$2.65 Billion is the total value of RTW INVESTMENTS, LP's 61 reported holdings in Q4 2019. The portfolio turnover from Q3 2019 to Q4 2019 was 41.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RCKT | Buy | Rocket Pharmaceuticals Inc | $382,652,000 | +98.8% | 16,812,491 | +1.4% | 14.44% | +26.1% |
| ALNY | Sell | Alnylam Pharmaceuticals Inc | $188,633,000 | +32.7% | 1,637,864 | -7.3% | 7.12% | -15.8% |
| PTCT | Buy | PTC Therapeutics Inc | $184,074,000 | +49.1% | 3,832,480 | +5.0% | 6.94% | -5.4% |
| DRNA | Sell | Dicerna Pharmaceuticals Inc | $129,409,000 | +45.3% | 5,874,229 | -5.3% | 4.88% | -7.8% |
| AXSM | Buy | Axsome Therapeutics Inc | $106,131,000 | +519.7% | 1,026,813 | +21.4% | 4.00% | +293.3% |
| BMY | Buy | Bristol Myers Squibb Co | $105,461,000 | +32.9% | 1,642,951 | +5.0% | 3.98% | -15.7% |
| STOK | Buy | Stoke Therapeutics Inc | $100,373,000 | +44.6% | 3,544,248 | +5.6% | 3.79% | -8.2% |
| FIXX | Buy | Homology Medicines Inc | $90,029,000 | +103.1% | 4,349,250 | +77.6% | 3.40% | +28.8% |
| MRTX | Buy | Mirati Therapeutics Inc | $83,170,000 | +80.1% | 645,427 | +8.9% | 3.14% | +14.3% |
| SRPT | Sell | Sarepta Therapeutics Inc | $78,168,000 | +43.3% | 605,762 | -16.4% | 2.95% | -9.1% |
| ADVM | Buy | Adverum Biotechnologies Inc | $73,574,000 | +114.9% | 6,386,607 | +1.7% | 2.78% | +36.3% |
| IMVT | New | Immunovant Inc | $66,048,000 | – | 4,426,106 | +100.0% | 2.49% | – |
| ZBH | Buy | Zimmer Biomet Holdings Inc | $65,468,000 | +18.3% | 437,385 | +8.5% | 2.47% | -24.9% |
| MIST | Buy | Milestone Pharmaceuticals In | $63,372,000 | -0.7% | 3,958,264 | +12.4% | 2.39% | -37.0% |
| MASI | Buy | Masimo Corp | $60,408,000 | +9.4% | 382,187 | +3.0% | 2.28% | -30.6% |
| ESTA | Sell | Establishment Labs Hldgs Inc | $56,217,000 | +45.8% | 2,032,446 | -0.4% | 2.12% | -7.5% |
| MYOK | Buy | Myokardia Inc | $55,465,000 | +46.7% | 760,988 | +5.0% | 2.09% | -6.9% |
| VCEL | Buy | Vericel Corp | $52,016,000 | +29.9% | 2,989,429 | +13.0% | 1.96% | -17.6% |
| PRQR | Buy | ProQR Thrapeutics N V | $47,361,000 | +122.2% | 4,779,135 | +29.1% | 1.79% | +40.9% |
| AXNX | Buy | Axonics Modulation Tech Inc | $44,104,000 | +6.8% | 1,591,632 | +3.7% | 1.66% | -32.3% |
| ACHN | Sell | Achillion Pharmaceuticals In | $44,076,000 | -11.7% | 7,309,383 | -47.3% | 1.66% | -44.0% |
| BLU | Buy | Bellus Health Inc New | $36,566,000 | +36.2% | 4,840,992 | +15.9% | 1.38% | -13.6% |
| AGEN | Sell | Agenus Inc | $36,127,000 | +52.0% | 8,876,391 | -3.7% | 1.36% | -3.6% |
| APYX | Buy | Apyx Med Corp | $28,690,000 | +25.7% | 3,391,279 | +0.6% | 1.08% | -20.3% |
| DermTech Inc | $28,413,000 | +127.3% | 2,386,871 | 0.0% | 1.07% | +44.3% | ||
| ARVN | Sell | Arvinas Inc | $27,542,000 | +57.9% | 670,295 | -17.2% | 1.04% | +0.1% |
| TBIO | Buy | Translate Bio Inc | $26,901,000 | -13.8% | 3,304,808 | +5.0% | 1.02% | -45.3% |
| RLMD | New | Relmada Therapeutics Inc | $25,915,000 | – | 664,484 | +100.0% | 0.98% | – |
| AVDL | New | Avadel Pharmaceuticals plcsponsored adr | $25,681,000 | – | 3,401,434 | +100.0% | 0.97% | – |
| FREQ | New | Frequency Therapeutics Inc | $21,762,000 | – | 1,302,862 | +100.0% | 0.82% | – |
| CSTL | Sell | Castle Biosciences Inc | $21,690,000 | +60.9% | 631,072 | -15.3% | 0.82% | +2.0% |
| MDXG | Sell | MiMedx Group Inc | $20,485,000 | +41.0% | 2,702,539 | -8.8% | 0.77% | -10.5% |
| XGN | Buy | Exagen Inc | $18,261,000 | +130.4% | 718,946 | +40.5% | 0.69% | +46.3% |
| PTGX | Buy | Protagonist Therapeutics Inc | $17,343,000 | +89.4% | 2,459,988 | +222.7% | 0.65% | +20.2% |
| JNJ | Johnson & Johnson | $17,046,000 | +12.7% | 116,858 | 0.0% | 0.64% | -28.5% | |
| NSTG | New | NanoString Technologies Inc | $16,106,000 | – | 578,932 | +100.0% | 0.61% | – |
| ABUS | Buy | Arbutus Biopharma Corp | $15,754,000 | +85.7% | 5,666,754 | +1.9% | 0.59% | +17.6% |
| TELA | New | Tela Bio Inc | $14,755,000 | – | 1,139,358 | +100.0% | 0.56% | – |
| WVE | New | WAVE Life Sciences Ltd | $13,669,000 | – | 1,705,474 | +100.0% | 0.52% | – |
| NTRA | Buy | Natera Inc | $13,575,000 | +44.0% | 402,953 | +40.2% | 0.51% | -8.7% |
| A | New | Agilent Technologies Inc | $12,770,000 | – | 149,690 | +100.0% | 0.48% | – |
| RGNX | Buy | Regenxbio Inc | $12,521,000 | +20.8% | 305,611 | +5.0% | 0.47% | -23.4% |
| PODD | Sell | Insulet Corp | $11,595,000 | -36.8% | 67,725 | -39.1% | 0.44% | -59.9% |
| ODT | Buy | Odonate Therapeutics Inc | $11,577,000 | +30.9% | 356,752 | +5.0% | 0.44% | -16.9% |
| QURE | Buy | Uniqure NV | $10,899,000 | +91.1% | 152,096 | +5.0% | 0.41% | +21.2% |
| CLSD | Buy | Clearside Biomedical Inc | $10,875,000 | +360.6% | 3,750,107 | +0.1% | 0.41% | +192.9% |
| STAA | New | STAAR Surgical Co | $10,629,000 | – | 302,211 | +100.0% | 0.40% | – |
| INMD | Inmode Ltd | $9,800,000 | +82.2% | 250,000 | 0.0% | 0.37% | +15.6% | |
| TMDX | Transmedics Group Inc | $9,567,000 | -20.0% | 503,266 | 0.0% | 0.36% | -49.2% | |
| BWAY | Buy | Brainsway Ltdsponsored ads | $9,345,000 | +22.9% | 958,426 | +14.8% | 0.35% | -21.9% |
| LJPC | Buy | La Jolla Pharmaceutical Co | $8,992,000 | -49.3% | 2,287,991 | +13.5% | 0.34% | -67.9% |
| CTMX | Buy | Cytomx Therapeutics Inc | $8,639,000 | +18.2% | 1,039,593 | +5.0% | 0.33% | -25.1% |
| PHGE | New | Biomx Inc | $5,811,000 | – | 600,000 | +100.0% | 0.22% | – |
| ARGX | Buy | argenx SEsponsored adr | $5,097,000 | +41.9% | 31,752 | +0.7% | 0.19% | -10.3% |
| Vivus Inc 4.5 05/01/2020note 4.500% 5/0 | $2,918,000 | -0.1% | 4,000,000 | 0.0% | 0.11% | -36.8% | ||
| PSNL | Personalis Inc | $2,780,000 | -25.7% | 255,000 | 0.0% | 0.10% | -52.9% | |
| MOTS | Buy | Motus Gi Hldgs Inc | $1,776,000 | +32.7% | 775,640 | +14.8% | 0.07% | -16.2% |
| FLGT | New | Fulgent Genetics Inc | $968,000 | – | 75,000 | +100.0% | 0.04% | – |
| VRAY | New | Viewray Inc | $633,000 | – | 150,000 | +100.0% | 0.02% | – |
| TXG | 10x Genomics Inc | $381,000 | +51.2% | 5,000 | 0.0% | 0.01% | -6.7% | |
| PHGEWS | New | BIOMX Inc*w exp 10/16/202 | $288,000 | – | 600,000 | +100.0% | 0.01% | – |
| LVGO | Exit | Livongo Health Inc | $0 | – | -15,000 | -100.0% | -0.02% | – |
| OPTN | Exit | Optinose Inc | $0 | – | -87,805 | -100.0% | -0.04% | – |
| STIM | Exit | Neuronetics Inc | $0 | – | -167,728 | -100.0% | -0.08% | – |
| SLDB | Exit | Solid Biosciences Inc | $0 | – | -145,541 | -100.0% | -0.09% | – |
| CDNA | Exit | CareDx Inc | $0 | – | -154,951 | -100.0% | -0.21% | – |
| SNSS | Exit | Sunesis Pharmaceuticals Inc | $0 | – | -6,946,074 | -100.0% | -0.30% | – |
| CHACU | Exit | Chardan Healthcare Acquisitiunit 12/13/2023 | $0 | – | -600,000 | -100.0% | -0.43% | – |
| PRNB | Exit | Principia Biopharma Inc | $0 | – | -270,948 | -100.0% | -0.46% | – |
| SILK | Exit | Silk Road Medical Inc | $0 | – | -244,716 | -100.0% | -0.47% | – |
| FLDM | Exit | Fluidigm Corp Del | $0 | – | -2,109,500 | -100.0% | -0.58% | – |
| QTNT | Exit | Quotient Ltd | $0 | – | -1,281,143 | -100.0% | -0.59% | – |
| QDEL | Exit | Quidel Corp | $0 | – | -176,495 | -100.0% | -0.64% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.