$466 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 64 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 59.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Sell | INVESCO QQQ TRput | $55,918,800 | -35.7% | 210,000 | -35.5% | 12.00% | -0.6% | |
| AZN | Sell | ASTRAZENECA PLCsponsored adr | $27,124,068 | -44.9% | 400,060 | -55.4% | 5.82% | -14.7% |
| SNY | Sell | SANOFIsponsored adr | $27,097,311 | -41.3% | 559,515 | -53.9% | 5.82% | -9.3% |
| JNJ | Sell | JOHNSON & JOHNSON | $19,401,646 | -45.1% | 109,831 | -49.2% | 4.16% | -15.0% |
| SNDX | Sell | SYNDAX PHARMACEUTICALS INC | $18,083,777 | -8.5% | 710,561 | -13.6% | 3.88% | +41.4% |
| MRK | Sell | MERCK & CO INC | $13,380,570 | -57.7% | 120,600 | -67.1% | 2.87% | -34.5% |
| ABBV | Sell | ABBVIE INC | $9,696,600 | -55.5% | 60,000 | -63.0% | 2.08% | -31.2% |
| NVO | Sell | NOVO-NORDISK A Sadr | $9,682,224 | -67.2% | 71,540 | -75.9% | 2.08% | -49.3% |
| LLY | Sell | LILLY ELI & CO | $9,398,430 | -79.8% | 25,690 | -82.1% | 2.02% | -68.7% |
| KROS | Sell | KEROS THERAPEUTICS INC | $7,623,511 | -2.0% | 158,757 | -23.2% | 1.64% | +51.5% |
| Sell | ARCELLX INC | $7,357,378 | +17.3% | 237,488 | -28.9% | 1.58% | +81.5% | |
| PNT | Sell | POINT BIOPHARMA GLOBAL INC | $6,944,760 | -14.7% | 952,642 | -9.5% | 1.49% | +31.9% |
| KURA | Sell | KURA ONCOLOGY INC | $6,928,342 | -35.8% | 558,287 | -29.3% | 1.49% | -0.7% |
| IMTX | Sell | IMMATICS N.V | $6,801,221 | -14.5% | 780,852 | -1.8% | 1.46% | +32.2% |
| ALT | Sell | ALTIMMUNE INC | $6,255,902 | -18.4% | 380,298 | -36.6% | 1.34% | +26.2% |
| ISEE | Sell | IVERIC BIO INC | $4,187,603 | -59.9% | 195,591 | -66.4% | 0.90% | -38.0% |
| KDNY | Sell | CHINOOK THERAPEUTICS INC | $3,332,640 | -68.3% | 127,200 | -76.2% | 0.72% | -51.0% |
| ETNB | Sell | 89BIO INC | $2,299,038 | -39.7% | 180,600 | -72.6% | 0.49% | -6.8% |
| BIIB | Sell | BIOGEN INC | $2,081,331 | -86.0% | 7,516 | -86.5% | 0.45% | -78.3% |
| MGIC | Sell | MAGIC SOFTWARE ENTERPRISES Lord | $352,199 | -72.2% | 21,981 | -73.0% | 0.08% | -56.8% |
| U | Exit | UNITY SOFTWARE INC | $0 | – | -11,500 | -100.0% | -0.05% | – |
| Exit | WIX COM LTDnote 8/1 | $0 | – | -700,000 | -100.0% | -0.08% | – | |
| EWTX | Exit | EDGEWISE THERAPEUTICS INC | $0 | – | -60,000 | -100.0% | -0.08% | – |
| NICE | Exit | NICE LTDsponsored adr | $0 | – | -3,145 | -100.0% | -0.08% | – |
| ICL | Exit | ICL GROUP LTD | $0 | – | -111,482 | -100.0% | -0.13% | – |
| MDWD | Exit | MEDIWOUND LTD | $0 | – | -688,716 | -100.0% | -0.13% | – |
| PSTX | Exit | POSEIDA THERAPEUTICS INC | $0 | – | -300,000 | -100.0% | -0.15% | – |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -120,000 | -100.0% | -0.17% | – |
| Exit | ALTIMMUNE INCput | $0 | – | -100,000 | -100.0% | -0.18% | – | |
| RUN | Exit | SUNRUN INC | $0 | – | -65,000 | -100.0% | -0.25% | – |
| Exit | DICE THERAPEUTICS INCput | $0 | – | -150,000 | -100.0% | -0.42% | – | |
| Exit | DICE THERAPEUTICS INC | $0 | – | -152,913 | -100.0% | -0.43% | – | |
| Exit | RELMADA THERAPEUTICS INCput | $0 | – | -93,000 | -100.0% | -0.48% | – | |
| Exit | SENTINELONE INCcall | $0 | – | -164,800 | -100.0% | -0.58% | – | |
| NVDA | Exit | NVIDIA CORPORATION | $0 | – | -40,000 | -100.0% | -0.67% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDsponsored ads | $0 | – | -776,346 | -100.0% | -0.87% | – |
| Exit | GENERAC HLDGS INCcall | $0 | – | -35,600 | -100.0% | -0.88% | – | |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -105,090 | -100.0% | -0.90% | – |
| SEDG | Exit | SOLAREDGE TECHNOLOGIES INC | $0 | – | -29,426 | -100.0% | -0.94% | – |
| RLMD | Exit | RELMADA THERAPEUTICS INC | $0 | – | -193,230 | -100.0% | -0.99% | – |
| S | Exit | SENTINELONE INCcl a | $0 | – | -280,000 | -100.0% | -0.99% | – |
| Exit | PERION NETWORK LTD | $0 | – | -405,184 | -100.0% | -1.08% | – | |
| ADBE | Exit | ADOBE SYSTEMS INCORPORATED | $0 | – | -29,150 | -100.0% | -1.11% | – |
| GLBE | Exit | GLOBAL E ONLINE LTD | $0 | – | -311,460 | -100.0% | -1.16% | – |
| KRNT | Exit | KORNIT DIGITAL LTD | $0 | – | -322,926 | -100.0% | -1.19% | – |
| WIX | Exit | WIX COM LTD | $0 | – | -129,000 | -100.0% | -1.40% | – |
| PANW | Exit | PALO ALTO NETWORKS INC | $0 | – | -63,000 | -100.0% | -1.43% | – |
| Exit | UNITY SOFTWARE INCcall | $0 | – | -367,500 | -100.0% | -1.62% | – | |
| Exit | NVIDIA CORPORATIONcall | $0 | – | -172,600 | -100.0% | -2.91% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.