RTW INVESTMENTS, LP - Q3 2023 holdings

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$4.74 Billion is the total value of RTW INVESTMENTS, LP's 67 reported holdings in Q3 2023. The portfolio turnover from Q2 2023 to Q3 2023 was 24.2% .

All
New
Buy
Sell
Exit
Unchanged
 Value Shares↓ Weighting
RCKT  ROCKET PHARMACEUTICALS INC$362,422,448
+3.1%
17,687,7720.0%7.65%
+14.3%
IMCR BuyIMMUNOCORE HLDGS PLCads$316,402,485
-12.5%
6,096,387
+1.1%
6.68%
-3.0%
AXSM BuyAXSOME THERAPEUTICS INC$313,777,864
+1.9%
4,489,596
+4.8%
6.62%
+13.0%
ALNY  ALNYLAM PHARMACEUTICALS INC$298,123,410
-6.8%
1,683,3620.0%6.29%
+3.3%
MRTX BuyMIRATI THERAPEUTICS INC$294,836,470
+82.4%
6,768,514
+51.3%
6.22%
+102.2%
ARGX BuyARGENX SEsponsored adr$249,352,278
+32.7%
507,195
+5.2%
5.26%
+47.0%
ACAD BuyACADIA PHARMACEUTICALS INC$241,255,031
+3.0%
11,576,537
+18.3%
5.09%
+14.1%
BRKR BuyBRUKER CORP$210,680,097
-3.7%
3,381,703
+14.3%
4.44%
+6.7%
RARE  ULTRAGENYX PHARMACEUTICAL IN$192,691,423
-22.7%
5,405,0890.0%4.07%
-14.3%
PEN  PENUMBRA INC$162,895,179
-29.7%
673,3710.0%3.44%
-22.1%
PTCT  PTC THERAPEUTICS INC$162,140,742
-44.9%
7,235,1960.0%3.42%
-38.9%
TMO  THERMO FISHER SCIENTIFIC INC$146,958,361
-3.0%
290,3340.0%3.10%
+7.5%
MASI  MASIMO CORP$131,650,906
-46.7%
1,501,4930.0%2.78%
-40.9%
ESTA  ESTABLISHMENT LABS HLDGS INC$122,387,352
-28.5%
2,494,1380.0%2.58%
-20.7%
NTRA BuyNATERA INC$117,341,398
-7.7%
2,651,783
+1.5%
2.48%
+2.4%
VCEL  VERICEL CORP$110,343,583
-10.8%
3,291,8730.0%2.33%
-1.1%
SAGE NewSAGE THERAPEUTICS INC$105,976,340–5,149,482
+100.0%
2.24%–
CLDX  CELLDEX THERAPEUTICS INC NEW$95,307,292
-18.9%
3,463,2010.0%2.01%
-10.1%
PTGX  PROTAGONIST THERAPEUTICS INC$90,330,774
-39.6%
5,415,5140.0%1.91%
-33.1%
CYTK  CYTOKINETICS INC$75,835,873
-9.7%
2,574,1980.0%1.60%
+0.1%
AVDL BuyAVADEL PHARMACEUTICALS PLCsponsored adr$73,505,075
-34.5%
7,136,415
+4.8%
1.55%
-27.4%
TXG Buy10X GENOMICS INC$62,698,185
-23.3%
1,519,956
+3.9%
1.32%
-14.9%
TSHA NewTAYSHA GENE THERAPIES INC$53,382,465–16,893,185
+100.0%
1.13%–
TARS BuyTARSUS PHARMACEUTICALS INC$51,190,057
+11.2%
2,880,701
+13.1%
1.08%
+23.1%
 ORCHESTRA BIOMED HLDGS INC$49,011,981
+24.6%
5,620,6400.0%1.03%
+38.1%
INSM BuyINSMED INC$47,093,977
+123.2%
1,865,108
+86.5%
0.99%
+147.3%
MRUS BuyMERUS N V$47,083,695
+70.2%
1,996,764
+90.0%
0.99%
+88.4%
NewAPOGEE THERAPEUTICS INC$45,637,188–2,142,591
+100.0%
0.96%–
MDGL BuyMADRIGAL PHARMACEUTICALS INC$45,197,189
-11.7%
309,485
+39.7%
0.95%
-2.1%
RNA  AVIDITY BIOSCIENCES INC$42,680,854
-42.5%
6,689,7890.0%0.90%
-36.2%
GHRS BuyGH RESEARCH PLCordinary shares$33,437,646
+29.9%
3,327,129
+53.4%
0.70%
+43.9%
 MOONLAKE IMMUNOTHERAPEUTICSclass a ord$28,500,000
+11.8%
500,0000.0%0.60%
+23.9%
ILMN SellILLUMINA INC$25,825,800
-63.4%
188,125
-50.0%
0.54%
-59.4%
FULC SellFULCRUM THERAPEUTICS INC$25,835,490
+29.1%
5,818,804
-4.0%
0.54%
+43.0%
ALKS NewALKERMES PLC$24,902,935–889,073
+100.0%
0.52%–
AXNX SellAXONICS INC$24,832,370
-44.4%
442,487
-50.0%
0.52%
-38.4%
SWAV NewSHOCKWAVE MED INC$24,688,400–124,000
+100.0%
0.52%–
SCPH  SCPHARMACEUTICALS INC$23,480,642
-30.1%
3,297,8430.0%0.50%
-22.7%
 ROIVANT SCIENCES LTD$18,135,735
+15.9%
1,552,7170.0%0.38%
+28.5%
STOK  STOKE THERAPEUTICS INC$17,298,799
-62.9%
4,390,5580.0%0.36%
-58.9%
NewALLURION TECHNOLOGIES INC$14,868,140–3,457,707
+100.0%
0.31%–
GH  GUARDANT HEALTH INC$14,846,291
-17.2%
500,8870.0%0.31%
-8.2%
PMVP SellPMV PHARMACEUTICALS INC$14,587,320
-23.1%
2,375,785
-21.6%
0.31%
-14.7%
URGN  UROGEN PHARMA LTD$12,013,071
+35.4%
857,4640.0%0.25%
+49.7%
CUTR  CUTERA INC$11,116,508
-60.2%
1,846,5960.0%0.24%
-55.8%
MIST  MILESTONE PHARMACEUTICALS IN$10,093,916
+8.8%
3,256,1020.0%0.21%
+20.3%
 ACELYRIN INC$9,949,413
-51.3%
978,3100.0%0.21%
-46.0%
IMTX  IMMATICS N.V$9,785,100
+0.3%
845,0000.0%0.21%
+10.8%
OM  OUTSET MED INC$8,798,199
-50.3%
808,6580.0%0.19%
-44.8%
 MINERALYS THERAPEUTICS INC$8,769,171
-44.2%
922,1000.0%0.18%
-38.1%
SYK NewSTRYKER CORPORATION$7,651,560–28,000
+100.0%
0.16%–
RLMD  RELMADA THERAPEUTICS INC$6,395,505
+22.0%
2,131,8350.0%0.14%
+35.0%
IMUX BuyIMMUNIC INC$6,372,825
-40.9%
4,335,255
+0.9%
0.13%
-34.6%
DSGN BuyDESIGN THERAPEUTICS INC$5,930,647
-39.8%
2,512,986
+60.8%
0.12%
-33.2%
ACET  ADICET BIO INC$5,810,817
-43.6%
4,241,4720.0%0.12%
-37.2%
APYX  APYX MEDICAL CORPORATION$5,687,021
-36.4%
1,777,1940.0%0.12%
-29.4%
 DERMTECH INC$3,914,433
-44.6%
2,718,3560.0%0.08%
-38.5%
XGN  EXAGEN INC$3,611,685
-16.6%
1,492,4320.0%0.08%
-7.3%
NewSAGIMET BIOSCIENCES INC$3,522,438–400,277
+100.0%
0.07%–
VKTX SellVIKING THERAPEUTICS INC$2,871,558
-82.3%
259,400
-74.1%
0.06%
-80.3%
OLK SellOLINK HLDG ABsponsored ads$2,413,867
-80.3%
163,652
-75.0%
0.05%
-78.2%
AKYA  AKOYA BIOSCIENCES INC$1,573,662
-37.1%
338,4220.0%0.03%
-31.2%
ARYD  ARYA SCIENCES ACQU CORP IVcl a$1,384,635
+2.8%
127,9700.0%0.03%
+11.5%
NewRAYZEBIO INC$1,027,860–46,300
+100.0%
0.02%–
NewSIENTRA INC$845,220–304,036
+100.0%
0.02%–
MIRO  MIROMATRIX MED INC$583,241
-25.1%
445,2220.0%0.01%
-20.0%
 ROCKET PHARMACEUTICALS INC*w exp 09/02/202$59,500
-10.5%
350,0000.0%0.00%0.0%
MRSN ExitMERSANA THERAPEUTICS INC$0–-614,838
-100.0%
-0.04%–
BDTX ExitBLACK DIAMOND THERAPEUTICS I$0–-1,700,000
-100.0%
-0.16%–
MRVI ExitMARAVAI LIFESCIENCES HLDGS I$0–-1,532,685
-100.0%
-0.36%–
ISRG ExitINTUITIVE SURGICAL INC$0–-170,000
-100.0%
-1.11%–
HZNP ExitHORIZON THERAPEUTICS PUB L$0–-1,000,000
-100.0%
-1.96%–
Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR filed 2023-11-14
Signatures

The EDGAR filing(s) were signed by:

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
ALNYLAM PHARMACEUTICALS INC36Q3 202319.7%
MASIMO CORP32Q3 20235.8%
LA JOLLA PHARMACEUTICAL CO31Q2 20229.7%
REGENXBIO INC30Q4 202210.8%
AGENUS INC29Q2 20229.0%
PTC THERAPEUTICS INC28Q3 202312.8%
DICERNA PHARMACEUTICALS INC28Q3 202110.8%
MIRATI THERAPEUTICS INC26Q3 20236.2%
ARGENX SE26Q3 20235.3%
VERICEL CORP24Q3 20233.9%

View RTW INVESTMENTS, LP's complete holdings history.

Latest significant ownerships (13-D/G)
RTW INVESTMENTS, LP Q3 2023 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
ROCKET PHARMACEUTICALS, INC.September 19, 202318,188,457-
ALLURION TECHNOLOGIES, INC.August 11, 20233,457,7077.4%
Orchestra BioMed Holdings, Inc.May 05, 20235,620,64515.7%
Renovacor, Inc.Sold outApril 05, 20230-
Adverum Biotechnologies, Inc.Sold outFebruary 14, 202300.0%
Aptevo Therapeutics Inc.Sold outFebruary 14, 202300.0%
ASLAN Pharmaceuticals LtdSold outFebruary 14, 202300.0%
Athira Pharma, Inc.Sold outFebruary 14, 202300.0%
BELLUS Health Inc.Sold outFebruary 14, 202300.0%
Clearside Biomedical, Inc.Sold outFebruary 14, 202300.0%

View RTW INVESTMENTS, LP's complete significant-ownership history.

Latest filings
TypeFiled
SC 13D/A2024-04-17
SC 13D/A2024-03-01
13F-HR2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14
SC 13G/A2024-02-14

View RTW INVESTMENTS, LP's complete filings history.

All filings

View complete filings history.

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