$4.16 Billion is the total value of Rock Springs Capital Management LP's 120 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 9.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HUM | HUMANA INC | $218,449,035 | +5.6% | 426,500 | 0.0% | 5.26% | -1.7% | |
| IMCR | Sell | IMMUNOCORE HLDGS PLCads | $189,533,237 | +15.6% | 3,321,066 | -4.9% | 4.56% | +7.7% |
| PODD | Buy | INSULET CORP | $154,333,958 | +29.8% | 524,250 | +1.1% | 3.71% | +20.9% |
| UNH | Buy | UNITEDHEALTH GROUP INC | $143,148,600 | +5.2% | 270,000 | +0.2% | 3.44% | -2.0% |
| NBIX | NEUROCRINE BIOSCIENCES INC | $134,071,400 | +12.5% | 1,122,500 | 0.0% | 3.23% | +4.8% | |
| ARGX | ARGENX SEsponsored adr | $132,590,500 | +7.3% | 350,000 | 0.0% | 3.19% | -0.1% | |
| AGL | Buy | AGILON HEALTH INC | $127,062,150 | -30.0% | 7,872,500 | +1.6% | 3.06% | -34.8% |
| RXDX | Buy | PROMETHEUS BIOSCIENCES INC | $113,470,500 | +197.9% | 1,031,550 | +59.8% | 2.73% | +177.4% |
| PEN | Buy | PENUMBRA INC | $113,065,295 | +25.3% | 508,250 | +6.8% | 2.72% | +16.7% |
| EVH | Buy | EVOLENT HEALTH INCcl a | $106,802,280 | -8.9% | 3,803,500 | +16.6% | 2.57% | -15.1% |
| MDGL | Buy | MADRIGAL PHARMACEUTICALS INC | $101,042,120 | +389.7% | 348,121 | +9.6% | 2.43% | +356.1% |
| IDXX | Sell | IDEXX LABS INC | $84,651,700 | +15.8% | 207,500 | -7.5% | 2.04% | +7.9% |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $84,177,860 | +87.1% | 739,700 | +1.7% | 2.03% | +74.4% |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $84,144,303 | -2.7% | 2,996,592 | -2.0% | 2.02% | -9.4% |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $82,867,053 | -18.2% | 1,891,510 | +23.0% | 1.99% | -23.8% |
| KRTX | KARUNA THERAPEUTICS INC | $81,304,233 | -12.6% | 413,762 | 0.0% | 1.96% | -18.6% | |
| ISRG | INTUITIVE SURGICAL INC | $79,206,975 | +41.6% | 298,500 | 0.0% | 1.91% | +31.9% | |
| CERE | Buy | CEREVEL THERAPEUTICS HLDNG I | $79,053,875 | +11.9% | 2,506,464 | +0.3% | 1.90% | +4.3% |
| ALNY | ALNYLAM PHARMACEUTICALS INC | $79,018,625 | +18.7% | 332,500 | 0.0% | 1.90% | +10.6% | |
| AKRO | Buy | AKERO THERAPEUTICS INC | $76,755,839 | +64.5% | 1,400,654 | +2.2% | 1.85% | +53.3% |
| ACHC | Buy | ACADIA HEALTHCARE COMPANY IN | $69,601,560 | +5.4% | 845,500 | +0.1% | 1.68% | -1.8% |
| ALGN | Sell | ALIGN TECHNOLOGY INC | $63,765,615 | -10.5% | 302,350 | -12.1% | 1.53% | -16.6% |
| ACRS | ACLARIS THERAPEUTICS INC | $62,389,672 | +0.1% | 3,961,249 | 0.0% | 1.50% | -6.8% | |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $59,778,626 | +21.5% | 1,290,279 | +8.6% | 1.44% | +13.1% |
| BAX | Buy | BAXTER INTL INC | $58,615,500 | +44.1% | 1,150,000 | +52.2% | 1.41% | +34.2% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $56,496,880 | +18.9% | 436,000 | +1.4% | 1.36% | +10.7% |
| DXCM | DEXCOM INC | $55,544,220 | +40.6% | 490,500 | 0.0% | 1.34% | +31.1% | |
| ASND | ASCENDIS PHARMA A/Ssponsored adr | $51,966,315 | +18.3% | 425,500 | 0.0% | 1.25% | +10.1% | |
| SGEN | Buy | SEAGEN INC | $51,429,702 | +38.2% | 400,200 | +47.1% | 1.24% | +28.8% |
| RYTM | RHYTHM PHARMACEUTICALS INC | $51,276,389 | +18.9% | 1,760,865 | 0.0% | 1.23% | +10.8% | |
| EW | Buy | EDWARDS LIFESCIENCES CORP | $48,190,599 | -7.6% | 645,900 | +2.4% | 1.16% | -13.9% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $46,356,747 | +11.1% | 1,175,672 | +1.7% | 1.12% | +3.4% |
| Buy | AMYLYX PHARMACEUTICALS INC | $45,435,087 | +299.8% | 1,229,637 | +204.6% | 1.09% | +271.8% | |
| PRTA | Buy | PROTHENA CORP PLC | $45,396,086 | +10.4% | 753,462 | +11.1% | 1.09% | +2.8% |
| EXAS | Buy | EXACT SCIENCES CORP | $43,940,125 | +133.7% | 887,500 | +53.4% | 1.06% | +117.5% |
| WST | Buy | WEST PHARMACEUTICAL SVSC INC | $43,657,425 | -1.7% | 185,500 | +2.8% | 1.05% | -8.5% |
| NVRO | Buy | NEVRO CORP | $42,684,840 | +16.4% | 1,077,900 | +37.0% | 1.03% | +8.4% |
| PHR | PHREESIA INC | $42,148,900 | +27.0% | 1,302,500 | 0.0% | 1.01% | +18.3% | |
| PCRX | Buy | PACIRA BIOSCIENCES INC | $39,868,686 | -26.3% | 1,032,600 | +1.5% | 0.96% | -31.4% |
| OLK | OLINK HLDG ABsponsored ads | $36,674,100 | +109.1% | 1,445,000 | 0.0% | 0.88% | +94.7% | |
| MRTX | Sell | MIRATI THERAPEUTICS INC | $36,475,637 | -39.7% | 805,024 | -7.1% | 0.88% | -43.9% |
| MIRM | MIRUM PHARMACEUTICALS INC | $35,016,794 | -7.2% | 1,795,733 | 0.0% | 0.84% | -13.4% | |
| FRPT | Sell | FRESHPET INC | $34,669,890 | -1.1% | 657,000 | -6.1% | 0.83% | -7.9% |
| ABCM | Buy | ABCAM PLCads | $33,920,800 | +11.3% | 2,180,000 | +7.3% | 0.82% | +3.7% |
| ZLAB | Sell | ZAI LAB LTDadr | $32,532,790 | -20.2% | 1,059,700 | -11.1% | 0.78% | -25.6% |
| KYMR | Buy | KYMERA THERAPEUTICS INC | $30,645,364 | +34.5% | 1,227,779 | +17.3% | 0.74% | +25.1% |
| IRTC | Buy | IRHYTHM TECHNOLOGIES INC | $28,986,182 | -21.1% | 309,450 | +5.5% | 0.70% | -26.6% |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $27,373,105 | +22.1% | 264,500 | 0.0% | 0.66% | +13.8% | |
| XLV | SELECT SECTOR SPDR TRsbi healthcare | $27,170,000 | +12.2% | 200,000 | 0.0% | 0.65% | +4.5% | |
| CMPX | COMPASS THERAPEUTICS INC | $26,825,936 | +120.6% | 5,333,188 | 0.0% | 0.64% | +105.4% | |
| MRSN | Buy | MERSANA THERAPEUTICS INC | $24,048,286 | -12.7% | 4,103,803 | +0.7% | 0.58% | -18.7% |
| SWAV | Sell | SHOCKWAVE MED INC | $23,665,711 | -52.7% | 115,100 | -36.1% | 0.57% | -56.0% |
| LEGN | LEGEND BIOTECH CORPsponsored ads | $22,487,263 | +22.4% | 450,466 | 0.0% | 0.54% | +13.9% | |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $21,705,661 | +0.6% | 1,890,737 | +10.4% | 0.52% | -6.3% |
| BRKS | Buy | AZENTA INC | $20,464,330 | +44.6% | 351,500 | +6.5% | 0.49% | +34.4% |
| CYTK | CYTOKINETICS INC | $20,298,260 | -5.4% | 443,000 | 0.0% | 0.49% | -11.9% | |
| TVTX | TRAVERE THERAPEUTICS INC | $20,013,200 | -14.7% | 951,650 | 0.0% | 0.48% | -20.5% | |
| IMTX | Buy | IMMATICS N.V | $19,813,369 | +17.9% | 2,274,784 | +35.3% | 0.48% | +9.9% |
| DVAX | Buy | DYNAVAX TECHNOLOGIES CORP | $19,298,385 | +9.8% | 1,813,758 | +7.7% | 0.46% | +2.2% |
| CLDX | Sell | CELLDEX THERAPEUTICS INC NEW | $18,786,433 | +58.5% | 421,504 | -0.0% | 0.45% | +47.7% |
| CNMD | Sell | CONMED CORP | $18,171,200 | -2.7% | 205,000 | -12.0% | 0.44% | -9.3% |
| ANAB | ANAPTYSBIO INC | $17,868,834 | +21.5% | 576,600 | 0.0% | 0.43% | +13.2% | |
| COLL | COLLEGIUM PHARMACEUTICAL INC | $16,820,000 | +44.8% | 725,000 | 0.0% | 0.40% | +35.0% | |
| Sell | WARBY PARKER INC | $16,443,973 | -5.9% | 1,218,975 | -6.9% | 0.40% | -12.2% | |
| ACCD | Sell | ACCOLADE INC | $15,097,020 | -41.9% | 1,938,000 | -14.8% | 0.36% | -45.9% |
| Sell | CINCOR PHARMA INC | $13,722,744 | -65.3% | 1,116,578 | -7.4% | 0.33% | -67.7% | |
| LFST | Buy | LIFESTANCE HEALTH GROUP INC | $13,338,000 | +0.7% | 2,700,000 | +35.0% | 0.32% | -6.1% |
| KDNY | CHINOOK THERAPEUTICS INC | $13,296,814 | +33.3% | 507,512 | 0.0% | 0.32% | +24.0% | |
| FOLD | Buy | AMICUS THERAPEUTICS INC | $12,989,071 | +22.9% | 1,063,806 | +5.1% | 0.31% | +14.7% |
| VERV | VERVE THERAPEUTICS INC | $10,813,496 | -43.7% | 558,837 | 0.0% | 0.26% | -47.6% | |
| Buy | AURA BIOSCIENCES INC | $10,707,449 | -41.8% | 1,019,757 | +0.4% | 0.26% | -45.7% | |
| RLAY | Buy | RELAY THERAPEUTICS INC | $10,069,052 | -27.2% | 673,966 | +9.0% | 0.24% | -32.2% |
| HCAT | Buy | HEALTH CATALYST INC | $9,884,837 | +15.8% | 929,900 | +5.7% | 0.24% | +8.2% |
| AMYT | AMRYT PHARMA PLCsponsored ads | $9,677,063 | +5.5% | 1,325,625 | 0.0% | 0.23% | -1.7% | |
| EDAP | EDAP TMS S Asponsored adr | $9,700,600 | +29.2% | 910,000 | 0.0% | 0.23% | +20.1% | |
| Buy | BIOHAVEN LTD | $9,284,512 | +780.0% | 668,913 | +299.5% | 0.22% | +725.9% | |
| NVCR | Sell | NOVOCURE LTD | $9,168,750 | -31.0% | 125,000 | -28.6% | 0.22% | -35.6% |
| MGNX | Sell | MACROGENICS INC | $7,535,974 | +80.5% | 1,123,096 | -6.9% | 0.18% | +67.6% |
| New | DISC MEDICINE INC | $6,752,595 | – | 339,497 | +100.0% | 0.16% | – | |
| ICOSAVAX INC | $6,201,140 | +151.3% | 781,000 | 0.0% | 0.15% | +132.8% | ||
| BMEA | BIOMEA FUSION INC | $6,161,032 | -13.8% | 730,846 | 0.0% | 0.15% | -20.0% | |
| VIGIL NEUROSCIENCE INC | $5,899,475 | +37.4% | 471,958 | 0.0% | 0.14% | +27.9% | ||
| NVTA | Sell | INVITAE CORP | $5,761,397 | -30.9% | 3,097,525 | -8.5% | 0.14% | -35.3% |
| LUNG | Buy | PULMONX CORP | $5,499,732 | -44.7% | 652,400 | +9.2% | 0.13% | -48.6% |
| NVAX | Sell | NOVAVAX INC | $5,475,128 | -49.8% | 532,600 | -11.1% | 0.13% | -53.2% |
| GH | GUARDANT HEALTH INC | $5,440,000 | -49.5% | 200,000 | 0.0% | 0.13% | -52.9% | |
| GMDA | GAMIDA CELL LTD | $5,314,649 | -18.9% | 4,119,883 | 0.0% | 0.13% | -24.3% | |
| FSTX | F-STAR THERAPEUTICS INC | $4,751,938 | +23.4% | 751,889 | 0.0% | 0.11% | +15.2% | |
| DSGN | DESIGN THERAPEUTICS INC | $4,723,612 | -38.6% | 460,391 | 0.0% | 0.11% | -42.7% | |
| MREO | MEREO BIOPHARMA GROUP PLCspon ads | $4,683,673 | -12.9% | 6,244,897 | 0.0% | 0.11% | -18.7% | |
| KNTE | KINNATE BIOPHARMA INC | $4,556,535 | -49.0% | 746,973 | 0.0% | 0.11% | -52.4% | |
| BEAM | BEAM THERAPEUTICS INC | $4,358,027 | -17.9% | 111,430 | 0.0% | 0.10% | -23.4% | |
| ADAP | Buy | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $3,907,743 | +54.2% | 2,676,536 | +13.5% | 0.09% | +44.6% |
| XILIO THERAPEUTICS INC | $3,666,142 | -7.6% | 1,362,878 | 0.0% | 0.09% | -13.7% | ||
| ALT | ALTIMMUNE INC | $3,672,545 | +28.8% | 223,255 | 0.0% | 0.09% | +18.9% | |
| PRTK | PARATEK PHARMACEUTICALS INC | $3,242,649 | -27.2% | 1,734,037 | 0.0% | 0.08% | -32.2% | |
| INZY | Buy | INOZYME PHARMA INC | $3,240,328 | -56.9% | 3,086,027 | +9.9% | 0.08% | -59.8% |
| GOSSAMER BIO INCnote 5.000% 6/0 | $3,096,866 | -68.7% | 9,573,000 | 0.0% | 0.08% | -70.6% | ||
| TRAVERE THERAPEUTICS INCnote 2.500% 9/1 | $3,000,075 | -8.8% | 3,250,000 | 0.0% | 0.07% | -15.3% | ||
| FULC | FULCRUM THERAPEUTICS INC | $2,799,815 | -10.0% | 384,590 | 0.0% | 0.07% | -16.2% | |
| RPHM | RENEO PHARMACEUTICALS INC | $2,663,621 | -30.5% | 1,143,185 | 0.0% | 0.06% | -35.4% | |
| NKTX | Sell | NKARTA INC | $2,356,400 | -70.9% | 393,389 | -36.2% | 0.06% | -72.7% |
| THESEUS PHARMACEUTICALS INC | $2,177,898 | -14.2% | 437,329 | 0.0% | 0.05% | -21.2% | ||
| AUPH | Sell | AURINIA PHARMACEUTICALS INC | $2,071,613 | -74.2% | 479,540 | -55.0% | 0.05% | -75.8% |
| SPRB | SPRUCE BIOSCIENCES INC | $1,780,739 | -19.9% | 1,622,689 | 0.0% | 0.04% | -24.6% | |
| LPTX | LEAP THERAPEUTICS INC | $1,646,931 | -48.9% | 3,659,847 | 0.0% | 0.04% | -51.8% | |
| NEUROCRINE BIOSCIENCES INCnote 2.250% 5/1 | $1,586,500 | +12.3% | 1,000,000 | 0.0% | 0.04% | +5.6% | ||
| AGLE | AEGLEA BIOTHERAPEUTICS INC | $1,535,916 | -14.5% | 3,413,906 | 0.0% | 0.04% | -19.6% | |
| EPIX | ESSA PHARMA INC | $1,322,859 | +38.5% | 524,944 | 0.0% | 0.03% | +28.0% | |
| SPRO | Sell | SPERO THERAPEUTICS INC | $1,158,292 | -24.8% | 669,533 | -13.1% | 0.03% | -30.0% |
| FATE | FATE THERAPEUTICS INC | $1,109,900 | -55.0% | 110,000 | 0.0% | 0.03% | -57.8% | |
| TPST | TEMPEST THERAPEUTICS INC | $947,202 | -33.9% | 823,654 | 0.0% | 0.02% | -37.8% | |
| VINC | Sell | VINCERX PHARMA INC | $909,553 | -40.6% | 891,719 | -19.6% | 0.02% | -45.0% |
| CGEN | COMPUGEN LTDord | $923,246 | +8.9% | 1,289,990 | 0.0% | 0.02% | 0.0% | |
| GOSS | Sell | GOSSAMER BIO INC | $816,024 | -95.7% | 376,048 | -76.3% | 0.02% | -95.9% |
| New | ACELRX PHARMACEUTICALS INC | $715,200 | – | 316,460 | +100.0% | 0.02% | – | |
| NEVRO CORPnote 2.750% 4/0 | $458,750 | -3.0% | 500,000 | 0.0% | 0.01% | -8.3% | ||
| APLT | Sell | APPLIED THERAPEUTICS INC | $453,477 | -30.6% | 596,680 | -15.0% | 0.01% | -35.3% |
| BCEL | Sell | ATRECA INC | $290,242 | -60.0% | 362,530 | -21.6% | 0.01% | -63.2% |
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $19,367 | -28.3% | 134,028 | 0.0% | 0.00% | -100.0% | |
| ALT | Exit | ALTIMMUNE INCcall | $0 | – | -33,500 | -100.0% | -0.01% | – |
| PHAS | Exit | PHASEBIO PHARMACEUTICALS INC | $0 | – | -2,719,074 | -100.0% | -0.01% | – |
| ACRX | Exit | ACELRX PHARMACEUTICALS INC | $0 | – | -6,329,202 | -100.0% | -0.03% | – |
| IMRA | Exit | IMARA INC | $0 | – | -842,402 | -100.0% | -0.05% | – |
| JYAC | Exit | JIYA ACQUISITION CORP | $0 | – | -206,200 | -100.0% | -0.05% | – |
| BLSA | Exit | BCLS ACQUISITION CORP | $0 | – | -309,000 | -100.0% | -0.08% | – |
| Exit | EQRX INC | $0 | – | -1,000,000 | -100.0% | -0.13% | – | |
| OHPAU | Exit | ORION ACQUISITION CORPunit 02/19/2026 | $0 | – | -1,000,000 | -100.0% | -0.26% | – |
| ARVN | Exit | ARVINAS INC | $0 | – | -280,100 | -100.0% | -0.32% | – |
| CVET | Exit | COVETRUS INC | $0 | – | -1,678,800 | -100.0% | -0.90% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| INTUITIVE SURGICAL INC | 40 | Q3 2023 | 3.4% |
| NEUROCRINE BIOSCIENCES INC | 39 | Q3 2023 | 4.8% |
| PACIRA PHARMACEUTICALS INC | 39 | Q3 2023 | 2.6% |
| ULTRAGENYX PHARMACEUTICAL IN | 39 | Q3 2023 | 1.9% |
| ACADIA HEALTHCARE COMPANY IN | 38 | Q3 2023 | 4.4% |
| ASCENDIS PHARMA A/S | 35 | Q3 2023 | 1.3% |
| INVITAE CORP | 35 | Q3 2023 | 1.8% |
| BIOMARIN PHARMACEUTICAL INC | 35 | Q3 2023 | 1.3% |
| MACROGENICS INC | 35 | Q3 2023 | 0.5% |
| COLLEGIUM PHARMACEUTICAL INC | 34 | Q3 2023 | 2.1% |
View Rock Springs Capital Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Aeglea BioTherapeutics, Inc. | February 14, 2023 | 3,413,906 | 5.6% |
| Compass Therapeutics, Inc. | February 14, 2023 | 5,333,188 | 4.2% |
| Mirum Pharmaceuticals, Inc. | February 14, 2023 | 1,795,733 | 4.9% |
| PhaseBio Pharmaceuticals IncSold out | February 14, 2023 | 0 | 0.0% |
| Sierra Oncology, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ARDELYX, INC.Sold out | February 15, 2022 | 0 | 0.0% |
| CHIASMA, INCSold out | February 15, 2022 | 0 | 0.0% |
| FIVE PRIME THERAPEUTICS, INC.Sold out | February 15, 2022 | 0 | 0.0% |
| F-star Therapeutics, Inc. | February 15, 2022 | 751,889 | 3.6% |
| Protara Therapeutics, Inc.Sold out | February 15, 2022 | 0 | 0.0% |
View Rock Springs Capital Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-05 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Rock Springs Capital Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.