$725 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 110 reported holdings in Q2 2018. The portfolio turnover from Q1 2018 to Q2 2018 was 57.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SHPG | Sell | SHIRE PLCsponsored adr | $21,353,000 | -27.3% | 126,500 | -35.6% | 2.94% | -33.9% |
| SRPT | Sell | SAREPTA THERAPEUTICS INC | $19,179,000 | +4.0% | 145,096 | -41.7% | 2.64% | -5.6% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $18,573,000 | -33.1% | 1,189,056 | -35.6% | 2.56% | -39.2% |
| BIIB | Sell | BIOGEN INC | $14,512,000 | -18.5% | 50,000 | -23.1% | 2.00% | -25.9% |
| PFE | Sell | PFIZER INC | $14,149,000 | -32.4% | 390,000 | -33.9% | 1.95% | -38.6% |
| ARQL | Sell | ARQULE INC | $8,282,000 | +27.0% | 1,497,683 | -33.9% | 1.14% | +15.4% |
| VKTX | Sell | VIKING THERAPEUTICS INC | $7,425,000 | +6.7% | 782,424 | -50.9% | 1.02% | -3.1% |
| IMMU | Sell | IMMUNOMEDICS INC | $7,259,000 | +3.5% | 306,655 | -36.1% | 1.00% | -6.0% |
| MLNX | Sell | MELLANOX TECHNOLOGIES LTD | $7,246,000 | -0.8% | 85,954 | -14.3% | 1.00% | -9.9% |
| ALDX | Sell | ALDEYRA THERAPEUTICS INC | $6,733,000 | -11.0% | 846,935 | -16.1% | 0.93% | -19.2% |
| NICE | Sell | NICE LTDsponsored adr | $6,231,000 | -2.1% | 60,043 | -11.4% | 0.86% | -11.1% |
| ARRY | Sell | ARRAY BIOPHARMA INC | $5,702,000 | -13.7% | 339,804 | -16.1% | 0.79% | -21.7% |
| ADMS | Sell | ADAMAS PHARMACEUTICALS INC | $5,518,000 | -31.2% | 213,625 | -36.3% | 0.76% | -37.5% |
| ASND | Sell | ASCENDIS PHARMA A Ssponsored adr | $5,192,000 | -16.8% | 78,048 | -18.3% | 0.72% | -24.5% |
| RETA | Sell | REATA PHARMACEUTICALS INCcl a | $4,757,000 | +3.1% | 136,044 | -39.5% | 0.66% | -6.4% |
| GOOGL | Sell | ALPHABET INCcap stk cl a | $3,691,000 | -25.7% | 3,269 | -31.8% | 0.51% | -32.6% |
| OBSV | Sell | OBSEVA SA | $3,689,000 | -63.3% | 243,669 | -67.3% | 0.51% | -66.6% |
| FLEX | Sell | FLEX LTDord | $3,666,000 | -27.1% | 259,824 | -15.6% | 0.50% | -33.8% |
| PRQR | Sell | PROQR THRAPEUTICS N V | $3,604,000 | +78.0% | 493,749 | -25.0% | 0.50% | +61.9% |
| ABEO | Sell | ABEONA THERAPEUTICS INC | $3,571,000 | -15.6% | 223,172 | -24.3% | 0.49% | -23.5% |
| ALNA | Sell | ALLENA PHARMACEUTICALS INC | $3,484,000 | -22.9% | 267,349 | -34.8% | 0.48% | -30.0% |
| CTMX | Sell | CYTOMX THERAPEUTICS INC | $1,901,000 | -62.9% | 83,142 | -53.8% | 0.26% | -66.3% |
| DK | Sell | DELEK US HLDGS INC NEW | $1,231,000 | -75.3% | 24,533 | -79.9% | 0.17% | -77.5% |
| RDCM | Sell | RADCOM LTD | $1,042,000 | -13.7% | 52,760 | -19.8% | 0.14% | -21.3% |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $677,000 | -88.1% | 34,475 | -88.6% | 0.09% | -89.2% |
| RDWR | Sell | RADWARE LTDord | $443,000 | +13.9% | 17,527 | -3.9% | 0.06% | +3.4% |
| CHTR | Sell | CHARTER COMMUNICATIONS INC Ncl a | $416,000 | -59.8% | 1,419 | -57.4% | 0.06% | -63.7% |
| LPSN | Exit | LIVEPERSON INC | $0 | – | -136 | -100.0% | 0.00% | – |
| ATHX | Exit | ATHERSYS INC | $0 | – | -773 | -100.0% | 0.00% | – |
| VSTO | Exit | VISTA OUTDOOR INC | $0 | – | -6,000 | -100.0% | -0.02% | – |
| XRAY | Exit | DENTSPLY SIRONA INC | $0 | – | -2,500 | -100.0% | -0.02% | – |
| GLIBA | Exit | GCI LIBERTY INC | $0 | – | -3,000 | -100.0% | -0.02% | – |
| SEE | Exit | SEALED AIR CORP NEW | $0 | – | -4,500 | -100.0% | -0.03% | – |
| CMCSA | Exit | COMCAST CORP NEWcl a | $0 | – | -10,000 | -100.0% | -0.05% | – |
| WSO | Exit | WATSCO INC | $0 | – | -2,100 | -100.0% | -0.06% | – |
| VTVT | Exit | VTV THERAPEUTICS INCcl a | $0 | – | -281,679 | -100.0% | -0.17% | – |
| PRGO | Exit | PERRIGO CO PLC | $0 | – | -19,221 | -100.0% | -0.24% | – |
| FGEN | Exit | FIBROGEN INC | $0 | – | -39,779 | -100.0% | -0.28% | – |
| EXPE | Exit | EXPEDIA GROUP INC | $0 | – | -18,900 | -100.0% | -0.32% | – |
| VBIV | Exit | VBI VACCINES INC | $0 | – | -666,284 | -100.0% | -0.35% | – |
| ERYP | Exit | ERYTECH PHARMAsponsored adr | $0 | – | -120,000 | -100.0% | -0.38% | – |
| ASNS | Exit | ARSANIS INC | $0 | – | -114,972 | -100.0% | -0.40% | – |
| BOLD | Exit | AUDENTES THERAPEUTICS INC | $0 | – | -95,000 | -100.0% | -0.43% | – |
| CHRS | Exit | COHERUS BIOSCIENCES INC | $0 | – | -270,000 | -100.0% | -0.45% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -100,000 | -100.0% | -0.45% | – |
| CMTA | Exit | CLEMENTIA PHARMACEUTICALS IN | $0 | – | -200,000 | -100.0% | -0.46% | – |
| GEMP | Exit | GEMPHIRE THERAPEUTICS INC | $0 | – | -481,046 | -100.0% | -0.48% | – |
| ENDP | Exit | ENDO INTL PLC | $0 | – | -550,000 | -100.0% | -0.50% | – |
| NTLA | Exit | INTELLIA THERAPEUTICS INC | $0 | – | -160,000 | -100.0% | -0.51% | – |
| MGNX | Exit | MACROGENICS INC | $0 | – | -135,000 | -100.0% | -0.52% | – |
| REPH | Exit | RECRO PHARMA INC | $0 | – | -364,197 | -100.0% | -0.61% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -60,000 | -100.0% | -0.62% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -298,472 | -100.0% | -0.64% | – |
| EIGR | Exit | EIGER BIOPHARMACEUTICALS INC | $0 | – | -475,000 | -100.0% | -0.71% | – |
| TSRO | Exit | TESARO INC | $0 | – | -106,175 | -100.0% | -0.92% | – |
| MNOV | Exit | MEDICINOVA INC | $0 | – | -630,838 | -100.0% | -0.98% | – |
| PTLA | Exit | PORTOLA PHARMACEUTICALS INCcall | $0 | – | -200,000 | -100.0% | -0.99% | – |
| LJPC | Exit | LA JOLLA PHARMACEUTICAL CO | $0 | – | -260,000 | -100.0% | -1.18% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -168,000 | -100.0% | -1.35% | – |
| QQQ | Exit | POWERSHARES QQQ TRUSTput | $0 | – | -80,000 | -100.0% | -1.94% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -41,500 | -100.0% | -2.17% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -319,000 | -100.0% | -4.32% | – |
| XBI | Exit | SPDR SERIES TRUSTput | $0 | – | -750,000 | -100.0% | -9.99% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2018-08-13
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.