$2.63 Billion is the total value of Tekla Capital Management LLC's 177 reported holdings in Q1 2023. The portfolio turnover from Q4 2022 to Q1 2023 was 20.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AMGN | Buy | Amgen Inc. | $134,398,253 | +0.6% | 555,939 | +9.3% | 5.12% | +1.4% |
| GILD | Buy | Gilead Sciences, Inc. | $129,423,575 | -0.2% | 1,559,884 | +3.3% | 4.93% | +0.6% |
| REGN | Buy | Regeneron Pharmaceuticals, Inc. | $117,542,359 | +34.8% | 143,053 | +18.4% | 4.48% | +35.9% |
| JNJ | Buy | Johnson & Johnson | $111,875,745 | -1.0% | 721,779 | +12.8% | 4.26% | -0.2% |
| UNH | Sell | Unitedhealth Group Inc. | $110,667,818 | -22.8% | 234,173 | -13.4% | 4.21% | -22.2% |
| VRTX | Vertex Pharmaceuticals Inc. | $104,081,169 | +9.1% | 330,343 | 0.0% | 3.96% | +10.0% | |
| LLY | Eli Lilly and Company | $99,219,876 | -6.1% | 288,917 | 0.0% | 3.78% | -5.4% | |
| ABBV | Buy | AbbVie Inc. | $81,533,533 | +5.5% | 511,599 | +7.0% | 3.10% | +6.3% |
| ILMN | Buy | Illumina, Inc. | $80,945,771 | +25.1% | 348,079 | +8.8% | 3.08% | +26.2% |
| PFE | Buy | Pfizer Inc. | $72,423,101 | -3.0% | 1,775,076 | +21.8% | 2.76% | -2.2% |
| AZN | Sell | AstraZeneca PLCsponsored adr | $68,900,808 | -0.6% | 992,664 | -2.9% | 2.62% | +0.2% |
| BIIB | Buy | Biogen Inc. | $66,984,656 | +23.8% | 240,926 | +23.3% | 2.55% | +24.8% |
| ABT | Sell | Abbott Laboratories | $63,171,557 | -17.0% | 623,855 | -10.0% | 2.40% | -16.3% |
| MRK | Merck & Co., Inc. | $58,740,260 | -4.1% | 552,122 | 0.0% | 2.24% | -3.4% | |
| TMO | Thermo Fisher Scientific Inc. | $54,008,751 | +4.7% | 93,705 | 0.0% | 2.06% | +5.5% | |
| ANTM | Buy | Elevance Health, Inc. | $52,450,527 | +598.2% | 114,070 | +679.0% | 2.00% | +603.2% |
| MRNA | Buy | Moderna, Inc. | $49,486,087 | +4.0% | 322,217 | +21.6% | 1.88% | +4.8% |
| CI | The Cigna Group | $46,667,699 | -22.9% | 182,631 | 0.0% | 1.78% | -22.2% | |
| BMY | Sell | Bristol-Myers Squibb Company | $46,007,701 | -7.0% | 663,796 | -3.5% | 1.75% | -6.2% |
| SGEN | Buy | Seagen Inc. | $45,487,518 | +215.4% | 224,663 | +100.2% | 1.73% | +217.8% |
| SRPT | Buy | Sarepta Therapeutics, Inc. | $39,371,553 | +115.6% | 285,653 | +102.6% | 1.50% | +117.2% |
| ARGX | Buy | argenx SEsponsored adr | $32,902,540 | +3.4% | 88,310 | +5.1% | 1.25% | +4.2% |
| IDXX | Sell | IDEXX Laboratories, Inc. | $29,302,188 | +5.5% | 58,595 | -13.9% | 1.12% | +6.4% |
| BMRN | Buy | BioMarin Pharmaceutical Inc. | $29,180,654 | +22.2% | 300,089 | +30.0% | 1.11% | +23.2% |
| ISRG | Intuitive Surgical, Inc. | $28,786,360 | -3.7% | 112,680 | 0.0% | 1.10% | -2.9% | |
| ALNY | Alnylam Pharmaceuticals, Inc. | $28,688,628 | -15.7% | 143,214 | 0.0% | 1.09% | -15.0% | |
| BSX | Sell | Boston Scientific Corp. | $28,316,480 | -19.2% | 565,990 | -25.2% | 1.08% | -18.5% |
| MDT | Buy | Medtronic plcshares | $27,774,961 | +9.6% | 344,517 | +5.6% | 1.06% | +10.4% |
| DHR | Danaher Corp. | $26,638,108 | -5.0% | 105,690 | 0.0% | 1.01% | -4.2% | |
| DXCM | Buy | Dexcom, Inc. | $26,575,826 | +7.6% | 228,747 | +4.9% | 1.01% | +8.6% |
| CRL | Buy | Charles River Laboratories International, Inc. | $23,831,511 | +50.5% | 118,083 | +62.5% | 0.91% | +51.7% |
| MCK | McKesson Corp. | $23,661,303 | -5.1% | 66,455 | 0.0% | 0.90% | -4.3% | |
| HCA | Sell | HCA Healthcare, Inc. | $23,389,207 | -7.2% | 88,703 | -15.5% | 0.89% | -6.5% |
| ZTS | Zoetis Inc.class a | $22,787,966 | +13.6% | 136,914 | 0.0% | 0.87% | +14.5% | |
| JAZZ | Sell | Jazz Pharmaceuticals plcshares | $21,624,501 | -25.7% | 147,779 | -19.2% | 0.82% | -25.2% |
| SYK | Sell | Stryker Corp. | $20,433,372 | -49.1% | 71,578 | -56.4% | 0.78% | -48.6% |
| HUM | Sell | Humana Inc. | $17,862,015 | -55.1% | 36,794 | -52.7% | 0.68% | -54.8% |
| NVO | Sell | Novo Nordisk A/Ssponsored adr | $17,715,942 | +0.3% | 111,323 | -14.7% | 0.67% | +1.0% |
| MOH | Sell | Molina Healthcare, Inc. | $16,545,861 | -31.9% | 61,856 | -16.0% | 0.63% | -31.4% |
| RMD | Buy | ResMed Inc. | $16,027,659 | +26.9% | 73,189 | +20.6% | 0.61% | +27.9% |
| EW | Sell | Edwards Lifesciences Corp. | $14,158,909 | +10.7% | 171,146 | -0.1% | 0.54% | +11.6% |
| EXEL | New | Exelixis, Inc. | $14,104,063 | – | 726,639 | +100.0% | 0.54% | – |
| UTHR | Sell | United Therapeutics Corp. | $13,706,352 | -57.2% | 61,200 | -46.8% | 0.52% | -56.8% |
| ACHC | Buy | Acadia Healthcare Company, Inc. | $13,473,686 | +15.9% | 186,487 | +32.1% | 0.51% | +16.9% |
| ASND | Ascendis Pharma A/Ssponsored adr | $13,272,871 | -12.2% | 123,791 | 0.0% | 0.50% | -11.6% | |
| QURE | uniQure N.V.shares | $13,140,262 | -11.2% | 652,446 | 0.0% | 0.50% | -10.6% | |
| DOC | Buy | Physicians Realty Trust | $13,043,669 | +434.2% | 873,655 | +417.7% | 0.50% | +440.2% |
| BNTX | BioNTech SEsponsored ads | $12,937,591 | -17.1% | 103,858 | 0.0% | 0.49% | -16.3% | |
| IQV | IQVIA Holdings Inc. | $12,553,340 | -2.9% | 63,117 | 0.0% | 0.48% | -2.0% | |
| NVS | Novartis AGsponsored adr | $12,532,700 | +1.4% | 136,225 | 0.0% | 0.48% | +2.1% | |
| NBIX | Neurocrine Biosciences, Inc. | $11,428,548 | -15.3% | 112,908 | 0.0% | 0.44% | -14.5% | |
| XBI | SPDR S&P Biotech ETFs&p biotech etf | $11,254,464 | -8.2% | 147,677 | 0.0% | 0.43% | -7.6% | |
| GH | Guardant Health, Inc. | $11,067,993 | -13.8% | 472,184 | 0.0% | 0.42% | -13.2% | |
| New | Oculis Holding AG | $11,047,302 | – | 1,690,741 | +100.0% | 0.42% | – | |
| Rallybio Corporation | $9,861,553 | -13.1% | 1,727,067 | 0.0% | 0.38% | -12.6% | ||
| AVTR | Avantor, Inc. | $9,713,576 | +0.2% | 459,488 | 0.0% | 0.37% | +1.1% | |
| KRTX | Karuna Therapeutics, Inc. | $9,709,021 | -7.6% | 53,452 | 0.0% | 0.37% | -6.8% | |
| TVTX | Travere Therapeutics, Inc. | $9,412,515 | +6.9% | 418,520 | 0.0% | 0.36% | +7.8% | |
| ITCI | Intra-Cellular Therapies, Inc. | $9,333,890 | +2.3% | 172,371 | 0.0% | 0.36% | +2.9% | |
| LH | Sell | Laboratory Corporation of America Holdings | $9,186,436 | -11.6% | 40,042 | -9.3% | 0.35% | -10.9% |
| APLS | Buy | Apellis Pharmaceuticals, Inc. | $8,912,779 | +159.5% | 135,124 | +103.4% | 0.34% | +160.8% |
| ALKS | Alkermes plcshares | $8,727,990 | +7.9% | 309,613 | 0.0% | 0.33% | +8.5% | |
| ZBH | Sell | Zimmer Biomet Holdings, Inc. | $8,702,395 | -73.6% | 67,356 | -74.0% | 0.33% | -73.5% |
| OHI | Omega Healthcare Investors, Inc. | $8,399,329 | -1.9% | 306,433 | 0.0% | 0.32% | -0.9% | |
| CYTK | Buy | Cytokinetics, Inc. | $7,707,490 | +123.9% | 219,025 | +191.5% | 0.29% | +125.4% |
| DNLI | Buy | Denali Therapeutics, Inc. | $7,484,060 | -1.2% | 324,829 | +19.2% | 0.28% | -0.3% |
| CVS | CVS Health Corp. | $6,956,977 | -20.3% | 93,621 | 0.0% | 0.26% | -19.5% | |
| SNY | Sanofisponsored adr | $6,718,367 | +12.4% | 123,454 | 0.0% | 0.26% | +13.3% | |
| LNTH | Sell | Lantheus Holdings, Inc. | $6,563,107 | -62.4% | 79,495 | -76.8% | 0.25% | -62.1% |
| LTC | LTC Properties, Inc. | $6,403,953 | -1.1% | 182,293 | 0.0% | 0.24% | -0.4% | |
| A | Agilent Technologies, Inc. | $5,975,043 | -7.6% | 43,191 | 0.0% | 0.23% | -7.0% | |
| STE | Buy | STERIS plcshares | $5,943,452 | +93.1% | 31,072 | +86.4% | 0.23% | +94.8% |
| VECT | Sell | VectivBio Holding AG | $5,872,372 | -7.5% | 682,834 | -7.4% | 0.22% | -6.7% |
| SBRA | Sabra Health Care REIT, Inc. | $5,872,590 | -7.5% | 510,660 | 0.0% | 0.22% | -6.7% | |
| NTLA | Intellia Therapeutics, Inc. | $5,749,606 | +6.8% | 154,269 | 0.0% | 0.22% | +7.9% | |
| MDRX | Veradigm, Inc. | $5,592,969 | -26.0% | 428,580 | 0.0% | 0.21% | -25.5% | |
| RXDX | Buy | Prometheus Biosciences, Inc. | $5,423,738 | +29.0% | 50,538 | +32.2% | 0.21% | +29.6% |
| Buy | R1 RCM Inc. | $5,352,765 | +141.6% | 356,851 | +76.4% | 0.20% | +142.9% | |
| WST | New | West Pharmaceutical Services, Inc. | $5,209,523 | – | 15,036 | +100.0% | 0.20% | – |
| AMED | New | Amedisys, Inc. | $5,071,199 | – | 68,949 | +100.0% | 0.19% | – |
| SNN | Smith & Nephew plcsponsored adr | $5,071,526 | +3.8% | 181,710 | 0.0% | 0.19% | +4.3% | |
| ADUS | Addus HomeCare Corp. | $4,524,489 | +7.3% | 42,380 | 0.0% | 0.17% | +8.2% | |
| BGNE | BeiGene, Ltd.sponsored adr | $4,515,785 | -2.0% | 20,952 | 0.0% | 0.17% | -1.1% | |
| CERE | Cerevel Therapeutics Holdings, Inc. | $4,304,420 | -22.7% | 176,483 | 0.0% | 0.16% | -21.9% | |
| BCRX | Sell | BioCryst Pharmaceuticals, Inc. | $4,207,764 | -45.5% | 504,528 | -25.0% | 0.16% | -45.2% |
| TEVA | Teva Pharmaceutical Industries Ltd.sponsored adr | $4,067,911 | -3.0% | 459,651 | 0.0% | 0.16% | -1.9% | |
| ADPT | Adaptive Biotechnologies Corp. | $3,728,741 | +15.6% | 422,281 | 0.0% | 0.14% | +16.4% | |
| KURA | Kura Oncology, Inc. | $3,464,527 | -1.5% | 283,281 | 0.0% | 0.13% | -0.8% | |
| CSII | Cardiovascular Systems, Inc. | $3,472,700 | +45.8% | 174,859 | 0.0% | 0.13% | +46.7% | |
| MPW | Medical Properties Trust, Inc. | $3,384,527 | -26.2% | 411,743 | 0.0% | 0.13% | -25.4% | |
| Healthcare Realty Trust Inc. | $3,376,680 | +0.3% | 174,686 | 0.0% | 0.13% | +1.6% | ||
| PEAK | Healthpeak Properties, Inc. | $3,304,112 | -12.4% | 150,392 | 0.0% | 0.13% | -11.3% | |
| CTLT | Sell | Catalent, Inc. | $3,246,468 | -42.7% | 49,406 | -60.8% | 0.12% | -42.1% |
| ABC | Amerisourcebergen Corp. | $3,268,966 | -3.4% | 20,417 | 0.0% | 0.12% | -3.1% | |
| IBB | Ishares Biothechnology ETF | $3,173,332 | -1.6% | 24,569 | 0.0% | 0.12% | -0.8% | |
| New | Marinus Pharmaceuticals, Inc. | $3,151,782 | – | 456,780 | +100.0% | 0.12% | – | |
| IONS | Ionis Pharmaceuticals, Inc. | $3,139,402 | -5.4% | 87,840 | 0.0% | 0.12% | -4.0% | |
| BPMC | Blueprint Medicines Corp. | $3,046,273 | +2.7% | 67,710 | 0.0% | 0.12% | +3.6% | |
| MDGL | New | Madrigal Pharmaceuticals, Inc. | $3,023,647 | – | 12,481 | +100.0% | 0.12% | – |
| Caribou Biosciences, Inc. | $3,011,551 | -15.4% | 567,147 | 0.0% | 0.12% | -14.8% | ||
| XENE | Xenon Pharmaceuticals Inc. | $2,996,124 | -9.2% | 83,714 | 0.0% | 0.11% | -8.8% | |
| WELL | Welltower Inc. | $2,973,988 | +9.4% | 41,484 | 0.0% | 0.11% | +9.7% | |
| VTR | Ventas, Inc. | $2,890,621 | -3.8% | 66,681 | 0.0% | 0.11% | -2.7% | |
| Pyxis Oncology, Inc. | $2,840,295 | +199.3% | 708,303 | 0.0% | 0.11% | +200.0% | ||
| LIVN | New | LivaNova plc | $2,783,890 | – | 63,880 | +100.0% | 0.11% | – |
| NTRA | Natera, Inc. | $2,735,581 | +38.2% | 49,272 | 0.0% | 0.10% | +38.7% | |
| BAX | New | Baxter International, Inc. | $2,730,175 | – | 67,312 | +100.0% | 0.10% | – |
| RARE | Ultragenyx Pharmaceutical Inc. | $2,689,307 | -13.4% | 67,065 | 0.0% | 0.10% | -12.8% | |
| ASRT | Assertio Holdings, Inc. | $2,615,363 | +48.1% | 410,575 | 0.0% | 0.10% | +49.3% | |
| ARDX | Ardelyx, Inc. | $2,583,764 | +68.1% | 539,408 | 0.0% | 0.10% | +69.0% | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | $2,550,719 | -37.4% | 100,422 | 0.0% | 0.10% | -37.0% | |
| BBIO | New | Bridgebio Pharma, Inc. | $2,502,270 | – | 150,921 | +100.0% | 0.10% | – |
| CRSP | CRISPR Therapeutics AGnamen akt | $2,491,268 | +11.3% | 55,080 | 0.0% | 0.10% | +11.8% | |
| SNDX | Syndax Pharmaceuticals, Inc. | $2,486,183 | -17.0% | 117,717 | 0.0% | 0.10% | -15.9% | |
| MRTX | Mirati Therapeutics, Inc. | $2,434,918 | -17.9% | 65,490 | 0.0% | 0.09% | -17.0% | |
| ALGN | Sell | Align Technology, Inc. | $2,313,920 | -78.4% | 6,925 | -86.4% | 0.09% | -78.3% |
| GRTX | Galera Therapeutics, Inc. | $2,299,837 | +71.8% | 898,374 | 0.0% | 0.09% | +72.5% | |
| OPCH | Option Care Health, Inc. | $2,064,256 | +5.6% | 64,975 | 0.0% | 0.08% | +6.8% | |
| PHG | Koninklijke Philips N.V.ny reg shares | $2,015,931 | +22.4% | 109,860 | 0.0% | 0.08% | +24.2% | |
| ICLR | Icon plcshares | $1,993,649 | +10.0% | 9,334 | 0.0% | 0.08% | +11.8% | |
| KDNY | New | Chinook Therapeutics, Inc. | $1,933,025 | – | 83,500 | +100.0% | 0.07% | – |
| BCYC | Bicycle Therapeutics PLCsponsored ads | $1,886,139 | -28.1% | 88,676 | 0.0% | 0.07% | -27.3% | |
| PRGO | Perrigo Company plcshares | $1,837,405 | +5.2% | 51,224 | 0.0% | 0.07% | +6.1% | |
| MEDP | Medpace Holdings, Inc. | $1,774,252 | -11.5% | 9,435 | 0.0% | 0.07% | -10.5% | |
| IMVT | New | Immunovant, Inc. | $1,789,854 | – | 115,400 | +100.0% | 0.07% | – |
| TAK | Takeda Pharmaceutical Company Ltd.sponsored ads | $1,731,603 | +5.6% | 105,073 | 0.0% | 0.07% | +6.5% | |
| ARQT | Arcutis Biotherapeutics, Inc. | $1,637,614 | -25.7% | 148,874 | 0.0% | 0.06% | -25.3% | |
| RETA | New | Reata Pharmaceuticals, Inc. Class Aclass a | $1,622,922 | – | 17,850 | +100.0% | 0.06% | – |
| ETNB | New | 89bio, Inc. | $1,612,827 | – | 105,898 | +100.0% | 0.06% | – |
| GMRE | Global Medical REIT Inc. | $1,593,312 | -3.9% | 174,897 | 0.0% | 0.06% | -3.2% | |
| GSK plcsponsored adr | $1,489,094 | +1.3% | 41,852 | 0.0% | 0.06% | +1.8% | ||
| EWTX | Edgewise Therapeutics, Inc. | $1,300,817 | -25.4% | 195,025 | 0.0% | 0.05% | -24.2% | |
| MRUS | Sell | Merus N.V. | $1,270,060 | -11.1% | 69,025 | -25.2% | 0.05% | -11.1% |
| CRNX | Buy | Crinetics Pharmaceuticals, Inc. | $1,261,176 | +50.3% | 78,529 | +71.2% | 0.05% | +50.0% |
| ZLAB | Sell | Zai Lab Ltd.adr | $1,152,126 | -13.3% | 34,640 | -20.0% | 0.04% | -12.0% |
| GTHX | G1 Therapeutics, Inc. | $1,135,969 | -50.6% | 423,869 | 0.0% | 0.04% | -50.6% | |
| MREO | Mereo BioPharma Group plcads | $1,096,460 | -5.7% | 1,551,082 | 0.0% | 0.04% | -4.5% | |
| SRRK | Scholar Rock Holding Corp. | $870,664 | -11.6% | 108,833 | 0.0% | 0.03% | -10.8% | |
| ICPT | Intercept Pharmaceuticals, Inc. | $699,260 | +8.6% | 52,067 | 0.0% | 0.03% | +12.5% | |
| MRSN | New | Mersana Therapeutics, Inc. | $667,394 | – | 162,383 | +100.0% | 0.02% | – |
| Sell | Theseus Pharmaceuticals, Inc. | $666,000 | +33.7% | 75,000 | -25.0% | 0.02% | +31.6% | |
| ITOS | New | iTeos Therapeutics, Inc. | $622,453 | – | 45,735 | +100.0% | 0.02% | – |
| RCUS | New | Arcus Biosciences, Inc. | $598,983 | – | 32,839 | +100.0% | 0.02% | – |
| TCMD | New | Tactile Systems Technology, Inc. | $565,373 | – | 34,432 | +100.0% | 0.02% | – |
| UHT | Universal Health Realty Income Trust | $541,622 | +0.8% | 11,258 | 0.0% | 0.02% | +5.0% | |
| IMAB | I-Mabsponsored ads | $562,527 | -17.2% | 162,580 | 0.0% | 0.02% | -19.2% | |
| CHCT | Community Healthcare Trust Inc. | $545,340 | +2.2% | 14,900 | 0.0% | 0.02% | +5.0% | |
| NHI | National Health Investors, Inc. | $517,760 | -1.2% | 10,038 | 0.0% | 0.02% | 0.0% | |
| DHC | Diversified Healthcare Trust | $482,922 | +108.7% | 357,720 | 0.0% | 0.02% | +100.0% | |
| BEAM | Beam Therapeutics Inc. | $484,317 | -21.7% | 15,817 | 0.0% | 0.02% | -21.7% | |
| Biohaven Ltd. | $479,288 | -1.6% | 35,087 | 0.0% | 0.02% | 0.0% | ||
| NVAX | Novavax, Inc. | $442,134 | -32.6% | 63,800 | 0.0% | 0.02% | -32.0% | |
| STRO | Sell | Sutro Biopharma, Inc. | $454,395 | -61.9% | 98,354 | -33.3% | 0.02% | -62.2% |
| AFMD | Affimed N.V. | $436,950 | -39.9% | 586,038 | 0.0% | 0.02% | -37.0% | |
| TScan Therapeutics, Inc. | $420,000 | +28.8% | 200,000 | 0.0% | 0.02% | +33.3% | ||
| CYH | Community Health Systems, Inc. | $432,842 | +13.4% | 88,335 | 0.0% | 0.02% | +14.3% | |
| ALT | New | Altimmune, Inc. | $316,500 | – | 75,000 | +100.0% | 0.01% | – |
| MOR | MorphoSys AGsponsored ads | $323,375 | +10.3% | 81,867 | 0.0% | 0.01% | +9.1% | |
| CDXS | Codexis Inc | $286,178 | -11.2% | 69,125 | 0.0% | 0.01% | -8.3% | |
| RPTX | Repare Therapeutics Inc. | $286,836 | -33.1% | 29,150 | 0.0% | 0.01% | -31.2% | |
| ALXO | ALX Oncology Holdings Inc. | $299,274 | -59.9% | 66,211 | 0.0% | 0.01% | -60.7% | |
| Mallinckrodt plcshares | $255,503 | -5.9% | 35,048 | 0.0% | 0.01% | 0.0% | ||
| ACET | Adicet Bio, Inc. | $232,295 | -35.6% | 40,329 | 0.0% | 0.01% | -35.7% | |
| BDTX | Black Diamond Therapeutics, Inc. | $249,461 | +5.0% | 131,990 | 0.0% | 0.01% | 0.0% | |
| HARP | Harpoon Therapeutics, Inc. | $193,425 | +2.5% | 259,910 | 0.0% | 0.01% | 0.0% | |
| PCVX | Vaxcyte, Inc. | $187,400 | -21.8% | 5,000 | 0.0% | 0.01% | -22.2% | |
| DTIL | Precision BioSciences, Inc. | $169,209 | -36.7% | 224,534 | 0.0% | 0.01% | -40.0% | |
| FUSN | Fusion Pharmaceuticals Inc. | $163,595 | +19.7% | 43,394 | 0.0% | 0.01% | +20.0% | |
| FULC | Fulcrum Therapeutics, Inc. | $166,830 | -60.9% | 58,537 | 0.0% | 0.01% | -62.5% | |
| NKTX | Nkarta, Inc. | $102,907 | -40.7% | 28,988 | 0.0% | 0.00% | -42.9% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $86,003 | +103.5% | 114,670 | 0.0% | 0.00% | +50.0% | |
| PRAX | Praxis Precision Medicines, Inc. | $60,675 | -66.0% | 75,000 | 0.0% | 0.00% | -71.4% | |
| ABIO | ARCA biopharma, Inc. | $64,597 | -15.7% | 32,461 | 0.0% | 0.00% | -33.3% | |
| New | VYNE Therapeutics, Inc. | $23,162 | – | 7,520 | +100.0% | 0.00% | – | |
| New | Corbus Pharmaceuticals Holdings, Inc. | $37,390 | – | 5,143 | +100.0% | 0.00% | – | |
| NexGel, Inc. | $5,516 | +4.0% | 4,243 | 0.0% | 0.00% | – | ||
| Bellicum Pharmaceuticals, Inc. | $1,980 | -54.2% | 6,000 | 0.0% | 0.00% | – | ||
| VYNE | Exit | VYNE Therapeutics Inc. | $0 | – | -135,395 | -100.0% | -0.00% | – |
| FVE | Exit | AlerisLife Inc. | $0 | – | -24,237 | -100.0% | -0.00% | – |
| CRBP | Exit | Corbus Pharmaceuticals Holdings, Inc. | $0 | – | -154,310 | -100.0% | -0.00% | – |
| ONEM | Exit | 1Life Healthcare, Inc. | $0 | – | -31,266 | -100.0% | -0.02% | – |
| PLRX | Exit | Pliant Therapeutics, Inc. | $0 | – | -35,233 | -100.0% | -0.03% | – |
| ACAD | Exit | ACADIA Pharmaceuticals Inc. | $0 | – | -72,225 | -100.0% | -0.04% | – |
| MORF | Exit | Morphic Holding, Inc. | $0 | – | -44,625 | -100.0% | -0.04% | – |
| Exit | Stevanato Group Societa' Per Azioniordinary shares | $0 | – | -71,190 | -100.0% | -0.05% | – | |
| PTGX | Exit | Protagonist Therapeutics, Inc. | $0 | – | -122,271 | -100.0% | -0.05% | – |
| ARVN | Exit | Arvinas, Inc. | $0 | – | -42,998 | -100.0% | -0.06% | – |
| IDYA | Exit | IDEAYA Biosciences, Inc. | $0 | – | -133,185 | -100.0% | -0.09% | – |
| Exit | MoonLake Immunotherapeutics AG | $0 | – | -300,000 | -100.0% | -0.12% | – | |
| XNCR | Exit | Xencor, Inc. | $0 | – | -200,328 | -100.0% | -0.20% | – |
| HQY | Exit | HealthEquity, Inc. | $0 | – | -110,214 | -100.0% | -0.26% | – |
| HZNP | Exit | Horizon Therapeutics plc | $0 | – | -415,053 | -100.0% | -1.78% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2023-05-10
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.