,167,000 | -15.3% | 1,933,221 | -7.6% | 3.54% | -16.7% |
| MRUS | Merus N.V. | $34,946,000 | +21.6% | 1,961,039 | 0.0% | 3.16% | +19.7% | |
| KRTX | Karuna Therapeutics, Inc. | $28,223,000 | -18.5% | 1,729,352 | 0.0% | 2.55% | -19.8% | |
| New | Health Care Select Sector SPDRput | $27,039,000 | – | 300,000 | +100.0% | 2.44% | – | |
| BOLD | Audentes Therapeutics | $26,226,000 | -25.8% | 933,640 | 0.0% | 2.37% | -27.0% | |
| BMY | Buy | Bristol-Myers Squibb Co | $24,257,000 | +207.7% | 478,349 | +175.2% | 2.19% | +202.9% |
| AGN | Buy | Allergan plc | $22,624,000 | +60.0% | 134,433 | +59.2% | 2.05% | +57.5% |
| VRTX | Buy | Vertex Pharmaceuticals Inc | $20,616,000 | +123.5% | 121,690 | +141.9% | 1.86% | +119.8% |
| AMGN | New | Amgen Inc | $17,861,000 | – | 92,300 | +100.0% | 1.62% | – |
| Nucana Biomed Ltdordinary shares | $17,376,000 | -30.3% | 2,400,000 | 0.0% | 1.57% | -31.4% | ||
| NBIX | Buy | Neurocrine Biosciences Inc | $17,273,000 | +31.3% | 191,679 | +23.0% | 1.56% | +29.2% |
| NCNA | Nucana Biomed Ltdadr | $16,411,000 | -30.2% | 2,266,666 | 0.0% | 1.48% | -31.4% | |
| XLRN | Buy | Acceleron Pharma Inc | $16,130,000 | +62.9% | 408,262 | +69.4% | 1.46% | +60.2% |
| UTHR | New | United Therapeutics Corp | $15,473,000 | – | 194,014 | +100.0% | 1.40% | – |
| PFE | New | Pfizer Inc | $14,753,000 | – | 410,607 | +100.0% | 1.33% | – |
| New | Reata Pharmaceuticals Incput | $11,931,000 | – | 148,600 | +100.0% | 1.08% | – | |
| RETA | Buy | Reata Pharmaceuticals Inc | $11,936,000 | +9.5% | 148,669 | +28.7% | 1.08% | +7.7% |
| ITRM | Iterum Therapeutics | $9,962,000 | -16.1% | 1,726,514 | 0.0% | 0.90% | -17.4% | |
| HALO | Sell | Halozyme Therapeutics Inc | $9,867,000 | -16.8% | 636,167 | -7.8% | 0.89% | -18.2% |
| TGTX | Buy | TG Therapeutics Inc | $9,734,000 | -10.8% | 1,733,628 | +37.4% | 0.88% | -12.3% |
| PTCT | Sell | PTC Therapeutics Inc | $9,715,000 | -41.5% | 287,245 | -22.1% | 0.88% | -42.4% |
| CHMA | Chiasma | $8,070,000 | -33.7% | 1,630,221 | 0.0% | 0.73% | -34.8% | |
| SRPT | New | Sarepta Therapeutics Inc | $8,016,000 | – | 106,414 | +100.0% | 0.72% | – |
| KNSA | Kiniksa Pharmaceuticals, Ltd | $7,852,000 | -37.1% | 922,700 | 0.0% | 0.71% | -38.2% | |
| MGNX | Buy | MacroGenics Inc | $7,421,000 | -20.6% | 581,554 | +5.7% | 0.67% | -21.8% |
| AIMT | New | Aimmune Therapeutics Inc | $7,261,000 | – | 346,770 | +100.0% | 0.66% | – |
| ETTX | Entasis Therapeutics Holdings Inc. | $7,034,000 | -7.6% | 1,180,178 | 0.0% | 0.64% | -9.0% | |
| KDMN | Buy | Kadmon Holdings Inc | $6,577,000 | +44.9% | 2,609,758 | +18.4% | 0.60% | +42.7% |
| DERM | Buy | Dermira Inc | $6,327,000 | +0.3% | 990,168 | +50.1% | 0.57% | -1.4% |
| New | Beigene Ltdcall | $6,123,000 | – | 50,000 | +100.0% | 0.55% | – | |
| MYOK | New | MyoKardia Inc | $5,942,000 | – | 113,926 | +100.0% | 0.54% | – |
| FATE | New | Fate Therapeutics Inc | $5,926,000 | – | 381,600 | +100.0% | 0.54% | – |
| FOLD | Buy | Amicus Therapeutics Inc | $5,798,000 | -20.3% | 722,974 | +23.9% | 0.52% | -21.7% |
| BMRN | Biomarin Pharmaceutical Inc | $5,722,000 | -21.3% | 84,896 | 0.0% | 0.52% | -22.6% | |
| DRNA | New | Dicerna Pharmaceuticals Inc | $4,923,000 | – | 342,755 | +100.0% | 0.44% | – |
| AKBA | Buy | Akebia Therapeutics Inc | $4,811,000 | +17.2% | 1,227,191 | +44.7% | 0.44% | +15.4% |
| ZYME | Buy | Zymeworks Inc | $4,672,000 | +12.9% | 188,438 | +0.2% | 0.42% | +11.1% |
| XBIT | Buy | XBiotech Inc | $3,751,000 | +49.1% | 358,663 | +8.1% | 0.34% | +46.8% |
| FOMX | Buy | Foamix Pharmaceuticals Ltd | $3,645,000 | +37.3% | 1,199,254 | +7.5% | 0.33% | +35.2% |
| OTIC | Buy | Otonomy Inc | $3,436,000 | -6.6% | 1,437,965 | +7.5% | 0.31% | -8.0% |
| ORTX | Sell | Orchard Therapeutics PLCadr | $3,367,000 | -34.1% | 283,406 | -22.5% | 0.30% | -35.3% |
| FTSV | Buy | Forty Seven Inc | $3,335,000 | +164.9% | 519,298 | +337.1% | 0.30% | +160.3% |
| CALA | Buy | Calithera Biosciences Inc | $2,982,000 | +44.3% | 964,852 | +82.1% | 0.27% | +42.1% |
| ARQL | Buy | ArQule Inc | $2,820,000 | -9.1% | 393,387 | +39.6% | 0.26% | -10.5% |
| FIXX | New | Homology Medicines Inc | $2,647,000 | – | 146,297 | +100.0% | 0.24% | – |
| CYTK | New | Cytokinetics Inc | $2,401,000 | – | 210,992 | +100.0% | 0.22% | – |
| MRTX | New | Mirati Therapeutics Inc | $2,399,000 | – | 30,800 | +100.0% | 0.22% | – |
| HRTX | New | Heron Therapeutics Inccall | $2,283,000 | – | 123,400 | +100.0% | 0.21% | – |
| ACRS | Aclaris Therapeutics | $2,064,000 | -50.7% | 1,911,573 | 0.0% | 0.19% | -51.4% | |
| HRTX | Sell | Heron Therapeutics Inc | $1,917,000 | -83.3% | 103,602 | -83.2% | 0.17% | -83.6% |
| ALGN | New | Align Technology Inc | $1,810,000 | – | 10,000 | +100.0% | 0.16% | – |
| SNDX | Buy | Syndax Pharmaceuticals Inc | $1,817,000 | -19.6% | 243,150 | +0.2% | 0.16% | -21.2% |
| KALA | Buy | Kala Pharmaceuticals Inc | $1,819,000 | -4.1% | 478,206 | +60.9% | 0.16% | -5.7% |
| PTLA | New | Portola Pharmaceuticals Inc | $1,588,000 | – | 59,191 | +100.0% | 0.14% | – |
| APLT | Applied Therapeutics Inc | $1,560,000 | +33.3% | 142,004 | 0.0% | 0.14% | +30.6% | |
| New | Syndax Pharmaceuticals Incput | $1,494,000 | – | 200,000 | +100.0% | 0.14% | – | |
| BCRX | Buy | BioCryst Pharmaceuticals Inc | $1,481,000 | -8.4% | 516,734 | +21.2% | 0.13% | -9.5% |
| SVRA | New | Savara Inc | $1,397,000 | – | 527,318 | +100.0% | 0.13% | – |
| SYBX | Synlogic Inc. | $1,317,000 | -74.8% | 574,972 | 0.0% | 0.12% | -75.3% | |
| APLS | Apellis Pharmaceuticals, Inc | $1,194,000 | -4.9% | 49,580 | 0.0% | 0.11% | -6.1% | |
| New | Heron Therapeutics Inccall | $995,000 | – | 53,800 | +100.0% | 0.09% | – | |
| SNSS | New | Sunesis Pharmaceuticals Inc | $816,000 | – | 1,133,947 | +100.0% | 0.07% | – |
| New | Syndax Pharmaceuticals Inccall | $746,000 | – | 100,000 | +100.0% | 0.07% | – | |
| PDSB | PDS Biotechnology Corporation | $482,000 | -43.6% | 142,635 | 0.0% | 0.04% | -43.6% | |
| AUTL | Exit | Autolus Therapeutics PLCadr | $0 | – | -65,780 | -100.0% | -0.10% | – |
| ACOR | Exit | Acorda Therapeutics Inc | $0 | – | -194,036 | -100.0% | -0.14% | – |
| ITCI | Exit | Intra-Cellular Therapies Inc | $0 | – | -125,955 | -100.0% | -0.15% | – |
| CLVS | Exit | Clovis Oncology Inc | $0 | – | -125,303 | -100.0% | -0.17% | – |
| OSMT | Exit | Osmotica Pharmaceuticals PLC | $0 | – | -525,198 | -100.0% | -0.18% | – |
| ALNY | Exit | Alnylam Pharmaceuticals Inc | $0 | – | -27,792 | -100.0% | -0.18% | – |
| ABBV | Exit | AbbVie Inc | $0 | – | -28,911 | -100.0% | -0.19% | – |
| ADVM | Exit | Adverum Biotechnologies Inc | $0 | – | -187,059 | -100.0% | -0.20% | – |
| Exit | Deciphera Pharmaceuticals Incput | $0 | – | -100,100 | -100.0% | -0.21% | – | |
| Exit | Intra-Cellular Therapies Inccall | $0 | – | -175,000 | -100.0% | -0.21% | – | |
| Exit | Zogenix Inccall | $0 | – | -50,000 | -100.0% | -0.22% | – | |
| QURE | Exit | Uniqure NVcall | $0 | – | -50,000 | -100.0% | -0.36% | – |
| ACAD | Exit | ACADIA Pharmaceuticals Inc | $0 | – | -155,576 | -100.0% | -0.38% | – |
| Exit | Bristol-Myers Squibb Cocall | $0 | – | -100,000 | -100.0% | -0.42% | – | |
| INCY | Exit | Incyte Corp | $0 | – | -69,612 | -100.0% | -0.54% | – |
| Exit | Allergan plccall | $0 | – | -50,000 | -100.0% | -0.77% | – | |
| Exit | Amgen Incput | $0 | – | -50,000 | -100.0% | -0.85% | – | |
| Exit | MorphoSys AG | $0 | – | -96,135 | -100.0% | -0.85% | – | |
| NVO | Exit | Novo Nordisk A/Sadr | $0 | – | -323,697 | -100.0% | -1.52% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Natera, Inc. | 23 | Q3 2023 | 20.5% |
| Ascendis Pharma A/S | 23 | Q3 2023 | 27.9% |
| NuCana plc | 23 | Q3 2023 | 15.2% |
| Synlogic Inc. (fmrly Mirna) | 22 | Q2 2023 | 0.9% |
| Y-mAbs Therapeutics, Inc. | 21 | Q3 2023 | 6.5% |
| ObsEva SA | 20 | Q4 2022 | 11.0% |
| Nucana PLC | 19 | Q3 2023 | 9.7% |
| SYNDAX PHARMACEUTICALS INC | 19 | Q3 2023 | 2.2% |
| PDS Biotechnology Corporation | 19 | Q3 2023 | 0.1% |
| Karuna Therapeutics, Inc. | 18 | Q3 2023 | 27.1% |
View Sofinnova Investments, Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| OTONOMY, INC.Sold out | February 14, 2022 | 0 | 0.0% |
View Sofinnova Investments, Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-11 |
| 13F-HR | 2023-02-14 |
| 13F-HR | 2022-11-08 |
| 13F-HR | 2022-08-15 |
| 13F-HR | 2022-05-16 |
| 13F-HR | 2022-02-14 |
| SC 13G/A | 2022-02-14 |
View Sofinnova Investments, Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.