$275 Million is the total value of Sio Capital Management, LLC's 69 reported holdings in Q4 2018. The portfolio turnover from Q3 2018 to Q4 2018 was 90.5% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MDT | Buy | MEDTRONIC PLC | $11,926,000 | +244.5% | 131,115 | +272.5% | 4.34% | +265.7% |
| SNY | Buy | SANOFI SAsponsored adr | $11,651,000 | -2.1% | 268,388 | +0.8% | 4.24% | +3.9% |
| ALNY | Buy | ALNYLAM PHARMACEUTICALS INC | $11,275,000 | +23.7% | 154,637 | +48.4% | 4.11% | +31.3% |
| ABC | New | AMERISOURCEBERGEN CORP | $9,965,000 | – | 133,934 | +100.0% | 3.63% | – |
| CI | New | CIGNA CORP | $9,917,000 | – | 52,216 | +100.0% | 3.61% | – |
| AMGN | AMGEN INCput | $9,734,000 | -6.1% | 50,000 | 0.0% | 3.55% | -0.3% | |
| CVS | New | CVS HEALTH CORP | $9,486,000 | – | 144,777 | +100.0% | 3.46% | – |
| CAH | Buy | CARDINAL HEALTH INC | $9,322,000 | +178.4% | 209,009 | +237.1% | 3.40% | +195.6% |
| HCA | Sell | HCA HEALTHCARE INC | $8,467,000 | -27.4% | 68,039 | -18.8% | 3.08% | -22.9% |
| GWPH | New | GW PHARMACEUTICALS PLCads | $8,199,000 | – | 84,186 | +100.0% | 2.99% | – |
| NVO | New | NOVO NORDISK A/Sadr | $6,790,000 | – | 147,378 | +100.0% | 2.47% | – |
| CELG | New | CELGENE CORP | $6,562,000 | – | 102,390 | +100.0% | 2.39% | – |
| MEIP | Buy | MEI PHARMA INC | $6,267,000 | -36.9% | 2,373,841 | +3.0% | 2.28% | -33.0% |
| GILD | New | GILEAD SCIENCES INC | $6,035,000 | – | 96,480 | +100.0% | 2.20% | – |
| UROV | Buy | UROVANT SCIENCES LTD | $5,324,000 | -25.0% | 807,860 | +36.6% | 1.94% | -20.4% |
| MCK | New | MCKESSON CORP | $5,140,000 | – | 46,530 | +100.0% | 1.87% | – |
| MYL | New | MYLAN NV | $5,129,000 | – | 187,175 | +100.0% | 1.87% | – |
| PINC | Sell | PREMIER INCcl a | $5,020,000 | -24.1% | 134,412 | -6.9% | 1.83% | -19.4% |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $5,015,000 | -15.3% | 2,180,546 | +18.3% | 1.83% | -10.0% |
| MOH | New | MOLINA HEALTHCARE INC | $4,982,000 | – | 42,869 | +100.0% | 1.82% | – |
| NBIX | New | NEUROCRINE BIOSCIENCES INC | $4,927,000 | – | 69,000 | +100.0% | 1.80% | – |
| VKTX | Buy | VIKING THERAPEUTICS INC | $4,873,000 | +31.2% | 637,046 | +198.7% | 1.78% | +39.2% |
| BNGO | Sell | BIONANO GENOMICS INC*w exp 08/21/2023 | $4,854,000 | -34.0% | 1,436,461 | -0.3% | 1.77% | -29.9% |
| DRNA | New | DICERNA PHARMACEUTICALS INC | $4,740,000 | – | 443,409 | +100.0% | 1.73% | – |
| HUM | Sell | HUMANA INC | $4,674,000 | -31.2% | 16,317 | -18.6% | 1.70% | -26.9% |
| EBS | Buy | EMERGENT BIOSOLUTIONS INC | $4,374,000 | +58.9% | 73,793 | +76.5% | 1.59% | +68.8% |
| PEN | New | PENUMBRA INCput | $4,155,000 | – | 34,000 | +100.0% | 1.51% | – |
| FOMX | Buy | FOAMIX PHARMACEUTICALS LTD | $4,134,000 | -6.3% | 1,151,510 | +49.5% | 1.51% | -0.5% |
| RMED | Buy | RA MEDICAL SYSTEMS INC | $3,865,000 | +56.7% | 486,107 | +258.6% | 1.41% | +66.4% |
| SNN | Sell | SMITH & NEPHEW PLCspdn adr new | $3,819,000 | -23.4% | 102,163 | -24.0% | 1.39% | -18.7% |
| ALGN | New | ALIGN TECHNOLOGY INC | $3,738,000 | – | 17,847 | +100.0% | 1.36% | – |
| ZBH | New | ZIMMER BIOMET HOLDINGS INC | $3,645,000 | – | 35,144 | +100.0% | 1.33% | – |
| BDX | New | BECTON DICKINSON AND CO | $3,605,000 | – | 16,000 | +100.0% | 1.31% | – |
| UNH | Buy | UNITEDHEALTH GROUP INC | $3,539,000 | +5.7% | 14,207 | +12.9% | 1.29% | +12.3% |
| ABT | Buy | ABBOTT LABORATORIES | $3,525,000 | +238.0% | 48,737 | +242.7% | 1.28% | +258.7% |
| RVNC | Buy | REVANCE THERAPEUTICS INC | $3,376,000 | -17.3% | 167,724 | +2.1% | 1.23% | -12.2% |
| MEDP | New | MEDPACE HOLDINGS INC | $3,344,000 | – | 63,180 | +100.0% | 1.22% | – |
| AMGN | New | AMGEN INC | $3,309,000 | – | 17,000 | +100.0% | 1.20% | – |
| UTHR | New | UNITED THERAPEUTICS CORP | $3,267,000 | – | 30,000 | +100.0% | 1.19% | – |
| ICLR | Sell | ICON PLC | $2,787,000 | -21.9% | 21,566 | -7.0% | 1.02% | -17.1% |
| OSMT | New | OSMOTICA PHARMACEUTICALS PLC | $2,685,000 | – | 346,410 | +100.0% | 0.98% | – |
| BMY | New | BRISTOL-MYERS SQUIBB CO | $2,599,000 | – | 50,000 | +100.0% | 0.95% | – |
| STRO | Buy | SUTRO BIOPHARMA INC | $2,543,000 | -27.1% | 281,914 | +21.2% | 0.93% | -22.6% |
| XRAY | New | DENTSPLY SIRONA INC | $2,443,000 | – | 65,666 | +100.0% | 0.89% | – |
| CBIO | Sell | CATALYST BIOSCIENCES INC | $2,301,000 | -61.3% | 291,625 | -47.1% | 0.84% | -58.9% |
| HRC | Buy | HILL-ROM HOLDINGS INC | $2,186,000 | -3.7% | 24,682 | +2.7% | 0.80% | +2.2% |
| KURA | Sell | KURA ONCOLOGY INC | $2,028,000 | -84.1% | 144,411 | -80.1% | 0.74% | -83.1% |
| VICL | Buy | VICAL INC | $1,907,000 | +12.2% | 1,615,887 | +30.3% | 0.70% | +19.2% |
| HROW | New | IMPRIMIS PHARMACEUTICALS, INC. | $1,908,000 | – | 335,364 | +100.0% | 0.70% | – |
| CCXI | New | CHEMOCENTRYX INC | $1,847,000 | – | 169,257 | +100.0% | 0.67% | – |
| PHG | Sell | KONINKLIJKE PHILIPS NVny reg sh new | $1,756,000 | -59.7% | 50,000 | -47.8% | 0.64% | -57.2% |
| ALXN | Sell | ALEXION PHARMACEUTICALS INC | $1,655,000 | -53.8% | 17,000 | -34.1% | 0.60% | -51.0% |
| LOGC | New | LOGICBIO THERAPEUTICS INC | $1,653,000 | – | 158,958 | +100.0% | 0.60% | – |
| INGN | New | INOGEN INC | $1,592,000 | – | 12,824 | +100.0% | 0.58% | – |
| CBAY | New | CYMABAY THERAPEUTICS INC | $1,474,000 | – | 187,327 | +100.0% | 0.54% | – |
| ESTA | Buy | ESTABLISHMENT LABS HOLDINGS INC | $1,445,000 | +34.2% | 52,701 | +18.0% | 0.53% | +42.2% |
| SENS | Buy | SENSEONICS HOLDINGS INC | $1,243,000 | -35.2% | 479,858 | +19.2% | 0.45% | -31.2% |
| AXSM | Sell | AXSOME THERAPEUTICS INC | $1,074,000 | -25.3% | 380,812 | -8.6% | 0.39% | -20.7% |
| IVC | New | INVACARE CORP | $1,063,000 | – | 247,196 | +100.0% | 0.39% | – |
| VCYT | New | VERACYTE INC | $883,000 | – | 70,199 | +100.0% | 0.32% | – |
| ACHV | Buy | ACHIEVE LIFE SCIENCES INC | $723,000 | +38.2% | 597,373 | +259.9% | 0.26% | +46.9% |
| PFNX | PFENEX INC | $681,000 | -37.6% | 213,608 | 0.0% | 0.25% | -33.9% | |
| TMDI | TITAN MEDICAL INC | $544,000 | -42.7% | 445,680 | 0.0% | 0.20% | -39.3% | |
| AFMD | Sell | AFFIMED NV | $503,000 | -79.3% | 161,635 | -71.0% | 0.18% | -78.0% |
| CFMS | Sell | CONFORMIS INC | $402,000 | -79.6% | 1,121,894 | -39.7% | 0.15% | -78.4% |
| IMMU | New | IMMUNOMEDICS INC | $370,000 | – | 25,900 | +100.0% | 0.14% | – |
| LXRX | LEXICON PHARMACEUTICALS INCput | $143,000 | -37.8% | 21,600 | 0.0% | 0.05% | -34.2% | |
| ATNM | New | ACTINIUM PHARMACEUTICALS INC | $132,000 | – | 339,796 | +100.0% | 0.05% | – |
| VTL | Exit | VITAL THERAPIES INC | $0 | – | -103,707 | -100.0% | -0.01% | – |
| VTL | Exit | VITAL THERAPIES INCput | $0 | – | -194,700 | -100.0% | -0.02% | – |
| GTXI | Exit | GTX INCput | $0 | – | -51,500 | -100.0% | -0.03% | – |
| OPTN | Exit | OPTINOSE INC | $0 | – | -27,068 | -100.0% | -0.12% | – |
| SPPI | Exit | SPECTRUM PHARMACEUTICALS INC | $0 | – | -70,712 | -100.0% | -0.41% | – |
| ECOR | Exit | ELECTROCORE, INC. | $0 | – | -86,120 | -100.0% | -0.41% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -32,832 | -100.0% | -0.52% | – |
| AKCA | Exit | AKCEA THERAPEUTICS INCput | $0 | – | -43,300 | -100.0% | -0.52% | – |
| ABUS | Exit | ARBUTUS BIOPHARMA CORP | $0 | – | -164,943 | -100.0% | -0.54% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS INC | $0 | – | -114,259 | -100.0% | -0.75% | – |
| NVRO | Exit | NEVRO CORP | $0 | – | -45,091 | -100.0% | -0.88% | – |
| PFE | Exit | PFIZER INCput | $0 | – | -71,500 | -100.0% | -1.08% | – |
| AGN | Exit | ALLERGAN PLCput | $0 | – | -17,500 | -100.0% | -1.14% | – |
| AZN | Exit | ASTRAZENECA PLCput | $0 | – | -87,400 | -100.0% | -1.19% | – |
| AMGN | Exit | AMGEN INCcall | $0 | – | -20,000 | -100.0% | -1.42% | – |
| AMAG | Exit | AMAG PHARMACEUTICALS INCput | $0 | – | -226,200 | -100.0% | -1.55% | – |
| NVS | Exit | NOVARTIS AGsponsored adr | $0 | – | -57,691 | -100.0% | -1.71% | – |
| UHS | Exit | UNIVERSAL HEALTH SERVICES INCcl b | $0 | – | -41,393 | -100.0% | -1.82% | – |
| MRK | Exit | MERCK & CO INCcall | $0 | – | -84,000 | -100.0% | -2.04% | – |
| XRAY | Exit | DENTSPLY SIRONA INCput | $0 | – | -170,000 | -100.0% | -2.20% | – |
| ANTM | Exit | ANTHEM INC | $0 | – | -24,803 | -100.0% | -2.33% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -19,300 | -100.0% | -2.34% | – |
| AET | Exit | AETNA INC | $0 | – | -60,444 | -100.0% | -4.21% | – |
| PCRX | Exit | PACIRA PHARMACEUTICALS INCput | $0 | – | -281,100 | -100.0% | -4.74% | – |
| CI | Exit | CIGNA CORP | $0 | – | -67,449 | -100.0% | -4.82% | – |
| GSK | Exit | GLAXOSMITHKLINE PLCsponsored adr | $0 | – | -363,960 | -100.0% | -5.02% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2019-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| VIKING THERAPEUTICS INC | 24 | Q3 2023 | 3.4% |
| UNITED THERAPEUTICS ORD | 23 | Q3 2023 | 8.3% |
| CARDINAL HEALTH ORD | 20 | Q2 2022 | 7.2% |
| SANOFI SA | 19 | Q3 2022 | 9.8% |
| MEDTRONIC PLC | 18 | Q3 2023 | 5.2% |
| CATALYST BIOSCIENCES INC | 18 | Q3 2021 | 17.8% |
| PFENEX ORD | 18 | Q4 2019 | 5.9% |
| AEGLEA BIOTHERAPEUTICS INC | 18 | Q1 2023 | 1.1% |
| HCA HEALTHCARE INC | 17 | Q2 2022 | 5.5% |
| MCKESSON ORD | 17 | Q1 2022 | 6.0% |
View Sio Capital Management, LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Modular Medical, Inc. | February 13, 2023 | 1,091,479 | 10.0% |
| Cellectar Biosciences, Inc. | February 10, 2022 | ? | ? |
| CURIS INC | February 10, 2022 | 3,866,645 | 4.2% |
| Salarius Pharmaceuticals, Inc. | February 10, 2022 | 1,354,291 | 3.0% |
| Larimar Therapeutics, Inc. | February 16, 2021 | 188,661 | 1.2% |
| ACHIEVE LIFE SCIENCES, INC. | February 14, 2020 | ? | ? |
| Bionano Genomics, Inc | February 14, 2020 | 1,210,821 | 4.6% |
| Brickell Biotech, Inc. | February 14, 2020 | ? | ? |
| Trillium Therapeutics Inc. | February 14, 2020 | 2,751,186 | 9.8% |
| ZAFGEN, INC. | February 14, 2020 | 2,283,164 | 6.1% |
View Sio Capital Management, LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G/A | 2024-02-14 |
| SC 13G | 2024-02-14 |
| SC 13G | 2024-02-14 |
| 13F-HR | 2024-02-13 |
| 13F-HR | 2023-11-14 |
| 13F-HR | 2023-08-14 |
| 13F-HR | 2023-05-12 |
| 13F-HR | 2023-02-13 |
| SC 13G | 2023-02-13 |
| 13F-HR | 2022-11-14 |
View Sio Capital Management, LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.