$277 Million is the total value of Opaleye Management Inc.'s 49 reported holdings in Q3 2019. The portfolio turnover from Q2 2019 to Q3 2019 was 65.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CDXS | CODEXIS INC | $18,515,000 | -25.6% | 1,350,000 | 0.0% | 6.70% | -11.7% | |
| STXS | New | STEREOTAXIS INC | $14,286,000 | – | 4,070,000 | +100.0% | 5.17% | – |
| EPZM | EPIZYME INC | $14,080,000 | -17.8% | 1,365,000 | 0.0% | 5.09% | -2.5% | |
| IMMY | Buy | HARROW HEALTH | $13,319,000 | -30.7% | 2,370,000 | +7.2% | 4.82% | -17.8% |
| EIDX | EIDOS THERAPEUTICS INC | $10,991,000 | +15.7% | 305,550 | 0.0% | 3.97% | +37.3% | |
| TPTX | New | TURNING POINT THERAPEUTICS INC | $10,810,000 | – | 287,500 | +100.0% | 3.91% | – |
| AMRN | AMARIN CORP PLCsponsored adr | $9,778,000 | -21.8% | 645,000 | 0.0% | 3.54% | -7.2% | |
| ODT | Sell | ODONATE THERAPEUTICS INC | $9,111,000 | -41.6% | 350,000 | -17.6% | 3.30% | -30.7% |
| OCUL | Sell | OCULAR THERAPEUTIX INC | $8,436,000 | -35.0% | 2,775,000 | -5.9% | 3.05% | -22.9% |
| AXGN | Sell | AXOGEN INC | $8,376,000 | -53.0% | 700,000 | -22.2% | 3.03% | -44.2% |
| QURE | UNIQURE NV | $8,069,000 | -49.6% | 205,000 | 0.0% | 2.92% | -40.2% | |
| CARA | New | CARA THERAPEUTICS INC | $8,043,000 | – | 440,000 | +100.0% | 2.91% | – |
| BOLD | Buy | AUDENTES THERAPEUTICS INC | $8,006,000 | -24.5% | 285,000 | +1.8% | 2.90% | -10.4% |
| DCPH | Sell | DECIPHERA PHARMACEUTICALS IN | $7,806,000 | +11.7% | 230,000 | -25.8% | 2.82% | +32.5% |
| BPMC | Sell | BLUEPRINT MEDICINES CORP | $7,714,000 | -34.6% | 105,000 | -16.0% | 2.79% | -22.4% |
| Sell | CYTOKINETICS | $7,397,000 | -26.9% | 650,000 | -27.8% | 2.68% | -13.3% | |
| XOMA | Sell | XOMA CORP DEL | $7,391,000 | +24.3% | 375,000 | -6.2% | 2.67% | +47.5% |
| ETON | Buy | ETON PHARMACEUTICALS INC | $7,363,000 | -13.3% | 1,165,000 | +8.4% | 2.66% | +2.9% |
| ACAD | ACADIA PHARMACEUTICALS INC | $7,198,000 | +34.6% | 200,000 | 0.0% | 2.60% | +59.8% | |
| CERC | CERECOR INC | $7,190,000 | -35.7% | 2,185,536 | 0.0% | 2.60% | -23.7% | |
| BHVN | Buy | BIOHAVEN PHARMACEUTICAL HLDG | $6,675,000 | +1.6% | 160,000 | +6.7% | 2.41% | +20.6% |
| PTCT | Sell | PTC THERAPEUTICS INC | $6,426,000 | -36.9% | 190,000 | -16.1% | 2.32% | -25.2% |
| TCDA | TRICIDA INC | $6,020,000 | -21.8% | 195,000 | 0.0% | 2.18% | -7.2% | |
| ATXI | Buy | AVENUE THERAPEUTICS INC | $5,677,000 | -3.1% | 952,600 | +2.4% | 2.05% | +14.9% |
| FGEN | FIBROGEN INC | $5,547,000 | -18.1% | 150,000 | 0.0% | 2.01% | -2.9% | |
| SWAV | New | SHOCKWAVE MED INC | $4,789,000 | – | 160,000 | +100.0% | 1.73% | – |
| ZYME | ZYMEWORKS INC | $4,216,000 | +12.6% | 170,000 | 0.0% | 1.52% | +33.7% | |
| QTRX | New | QUANTERIX CORP | $4,063,000 | – | 185,000 | +100.0% | 1.47% | – |
| MGTA | Sell | MAGENTA THERAPEUTICS INC | $3,950,000 | -49.9% | 385,000 | -28.0% | 1.43% | -40.6% |
| TGTX | Sell | TG THERAPEUTICS INC | $3,439,000 | -65.4% | 612,500 | -46.7% | 1.24% | -59.0% |
| RARX | Buy | RA PHARMACEUTICALS INC | $3,354,000 | +118.6% | 141,800 | +178.0% | 1.21% | +159.2% |
| CRNX | Buy | CRINETICS PHARMACEUTICALS INC | $3,113,000 | +245.9% | 207,000 | +475.0% | 1.13% | +310.9% |
| THOR | Buy | SYNTHORX INC | $2,929,000 | +37.6% | 180,000 | +14.2% | 1.06% | +63.2% |
| NLTX | New | NEOLEUKIN THERAPEUTICS INC | $2,836,000 | – | 995,000 | +100.0% | 1.03% | – |
| FTSV | New | FORTY SEVEN INC | $2,729,000 | – | 425,000 | +100.0% | 0.99% | – |
| NXTC | New | NEXTCURE INC | $2,622,000 | – | 85,000 | +100.0% | 0.95% | – |
| Sell | FORTRESS BIOTECH INC | $2,334,000 | -34.2% | 1,655,000 | -30.0% | 0.84% | -21.9% | |
| RDUS | New | RADIUS HEALTH INC | $1,931,000 | – | 75,000 | +100.0% | 0.70% | – |
| New | APTOSE BIOSCIENCES INC | $1,501,000 | – | 720,000 | +100.0% | 0.54% | – | |
| FLXN | New | FLEXION THERAPEUTICS INC | $1,439,000 | – | 105,000 | +100.0% | 0.52% | – |
| CCXI | New | CHEMOCENTRYX INC | $1,356,000 | – | 200,000 | +100.0% | 0.49% | – |
| EDAP | New | EDAP TMS SAsponsored adr | $1,347,000 | – | 300,000 | +100.0% | 0.49% | – |
| ITCI | New | INTRA CELLULAR THERAPIES INC | $1,270,000 | – | 170,000 | +100.0% | 0.46% | – |
| SBBP | Sell | STRONGBRIDGE BIOPHARMA PLC | $1,171,000 | -67.2% | 490,000 | -57.0% | 0.42% | -61.1% |
| CBAY | New | CYMABAY THERAPEUTICS INC | $717,000 | – | 140,000 | +100.0% | 0.26% | – |
| VRML | Sell | VERMILLION INC | $661,000 | -82.5% | 1,265,000 | -70.2% | 0.24% | -79.3% |
| ASMB | New | ASSEMBLY BIOSCIENCES INC | $492,000 | – | 50,000 | +100.0% | 0.18% | – |
| BLRX | Sell | BIOLINERX LTDsponsored adr | $44,000 | -51.6% | 16,667 | -93.3% | 0.02% | -42.9% |
| PRTO | New | PROTEON THERAPEUTICS INC | $14,000 | – | 54,000 | +100.0% | 0.01% | – |
| AZRX | Exit | AZURRX BIOPHARMA INC | $0 | – | -145,000 | -100.0% | -0.08% | – |
| PLX | Exit | PROTALIX BIOTHERAPEUTICS INC | $0 | – | -1,000,000 | -100.0% | -0.14% | – |
| ARQL | Exit | ARQULE INC | $0 | – | -100,000 | -100.0% | -0.34% | – |
| FENC | Exit | FENNEC PHARMACEUTICALS INC | $0 | – | -295,000 | -100.0% | -0.36% | – |
| AQST | Exit | AQUESTIVE THERAPEUTICS INC | $0 | – | -590,000 | -100.0% | -0.76% | – |
| AIMT | Exit | AIMMUNE THERAPEUTICS INC | $0 | – | -130,000 | -100.0% | -0.82% | – |
| VKTX | Exit | VIKING THERAPEUTICS INC | $0 | – | -400,000 | -100.0% | -1.01% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -220,000 | -100.0% | -1.48% | – |
| IRWD | Exit | IRONWOOD PHARMACEUTICAL INC | $0 | – | -525,400 | -100.0% | -1.75% | – |
| CMRX | Exit | CHIMERIX INC | $0 | – | -1,470,000 | -100.0% | -1.94% | – |
| LXRX | Exit | LEXICON PHARMACEUTICALS INC | $0 | – | -1,480,000 | -100.0% | -2.84% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| CODEXIS INC | 39 | Q3 2023 | 10.9% |
| CHIMERIX INC | 31 | Q3 2022 | 16.4% |
| XOMA CORP DEL | 27 | Q3 2023 | 3.6% |
| FIBROGEN INC | 26 | Q1 2021 | 6.8% |
| BIOLINERX LTD (Does not reflect a reverse stock split effectuated after June 30, 2019) | 26 | Q1 2020 | 2.4% |
| OCULAR THERAPEUTIX INC | 24 | Q3 2023 | 17.6% |
| AXOGEN INC | 20 | Q4 2019 | 18.7% |
| ETON PHARMACEUTICALS INC | 20 | Q3 2023 | 5.6% |
| AMARIN CORP PLC | 20 | Q4 2020 | 6.6% |
| IMPRIMIS PHARMACEUTICALS INC | 19 | Q1 2020 | 5.9% |
View Opaleye Management Inc.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| CHIMERIX INCSold out | February 13, 2023 | 0 | 0.0% |
| Larimar Therapeutics, Inc. | January 23, 2023 | 1,560,000 | 3.6% |
| TELA Bio, Inc. | June 10, 2022 | 1,557,500 | 10.7% |
| Gemini Therapeutics, Inc. /DESold out | February 01, 2022 | 0 | 0.0% |
| Adamas Pharmaceuticals IncSold out | January 26, 2022 | 0 | 0.0% |
| AVENUE THERAPEUTICS, INC. | February 12, 2021 | 9 | 11.0% |
| Cardiff Oncology, Inc. | February 12, 2021 | 9 | 11.0% |
| EDAP TMS SA | February 12, 2021 | 9 | 11.0% |
| Fortress Biotech, Inc. | February 12, 2021 | 9 | 11.0% |
| Gemini Therapeutics, Inc. /DE | February 12, 2021 | 9 | 11.0% |
View Opaleye Management Inc.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 4 | 2024-04-25 |
| 4 | 2024-04-24 |
| 4 | 2024-04-19 |
| SC 13G/A | 2024-04-09 |
| SC 13G | 2024-04-08 |
| 4 | 2024-03-28 |
| 4 | 2024-03-22 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Opaleye Management Inc.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.