$910 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 90 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 100.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| LOGC | Exit | LOGICBIO THERAPEUTICS INC | $0 | – | -24,042 | -100.0% | -0.01% | – |
| IMCR | Exit | IMMUNOCORE HLDGS PLCads | $0 | – | -4,235 | -100.0% | -0.01% | – |
| SRSA | Exit | SARISSA CAPITAL ACQUISITN COcl a | $0 | – | -23,900 | -100.0% | -0.02% | – |
| UPWK | Exit | UPWORK INC | $0 | – | -10,000 | -100.0% | -0.04% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -22,000 | -100.0% | -0.06% | – |
| CMLTU | Exit | CM LIFE SCIENCES III INCunit 04/30/2028 | $0 | – | -75,000 | -100.0% | -0.06% | – |
| YMTX | Exit | YUMANITY THERAPEUTICS INC | $0 | – | -75,836 | -100.0% | -0.07% | – |
| ACIU | Exit | AC IMMUNE SA | $0 | – | -121,019 | -100.0% | -0.07% | – |
| OMEG | Exit | OMEGA ALPHA SPACcl a | $0 | – | -100,000 | -100.0% | -0.08% | – |
| FLAC | Exit | FRAZIER LIFESCIENCES ACQU CO | $0 | – | -126,687 | -100.0% | -0.10% | – |
| Exit | ERASCA INC | $0 | – | -70,000 | -100.0% | -0.12% | – | |
| MOLN | Exit | MOLECULAR PARTNERS AGads | $0 | – | -80,555 | -100.0% | -0.13% | – |
| AMAT | Exit | APPLIED MATLS INC | $0 | – | -14,500 | -100.0% | -0.16% | – |
| ACHL | Exit | ACHILLES THERAPEUTICS PLCsponsored ads | $0 | – | -242,500 | -100.0% | -0.16% | – |
| JYAC | Exit | JIYA ACQUISITION CORP | $0 | – | -199,028 | -100.0% | -0.16% | – |
| TMPM | Exit | TURMERIC ACQUISITION CORPcl a | $0 | – | -219,440 | -100.0% | -0.18% | – |
| CVRX | Exit | CVRX INC | $0 | – | -150,000 | -100.0% | -0.21% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -100,391 | -100.0% | -0.22% | – |
| Exit | HIPPO HLDGS INC | $0 | – | -564,967 | -100.0% | -0.22% | – | |
| GLUE | Exit | MONTE ROSA THERAPEUTICS INC | $0 | – | -119,647 | -100.0% | -0.22% | – |
| Exit | DICE THERAPEUTICS INC | $0 | – | -85,000 | -100.0% | -0.23% | – | |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -23,647 | -100.0% | -0.27% | – |
| EUCR | Exit | EUCRATES BIOMEDICAL ACQU COR | $0 | – | -329,025 | -100.0% | -0.27% | – |
| DVAX | Exit | DYNAVAX TECHNOLOGIES CORP | $0 | – | -198,880 | -100.0% | -0.32% | – |
| ALGS | Exit | ALIGOS THERAPEUTICS INC | $0 | – | -249,197 | -100.0% | -0.32% | – |
| IS | Exit | IRONSOURCE LTD | $0 | – | -367,070 | -100.0% | -0.34% | – |
| PTGX | Exit | PROTAGONIST THERAPEUTICS INC | $0 | – | -260,379 | -100.0% | -0.39% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -491,159 | -100.0% | -0.39% | – |
| Exit | CARIBOU BIOSCIENCES INC | $0 | – | -200,000 | -100.0% | -0.40% | – | |
| CALX | Exit | CALIX INC | $0 | – | -105,290 | -100.0% | -0.44% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -172,000 | -100.0% | -0.46% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -373,510 | -100.0% | -0.48% | – |
| RACB | Exit | RESEARCH ALLIANCE CORP II | $0 | – | -600,000 | -100.0% | -0.50% | – |
| ZEN | Exit | ZENDESK INC | $0 | – | -53,910 | -100.0% | -0.53% | – |
| AFMD | Exit | AFFIMED N V | $0 | – | -1,117,619 | -100.0% | -0.58% | – |
| ADSK | Exit | AUTODESK INC | $0 | – | -27,500 | -100.0% | -0.66% | – |
| RUN | Exit | SUNRUN INC | $0 | – | -189,000 | -100.0% | -0.70% | – |
| NKE | Exit | NIKE INCcl b | $0 | – | -65,000 | -100.0% | -0.79% | – |
| ALXO | Exit | ALX ONCOLOGY HLDGS INC | $0 | – | -128,706 | -100.0% | -0.80% | – |
| TEVA | Exit | TEVA PHARMACEUTICAL INDS LTDcall | $0 | – | -1,050,000 | -100.0% | -0.86% | – |
| AUDC | Exit | AUDIOCODES LTDord | $0 | – | -316,428 | -100.0% | -0.86% | – |
| KRNT | Exit | KORNIT DIGITAL LTD | $0 | – | -72,076 | -100.0% | -0.88% | – |
| NICE | Exit | NICE LTDsponsored adr | $0 | – | -37,786 | -100.0% | -0.90% | – |
| ALT | Exit | ALTIMMUNE INCcall | $0 | – | -1,000,000 | -100.0% | -0.95% | – |
| TWLO | Exit | TWILIO INCcl a | $0 | – | -35,500 | -100.0% | -0.95% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INCcall | $0 | – | -350,000 | -100.0% | -0.99% | – |
| SEDG | Exit | SOLAREDGE TECHNOLOGIES INC | $0 | – | -50,000 | -100.0% | -1.11% | – |
| BIIB | Exit | BIOGEN INCcall | $0 | – | -50,000 | -100.0% | -1.19% | – |
| BMY | Exit | BRISTOL-MYERS SQUIBB COcall | $0 | – | -500,000 | -100.0% | -2.49% | – |
| IWM | Exit | ISHARES TRput | $0 | – | -210,000 | -100.0% | -3.86% | – |
| XBI | Exit | SPDR SER TRput | $0 | – | -400,000 | -100.0% | -4.22% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.