$1.07 Billion is the total value of RTW INVESTMENTS, LP's 47 reported holdings in Q4 2018. The portfolio turnover from Q3 2018 to Q4 2018 was 58.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| RCKT | Buy | Rocket Pharmaceuticals Inc | $235,848,000 | -36.0% | 16,037,486 | +7.1% | 21.95% | -0.5% |
| ARWR | Sell | ARROWHEAD PHARMACEUTICALS IN | $66,027,000 | -54.7% | 5,316,156 | -30.1% | 6.15% | -29.6% |
| PTCT | Sell | PTC Therapeutics Inc | $65,975,000 | -57.1% | 1,922,346 | -41.3% | 6.14% | -33.4% |
| DRNA | Buy | Dicerna Pharmaceuticals Inc | $63,147,000 | -24.2% | 5,907,088 | +8.2% | 5.88% | +17.8% |
| BMY | Buy | BRISTOL MYERS SQUIBB CO | $49,422,000 | -15.9% | 950,780 | +0.4% | 4.60% | +30.7% |
| RGNX | Sell | Regenxbio Inc | $44,058,000 | -60.0% | 1,050,245 | -28.0% | 4.10% | -37.8% |
| LIVN | LivaNova PLC | $40,525,000 | -26.2% | 443,036 | 0.0% | 3.77% | +14.7% | |
| SRPT | Buy | Sarepta Therapeutics Inc | $39,932,000 | -21.3% | 365,911 | +16.5% | 3.72% | +22.4% |
| VCEL | Buy | Vericel Corp | $39,831,000 | +26.9% | 2,289,134 | +3.2% | 3.71% | +97.3% |
| MASI | Buy | Masimo Corp | $36,744,000 | -5.0% | 342,221 | +10.2% | 3.42% | +47.7% |
| FIXX | Buy | Homology Medicines Inc | $36,525,000 | +267.4% | 1,633,491 | +275.6% | 3.40% | +471.4% |
| ALNY | Buy | Alnylam Pharmaceuticals Inc | $32,044,000 | -5.9% | 439,498 | +13.0% | 2.98% | +46.3% |
| AGEN | Buy | Agenus Inc | $24,122,000 | +14.7% | 10,135,119 | +3.2% | 2.24% | +78.3% |
| ESTA | Buy | ESTABLISHMENT LABS HLDGS INC | $22,740,000 | +25.7% | 848,058 | +9.3% | 2.12% | +95.5% |
| ACHN | Buy | ACHILLION PHARMACEUTICALS IN | $21,862,000 | -56.3% | 13,749,383 | +1.1% | 2.04% | -32.1% |
| ADVM | Buy | Adverum Biotechnologies Inc | $19,709,000 | +1662.9% | 6,256,840 | +3285.4% | 1.83% | +2637.3% |
| SIBN | New | SI BONE INC | $16,802,000 | – | 804,327 | +100.0% | 1.56% | – |
| ABUS | Buy | Arbutus Biopharma Corp | $16,606,000 | -57.0% | 4,335,746 | +6.1% | 1.55% | -33.1% |
| AXNX | New | AXONICS MODULATION TECH INC | $16,551,000 | – | 1,095,396 | +100.0% | 1.54% | – |
| SAGE | New | SAGE Therapeutics Inc | $15,900,000 | – | 165,990 | +100.0% | 1.48% | – |
| ASMB | New | Assembly Biosciences Inc | $15,532,000 | – | 686,644 | +100.0% | 1.45% | – |
| MYOK | Buy | Myokardia Inc | $14,409,000 | -19.3% | 294,898 | +7.7% | 1.34% | +25.4% |
| PRNB | Sell | Principia Biopharma Inc | $14,162,000 | -18.5% | 555,948 | -13.7% | 1.32% | +26.7% |
| CTMX | New | Cytomx Therapeutics Inc | $13,720,000 | – | 908,586 | +100.0% | 1.28% | – |
| QURE | Buy | Uniqure NV | $13,310,000 | -14.7% | 461,837 | +7.7% | 1.24% | +32.5% |
| JNJ | New | Johnson & Johnson | $10,399,000 | – | 80,583 | +100.0% | 0.97% | – |
| CNCE | New | Concert Pharmaceuticals Inc | $9,900,000 | – | 788,877 | +100.0% | 0.92% | – |
| VRAY | Sell | Viewray Inc | $8,280,000 | -73.9% | 1,364,156 | -59.8% | 0.77% | -59.4% |
| CDNA | Sell | CareDx Inc | $8,238,000 | -20.2% | 327,703 | -8.4% | 0.77% | +24.1% |
| KIDS | New | Orthopediatrics Corp | $7,848,000 | – | 225,000 | +100.0% | 0.73% | – |
| FLDM | New | FLUIDIGM CORP DEL | $7,622,000 | – | 884,235 | +100.0% | 0.71% | – |
| PRQR | Sell | PROQR THRAPEUTICS N V | $7,072,000 | -90.2% | 448,141 | -88.0% | 0.66% | -84.8% |
| CHACU | New | CHARDAN HEALTHCARE ACQUISITIunit 12/13/2023 | $6,042,000 | – | 600,000 | +100.0% | 0.56% | – |
| VIVE | Buy | VIVEVE MED INC | $4,705,000 | -44.2% | 4,480,565 | +42.4% | 0.44% | -13.3% |
| ODT | Buy | Odonate Therapeutics Inc | $4,390,000 | -21.9% | 311,790 | +7.7% | 0.41% | +21.4% |
| SLDB | Sell | Solid Biosciences Inc | $3,578,000 | -71.1% | 133,506 | -49.1% | 0.33% | -55.1% |
| ECOR | Buy | ELECTROCORE INC | $3,243,000 | -54.9% | 518,010 | +0.7% | 0.30% | -29.9% |
| STIM | Buy | Neuronetics Inc | $3,246,000 | -35.7% | 167,728 | +6.5% | 0.30% | 0.0% |
| New | Vivus Inc 4.5 05/01/2020note 4.500% 5/0 | $3,240,000 | – | 4,000,000 | +100.0% | 0.30% | – | |
| ARGX | Buy | ARGENX SEsponsored adr | $2,765,000 | +35.7% | 28,777 | +7.2% | 0.26% | +110.7% |
| LJPC | Sell | La Jolla Pharmaceutical Co | $2,528,000 | -89.5% | 268,036 | -77.6% | 0.24% | -83.7% |
| MRTX | New | Mirati Therapeutics Inc | $1,644,000 | – | 38,765 | +100.0% | 0.15% | – |
| MOTS | Buy | MOTUS GI HLDGS INC | $1,429,000 | +371.6% | 459,478 | +672.5% | 0.13% | +638.9% |
| PTI | Sell | PROTEOSTASIS THERAPEUTICS IN | $1,016,000 | -62.7% | 313,466 | -72.2% | 0.10% | -41.7% |
| LIVN | New | LIVANOVA PLCput | $723,000 | – | 7,900 | +100.0% | 0.07% | – |
| OPTN | New | Optinose Inc | $493,000 | – | 79,466 | +100.0% | 0.05% | – |
| RMED | Sell | RA MED SYS INC | $487,000 | -75.7% | 61,281 | -44.3% | 0.04% | -62.5% |
| BLCM | Exit | Bellicum Pharmaceuticals Inc | $0 | – | -157,489 | -100.0% | -0.06% | – |
| NVUS | Exit | Novus Therapeutics Inc | $0 | – | -316,257 | -100.0% | -0.09% | – |
| TPIV | Exit | Tapimmune Inc | $0 | – | -209,721 | -100.0% | -0.11% | – |
| Exit | VIVUS INCnote 4.500% 5/0 | $0 | – | -4,000,000 | -100.0% | -0.19% | – | |
| NVAX | Exit | Novavax Inc | $0 | – | -2,771,023 | -100.0% | -0.31% | – |
| NVTRQ | Exit | Nuvectra Corp | $0 | – | -251,329 | -100.0% | -0.33% | – |
| VKTX | Exit | Viking Therapeutics Inc | $0 | – | -500,000 | -100.0% | -0.52% | – |
| PACB | Exit | PACIFIC BIOSCIENCES CALIF IN | $0 | – | -2,237,607 | -100.0% | -0.72% | – |
| BVX | Exit | Bovie Medical Corp | $0 | – | -2,235,547 | -100.0% | -0.95% | – |
| RMD | Exit | ResMed Inc | $0 | – | -147,400 | -100.0% | -1.02% | – |
| QGEN | Exit | Qiagen NV | $0 | – | -775,324 | -100.0% | -1.76% | – |
| ILMN | Exit | Illumina Inc | $0 | – | -82,621 | -100.0% | -1.82% | – |
| CORI | Exit | CORIUM INTL INC | $0 | – | -3,610,632 | -100.0% | -2.06% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR/A filed 2019-02-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| ALNYLAM PHARMACEUTICALS INC | 36 | Q3 2023 | 19.7% |
| MASIMO CORP | 32 | Q3 2023 | 5.8% |
| LA JOLLA PHARMACEUTICAL CO | 31 | Q2 2022 | 9.7% |
| REGENXBIO INC | 30 | Q4 2022 | 10.8% |
| AGENUS INC | 29 | Q2 2022 | 9.0% |
| PTC THERAPEUTICS INC | 28 | Q3 2023 | 12.8% |
| DICERNA PHARMACEUTICALS INC | 28 | Q3 2021 | 10.8% |
| MIRATI THERAPEUTICS INC | 26 | Q3 2023 | 6.2% |
| ARGENX SE | 26 | Q3 2023 | 5.3% |
| VERICEL CORP | 24 | Q3 2023 | 3.9% |
View RTW INVESTMENTS, LP's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| ROCKET PHARMACEUTICALS, INC. | September 19, 2023 | 18,188,457 | - |
| ALLURION TECHNOLOGIES, INC. | August 11, 2023 | 3,457,707 | 7.4% |
| Orchestra BioMed Holdings, Inc. | May 05, 2023 | 5,620,645 | 15.7% |
| Renovacor, Inc.Sold out | April 05, 2023 | 0 | - |
| Adverum Biotechnologies, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Aptevo Therapeutics Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| ASLAN Pharmaceuticals LtdSold out | February 14, 2023 | 0 | 0.0% |
| Athira Pharma, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| BELLUS Health Inc.Sold out | February 14, 2023 | 0 | 0.0% |
| Clearside Biomedical, Inc.Sold out | February 14, 2023 | 0 | 0.0% |
View RTW INVESTMENTS, LP's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13D/A | 2024-04-17 |
| SC 13D/A | 2024-03-01 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View RTW INVESTMENTS, LP's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.