$614 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 107 reported holdings in Q3 2016. The portfolio turnover from Q2 2016 to Q3 2016 was 76.9% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | SPDR SERIES TRUSTput | $106,064,000 | – | 1,600,000 | +100.0% | 17.27% | – | |
| New | ISHARES TRput | $57,892,000 | – | 200,000 | +100.0% | 9.43% | – | |
| MRK | Buy | MERCK & CO INC | $18,723,000 | +225.0% | 300,000 | +200.0% | 3.05% | +103.7% |
| TEVA | Sell | TEVA PHARMACEUTICAL INDS LTDadr | $18,496,000 | -38.6% | 402,000 | -33.0% | 3.01% | -61.5% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $16,154,000 | – | 263,047 | +100.0% | 2.63% | – |
| AGN | Sell | ALLERGAN PLC | $16,122,000 | -26.6% | 70,000 | -26.3% | 2.62% | -53.9% |
| LLY | LILLY ELI & CO | $16,052,000 | +1.9% | 200,000 | 0.0% | 2.61% | -36.1% | |
| BIIB | Sell | BIOGEN INC | $15,652,000 | +28.2% | 50,000 | -1.0% | 2.55% | -19.6% |
| CLCD | Sell | COLUCID PHARMACEUTICALS INC | $15,260,000 | +273.5% | 400,000 | -20.0% | 2.48% | +134.2% |
| PFE | PFIZER INC | $14,449,000 | -3.8% | 426,612 | 0.0% | 2.35% | -39.7% | |
| ITRN | Sell | ITURAN LOCATION AND CONTROL | $12,083,000 | +15.6% | 456,668 | -0.8% | 1.97% | -27.5% |
| CELG | Sell | CELGENE CORP | $11,498,000 | -24.8% | 110,000 | -29.0% | 1.87% | -52.8% |
| AMGN | New | AMGEN INC | $10,993,000 | – | 65,900 | +100.0% | 1.79% | – |
| HZNP | Buy | HORIZON PHARMA PLC | $9,700,000 | +1078.6% | 535,000 | +970.0% | 1.58% | +637.9% |
| GILD | Sell | GILEAD SCIENCES INC | $8,917,000 | -44.5% | 112,700 | -41.5% | 1.45% | -65.2% |
| ALXN | New | ALEXION PHARMACEUTICALS INC | $8,578,000 | – | 70,000 | +100.0% | 1.40% | – |
| MYL | Sell | MYLAN N V | $7,624,000 | -29.5% | 200,000 | -20.0% | 1.24% | -55.8% |
| New | BIOMARIN PHARMACEUTICAL INCcall | $7,402,000 | – | 80,000 | +100.0% | 1.20% | – | |
| SAGE | Buy | SAGE THERAPEUTICS INC | $7,345,000 | +250.8% | 159,500 | +129.5% | 1.20% | +119.9% |
| FOLD | Sell | AMICUS THERAPEUTICS INC | $6,697,000 | +22.1% | 905,000 | -10.0% | 1.09% | -23.5% |
| AZN | New | ASTRAZENECA PLCsponsored adr | $6,572,000 | – | 200,000 | +100.0% | 1.07% | – |
| AKAOQ | New | ACHAOGEN INC | $6,228,000 | – | 1,300,313 | +100.0% | 1.01% | – |
| ARRY | New | ARRAY BIOPHARMA INC | $6,075,000 | – | 900,000 | +100.0% | 0.99% | – |
| NICE | New | NICE LTDsponsored adr | $5,760,000 | – | 86,040 | +100.0% | 0.94% | – |
| CRVS | CORVUS PHARMACEUTICALS INC | $5,347,000 | +16.8% | 325,053 | 0.0% | 0.87% | -26.7% | |
| ASND | Buy | ASCENDIS PHARMA A Ssponsored adr | $5,296,000 | +52.4% | 263,500 | +0.6% | 0.86% | -4.4% |
| GLYC | GLYCOMIMETICS INC | $5,134,000 | -1.6% | 718,080 | 0.0% | 0.84% | -38.3% | |
| TSRO | New | TESARO INC | $5,012,000 | – | 50,000 | +100.0% | 0.82% | – |
| EIGR | Buy | EIGER BIOPHARMACEUTICALS INC | $5,002,000 | +67.5% | 373,568 | +147.9% | 0.81% | +4.9% |
| Sell | NEURODERM LTD | $4,687,000 | +11.6% | 253,513 | -1.9% | 0.76% | -30.1% | |
| ADMS | ADAMAS PHARMACEUTICALS INC | $4,431,000 | +8.4% | 270,000 | 0.0% | 0.72% | -32.0% | |
| CHTR | Buy | CHARTER COMMUNICATIONS INC Ncl a | $4,364,000 | +18.8% | 16,165 | +0.6% | 0.71% | -25.5% |
| RTRX | Buy | RETROPHIN INC | $4,252,000 | +59.1% | 190,000 | +26.7% | 0.69% | -0.3% |
| AVXS | New | AVEXIS INC | $4,121,000 | – | 100,000 | +100.0% | 0.67% | – |
| GWPH | Sell | GW PHARMACEUTICALS PLCads | $4,115,000 | +12.3% | 31,000 | -22.5% | 0.67% | -29.5% |
| SELB | New | SELECTA BIOSCIENCES INC | $3,989,000 | – | 284,652 | +100.0% | 0.65% | – |
| ACAD | New | ACADIA PHARMACEUTICALS INC | $3,976,000 | – | 125,000 | +100.0% | 0.65% | – |
| CLSD | Sell | CLEARSIDE BIOMEDICAL INC | $3,923,000 | +86.5% | 226,100 | -24.6% | 0.64% | +17.0% |
| MGNX | MACROGENICS INC | $3,888,000 | +10.8% | 130,000 | 0.0% | 0.63% | -30.5% | |
| GOOGL | Buy | ALPHABET INCcap stk cl a | $3,874,000 | +32.3% | 4,818 | +15.8% | 0.63% | -17.0% |
| ITEK | Buy | INOTEK PHARMACEUTICALS CORP | $3,809,000 | +104.8% | 401,764 | +60.7% | 0.62% | +28.4% |
| FIS | New | FIDELITY NATL INFORMATION SV | $3,710,000 | – | 48,160 | +100.0% | 0.60% | – |
| ALDR | New | ALDER BIOPHARMACEUTICALS INC | $3,687,000 | – | 112,500 | +100.0% | 0.60% | – |
| UNP | New | UNION PAC CORP | $3,635,000 | – | 37,275 | +100.0% | 0.59% | – |
| V | Buy | VISA INC | $3,539,000 | +25.7% | 42,791 | +12.7% | 0.58% | -21.2% |
| ORBK | Buy | ORBOTECH LTDord | $3,438,000 | +59.8% | 116,102 | +37.9% | 0.56% | +0.2% |
| FOMX | FOAMIX PHARMACEUTICALS LTD | $3,167,000 | +45.8% | 342,000 | 0.0% | 0.52% | -8.5% | |
| APD | New | AIR PRODS & CHEMS INC | $3,164,000 | – | 21,045 | +100.0% | 0.52% | – |
| FPRX | FIVE PRIME THERAPEUTICS INC | $3,149,000 | +26.9% | 60,000 | 0.0% | 0.51% | -20.3% | |
| GNCA | Sell | GENOCEA BIOSCIENCES INC | $3,119,000 | +7.3% | 609,271 | -14.1% | 0.51% | -32.7% |
| Buy | GILEAD SCIENCES INCcall | $3,102,000 | -25.6% | 39,200 | +7740.0% | 0.50% | -53.4% | |
| ACOR | Buy | ACORDA THERAPEUTICS INC | $3,090,000 | +23.6% | 148,000 | +51.0% | 0.50% | -22.5% |
| ENDP | ENDO INTL PLC | $3,023,000 | +29.2% | 150,000 | 0.0% | 0.49% | -18.9% | |
| FGEN | Buy | FIBROGEN INC | $3,016,000 | +114.5% | 145,700 | +70.0% | 0.49% | +34.5% |
| ALDX | ALDEYRA THERAPEUTICS INC | $2,893,000 | +38.0% | 368,500 | 0.0% | 0.47% | -13.4% | |
| DBVT | Buy | DBV TECHNOLOGIES S Asponsored adr | $2,872,000 | +45.3% | 79,058 | +30.4% | 0.47% | -8.8% |
| KITE | KITE PHARMA INC | $2,793,000 | +11.7% | 50,000 | 0.0% | 0.46% | -29.9% | |
| New | APPLE INCcall | $2,759,000 | – | 18,500 | +100.0% | 0.45% | – | |
| SNA | New | SNAP ON INC | $2,755,000 | – | 18,130 | +100.0% | 0.45% | – |
| BOLD | New | AUDENTES THERAPEUTICS INC | $2,672,000 | – | 150,000 | +100.0% | 0.44% | – |
| FWP | FORWARD PHARMA A/Ssponsored adr | $2,552,000 | +15.6% | 121,500 | 0.0% | 0.42% | -27.4% | |
| Buy | ISHARES TRput | $2,546,000 | +1173.0% | 20,500 | +925.0% | 0.42% | +698.1% | |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $2,521,000 | – | 166,310 | +100.0% | 0.41% | – |
| MDGN | MEDGENICS INC | $2,507,000 | +0.4% | 450,000 | 0.0% | 0.41% | -37.1% | |
| VSAR | New | VERSARTIS INC | $2,450,000 | – | 200,000 | +100.0% | 0.40% | – |
| MRNS | Buy | MARINUS PHARMACEUTICALS INC | $2,440,000 | +64.1% | 1,340,588 | +14.5% | 0.40% | +2.8% |
| CATB | Buy | CATABASIS PHARMACEUTICALS IN | $2,390,000 | +217.8% | 387,943 | +90.9% | 0.39% | +99.5% |
| DERM | DERMIRA INC | $2,367,000 | +15.6% | 70,000 | 0.0% | 0.38% | -27.6% | |
| VTGN | Buy | VISTAGEN THERAPEUTICS INC | $2,263,000 | +97.3% | 544,100 | +85.0% | 0.37% | +23.5% |
| SBUX | New | STARBUCKS CORP | $2,252,000 | – | 41,600 | +100.0% | 0.37% | – |
| EGLTQ | EGALET CORP | $2,226,000 | +53.4% | 292,500 | 0.0% | 0.36% | -4.0% | |
| AAP | Sell | ADVANCE AUTO PARTS INC | $2,173,000 | -51.4% | 14,569 | -47.3% | 0.35% | -69.5% |
| ADXS | New | ADVAXIS INC | $2,138,000 | – | 200,000 | +100.0% | 0.35% | – |
| ARDX | New | ARDELYX INC | $1,964,000 | – | 151,813 | +100.0% | 0.32% | – |
| TRILLIUM THERAPEUTICS INC | $1,955,000 | +64.6% | 132,300 | 0.0% | 0.32% | +3.2% | ||
| XENE | New | XENON PHARMACEUTICALS INC | $1,847,000 | – | 228,029 | +100.0% | 0.30% | – |
| PRTK | PARATEK PHARMACEUTICALS INC | $1,821,000 | -6.5% | 140,000 | 0.0% | 0.30% | -41.4% | |
| SMMT | SUMMIT THERAPEUTICS PLCspons ads | $1,813,000 | +16.1% | 197,450 | 0.0% | 0.30% | -27.3% | |
| RPRX | New | REPROS THERAPEUTICS INC | $1,805,000 | – | 863,807 | +100.0% | 0.29% | – |
| ADRO | Sell | ADURO BIOTECH INC | $1,740,000 | -9.5% | 140,000 | -17.6% | 0.28% | -43.3% |
| NVLS | New | NIVALIS THERAPEUTICS INC | $1,664,000 | – | 204,700 | +100.0% | 0.27% | – |
| KERX | Sell | KERYX BIOPHARMACEUTICALS INC | $1,655,000 | -55.6% | 311,600 | -44.6% | 0.27% | -72.2% |
| EDGE | EDGE THERAPEUTICS INC | $1,562,000 | +3.0% | 150,000 | 0.0% | 0.25% | -35.5% | |
| IMDZ | Buy | IMMUNE DESIGN CORP | $1,539,000 | +23.3% | 203,000 | +32.7% | 0.25% | -22.5% |
| BURL | New | BURLINGTON STORES INC | $1,499,000 | – | 18,500 | +100.0% | 0.24% | – |
| PIRS | PIERIS PHARMACEUTICALS INC | $1,482,000 | +13.7% | 810,000 | 0.0% | 0.24% | -28.9% | |
| SHPG | Sell | SHIRE PLCsponsored adr | $1,454,000 | -93.3% | 7,500 | -97.2% | 0.24% | -95.8% |
| VTVT | New | VTV THERAPEUTICS INCcl a | $1,438,000 | – | 200,000 | +100.0% | 0.23% | – |
| MYOK | New | MYOKARDIA INC | $1,360,000 | – | 83,240 | +100.0% | 0.22% | – |
| ACIU | New | AC IMMUNE SA | $1,314,000 | – | 79,800 | +100.0% | 0.21% | – |
| IMMU | IMMUNOMEDICS INC | $1,300,000 | +40.1% | 400,000 | 0.0% | 0.21% | -12.0% | |
| PTN | Buy | PALATIN TECHNOLOGIES INC | $1,199,000 | +167.6% | 1,906,037 | +87.7% | 0.20% | +68.1% |
| PANW | New | PALO ALTO NETWORKS INC | $1,124,000 | – | 7,052 | +100.0% | 0.18% | – |
| ABUS | ARBUTUS BIOPHARMA CORP | $1,032,000 | -1.1% | 300,000 | 0.0% | 0.17% | -38.0% | |
| SPNS | Buy | SAPIENS INTL CORP N V | $1,032,000 | +44.5% | 80,844 | +32.6% | 0.17% | -9.2% |
| MRTX | MIRATI THERAPEUTICS INC | $992,000 | +21.1% | 150,000 | 0.0% | 0.16% | -23.9% | |
| ONS | Sell | ONCOBIOLOGICS INC | $850,000 | -3.5% | 200,000 | -22.8% | 0.14% | -39.7% |
| ARWR | New | ARROWHEAD PHARMACEUTICALS IN | $735,000 | – | 100,000 | +100.0% | 0.12% | – |
| ORA | New | ORMAT TECHNOLOGIES INC | $370,000 | – | 7,640 | +100.0% | 0.06% | – |
| ALIM | New | ALIMERA SCIENCES INC | $299,000 | – | 200,715 | +100.0% | 0.05% | – |
| SITE | New | SITEONE LANDSCAPE SUPPLY INC | $288,000 | – | 8,020 | +100.0% | 0.05% | – |
| UNH | New | UNITEDHEALTH GROUP INC | $238,000 | – | 1,700 | +100.0% | 0.04% | – |
| MHK | New | MOHAWK INDS INC | $220,000 | – | 1,100 | +100.0% | 0.04% | – |
| CABO | New | CABLE ONE INC | $216,000 | – | 370 | +100.0% | 0.04% | – |
| LOW | New | LOWES COS INC | $212,000 | – | 2,940 | +100.0% | 0.04% | – |
| HSIC | New | SCHEIN HENRY INC | $163,000 | – | 1,000 | +100.0% | 0.03% | – |
| ELLO | ELLOMAY CAPITAL LIMITED | $51,000 | +18.6% | 5,653 | 0.0% | 0.01% | -27.3% | |
| INSYQ | Exit | INSYS THERAPEUTICS INC NEW | $0 | – | -16,407 | -100.0% | -0.06% | – |
| SCYX | Exit | SCYNEXIS INC | $0 | – | -128,500 | -100.0% | -0.07% | – |
| CYTK | Exit | CYTOKINETICS INC | $0 | – | -32,069 | -100.0% | -0.08% | – |
| ABEO | Exit | ABEONA THERAPEUTICS INC | $0 | – | -138,105 | -100.0% | -0.08% | – |
| CERU | Exit | CERULEAN PHARMA INC | $0 | – | -450,000 | -100.0% | -0.25% | – |
| SERV | Exit | SERVICEMASTER GLOBAL HLDGS I | $0 | – | -27,750 | -100.0% | -0.29% | – |
| PTCT | Exit | PTC THERAPEUTICS INC | $0 | – | -174,461 | -100.0% | -0.32% | – |
| VRX | Exit | VALEANT PHARMACEUTICALS INTL | $0 | – | -68,500 | -100.0% | -0.36% | – |
| BLUE | Exit | BLUEBIRD BIO INC | $0 | – | -40,000 | -100.0% | -0.45% | – |
| CYNA | Exit | CYNAPSUS THERAPEUTICS INC | $0 | – | -134,037 | -100.0% | -0.58% | – |
| RLYP | Exit | RELYPSA INC | $0 | – | -130,000 | -100.0% | -0.62% | – |
| CLVS | Exit | CLOVIS ONCOLOGY INC | $0 | – | -200,000 | -100.0% | -0.71% | – |
| Exit | ALDER BIOPHARMACEUTICALS INC | $0 | – | -112,500 | -100.0% | -0.73% | – | |
| Exit | GW PHARMACEUTICALS PLCcall | $0 | – | -310 | -100.0% | -0.74% | – | |
| Exit | SAGE THERAPEUTICS INCcall | $0 | – | -1,000 | -100.0% | -0.78% | – | |
| RDUS | Exit | RADIUS HEALTH INC | $0 | – | -90,000 | -100.0% | -0.86% | – |
| Exit | ALNYLAM PHARMACEUTICALS INCput | $0 | – | -600 | -100.0% | -0.86% | – | |
| BCOMF | Exit | B COMMUNICATIONS LTD | $0 | – | -148,861 | -100.0% | -0.92% | – |
| Exit | TESARO INCcall | $0 | – | -450 | -100.0% | -0.98% | – | |
| Exit | ACHAOGEN INC | $0 | – | -1,257,366 | -100.0% | -1.24% | – | |
| Exit | ACADIA HEALTHCARE COMPANY INcall | $0 | – | -1,500 | -100.0% | -1.26% | – | |
| Exit | ALEXION PHARMACEUTICALS INC | $0 | – | -42,323 | -100.0% | -1.28% | – | |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -57,600 | -100.0% | -1.29% | – |
| RARE | Exit | ULTRAGENYX PHARMACEUTICAL IN | $0 | – | -105,000 | -100.0% | -1.33% | – |
| Exit | BIOGEN INCput | $0 | – | -250 | -100.0% | -1.57% | – | |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -398,287 | -100.0% | -1.66% | – |
| Exit | AMGEN INC | $0 | – | -85,000 | -100.0% | -3.36% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2016-11-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
| SC 13G | 2023-08-30 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.