$370 Million is the total value of Sio Capital Management, LLC's 70 reported holdings in Q1 2019. The portfolio turnover from Q4 2018 to Q1 2019 was 66.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CVS | Buy | CVS HEALTH CORP | $19,796,000 | +108.7% | 367,071 | +153.5% | 5.34% | +54.7% |
| BIIB | New | BIOGEN INC | $18,579,000 | – | 78,596 | +100.0% | 5.02% | – |
| GILD | Buy | GILEAD SCIENCES INC | $15,990,000 | +165.0% | 245,968 | +154.9% | 4.32% | +96.4% |
| HCA | Buy | HCA HEALTHCARE INC | $14,006,000 | +65.4% | 107,428 | +57.9% | 3.78% | +22.6% |
| MDT | Buy | MEDTRONIC PLC | $11,974,000 | +0.4% | 131,464 | +0.3% | 3.23% | -25.6% |
| DRNA | Buy | DICERNA PHARMACEUTICALS INC | $11,236,000 | +137.0% | 766,980 | +73.0% | 3.03% | +75.7% |
| GSK | New | GLAXOSMITHKLINE PLCsponsored adr | $10,949,000 | – | 262,000 | +100.0% | 2.96% | – |
| MEDP | Buy | MEDPACE HOLDINGS INC | $10,725,000 | +220.7% | 181,866 | +187.9% | 2.90% | +137.8% |
| ASND | New | ASCENDIS PHARMA A/Ssponsored adr | $10,631,000 | – | 90,325 | +100.0% | 2.87% | – |
| GWPH | Sell | GW PHARMACEUTICALS PLCads | $10,483,000 | +27.9% | 62,186 | -26.1% | 2.83% | -5.2% |
| WBA | New | WALGREENS BOOTS ALLIANCE INCput | $10,471,000 | – | 165,500 | +100.0% | 2.83% | – |
| GMED | New | GLOBUS MEDICAL INCcl a | $10,022,000 | – | 202,827 | +100.0% | 2.71% | – |
| EBS | Buy | EMERGENT BIOSOLUTIONS INC | $9,101,000 | +108.1% | 180,156 | +144.1% | 2.46% | +54.2% |
| GWPH | New | GW PHARMACEUTICALS PLCput | $8,563,000 | – | 50,800 | +100.0% | 2.31% | – |
| NVO | Buy | NOVO NORDISK A/Sadr | $8,474,000 | +24.8% | 162,000 | +9.9% | 2.29% | -7.5% |
| VKTX | Buy | VIKING THERAPEUTICS INC | $8,470,000 | +73.8% | 852,160 | +33.8% | 2.29% | +28.8% |
| ALNY | Sell | ALNYLAM PHARMACEUTICALS INC | $7,397,000 | -34.4% | 79,153 | -48.8% | 2.00% | -51.4% |
| CCXI | Buy | CHEMOCENTRYX INC | $7,364,000 | +298.7% | 530,175 | +213.2% | 1.99% | +195.4% |
| MEIP | Sell | MEI PHARMA INC | $7,235,000 | +15.4% | 2,356,633 | -0.7% | 1.95% | -14.5% |
| SNY | Sell | SANOFI SAsponsored adr | $6,945,000 | -40.4% | 156,854 | -41.6% | 1.88% | -55.8% |
| MOH | Buy | MOLINA HEALTHCARE INC | $6,378,000 | +28.0% | 44,928 | +4.8% | 1.72% | -5.1% |
| MCK | Buy | MCKESSON CORP | $6,005,000 | +16.8% | 51,300 | +10.3% | 1.62% | -13.4% |
| SPPI | New | SPECTRUM PHARMACEUTICALS INC | $5,922,000 | – | 554,019 | +100.0% | 1.60% | – |
| WCG | New | WELLCARE HEALTH PLANS INC | $5,789,000 | – | 21,459 | +100.0% | 1.56% | – |
| ISRG | New | INTUITIVE SURGICAL INCput | $5,649,000 | – | 9,900 | +100.0% | 1.52% | – |
| VRTX | New | VERTEX PHARMACEUTICALS INC | $5,193,000 | – | 28,232 | +100.0% | 1.40% | – |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $4,859,000 | +17.5% | 1,295,669 | +12.5% | 1.31% | -12.9% |
| ALXN | Buy | ALEXION PHARMACEUTICALS INC | $4,788,000 | +189.3% | 35,421 | +108.4% | 1.29% | +114.4% |
| BNGO | Buy | BIONANO GENOMICS INC*w exp 08/21/2023 | $4,629,000 | -4.6% | 1,538,424 | +7.1% | 1.25% | -29.3% |
| STRO | Buy | SUTRO BIOPHARMA INC | $4,542,000 | +78.6% | 398,796 | +41.5% | 1.23% | +32.4% |
| SNN | Buy | SMITH & NEPHEW PLCspdn adr new | $4,425,000 | +15.9% | 110,327 | +8.0% | 1.20% | -14.1% |
| EGRX | New | EAGLE PHARMACEUTICALS INC | $4,276,000 | – | 84,695 | +100.0% | 1.15% | – |
| SYNH | New | SYNEOS HEALTH INCcl a | $4,239,000 | – | 81,899 | +100.0% | 1.14% | – |
| MRTX | New | MIRATI THERAPEUTICS INC | $4,163,000 | – | 56,800 | +100.0% | 1.12% | – |
| RIGL | Sell | RIGEL PHARMACEUTICALS INC | $4,136,000 | -17.5% | 1,609,265 | -26.2% | 1.12% | -38.9% |
| SRCL | New | STERICYCLE INC | $4,082,000 | – | 75,000 | +100.0% | 1.10% | – |
| PETS | New | PETMED EXPRESS INC | $4,058,000 | – | 178,151 | +100.0% | 1.10% | – |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $4,012,000 | +18.8% | 254,581 | +51.8% | 1.08% | -12.0% |
| UTHR | Buy | UNITED THERAPEUTICS CORP | $3,950,000 | +20.9% | 33,655 | +12.2% | 1.07% | -10.4% |
| VAR | New | VARIAN MEDICAL SYSTEMS INCput | $3,911,000 | – | 27,600 | +100.0% | 1.06% | – |
| ZBH | Sell | ZIMMER BIOMET HOLDINGS INC | $3,831,000 | +5.1% | 30,000 | -14.6% | 1.03% | -22.1% |
| UNH | Buy | UNITEDHEALTH GROUP INC | $3,810,000 | +7.7% | 15,407 | +8.4% | 1.03% | -20.2% |
| SYK | New | STRYKER CORPput | $3,792,000 | – | 19,200 | +100.0% | 1.02% | – |
| IDXX | New | IDEXX LABORATORIES INCput | $3,779,000 | – | 16,900 | +100.0% | 1.02% | – |
| CBIO | Buy | CATALYST BIOSCIENCES INC | $3,684,000 | +60.1% | 454,308 | +55.8% | 1.00% | +18.7% |
| PEN | Sell | PENUMBRA INCput | $3,528,000 | -15.1% | 24,000 | -29.4% | 0.95% | -37.0% |
| CBAY | Buy | CYMABAY THERAPEUTICS INC | $3,185,000 | +116.1% | 239,827 | +28.0% | 0.86% | +60.1% |
| ICLR | Buy | ICON PLC | $3,069,000 | +10.1% | 22,471 | +4.2% | 0.83% | -18.3% |
| HUM | Sell | HUMANA INC | $2,877,000 | -38.4% | 10,817 | -33.7% | 0.78% | -54.3% |
| HROW | Buy | HARROW HEALTH INC | $2,695,000 | +41.2% | 541,114 | +61.4% | 0.73% | +4.7% |
| ICPT | New | INTERCEPT PHARMACEUTICALS INCput | $2,439,000 | – | 21,800 | +100.0% | 0.66% | – |
| GNFT | New | GENFIT SAads | $2,223,000 | – | 92,637 | +100.0% | 0.60% | – |
| UROV | Sell | UROVANT SCIENCES LTD | $2,161,000 | -59.4% | 215,042 | -73.4% | 0.58% | -69.9% |
| VICL | VICAL INC | $1,939,000 | +1.7% | 1,615,887 | 0.0% | 0.52% | -24.6% | |
| LOGC | LOGICBIO THERAPEUTICS INC | $1,571,000 | -5.0% | 158,958 | 0.0% | 0.42% | -29.6% | |
| INGN | Buy | INOGEN INC | $1,449,000 | -9.0% | 15,189 | +18.4% | 0.39% | -32.6% |
| SENS | Buy | SENSEONICS HOLDINGS INC | $1,359,000 | +9.3% | 554,858 | +15.6% | 0.37% | -19.0% |
| ACHV | Sell | ACHIEVE LIFE SCIENCES INC | $1,361,000 | +88.2% | 421,479 | -29.4% | 0.37% | +39.5% |
| IDXG | New | INTERPACE DIAGNOSTICS GROUP INC | $1,322,000 | – | 1,653,097 | +100.0% | 0.36% | – |
| PFNX | PFENEX INC | $1,320,000 | +93.8% | 213,608 | 0.0% | 0.36% | +43.5% | |
| OSMT | OSMOTICA PHARMACEUTICALS PLC | $1,247,000 | -53.6% | 346,410 | 0.0% | 0.34% | -65.5% | |
| AFMD | Buy | AFFIMED NV | $1,125,000 | +123.7% | 267,942 | +65.8% | 0.30% | +66.1% |
| HRC | Sell | HILL-ROM HOLDINGS INC | $1,025,000 | -53.1% | 9,682 | -60.8% | 0.28% | -65.2% |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $603,000 | -43.9% | 42,410 | -88.9% | 0.16% | -58.3% |
| RMED | Sell | RA MEDICAL SYSTEMS INC | $590,000 | -84.7% | 173,652 | -64.3% | 0.16% | -88.7% |
| MASI | New | MASIMO CORPput | $456,000 | – | 3,300 | +100.0% | 0.12% | – |
| BPMC | New | BLUEPRINT MEDICINES CORP | $240,000 | – | 3,000 | +100.0% | 0.06% | – |
| ATNM | ACTINIUM PHARMACEUTICALS INC | $163,000 | +23.5% | 339,796 | 0.0% | 0.04% | -8.3% | |
| LXRX | LEXICON PHARMACEUTICALS INCput | $120,000 | -16.1% | 21,600 | 0.0% | 0.03% | -38.5% | |
| IMMU | Exit | IMMUNOMEDICS INC | $0 | – | -25,900 | -100.0% | -0.14% | – |
| CFMS | Exit | CONFORMIS INC | $0 | – | -1,121,894 | -100.0% | -0.15% | – |
| TMDI | Exit | TITAN MEDICAL INC | $0 | – | -445,680 | -100.0% | -0.20% | – |
| VCYT | Exit | VERACYTE INC | $0 | – | -70,199 | -100.0% | -0.32% | – |
| IVC | Exit | INVACARE CORP | $0 | – | -247,196 | -100.0% | -0.39% | – |
| ESTA | Exit | ESTABLISHMENT LABS HOLDINGS INC | $0 | – | -52,701 | -100.0% | -0.53% | – |
| PHG | Exit | KONINKLIJKE PHILIPS NVny reg sh new | $0 | – | -50,000 | -100.0% | -0.64% | – |
| KURA | Exit | KURA ONCOLOGY INC | $0 | – | -144,411 | -100.0% | -0.74% | – |
| XRAY | Exit | DENTSPLY SIRONA INC | $0 | – | -65,666 | -100.0% | -0.89% | – |
| BMY | Exit | BRISTOL-MYERS SQUIBB CO | $0 | – | -50,000 | -100.0% | -0.95% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -17,000 | -100.0% | -1.20% | – |
| ABT | Exit | ABBOTT LABORATORIES | $0 | – | -48,737 | -100.0% | -1.28% | – |
| BDX | Exit | BECTON DICKINSON AND CO | $0 | – | -16,000 | -100.0% | -1.31% | – |
| ALGN | Exit | ALIGN TECHNOLOGY INC | $0 | – | -17,847 | -100.0% | -1.36% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -69,000 | -100.0% | -1.80% | – |
| PINC | Exit | PREMIER INCcl a | $0 | – | -134,412 | -100.0% | -1.83% | – |
| MYL | Exit | MYLAN NV | $0 | – | -187,175 | -100.0% | -1.87% | – |
| CELG | Exit | CELGENE CORP | $0 | – | -102,390 | -100.0% | -2.39% | – |
| CAH | Exit | CARDINAL HEALTH INC | $0 | – | -209,009 | -100.0% | -3.40% | – |
| AMGN | Exit | AMGEN INCput | $0 | – | -50,000 | -100.0% | -3.55% | – |
| CI | Exit | CIGNA CORP | $0 | – | -52,216 | -100.0% | -3.61% | – |
| ABC | Exit | AMERISOURCEBERGEN CORP | $0 | – | -133,934 | -100.0% | -3.63% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-05-15
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.