$2.65 Billion is the total value of Tekla Capital Management LLC's 172 reported holdings in Q4 2022. The portfolio turnover from Q3 2022 to Q4 2022 was 13.1% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UNH | Sell | Unitedhealth Group Inc. | $143,438,078 | +3.6% | 270,546 | -1.3% | 5.42% | -4.4% |
| AMGN | Sell | Amgen Inc. | $133,598,665 | +14.2% | 508,676 | -2.0% | 5.05% | +5.4% |
| GILD | Sell | Gilead Sciences, Inc. | $129,671,274 | +29.6% | 1,510,440 | -6.9% | 4.90% | +19.5% |
| JNJ | Sell | Johnson & Johnson | $112,999,295 | -11.7% | 639,679 | -18.4% | 4.27% | -18.6% |
| LLY | Buy | Eli Lilly and Company | $105,697,395 | +35.9% | 288,917 | +20.1% | 3.99% | +25.3% |
| VRTX | Buy | Vertex Pharmaceuticals Inc. | $95,396,452 | +5.1% | 330,343 | +5.4% | 3.60% | -3.0% |
| REGN | Buy | Regeneron Pharmaceuticals, Inc. | $87,200,724 | +16.1% | 120,862 | +10.8% | 3.29% | +7.1% |
| ABBV | Sell | AbbVie Inc. | $77,304,851 | +9.3% | 478,342 | -9.2% | 2.92% | +0.9% |
| ABT | Sell | Abbott Laboratories | $76,090,069 | -0.6% | 693,051 | -12.4% | 2.87% | -8.3% |
| PFE | Buy | Pfizer Inc. | $74,665,391 | +50.7% | 1,457,170 | +28.7% | 2.82% | +39.1% |
| AZN | Sell | AstraZeneca PLCsponsored adr | $69,308,889 | -0.7% | 1,022,255 | -19.7% | 2.62% | -8.4% |
| ILMN | Buy | Illumina, Inc. | $64,695,508 | +15.0% | 319,958 | +8.5% | 2.44% | +6.0% |
| MRK | Merck & Co., Inc. | $61,257,936 | +28.8% | 552,122 | 0.0% | 2.31% | +18.8% | |
| CI | Sell | Cigna Corp. | $60,512,956 | +3.5% | 182,631 | -13.3% | 2.28% | -4.6% |
| BIIB | Buy | Biogen Inc. | $54,118,476 | +39.4% | 195,430 | +34.4% | 2.04% | +28.6% |
| TMO | Thermo Fisher Scientific Inc. | $51,602,406 | +8.6% | 93,705 | 0.0% | 1.95% | +0.2% | |
| BMY | Sell | Bristol-Myers Squibb Company | $49,467,712 | -20.9% | 687,529 | -21.8% | 1.87% | -27.0% |
| MRNA | Sell | Moderna, Inc. | $47,586,188 | +27.8% | 264,927 | -15.9% | 1.80% | +17.8% |
| HZNP | Sell | Horizon Therapeutics plc | $47,233,031 | +3.9% | 415,053 | -43.5% | 1.78% | -4.1% |
| SYK | Sell | Stryker Corp. | $40,127,655 | +2.4% | 164,128 | -15.2% | 1.52% | -5.6% |
| HUM | Sell | Humana Inc. | $39,803,821 | -27.4% | 77,713 | -31.2% | 1.50% | -33.1% |
| BSX | Sell | Boston Scientific Corp. | $35,027,084 | +13.7% | 757,015 | -4.8% | 1.32% | +4.9% |
| ALNY | Alnylam Pharmaceuticals, Inc. | $34,034,807 | +18.7% | 143,214 | 0.0% | 1.28% | +9.5% | |
| ZBH | Zimmer Biomet Holdings, Inc. | $33,005,670 | +21.9% | 258,868 | 0.0% | 1.25% | +12.5% | |
| UTHR | Sell | United Therapeutics Corp. | $32,001,763 | +30.2% | 115,077 | -2.0% | 1.21% | +20.2% |
| ARGX | Buy | argenx SEsponsored adr | $31,829,675 | +17.6% | 84,021 | +9.6% | 1.20% | +8.5% |
| ISRG | Buy | Intuitive Surgical, Inc. | $29,899,638 | +52.8% | 112,680 | +7.9% | 1.13% | +40.9% |
| JAZZ | Jazz Pharmaceuticals plcshares | $29,119,000 | +19.5% | 182,782 | 0.0% | 1.10% | +10.3% | |
| DHR | Sell | Danaher Corp. | $28,052,240 | -12.8% | 105,690 | -15.1% | 1.06% | -19.6% |
| IDXX | Buy | IDEXX Laboratories, Inc. | $27,767,797 | +57.2% | 68,065 | +25.6% | 1.05% | +45.1% |
| MDT | Medtronic plcshares | $25,350,088 | -3.8% | 326,172 | 0.0% | 0.96% | -11.2% | |
| HCA | Sell | HCA Healthcare, Inc. | $25,196,520 | +10.3% | 105,003 | -15.5% | 0.95% | +1.8% |
| MCK | Buy | McKesson Corp. | $24,928,600 | +117.9% | 66,455 | +97.4% | 0.94% | +101.1% |
| DXCM | Sell | Dexcom, Inc. | $24,688,019 | +24.7% | 218,015 | -11.3% | 0.93% | +15.1% |
| MOH | Sell | Molina Healthcare, Inc. | $24,309,145 | -38.3% | 73,615 | -38.4% | 0.92% | -43.1% |
| BMRN | Buy | BioMarin Pharmaceutical Inc. | $23,884,457 | +86.7% | 230,790 | +52.9% | 0.90% | +72.1% |
| ZTS | Zoetis Inc.class a | $20,064,747 | -1.2% | 136,914 | 0.0% | 0.76% | -8.8% | |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $18,265,467 | -0.4% | 140,959 | -15.1% | 0.69% | -8.1% |
| NVO | Novo Nordisk A/Ssponsored adr | $17,664,983 | +35.8% | 130,523 | 0.0% | 0.67% | +25.4% | |
| LNTH | Buy | Lantheus Holdings, Inc. | $17,472,757 | +8.4% | 342,872 | +49.6% | 0.66% | 0.0% |
| CRL | Charles River Laboratories International, Inc. | $15,835,883 | +10.7% | 72,675 | 0.0% | 0.60% | +2.0% | |
| BNTX | Buy | BioNTech SEsponsored ads | $15,601,549 | +21.7% | 103,858 | +9.3% | 0.59% | +12.2% |
| ASND | Buy | Ascendis Pharma A/Ssponsored adr | $15,118,595 | +116.0% | 123,791 | +82.6% | 0.57% | +99.0% |
| QURE | Buy | uniQure N.V.shares | $14,790,951 | +51.1% | 652,446 | +25.1% | 0.56% | +39.4% |
| SGEN | Buy | Seagen Inc. | $14,420,621 | +97.4% | 112,214 | +110.2% | 0.54% | +82.3% |
| NBIX | Sell | Neurocrine Biosciences, Inc. | $13,485,732 | -24.5% | 112,908 | -32.8% | 0.51% | -30.4% |
| IQV | Sell | IQVIA Holdings Inc. | $12,932,042 | +5.3% | 63,117 | -6.9% | 0.49% | -3.0% |
| GH | Buy | Guardant Health, Inc. | $12,843,405 | -31.1% | 472,184 | +36.4% | 0.48% | -36.4% |
| EW | Edwards Lifesciences Corp. | $12,787,259 | -9.7% | 171,388 | 0.0% | 0.48% | -16.7% | |
| RMD | ResMed Inc. | $12,633,283 | -4.7% | 60,699 | 0.0% | 0.48% | -12.0% | |
| NVS | Novartis AGsponsored adr | $12,358,332 | +19.4% | 136,225 | 0.0% | 0.47% | +10.1% | |
| XBI | SPDR S&P Biotech ETFs&p biotech etf | $12,257,191 | +4.6% | 147,677 | 0.0% | 0.46% | -3.5% | |
| ACHC | Acadia Healthcare Company, Inc. | $11,622,678 | +5.3% | 141,189 | 0.0% | 0.44% | -2.9% | |
| Sell | Rallybio Corporation | $11,346,830 | -55.0% | 1,727,067 | -0.8% | 0.43% | -58.4% | |
| ALGN | Buy | Align Technology, Inc. | $10,718,782 | +173.9% | 50,824 | +169.0% | 0.40% | +153.1% |
| KRTX | Buy | Karuna Therapeutics, Inc. | $10,503,318 | +97.7% | 53,452 | +126.3% | 0.40% | +82.9% |
| LH | Laboratory Corporation of America Holdings | $10,394,558 | +15.0% | 44,142 | 0.0% | 0.39% | +6.2% | |
| AVTR | New | Avantor, Inc. | $9,690,602 | – | 459,488 | +100.0% | 0.37% | – |
| ITCI | Intra-Cellular Therapies, Inc. | $9,121,873 | +13.7% | 172,371 | 0.0% | 0.34% | +5.2% | |
| TVTX | Buy | Travere Therapeutics, Inc. | $8,801,476 | +44.2% | 418,520 | +69.0% | 0.33% | +32.8% |
| CVS | Sell | CVS Health Corp. | $8,724,541 | -26.1% | 93,621 | -24.4% | 0.33% | -31.9% |
| OHI | Omega Healthcare Investors, Inc. | $8,564,802 | -5.2% | 306,433 | 0.0% | 0.32% | -12.7% | |
| ALKS | Alkermes plcshares | $8,090,188 | +17.0% | 309,613 | 0.0% | 0.31% | +8.1% | |
| BCRX | Buy | BioCryst Pharmaceuticals, Inc. | $7,722,653 | +75.3% | 672,705 | +92.4% | 0.29% | +62.2% |
| DNLI | Buy | Denali Therapeutics, Inc. | $7,578,781 | +11.0% | 272,520 | +22.5% | 0.29% | +2.5% |
| MDRX | Allscripts Healthcare Solutions, Inc. | $7,560,151 | +15.8% | 428,580 | 0.0% | 0.29% | +7.1% | |
| ANTM | Elevance Health, Inc. | $7,511,933 | +12.9% | 14,644 | 0.0% | 0.28% | +4.4% | |
| HQY | HealthEquity, Inc. | $6,793,591 | -8.2% | 110,214 | 0.0% | 0.26% | -15.2% | |
| LTC | LTC Properties, Inc. | $6,476,870 | -5.1% | 182,293 | 0.0% | 0.24% | -12.2% | |
| A | Agilent Technologies, Inc. | $6,463,533 | +23.1% | 43,191 | 0.0% | 0.24% | +13.5% | |
| SBRA | Sabra Health Care REIT, Inc. | $6,347,504 | -5.3% | 510,660 | 0.0% | 0.24% | -12.4% | |
| VECT | Sell | VectivBio Holding AG | $6,351,631 | +39.9% | 737,704 | -2.5% | 0.24% | +29.0% |
| SNY | Sanofisponsored adr | $5,978,877 | +27.4% | 123,454 | 0.0% | 0.23% | +17.7% | |
| CTLT | New | Catalent, Inc. | $5,668,874 | – | 125,947 | +100.0% | 0.21% | – |
| CERE | Cerevel Therapeutics Holdings, Inc. | $5,566,274 | +11.6% | 176,483 | 0.0% | 0.21% | +2.9% | |
| NTLA | Intellia Therapeutics, Inc. | $5,382,445 | -37.7% | 154,269 | 0.0% | 0.20% | -42.5% | |
| XNCR | Xencor, Inc. | $5,216,541 | +0.2% | 200,328 | 0.0% | 0.20% | -7.5% | |
| SNN | Smith & Nephew plcsponsored adr | $4,886,182 | +15.8% | 181,710 | 0.0% | 0.18% | +6.9% | |
| BGNE | BeiGene, Ltd.sponsored adr | $4,608,183 | +63.1% | 20,952 | 0.0% | 0.17% | +50.0% | |
| MPW | Medical Properties Trust, Inc. | $4,586,817 | -6.1% | 411,743 | 0.0% | 0.17% | -13.5% | |
| ADUS | Sell | Addus HomeCare Corp. | $4,216,386 | -47.1% | 42,380 | -49.3% | 0.16% | -51.2% |
| RXDX | Buy | Prometheus Biosciences, Inc. | $4,206,070 | +126.3% | 38,237 | +21.4% | 0.16% | +109.2% |
| TEVA | Teva Pharmaceutical Industries Ltd.sponsored adr | $4,192,017 | +13.0% | 459,651 | 0.0% | 0.16% | +3.9% | |
| ARWR | Sell | Arrowhead Pharmaceuticals, Inc. | $4,073,116 | -21.4% | 100,422 | -36.0% | 0.15% | -27.4% |
| PEAK | Healthpeak Properties, Inc. | $3,770,327 | +9.4% | 150,392 | 0.0% | 0.14% | +0.7% | |
| Caribou Biosciences, Inc. | $3,561,683 | -40.5% | 567,147 | 0.0% | 0.14% | -44.9% | ||
| KURA | New | Kura Oncology, Inc. | $3,515,517 | – | 283,281 | +100.0% | 0.13% | – |
| APLS | Sell | Apellis Pharmaceuticals, Inc. | $3,434,888 | -81.1% | 66,426 | -75.0% | 0.13% | -82.5% |
| CYTK | Cytokinetics, Inc. | $3,442,869 | -5.4% | 75,139 | 0.0% | 0.13% | -12.8% | |
| ABC | New | Amerisourcebergen Corp. | $3,383,301 | – | 20,417 | +100.0% | 0.13% | – |
| Healthcare Realty Trust Inc. | $3,366,199 | -7.6% | 174,686 | 0.0% | 0.13% | -14.8% | ||
| IONS | Ionis Pharmaceuticals, Inc. | $3,317,717 | -14.6% | 87,840 | 0.0% | 0.12% | -21.4% | |
| XENE | Buy | Xenon Pharmaceuticals Inc. | $3,300,843 | +48.1% | 83,714 | +35.6% | 0.12% | +37.4% |
| IBB | Ishares Biothechnology ETF | $3,225,664 | +12.2% | 24,569 | 0.0% | 0.12% | +3.4% | |
| ADPT | Adaptive Biotechnologies Corp. | $3,226,227 | +7.3% | 422,281 | 0.0% | 0.12% | -0.8% | |
| MoonLake Immunotherapeutics AG | $3,150,000 | +31.9% | 300,000 | 0.0% | 0.12% | +21.4% | ||
| RARE | Ultragenyx Pharmaceutical Inc. | $3,107,121 | +11.9% | 67,065 | 0.0% | 0.12% | +2.6% | |
| STE | STERIS plcshares | $3,078,598 | +11.1% | 16,669 | 0.0% | 0.12% | +2.7% | |
| SNDX | New | Syndax Pharmaceuticals, Inc. | $2,995,898 | – | 117,717 | +100.0% | 0.11% | – |
| VTR | Ventas, Inc. | $3,003,979 | +12.1% | 66,681 | 0.0% | 0.11% | +2.7% | |
| MRTX | Sell | Mirati Therapeutics, Inc. | $2,967,352 | -65.3% | 65,490 | -46.5% | 0.11% | -68.0% |
| BPMC | New | Blueprint Medicines Corp. | $2,966,375 | – | 67,710 | +100.0% | 0.11% | – |
| WELL | Welltower Inc. | $2,719,276 | +1.9% | 41,484 | 0.0% | 0.10% | -5.5% | |
| BCYC | Bicycle Therapeutics PLCsponsored ads | $2,624,810 | +27.2% | 88,676 | 0.0% | 0.10% | +17.9% | |
| DOC | Physicians Realty Trust | $2,441,682 | -3.8% | 168,741 | 0.0% | 0.09% | -11.5% | |
| IDYA | IDEAYA Biosciences, Inc. | $2,419,971 | +21.8% | 133,185 | 0.0% | 0.09% | +12.3% | |
| CSII | Cardiovascular Systems, Inc. | $2,381,580 | -1.8% | 174,859 | 0.0% | 0.09% | -9.1% | |
| GTHX | G1 Therapeutics, Inc. | $2,301,609 | -56.5% | 423,869 | 0.0% | 0.09% | -59.9% | |
| CRSP | CRISPR Therapeutics AGnamen akt | $2,239,002 | -37.8% | 55,080 | 0.0% | 0.08% | -42.2% | |
| R1 RCM Inc. | $2,215,743 | -40.9% | 202,351 | 0.0% | 0.08% | -45.5% | ||
| ARQT | Arcutis Biotherapeutics, Inc. | $2,203,335 | -22.6% | 148,874 | 0.0% | 0.08% | -28.4% | |
| MEDP | Medpace Holdings, Inc. | $2,004,088 | +35.1% | 9,435 | 0.0% | 0.08% | +24.6% | |
| NTRA | Buy | Natera, Inc. | $1,979,256 | +111.0% | 49,272 | +130.2% | 0.08% | +97.4% |
| OPCH | Option Care Health, Inc. | $1,955,098 | -4.4% | 64,975 | 0.0% | 0.07% | -11.9% | |
| ICLR | Sell | Icon plcshares | $1,813,130 | -5.5% | 9,334 | -10.5% | 0.07% | -13.9% |
| ASRT | Assertio Holdings, Inc. | $1,765,473 | +89.4% | 410,575 | 0.0% | 0.07% | +76.3% | |
| EWTX | Edgewise Therapeutics, Inc. | $1,743,524 | -9.1% | 195,025 | 0.0% | 0.07% | -16.5% | |
| PRGO | Perrigo Company plcshares | $1,746,226 | -4.4% | 51,224 | 0.0% | 0.07% | -12.0% | |
| GMRE | Global Medical REIT Inc. | $1,658,024 | +11.3% | 174,897 | 0.0% | 0.06% | +3.3% | |
| PHG | Sell | Koninklijke Philips N.V.ny reg shares | $1,646,801 | -35.1% | 109,860 | -33.3% | 0.06% | -40.4% |
| TAK | Takeda Pharmaceutical Company Ltd.sponsored ads | $1,639,139 | +20.3% | 105,073 | 0.0% | 0.06% | +10.7% | |
| ARDX | Ardelyx, Inc. | $1,537,313 | +139.5% | 539,408 | 0.0% | 0.06% | +123.1% | |
| GSK plc ADRsponsored adr | $1,470,679 | +19.4% | 41,852 | 0.0% | 0.06% | +12.0% | ||
| ARVN | Sell | Arvinas, Inc. | $1,470,962 | -61.6% | 42,998 | -50.0% | 0.06% | -64.3% |
| MRUS | Sell | Merus N.V. | $1,428,268 | -57.9% | 92,325 | -45.4% | 0.05% | -61.2% |
| GRTX | Galera Therapeutics, Inc. | $1,338,577 | -14.4% | 898,374 | 0.0% | 0.05% | -20.3% | |
| ZLAB | Zai Lab Ltd.adr | $1,329,310 | -10.2% | 43,300 | 0.0% | 0.05% | -18.0% | |
| PTGX | New | Protagonist Therapeutics, Inc. | $1,333,977 | – | 122,271 | +100.0% | 0.05% | – |
| Stevanato Group Societa' Per Azioniordinary shares | $1,279,284 | +6.1% | 71,190 | 0.0% | 0.05% | -2.0% | ||
| MORF | Morphic Holding, Inc. | $1,193,719 | -5.5% | 44,625 | 0.0% | 0.04% | -13.5% | |
| STRO | Sell | Sutro Biopharma, Inc. | $1,192,050 | +31.0% | 147,531 | -10.0% | 0.04% | +21.6% |
| MREO | Mereo BioPharma Group plcads | $1,163,312 | -12.9% | 1,551,082 | 0.0% | 0.04% | -20.0% | |
| ACAD | ACADIA Pharmaceuticals Inc. | $1,149,822 | -2.7% | 72,225 | 0.0% | 0.04% | -10.4% | |
| SRRK | Scholar Rock Holding Corp. | $984,939 | +30.6% | 108,833 | 0.0% | 0.04% | +19.4% | |
| Pyxis Oncology, Inc. | $949,126 | -32.0% | 708,303 | 0.0% | 0.04% | -36.8% | ||
| CRNX | New | Crinetics Pharmaceuticals, Inc. | $839,256 | – | 45,861 | +100.0% | 0.03% | – |
| ALXO | ALX Oncology Holdings Inc. | $746,198 | +17.7% | 66,211 | 0.0% | 0.03% | +7.7% | |
| AFMD | Affimed N.V. | $726,687 | -39.8% | 586,038 | 0.0% | 0.03% | -44.9% | |
| PLRX | New | Pliant Therapeutics, Inc. | $681,054 | – | 35,233 | +100.0% | 0.03% | – |
| IMAB | I-Mabsponsored ads | $679,584 | +4.2% | 162,580 | 0.0% | 0.03% | -3.7% | |
| NVAX | Novavax, Inc. | $655,864 | -43.5% | 63,800 | 0.0% | 0.02% | -47.9% | |
| ICPT | Intercept Pharmaceuticals, Inc. | $644,069 | -11.3% | 52,067 | 0.0% | 0.02% | -20.0% | |
| BEAM | Beam Therapeutics Inc. | $618,603 | -18.0% | 15,817 | 0.0% | 0.02% | -25.8% | |
| NHI | National Health Investors, Inc. | $524,184 | -7.6% | 10,038 | 0.0% | 0.02% | -13.0% | |
| CHCT | Community Healthcare Trust Inc. | $533,420 | +9.3% | 14,900 | 0.0% | 0.02% | 0.0% | |
| ONEM | 1Life Healthcare, Inc. | $522,455 | -2.5% | 31,266 | 0.0% | 0.02% | -9.1% | |
| UHT | Universal Health Realty Income Trust | $537,344 | +10.6% | 11,258 | 0.0% | 0.02% | 0.0% | |
| Theseus Pharmaceuticals, Inc. | $498,000 | -14.1% | 100,000 | 0.0% | 0.02% | -20.8% | ||
| New | Biohaven Ltd. | $487,008 | – | 35,087 | +100.0% | 0.02% | – | |
| RPTX | Repare Therapeutics Inc. | $428,797 | +21.1% | 29,150 | 0.0% | 0.02% | +14.3% | |
| FULC | New | Fulcrum Therapeutics, Inc. | $426,149 | – | 58,537 | +100.0% | 0.02% | – |
| ACET | Adicet Bio, Inc. | $360,541 | -37.1% | 40,329 | 0.0% | 0.01% | -39.1% | |
| CYH | Community Health Systems, Inc. | $381,607 | +100.8% | 88,335 | 0.0% | 0.01% | +75.0% | |
| TScan Therapeutics, Inc. | $326,000 | -46.6% | 200,000 | 0.0% | 0.01% | -52.0% | ||
| CDXS | Codexis Inc | $322,123 | -23.1% | 69,125 | 0.0% | 0.01% | -29.4% | |
| MOR | MorphoSys AGsponsored ads | $293,084 | -28.9% | 81,867 | 0.0% | 0.01% | -35.3% | |
| DTIL | Precision BioSciences, Inc. | $267,195 | -8.5% | 224,534 | 0.0% | 0.01% | -16.7% | |
| New | Mallinckrodt plcshares | $271,622 | – | 35,048 | +100.0% | 0.01% | – | |
| DHC | Diversified Healthcare Trust | $231,373 | -34.6% | 357,720 | 0.0% | 0.01% | -35.7% | |
| BDTX | Black Diamond Therapeutics, Inc. | $237,582 | +6.5% | 131,990 | 0.0% | 0.01% | 0.0% | |
| PCVX | New | Vaxcyte, Inc. | $239,750 | – | 5,000 | +100.0% | 0.01% | – |
| HARP | Harpoon Therapeutics, Inc. | $188,617 | -25.2% | 259,910 | 0.0% | 0.01% | -30.0% | |
| PRAX | Praxis Precision Medicines, Inc. | $178,500 | +5.0% | 75,000 | 0.0% | 0.01% | 0.0% | |
| NKTX | Nkarta, Inc. | $173,638 | -54.4% | 28,988 | 0.0% | 0.01% | -56.2% | |
| FUSN | Sell | Fusion Pharmaceuticals Inc. | $136,691 | -77.4% | 43,394 | -57.4% | 0.01% | -80.0% |
| ABIO | ARCA biopharma, Inc. | $76,608 | +14.3% | 32,461 | 0.0% | 0.00% | 0.0% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $42,256 | -13.8% | 114,670 | 0.0% | 0.00% | 0.0% | |
| FVE | AlerisLife Inc. | $13,330 | -42.0% | 24,237 | 0.0% | 0.00% | 0.0% | |
| VYNE | VYNE Therapeutics Inc. | $20,309 | -32.3% | 135,395 | 0.0% | 0.00% | 0.0% | |
| CRBP | Corbus Pharmaceuticals Holdings, Inc. | $17,051 | -31.8% | 154,310 | 0.0% | 0.00% | 0.0% | |
| NexGel, Inc. | $5,304 | -11.6% | 4,243 | 0.0% | 0.00% | – | ||
| Bellicum Pharmaceuticals, Inc. | $4,320 | -38.3% | 6,000 | 0.0% | 0.00% | – | ||
| ENDP | Exit | Endo International plcshares | $0 | – | -494,607 | -100.0% | -0.00% | – |
| Exit | Terumo Corp. | $0 | – | -17,288 | -100.0% | -0.02% | – | |
| Exit | Protagonist Therapeutics, Inc. | $0 | – | -122,271 | -100.0% | -0.04% | – | |
| RNA | Exit | Avidity Biosciences, Inc. | $0 | – | -64,618 | -100.0% | -0.04% | – |
| XLV | Exit | Health Care Select Sector SPDR Fundsbi healthcare | $0 | – | -29,024 | -100.0% | -0.14% | – |
| CCXI | Exit | ChemoCentryx, Inc. | $0 | – | -78,197 | -100.0% | -0.16% | – |
| DSGN | Exit | Design Therapeutics, Inc. | $0 | – | -280,523 | -100.0% | -0.19% | – |
| OMI | Exit | Owens & Minor, Inc. | $0 | – | -225,117 | -100.0% | -0.22% | – |
| BHVN | Exit | Biohaven Pharmaceutical Holding Company Ltd. | $0 | – | -70,176 | -100.0% | -0.43% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-02-10
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.