$438 Million is the total value of SPHERA FUNDS MANAGEMENT LTD.'s 114 reported holdings in Q1 2014. The portfolio turnover from Q4 2013 to Q1 2014 was 211.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| NVS | Buy | Novartis AGsponsored adr | $45,435,000 | +1784.5% | 535,100 | +1683.7% | 10.37% | +1443.5% |
| GSK | Buy | GlaxoSmithKline PLCsponsored adr | $34,730,000 | +18.3% | 650,000 | +18.2% | 7.93% | -3.1% |
| SNY | New | Sanofisponsored adr | $33,378,000 | – | 320,000 | +100.0% | 7.62% | – |
| MRK | Buy | Merck & Co Inc | $30,088,000 | +114.7% | 530,000 | +89.3% | 6.87% | +75.9% |
| PFE | Buy | Pfizer Inc | $27,450,000 | +27.6% | 854,596 | +21.7% | 6.27% | +4.6% |
| JNJ | Buy | Johnson & Johnson | $21,964,000 | +2976.2% | 223,600 | +2766.7% | 5.01% | +2419.6% |
| LLY | New | Eli Lilly & Co | $17,658,000 | – | 300,000 | +100.0% | 4.03% | – |
| XLV | Buy | HEALTH CARE SELECT SECTOR HEDGEFUNDsbi healthcare | $9,321,000 | +23.6% | 159,353 | +17.2% | 2.13% | +1.3% |
| SGEN | Buy | Seattle Genetics Inc | $5,823,000 | +18.9% | 127,800 | +4.1% | 1.33% | -2.6% |
| PRGO | New | PERRIGO CO | $5,584,000 | – | 36,106 | +100.0% | 1.28% | – |
| BIIB | Buy | Biogen Idec Inc | $5,200,000 | +54.9% | 17,000 | +41.7% | 1.19% | +27.0% |
| UTHR | New | United Therapeutics Corp | $4,702,000 | – | 50,000 | +100.0% | 1.07% | – |
| TJX | Buy | TJX COMPANIES INC | $4,544,000 | +9.3% | 74,916 | +14.9% | 1.04% | -10.4% |
| CL | Buy | COLGATE-PALMOLIVE CO | $4,074,000 | +17.2% | 62,799 | +17.8% | 0.93% | -3.9% |
| NKE | Buy | NIKE INC -CL Bcl b | $3,659,000 | +210.3% | 49,544 | +230.4% | 0.84% | +154.6% |
| New | SPDR S&P Biotech ETFput | $3,620,000 | – | 2,800 | +100.0% | 0.83% | – | |
| XLE | New | ENERGY SELECT SECTOR SPDR HEDGEFUNDsbi int-energy | $3,562,000 | – | 40,000 | +100.0% | 0.81% | – |
| BRCM | Buy | BROADCOM CORP-CL Acl a | $3,542,000 | +24.5% | 112,500 | +17.2% | 0.81% | +2.0% |
| FEZ | New | SPDR EURO STOXX 50 ETF HEDGEFUNDeuro stoxx 50 | $3,541,000 | – | 83,000 | +100.0% | 0.81% | – |
| ORBK | Buy | ORBOTECH LTDord | $3,435,000 | +22.9% | 223,174 | +7.9% | 0.78% | +0.6% |
| WAG | Buy | WALGREEN CO | $3,397,000 | +67.5% | 51,453 | +45.8% | 0.78% | +37.2% |
| CSX | Buy | CSX CORP | $3,384,000 | +60.4% | 116,825 | +59.3% | 0.77% | +31.5% |
| GOOGL | New | GOOGLE INC-CL Acl a | $3,192,000 | – | 2,864 | +100.0% | 0.73% | – |
| PCP | Buy | PRECISION CASTPARTS CORP | $3,165,000 | +11.7% | 12,520 | +19.0% | 0.72% | -8.4% |
| CVS | New | CVS CAREMARK CORP | $2,680,000 | – | 35,795 | +100.0% | 0.61% | – |
| PCLN | Buy | PRICELINE.COM INC | $2,672,000 | +16.4% | 2,242 | +13.5% | 0.61% | -4.7% |
| RGDO | New | Regado Biosciences Inc | $2,504,000 | – | 200,000 | +100.0% | 0.57% | – |
| RDHL | New | Redhill Biopharma Ltdsponsored ads | $2,428,000 | – | 1,714,880 | +100.0% | 0.55% | – |
| AQXP | New | Aquinox Pharmaceuticals Inc | $2,419,000 | – | 190,000 | +100.0% | 0.55% | – |
| New | BioMarin Pharmaceutical Incnote 1.875% 4/2 | $2,387,000 | – | 35,000 | +100.0% | 0.54% | – | |
| AERI | Buy | Aerie Pharmaceuticals Inc | $2,384,000 | +20.6% | 112,500 | +2.3% | 0.54% | -1.1% |
| LVS | Buy | LAS VEGAS SANDS CORP | $2,249,000 | +15.6% | 27,847 | +12.8% | 0.51% | -5.4% |
| RNN | Buy | Rexahn Pharmaceuticals Inc | $2,167,000 | +183.3% | 2,006,200 | +33.7% | 0.50% | +132.4% |
| PRTA | Buy | Prothena Corp PLC | $2,107,000 | +58.9% | 55,000 | +10.0% | 0.48% | +30.4% |
| NVMI | New | NOVA MEASURING INSTRUMENTS US | $2,029,000 | – | 181,184 | +100.0% | 0.46% | – |
| TRVN | New | Trevena Inc | $1,965,000 | – | 250,000 | +100.0% | 0.45% | – |
| GLMD | New | Galmed Pharmaceuticals Ltd | $1,950,000 | – | 170,000 | +100.0% | 0.44% | – |
| ITCI | New | Intra-Cellular Therapies Inc | $1,818,000 | – | 100,000 | +100.0% | 0.42% | – |
| FPRX | New | FivePrime Therapeutics Inc | $1,769,000 | – | 90,000 | +100.0% | 0.40% | – |
| SMMF | New | Summit Corp PLC | $1,753,000 | – | 10,921,656 | +100.0% | 0.40% | – |
| NCR | New | NCR CORPORATION | $1,749,000 | – | 47,840 | +100.0% | 0.40% | – |
| GLYC | New | GlycoMimetics Inc | $1,731,000 | – | 106,000 | +100.0% | 0.40% | – |
| FLXN | New | Flexion Therapeutics Inc | $1,710,000 | – | 103,955 | +100.0% | 0.39% | – |
| RXDX | New | Ignyta Inc | $1,702,000 | – | 205,000 | +100.0% | 0.39% | – |
| New | Medivation Incnote 2.625% 4/0 | $1,609,000 | – | 25,000 | +100.0% | 0.37% | – | |
| QURE | New | uniQure B.V. | $1,555,000 | – | 100,000 | +100.0% | 0.36% | – |
| GNVC | New | GenVec Inc | $1,524,000 | – | 575,000 | +100.0% | 0.35% | – |
| AMPE | New | Ampio Pharmaceuticals Inc | $1,429,000 | – | 225,000 | +100.0% | 0.33% | – |
| CYTR | Buy | CytRx Corp | $1,413,000 | -27.3% | 405,000 | +30.6% | 0.32% | -40.3% |
| VRTX | New | Vertex Pharmaceuticals Inc | $1,414,000 | – | 20,000 | +100.0% | 0.32% | – |
| RLYP | Buy | Relypsa Inc | $1,410,000 | +88.0% | 47,300 | +57.7% | 0.32% | +54.1% |
| TGTX | New | TG Therapeutics Inc | $1,380,000 | – | 200,000 | +100.0% | 0.32% | – |
| CTIC | New | Cell Therapeutics Inc | $1,360,000 | – | 400,000 | +100.0% | 0.31% | – |
| BLRX | New | BioLine RX Ltdsponsored adr | $1,338,000 | – | 600,000 | +100.0% | 0.30% | – |
| INSM | Buy | Insmed Inc | $1,333,000 | +66.8% | 70,000 | +48.9% | 0.30% | +36.3% |
| OCRX | Buy | Ocera Therapeutics Inc | $1,278,000 | +562.2% | 121,148 | +714.1% | 0.29% | +440.7% |
| TLOG | Buy | TetraLogic Pharmaceuticals Cor | $1,276,000 | -23.4% | 200,000 | +14.3% | 0.29% | -37.3% |
| IMMU | New | Immunomedics Inc | $1,263,000 | – | 300,000 | +100.0% | 0.29% | – |
| DPRX | New | Dipexium Pharmaceuticals Inc | $1,255,000 | – | 125,000 | +100.0% | 0.29% | – |
| ADS | New | ALLIANCE DATA SYSTEMS CORP | $1,252,000 | – | 4,596 | +100.0% | 0.29% | – |
| CRIS | New | Curis Inc | $1,237,000 | – | 438,800 | +100.0% | 0.28% | – |
| GALTW | New | Galectin Therapeutics Inc*w exp 03/28/201 | $1,225,000 | – | 80,000 | +100.0% | 0.28% | – |
| PPHM | New | Peregrine Pharmaceuticals Inc | $1,216,000 | – | 640,000 | +100.0% | 0.28% | – |
| NKTR | New | Nektar Therapeutics | $1,212,000 | – | 100,000 | +100.0% | 0.28% | – |
| OMER | New | Omeros Corp | $1,207,000 | – | 100,000 | +100.0% | 0.28% | – |
| New | Gilead Sciences Inccall | $1,140,000 | – | 2,000 | +100.0% | 0.26% | – | |
| MGNX | New | MacroGenics Inc | $1,141,000 | – | 41,000 | +100.0% | 0.26% | – |
| TNXP | New | Tonix Pharmaceuticals Holding | $1,041,000 | – | 100,000 | +100.0% | 0.24% | – |
| ELLO | Buy | ELLOMAY CAPITAL LTD | $995,000 | +4.2% | 100,853 | +1.9% | 0.23% | -14.7% |
| New | GlaxoSmithKline PLCcall | $878,000 | – | 3,000 | +100.0% | 0.20% | – | |
| BIOD | New | Biodel Inc | $775,000 | – | 283,900 | +100.0% | 0.18% | – |
| New | COMPUGEN LTDord | $726,000 | – | 69,109 | +100.0% | 0.17% | – | |
| ORA | New | ORMAT TECHNOLOGIES INC | $704,000 | – | 23,472 | +100.0% | 0.16% | – |
| New | Ishares Russell 2000 Indexput | $690,000 | – | 3,000 | +100.0% | 0.16% | – | |
| FFIV | New | F5 NETWORKS INC | $663,000 | – | 6,222 | +100.0% | 0.15% | – |
| New | Vertex Pharmaceuticals Inccall | $543,000 | – | 500 | +100.0% | 0.12% | – | |
| IMGN | New | Immunogen Inc | $515,000 | – | 34,500 | +100.0% | 0.12% | – |
| CSTE | New | CAESARSTONE SDOT-YAM LTD | $426,000 | – | 7,830 | +100.0% | 0.10% | – |
| VICL | New | Vical Inc | $387,000 | – | 300,000 | +100.0% | 0.09% | – |
| New | Insmed Inccall | $355,000 | – | 1,000 | +100.0% | 0.08% | – | |
| New | Impax Laboratories Inccall | $335,000 | – | 1,000 | +100.0% | 0.08% | – | |
| New | Auxilium Pharmaceuticals Inccall | $332,000 | – | 935 | +100.0% | 0.08% | – | |
| New | Corcept Therapeutics Inccall | $124,000 | – | 1,206 | +100.0% | 0.03% | – | |
| New | Cytokinetics Inccall | $16,000 | – | 131 | +100.0% | 0.00% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2014-05-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| TEVA PHARMACEUTICAL-SP ADR | 36 | Q3 2023 | 8.4% |
| MERCK & CO INC NEW | 35 | Q3 2023 | 8.4% |
| NICE Systems Ltd | 27 | Q3 2023 | 4.4% |
| BIOGEN INC | 26 | Q3 2023 | 6.7% |
| AMICUS THERAPEUTICS INC | 26 | Q2 2022 | 4.3% |
| PFIZER INC | 25 | Q3 2023 | 9.2% |
| SAREPTA THERAPEUTICS INC | 25 | Q3 2023 | 3.2% |
| JOHNSON & JOHNSON | 24 | Q3 2023 | 8.0% |
| UNIQURE NV | 23 | Q3 2023 | 1.2% |
| SYNDAX PHARMACEUTICALS INC | 22 | Q3 2023 | 3.9% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Cyclacel Pharmaceuticals, Inc. | February 06, 2023 | 250,000 | 2.0% |
| Altimmune, Inc. | February 14, 2022 | 1,244,241 | 3.1% |
| Allot Ltd. | February 16, 2021 | 1,129,054 | 3.2% |
| Larimar Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Neos Therapeutics, Inc. | February 16, 2021 | ? | ? |
| Orgenesis Inc. | February 16, 2021 | 525,216 | 0.0% |
| Sio Gene Therapies Inc. | February 16, 2021 | ? | ? |
| X4 Pharmaceuticals, Inc | February 16, 2021 | 250,000 | 0.0% |
| Axovant Gene Therapies Ltd. | February 25, 2020 | 2,931,017 | 8.0% |
| Axovant Gene Therapies Ltd. | February 11, 2020 | 398,540 | 1.8% |
View SPHERA FUNDS MANAGEMENT LTD.'s complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2024-05-15 |
| 13F-HR/A | 2024-02-15 |
| 13F-HR | 2024-02-14 |
| SC 13G | 2024-02-08 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| SC 13G/A | 2024-02-05 |
| 13F-HR | 2023-11-14 |
| SC 13G | 2023-10-10 |
View SPHERA FUNDS MANAGEMENT LTD.'s complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.