$4.19 Billion is the total value of Rock Springs Capital Management LP's 121 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 5.8% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| HUM | HUMANA INC | $207,048,690 | -5.2% | 426,500 | 0.0% | 4.94% | -6.0% | |
| AGL | Buy | AGILON HEALTH INC | $187,209,375 | +47.3% | 7,882,500 | +0.1% | 4.47% | +46.1% |
| PODD | Buy | INSULET CORP | $171,201,780 | +10.9% | 536,750 | +2.4% | 4.08% | +10.0% |
| IMCR | Sell | IMMUNOCORE HLDGS PLCads | $148,402,169 | -21.7% | 3,001,662 | -9.6% | 3.54% | -22.4% |
| ARGX | ARGENX SEsponsored adr | $130,403,000 | -1.6% | 350,000 | 0.0% | 3.11% | -2.5% | |
| UNH | UNITEDHEALTH GROUP INC | $127,599,300 | -10.9% | 270,000 | 0.0% | 3.04% | -11.6% | |
| EVH | EVOLENT HEALTH INCcl a | $123,423,575 | +15.6% | 3,803,500 | 0.0% | 2.94% | +14.6% | |
| NBIX | Buy | NEUROCRINE BIOSCIENCES INC | $122,486,322 | -8.6% | 1,210,100 | +7.8% | 2.92% | -9.4% |
| PEN | Sell | PENUMBRA INC | $120,812,115 | +6.9% | 433,500 | -14.7% | 2.88% | +5.9% |
| RXDX | PROMETHEUS BIOSCIENCES INC | $110,705,946 | -2.4% | 1,031,550 | 0.0% | 2.64% | -3.3% | |
| IDXX | IDEXX LABS INC | $103,766,600 | +22.6% | 207,500 | 0.0% | 2.48% | +21.6% | |
| BPMC | Buy | BLUEPRINT MEDICINES CORP | $91,466,830 | +10.4% | 2,033,048 | +7.5% | 2.18% | +9.4% |
| KRTX | Buy | KARUNA THERAPEUTICS INC | $89,644,244 | +10.3% | 493,527 | +19.3% | 2.14% | +9.4% |
| MDGL | MADRIGAL PHARMACEUTICALS INC | $84,335,793 | -16.5% | 348,121 | 0.0% | 2.01% | -17.2% | |
| ALGN | Sell | ALIGN TECHNOLOGY INC | $82,649,529 | +29.6% | 247,350 | -18.2% | 1.97% | +28.6% |
| SGEN | SEAGEN INC | $81,028,494 | +57.6% | 400,200 | 0.0% | 1.93% | +56.1% | |
| HZNP | Buy | HORIZON THERAPEUTICS PUB L | $80,774,514 | -4.0% | 740,100 | +0.1% | 1.93% | -4.9% |
| ISRG | INTUITIVE SURGICAL INC | $76,257,795 | -3.7% | 298,500 | 0.0% | 1.82% | -4.6% | |
| WST | Buy | WEST PHARMACEUTICAL SVSC INC | $69,986,940 | +60.3% | 202,000 | +8.9% | 1.67% | +59.0% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $69,110,400 | -12.5% | 345,000 | +3.8% | 1.65% | -13.3% |
| EXAS | Buy | EXACT SCIENCES CORP | $63,843,115 | +45.3% | 941,500 | +6.1% | 1.52% | +44.1% |
| ACHC | Buy | ACADIA HEALTHCARE COMPANY IN | $62,197,713 | -10.6% | 860,868 | +1.8% | 1.48% | -11.4% |
| CERE | Buy | CEREVEL THERAPEUTICS HLDNG I | $61,314,411 | -22.4% | 2,513,916 | +0.3% | 1.46% | -23.1% |
| AGIO | Sell | AGIOS PHARMACEUTICALS INC | $61,137,067 | -27.3% | 2,661,605 | -11.2% | 1.46% | -28.0% |
| SRPT | Buy | SAREPTA THERAPEUTICS INC | $60,989,775 | +8.0% | 442,500 | +1.5% | 1.46% | +7.1% |
| DXCM | DEXCOM INC | $56,986,290 | +2.6% | 490,500 | 0.0% | 1.36% | +1.7% | |
| AKRO | Buy | AKERO THERAPEUTICS INC | $55,639,758 | -27.5% | 1,454,254 | +3.8% | 1.33% | -28.1% |
| RARE | Buy | ULTRAGENYX PHARMACEUTICAL IN | $53,589,680 | -10.4% | 1,336,401 | +3.6% | 1.28% | -11.1% |
| EW | EDWARDS LIFESCIENCES CORP | $53,435,307 | +10.9% | 645,900 | 0.0% | 1.28% | +9.9% | |
| ASND | ASCENDIS PHARMA A/Ssponsored adr | $45,622,110 | -12.2% | 425,500 | 0.0% | 1.09% | -12.9% | |
| FRPT | Buy | FRESHPET INC | $43,850,875 | +26.5% | 662,500 | +0.8% | 1.05% | +25.4% |
| MIRM | MIRUM PHARMACEUTICALS INC | $43,133,507 | +23.2% | 1,795,733 | 0.0% | 1.03% | +22.1% | |
| Buy | AMYLYX PHARMACEUTICALS INC | $42,625,621 | -6.2% | 1,452,816 | +18.1% | 1.02% | -7.0% | |
| XENE | Buy | XENON PHARMACEUTICALS INC | $42,160,692 | -9.1% | 1,178,002 | +0.2% | 1.01% | -9.8% |
| PCRX | PACIRA BIOSCIENCES INC | $42,140,406 | +5.7% | 1,032,600 | 0.0% | 1.00% | +4.8% | |
| PHR | PHREESIA INC | $42,057,725 | -0.2% | 1,302,500 | 0.0% | 1.00% | -1.1% | |
| BMEA | Buy | BIOMEA FUSION INC | $40,226,575 | +552.9% | 1,297,213 | +77.5% | 0.96% | +548.6% |
| MRTX | Buy | MIRATI THERAPEUTICS INC | $39,606,404 | +8.6% | 1,065,261 | +32.3% | 0.94% | +7.6% |
| NVRO | NEVRO CORP | $38,966,085 | -8.7% | 1,077,900 | 0.0% | 0.93% | -9.4% | |
| IRTC | IRHYTHM TECHNOLOGIES INC | $38,381,084 | +32.4% | 309,450 | 0.0% | 0.92% | +31.4% | |
| OLK | Buy | OLINK HLDG ABsponsored ads | $37,174,500 | +1.4% | 1,650,000 | +14.2% | 0.89% | +0.6% |
| ACCD | Buy | ACCOLADE INC | $36,597,100 | +142.4% | 2,545,000 | +31.3% | 0.87% | +140.5% |
| PRTA | PROTHENA CORP PLC | $36,520,303 | -19.6% | 753,462 | 0.0% | 0.87% | -20.2% | |
| KYMR | Buy | KYMERA THERAPEUTICS INC | $36,396,870 | +18.8% | 1,228,379 | +0.0% | 0.87% | +17.8% |
| ZLAB | ZAI LAB LTDadr | $35,245,622 | +8.3% | 1,059,700 | 0.0% | 0.84% | +7.4% | |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $32,051,358 | -48.6% | 3,961,849 | +0.0% | 0.76% | -49.0% |
| ABCM | Buy | ABCAM PLCads | $30,184,050 | -11.0% | 2,242,500 | +2.9% | 0.72% | -11.8% |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $28,711,859 | +43.5% | 1,276,650 | +34.2% | 0.68% | +42.1% |
| RYTM | Sell | RHYTHM PHARMACEUTICALS INC | $28,492,674 | -44.4% | 1,597,123 | -9.3% | 0.68% | -44.9% |
| XLV | SELECT SECTOR SPDR TRsbi healthcare | $25,892,000 | -4.7% | 200,000 | 0.0% | 0.62% | -5.5% | |
| BMRN | BIOMARIN PHARMACEUTICAL INC | $25,719,980 | -6.0% | 264,500 | 0.0% | 0.61% | -6.8% | |
| SWAV | SHOCKWAVE MED INC | $24,957,133 | +5.5% | 115,100 | 0.0% | 0.60% | +4.6% | |
| LEGN | Buy | LEGEND BIOTECH CORPsponsored ads | $22,097,538 | -1.7% | 458,265 | +1.7% | 0.53% | -2.6% |
| LFST | Buy | LIFESTANCE HEALTH GROUP INC | $21,547,000 | +61.5% | 2,900,000 | +7.4% | 0.51% | +60.1% |
| CNMD | CONMED CORP | $21,291,300 | +17.2% | 205,000 | 0.0% | 0.51% | +16.2% | |
| BCRX | Buy | BIOCRYST PHARMACEUTICALS INC | $19,466,269 | -10.3% | 2,334,085 | +23.4% | 0.46% | -11.1% |
| AMYT | AMRYT PHARMA PLCsponsored ads | $19,327,613 | +99.7% | 1,325,625 | 0.0% | 0.46% | +97.9% | |
| BRKS | Buy | AZENTA INC | $19,240,144 | -6.0% | 431,200 | +22.7% | 0.46% | -6.7% |
| INZY | Buy | INOZYME PHARMA INC | $18,421,377 | +468.5% | 3,214,900 | +4.2% | 0.44% | +464.1% |
| New | MINERALYS THERAPEUTICS INC | $18,282,925 | – | 1,167,492 | +100.0% | 0.44% | – | |
| CMPX | Buy | COMPASS THERAPEUTICS INC | $18,030,087 | -32.8% | 5,513,788 | +3.4% | 0.43% | -33.3% |
| DVAX | DYNAVAX TECHNOLOGIES CORP | $17,792,966 | -7.8% | 1,813,758 | 0.0% | 0.42% | -8.4% | |
| IMTX | Buy | IMMATICS N.V | $17,346,069 | -12.5% | 2,513,923 | +10.5% | 0.41% | -13.2% |
| MRSN | MERSANA THERAPEUTICS INC | $16,866,630 | -29.9% | 4,103,803 | 0.0% | 0.40% | -30.6% | |
| CYTK | Buy | CYTOKINETICS INC | $15,751,044 | -22.4% | 447,600 | +1.0% | 0.38% | -23.0% |
| COLL | Sell | COLLEGIUM PHARMACEUTICAL INC | $15,593,500 | -7.3% | 650,000 | -10.3% | 0.37% | -8.1% |
| RVMD | New | REVOLUTION MEDICINES INC | $15,220,742 | – | 702,712 | +100.0% | 0.36% | – |
| CLDX | CELLDEX THERAPEUTICS INC NEW | $15,165,714 | -19.3% | 421,504 | 0.0% | 0.36% | -19.9% | |
| Buy | WARBY PARKER INC | $13,767,000 | -16.3% | 1,300,000 | +6.6% | 0.33% | -17.2% | |
| PLRX | New | PLIANT THERAPEUTICS INC | $13,066,479 | – | 491,221 | +100.0% | 0.31% | – |
| ANAB | ANAPTYSBIO INC | $12,546,816 | -29.8% | 576,600 | 0.0% | 0.30% | -30.5% | |
| FOLD | AMICUS THERAPEUTICS INC | $11,797,609 | -9.2% | 1,063,806 | 0.0% | 0.28% | -10.2% | |
| KDNY | CHINOOK THERAPEUTICS INC | $11,748,903 | -11.6% | 507,512 | 0.0% | 0.28% | -12.5% | |
| EDAP | Buy | EDAP TMS S Asponsored adr | $11,402,100 | +17.5% | 1,030,000 | +13.2% | 0.27% | +16.7% |
| RLAY | RELAY THERAPEUTICS INC | $11,100,220 | +10.2% | 673,966 | 0.0% | 0.26% | +9.5% | |
| HCAT | HEALTH CATALYST INC | $10,851,933 | +9.8% | 929,900 | 0.0% | 0.26% | +8.8% | |
| AURA BIOSCIENCES INC | $9,463,345 | -11.6% | 1,019,757 | 0.0% | 0.23% | -12.4% | ||
| Buy | BIOHAVEN LTD | $9,365,610 | +0.9% | 685,623 | +2.5% | 0.22% | 0.0% | |
| VERV | VERVE THERAPEUTICS INC | $8,058,430 | -25.5% | 558,837 | 0.0% | 0.19% | -26.2% | |
| MGNX | MACROGENICS INC | $8,052,598 | +6.9% | 1,123,096 | 0.0% | 0.19% | +6.1% | |
| NVCR | NOVOCURE LTD | $7,517,500 | -18.0% | 125,000 | 0.0% | 0.18% | -19.0% | |
| LUNG | PULMONX CORP | $7,293,832 | +32.6% | 652,400 | 0.0% | 0.17% | +31.8% | |
| RPHM | RENEO PHARMACEUTICALS INC | $6,836,246 | +156.7% | 1,143,185 | 0.0% | 0.16% | +154.7% | |
| Sell | DISC MEDICINE INC | $6,642,387 | -1.6% | 313,468 | -7.7% | 0.16% | -2.5% | |
| SPRB | Buy | SPRUCE BIOSCIENCES INC | $6,029,156 | +238.6% | 2,728,125 | +68.1% | 0.14% | +234.9% |
| AUPH | AURINIA PHARMACEUTICALS INC | $5,255,758 | +153.7% | 479,540 | 0.0% | 0.12% | +150.0% | |
| Buy | ICOSAVAX INC | $5,014,158 | -19.1% | 864,510 | +10.7% | 0.12% | -19.5% | |
| GH | GUARDANT HEALTH INC | $4,688,000 | -13.8% | 200,000 | 0.0% | 0.11% | -14.5% | |
| KNTE | KINNATE BIOPHARMA INC | $4,668,581 | +2.5% | 746,973 | 0.0% | 0.11% | +0.9% | |
| VIGIL NEUROSCIENCE INC | $4,620,469 | -21.7% | 471,958 | 0.0% | 0.11% | -22.5% | ||
| Buy | XILIO THERAPEUTICS INC | $4,567,206 | +24.6% | 1,440,759 | +5.7% | 0.11% | +23.9% | |
| PRTK | PARATEK PHARMACEUTICALS INC | $4,404,454 | +35.8% | 1,734,037 | 0.0% | 0.10% | +34.6% | |
| MREO | MEREO BIOPHARMA GROUP PLCspon ads | $4,414,518 | -5.7% | 6,244,897 | 0.0% | 0.10% | -7.1% | |
| NVTA | Buy | INVITAE CORP | $4,375,924 | -24.0% | 3,241,425 | +4.6% | 0.10% | -25.2% |
| THESEUS PHARMACEUTICALS INC | $3,883,482 | +78.3% | 437,329 | 0.0% | 0.09% | +78.8% | ||
| NVAX | Buy | NOVAVAX INC | $3,710,322 | -32.2% | 535,400 | +0.5% | 0.09% | -32.6% |
| FATE | Buy | FATE THERAPEUTICS INC | $3,489,626 | +214.4% | 612,215 | +456.6% | 0.08% | +207.4% |
| BEAM | BEAM THERAPEUTICS INC | $3,411,987 | -21.7% | 111,430 | 0.0% | 0.08% | -22.9% | |
| TRAVERE THERAPEUTICS INCnote 2.500% 9/1 | $3,126,481 | +4.2% | 3,250,000 | 0.0% | 0.08% | +4.2% | ||
| ADAP | Buy | ADAPTIMMUNE THERAPEUTICS PLCsponds adr | $3,038,751 | -22.2% | 2,787,845 | +4.2% | 0.07% | -22.3% |
| GOSSAMER BIO INCnote 5.000% 6/0 | $2,641,308 | -14.7% | 9,573,000 | 0.0% | 0.06% | -16.0% | ||
| DSGN | DESIGN THERAPEUTICS INC | $2,656,456 | -43.8% | 460,391 | 0.0% | 0.06% | -44.7% | |
| ETNB | New | 89BIO INCcall | $2,505,335 | – | 164,500 | +100.0% | 0.06% | – |
| FULC | Buy | FULCRUM THERAPEUTICS INC | $2,073,868 | -25.9% | 727,673 | +89.2% | 0.05% | -26.9% |
| TPST | TEMPEST THERAPEUTICS INC | $1,910,877 | +101.7% | 823,654 | 0.0% | 0.05% | +100.0% | |
| GMDA | Sell | GAMIDA CELL LTD | $1,899,166 | -64.3% | 2,344,649 | -43.1% | 0.04% | -64.8% |
| LPTX | Buy | LEAP THERAPEUTICS INC | $1,582,763 | -3.9% | 4,655,186 | +27.2% | 0.04% | -5.0% |
| EPIX | ESSA PHARMA INC | $1,559,084 | +17.9% | 524,944 | 0.0% | 0.04% | +15.6% | |
| NKTX | NKARTA INC | $1,396,531 | -40.7% | 393,389 | 0.0% | 0.03% | -42.1% | |
| GOSS | Buy | GOSSAMER BIO INC | $1,386,345 | +69.9% | 1,100,274 | +192.6% | 0.03% | +65.0% |
| NEUROCRINE BIOSCIENCES INCnote 2.250% 5/1 | $1,351,500 | -14.8% | 1,000,000 | 0.0% | 0.03% | -15.8% | ||
| AGLE | AEGLEA BIOTHERAPEUTICS INC | $990,033 | -35.5% | 3,413,906 | 0.0% | 0.02% | -35.1% | |
| SPRO | SPERO THERAPEUTICS INC | $970,823 | -16.2% | 669,533 | 0.0% | 0.02% | -17.9% | |
| ALT | ALTIMMUNE INC | $942,136 | -74.3% | 223,255 | 0.0% | 0.02% | -75.0% | |
| CGEN | COMPUGEN LTDord | $905,573 | -1.9% | 1,289,990 | 0.0% | 0.02% | 0.0% | |
| VINC | VINCERX PHARMA INC | $927,388 | +2.0% | 891,719 | 0.0% | 0.02% | 0.0% | |
| APLT | Buy | APPLIED THERAPEUTICS INC | $633,300 | +39.7% | 780,791 | +30.9% | 0.02% | +36.4% |
| NEVRO CORPnote 2.750% 4/0 | $470,000 | +2.5% | 500,000 | 0.0% | 0.01% | 0.0% | ||
| BCEL | ATRECA INC | $413,284 | +42.4% | 362,530 | 0.0% | 0.01% | +42.9% | |
| ACELRX PHARMACEUTICALS INC | $208,231 | -70.9% | 316,460 | 0.0% | 0.01% | -70.6% | ||
| NUVBWS | NUVATION BIO INC*w exp 07/07/202 | $16,083 | -17.0% | 134,028 | 0.0% | 0.00% | – | |
| FSTX | Exit | F-STAR THERAPEUTICS INC | $0 | – | -751,889 | -100.0% | -0.11% | – |
| Exit | CINCOR PHARMA INC | $0 | – | -1,116,578 | -100.0% | -0.33% | – | |
| BAX | Exit | BAXTER INTL INC | $0 | – | -1,150,000 | -100.0% | -1.41% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| INTUITIVE SURGICAL INC | 40 | Q3 2023 | 3.4% |
| NEUROCRINE BIOSCIENCES INC | 39 | Q3 2023 | 4.8% |
| PACIRA PHARMACEUTICALS INC | 39 | Q3 2023 | 2.6% |
| ULTRAGENYX PHARMACEUTICAL IN | 39 | Q3 2023 | 1.9% |
| ACADIA HEALTHCARE COMPANY IN | 38 | Q3 2023 | 4.4% |
| ASCENDIS PHARMA A/S | 35 | Q3 2023 | 1.3% |
| INVITAE CORP | 35 | Q3 2023 | 1.8% |
| BIOMARIN PHARMACEUTICAL INC | 35 | Q3 2023 | 1.3% |
| MACROGENICS INC | 35 | Q3 2023 | 0.5% |
| COLLEGIUM PHARMACEUTICAL INC | 34 | Q3 2023 | 2.1% |
View Rock Springs Capital Management LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Aeglea BioTherapeutics, Inc. | February 14, 2023 | 3,413,906 | 5.6% |
| Compass Therapeutics, Inc. | February 14, 2023 | 5,333,188 | 4.2% |
| Mirum Pharmaceuticals, Inc. | February 14, 2023 | 1,795,733 | 4.9% |
| PhaseBio Pharmaceuticals IncSold out | February 14, 2023 | 0 | 0.0% |
| Sierra Oncology, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ARDELYX, INC.Sold out | February 15, 2022 | 0 | 0.0% |
| CHIASMA, INCSold out | February 15, 2022 | 0 | 0.0% |
| FIVE PRIME THERAPEUTICS, INC.Sold out | February 15, 2022 | 0 | 0.0% |
| F-star Therapeutics, Inc. | February 15, 2022 | 751,889 | 3.6% |
| Protara Therapeutics, Inc.Sold out | February 15, 2022 | 0 | 0.0% |
View Rock Springs Capital Management LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-04-05 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View Rock Springs Capital Management LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.