Tekla Capital Management LLC - Q1 2022 holdings

$2.85 Billion is the total value of Tekla Capital Management LLC's 175 reported holdings in Q1 2022. The portfolio turnover from Q4 2021 to Q1 2022 was 14.0% .

 Value Shares↓ Weighting
UNH BuyUnitedhealth Group Inc.$168,303,000
+4.6%
330,026
+3.0%
5.91%
+14.2%
AMGN  Amgen Inc.$139,027,000
+7.5%
574,9180.0%4.88%
+17.3%
REGN BuyRegeneron Pharmaceuticals, Inc.$102,109,000
+13.0%
146,200
+2.2%
3.59%
+23.4%
HZNP BuyHorizon Therapeutics plcshares$100,943,000
+4.4%
959,439
+6.9%
3.54%
+13.9%
GILD  Gilead Sciences, Inc.$100,266,000
-18.1%
1,686,5650.0%3.52%
-10.6%
JNJ  Johnson & Johnson$91,566,000
+3.6%
516,6520.0%3.22%
+13.1%
ABBV BuyAbbVie Inc.$88,860,000
+28.7%
548,144
+7.5%
3.12%
+40.5%
VRTX BuyVertex Pharmaceuticals Inc.$80,609,000
+34.4%
308,884
+13.1%
2.83%
+46.8%
ILMN  Illumina, Inc.$79,038,000
-8.2%
226,2120.0%2.78%
+0.3%
ABT BuyAbbott Laboratories$73,238,000
-10.8%
618,777
+6.1%
2.57%
-2.6%
AZN BuyAstraZeneca PLCsponsored adr$65,721,000
+43.3%
990,675
+25.8%
2.31%
+56.4%
MCK BuyMcKesson Corp.$63,070,000
+34.6%
206,022
+9.3%
2.22%
+46.9%
PFE  Pfizer Inc.$60,669,000
-12.3%
1,171,9030.0%2.13%
-4.3%
LLY SellEli Lilly and Company$60,662,000
-4.7%
211,832
-8.1%
2.13%
+4.0%
SYK BuyStryker Corp.$60,335,000
+22.9%
225,678
+22.9%
2.12%
+34.1%
TMO SellThermo Fisher Scientific Inc.$57,650,000
-43.3%
97,605
-35.9%
2.02%
-38.1%
MRNA SellModerna, Inc.$56,592,000
-59.2%
328,524
-39.9%
1.99%
-55.5%
BMY SellBristol-Myers Squibb Company$52,865,000
+13.5%
723,876
-3.1%
1.86%
+23.9%
MDT SellMedtronic plcshares$48,279,000
-7.7%
435,140
-14.0%
1.70%
+0.7%
SGEN SellSeagen Inc.$47,617,000
-22.9%
330,561
-17.3%
1.67%
-15.9%
MRK SellMerck & Co., Inc.$47,230,000
-21.8%
575,622
-27.0%
1.66%
-14.7%
DHR SellDanaher Corp.$44,042,000
-33.8%
150,145
-25.8%
1.55%
-27.8%
CI BuyCigna Corp.$41,218,000
+25.2%
172,023
+19.9%
1.45%
+36.6%
IDXX SellIDEXX Laboratories, Inc.$33,489,000
-36.2%
61,217
-23.2%
1.18%
-30.3%
MOH SellMolina Healthcare, Inc.$31,533,000
+0.8%
94,525
-3.9%
1.11%
+10.0%
HCA BuyHCA Healthcare, Inc.$31,153,000
+8.3%
124,303
+11.0%
1.09%
+18.1%
SYNH SellSyneos Health, Inc.class a$30,888,000
-25.4%
381,570
-5.3%
1.08%
-18.5%
BIIB  Biogen Inc.$28,566,000
-12.2%
135,6390.0%1.00%
-4.2%
HUM SellHumana Inc.$27,659,000
-14.4%
63,560
-8.8%
0.97%
-6.6%
ZTS BuyZoetis Inc.class a$26,623,000
-10.9%
141,167
+15.2%
0.94%
-2.8%
ALNY SellAlnylam Pharmaceuticals, Inc.$25,899,000
-19.5%
158,606
-16.4%
0.91%
-12.1%
BSX BuyBoston Scientific Corp.$25,219,000
+10.8%
569,398
+6.2%
0.89%
+20.9%
GH  Guardant Health, Inc.$23,282,000
-33.8%
351,4840.0%0.82%
-27.7%
IQV  IQVIA Holdings Inc.$22,694,000
-18.1%
98,1540.0%0.80%
-10.5%
JAZZ BuyJazz Pharmaceuticals plcshares$21,867,000
+46.3%
140,473
+19.7%
0.77%
+59.7%
ICLR SellIcon plcshares$21,461,000
-29.9%
88,237
-10.8%
0.75%
-23.5%
EW  Edwards Lifesciences Corp.$20,859,000
-9.1%
177,1880.0%0.73%
-0.8%
BDX BuyBecton, Dickinson and Company$19,665,000
+80.6%
73,930
+70.7%
0.69%
+97.4%
WELL  Welltower Inc.$19,524,000
+12.1%
203,0830.0%0.69%
+22.5%
DXCM SellDexcom, Inc.$18,761,000
-16.7%
36,671
-12.5%
0.66%
-9.0%
ZBH  Zimmer Biomet Holdings, Inc.$18,167,000
+0.7%
142,0440.0%0.64%
+9.8%
SRPT SellSarepta Therapeutics, Inc.$17,788,000
-37.5%
227,697
-27.9%
0.62%
-31.7%
ITCI BuyIntra-Cellular Therapies, Inc.$17,802,000
+43.8%
290,936
+23.0%
0.62%
+57.0%
CRL  Charles River Laboratories International, Inc.$17,603,000
-24.6%
61,9900.0%0.62%
-17.8%
ISRG  Intuitive Surgical, Inc.$17,379,000
-16.0%
57,6060.0%0.61%
-8.4%
RMD SellResMed Inc.$17,218,000
-11.4%
70,999
-4.8%
0.60%
-3.2%
NVO BuyNovo Nordisk A/Ssponsored adr$17,049,000
+28.6%
153,523
+29.7%
0.60%
+40.3%
BNTX BuyBioNTech SEsponsored ads$16,210,000
-30.3%
95,042
+5.3%
0.57%
-24.0%
XLV  Health Care Select Sector SPDR Fundsbi healthcare$15,511,000
-2.8%
113,2300.0%0.54%
+6.2%
SellRallybio Corp.$15,321,000
-24.9%
2,195,010
-4.9%
0.54%
-18.1%
VTR  Ventas, Inc.$15,325,000
+20.8%
248,1310.0%0.54%
+31.9%
CVS  CVS Health Corp.$14,924,000
-1.9%
147,4530.0%0.52%
+7.2%
UTHR SellUnited Therapeutics Corp.$12,954,000
-41.1%
72,206
-29.0%
0.46%
-35.6%
KRTX  Karuna Therapeutics, Inc.$12,737,000
-3.2%
100,4580.0%0.45%
+5.7%
OMI  Owens & Minor, Inc.$12,685,000
+1.2%
288,1670.0%0.44%
+10.4%
ARGX  argenx SEsponsored adr$12,126,000
-10.0%
38,4560.0%0.43%
-1.6%
NVS  Novartis AGsponsored adr$11,954,000
+0.3%
136,2250.0%0.42%
+9.7%
NBIX  Neurocrine Biosciences, Inc.$11,682,000
+10.1%
124,6090.0%0.41%
+20.2%
LH  Laboratory Corporation of America Holdingssponsored adr$11,638,000
-16.1%
44,1420.0%0.41%
-8.3%
RARE  Ultragenyx Pharmaceutical Inc.$10,220,000
-13.6%
140,7260.0%0.36%
-5.8%
APLS  Apellis Pharmaceuticals, Inc.$9,950,000
+7.5%
195,8200.0%0.35%
+17.1%
BMRN  BioMarin Pharmaceutical Inc.$9,869,000
-12.7%
128,0040.0%0.35%
-4.7%
BGNE SellBeiGene, Ltd.sponsored adr$9,622,000
-44.3%
51,018
-20.0%
0.34%
-39.2%
OHI  Omega Healthcare Investors, Inc.$9,548,000
+5.3%
306,4330.0%0.34%
+14.7%
QURE  uniQure N.V.shares$9,427,000
-12.9%
521,6930.0%0.33%
-4.9%
A BuyAgilent Technologies, Inc.$8,846,000
+39.8%
66,845
+68.7%
0.31%
+52.5%
WAT  Waters Corp.$8,834,000
-16.7%
28,4610.0%0.31%
-9.1%
MPW  Medical Properties Trust, Inc.$8,704,000
-10.5%
411,7430.0%0.31%
-2.2%
DOC  Physicians Realty Trust$8,695,000
-6.9%
495,7330.0%0.30%
+1.7%
XBI NewSPDR S&P Biotech ETFs&p biotech etf$8,597,00095,649
+100.0%
0.30%
BHVN  Biohaven Pharmaceutical Holding Company Ltd.$8,321,000
-14.0%
70,1760.0%0.29%
-6.1%
ALGN BuyAlign Technology, Inc.$8,238,000
+68.1%
18,894
+153.3%
0.29%
+82.9%
ASND  Ascendis Pharma A/Ssponsored adr$7,956,000
-12.8%
67,7940.0%0.28%
-4.8%
ADUS  Addus HomeCare Corp.$7,802,000
-0.2%
83,6320.0%0.27%
+8.7%
SBRA  Sabra Health Care REIT, Inc.$7,604,000
+10.0%
510,6600.0%0.27%
+20.3%
ANTM  Anthem, Inc.$7,193,000
+6.0%
14,6440.0%0.25%
+16.1%
DNLI  Denali Therapeutics Inc.$7,155,000
-27.9%
222,4200.0%0.25%
-21.3%
LTC  LTC Properties, Inc.$7,013,000
+12.7%
182,2930.0%0.25%
+23.0%
HQY NewHealthEquity, Inc.$6,967,000103,314
+100.0%
0.24%
MRTX  Mirati Therapeutics, Inc.$6,889,000
-43.9%
83,7840.0%0.24%
-38.7%
IONS  Ionis Pharmaceuticals, Inc.$6,507,000
+21.7%
175,6800.0%0.23%
+33.1%
 Caribou Biosciences, Inc.$6,420,000
-35.0%
699,3770.0%0.22%
-29.2%
AMN  AMN Healthcare Services, Inc.$6,385,000
-14.7%
61,2010.0%0.22%
-7.1%
TVTX BuyTravere Therapeutics, Inc.$6,383,000
-3.4%
247,678
+16.4%
0.22%
+5.2%
SNY  Sanofisponsored adr$6,338,000
+2.5%
123,4540.0%0.22%
+12.1%
ARWR  Arrowhead Pharmaceuticals, Inc.$6,200,000
-30.6%
134,8120.0%0.22%
-24.3%
BPMC NewBlueprint Medicines Corp.$6,213,00097,253
+100.0%
0.22%
PKI  PerkinElmer, Inc.$5,835,000
-13.2%
33,4440.0%0.20%
-5.1%
SNN  Smith & Nephew plcsponsored adr$5,797,000
-7.9%
181,7100.0%0.20%
+1.0%
ARVN  Arvinas, Inc.$5,788,000
-18.1%
85,9970.0%0.20%
-10.6%
RCM  R1 RCM Inc.$5,415,000
+5.0%
202,3510.0%0.19%
+14.5%
QGEN  Qiagen N.V.shares$5,285,000
-11.8%
107,8550.0%0.19%
-3.6%
PEAK  Healthpeak Properties, Inc.$5,163,000
-4.9%
150,3920.0%0.18%
+3.4%
PHG  Koninklijke Philips N.V.ny reg shares$5,031,000
-17.2%
164,7900.0%0.18%
-9.2%
ALKS SellAlkermes plcshares$5,002,000
-22.4%
190,122
-31.4%
0.18%
-15.4%
ACHC NewAcadia Healthcare Company, Inc.$4,738,00072,307
+100.0%
0.17%
NVAX  Novavax, Inc.$4,699,000
-48.5%
63,8000.0%0.16%
-43.9%
ADPT  Adaptive Biotechnologies Corp.$4,688,000
-50.5%
337,7220.0%0.16%
-45.9%
CYTK BuyCytokinetics, Inc.$4,413,000
+4.3%
119,898
+29.1%
0.16%
+14.0%
TEVA  Teva Pharmaceutical Industries Ltd.sponsored adr$4,316,000
+17.2%
459,6510.0%0.15%
+28.8%
NTLA  Intellia Therapeutics, Inc.$4,228,000
-38.5%
58,1800.0%0.15%
-33.0%
STE  STERIS plcshares$4,030,000
-0.7%
16,6690.0%0.14%
+8.4%
VRNA  Verona Pharma plcsponsored adr$3,752,000
-25.7%
751,9050.0%0.13%
-19.0%
VECT  VectivBio Holding AGordinary shares$3,556,000
-4.3%
756,5020.0%0.12%
+4.2%
CRSP  CRISPR Therapeutics AGnamen akt$3,457,000
-17.2%
55,0800.0%0.12%
-9.7%
GTHX  G1 Therapeutics, Inc.$3,221,000
-25.6%
423,8690.0%0.11%
-18.7%
BCRX NewBioCryst Pharmaceuticals, Inc.$3,197,000196,625
+100.0%
0.11%
XNCR NewXencor, Inc.$3,006,000112,673
+100.0%
0.11%
TAK  Takeda Pharmaceutical Company Ltd.sponsored ads$3,009,000
+5.1%
210,1460.0%0.11%
+15.2%
PTGX BuyProtagonist Therapeutics, Inc.$2,895,000
-16.2%
122,271
+21.0%
0.10%
-8.1%
HR  Healthcare Realty Trust Inc.$2,859,000
-13.1%
104,0240.0%0.10%
-5.7%
GMRE  Global Medical REIT Inc.$2,854,000
-8.1%
174,8970.0%0.10%0.0%
XRAY  DENTSPLY SIRONA Inc.$2,825,000
-11.8%
57,4000.0%0.10%
-3.9%
HLXA  Helix Acquisition Corp.class a$2,775,000
+12.2%
250,0000.0%0.10%
+21.2%
IMAB  I-Mabsponsored ads$2,640,000
-65.7%
162,5800.0%0.09%
-62.5%
BuyPyxis Oncology, Inc.$2,630,000
+77.6%
708,303
+424.7%
0.09%
+91.7%
CERE BuyCerevel Therapeutics Holdings, Inc.$2,580,000
+94.1%
73,681
+79.7%
0.09%
+111.6%
AFMD  Affimed N.V.$2,561,000
-20.8%
586,0380.0%0.09%
-13.5%
ARQT  Arcutis Biotherapeutics, Inc.$2,535,000
-7.1%
131,6330.0%0.09%
+1.1%
MRUS BuyMerus N.V.$2,519,000
+89.3%
95,290
+127.7%
0.09%
+104.7%
HTA  Healthcare Trust of America, Inc.$2,215,000
-6.1%
70,6620.0%0.08%
+2.6%
HOLX  Hologic, Inc.$2,178,000
+0.4%
28,3470.0%0.08%
+8.6%
GRTX  Galera Therapeutics, Inc.$2,138,000
-48.2%
898,3740.0%0.08%
-43.6%
AUPH  Aurinia Pharmaceuticals Inc.$2,013,000
-45.9%
162,5990.0%0.07%
-40.8%
CCXI  ChemoCentryx, Inc.$1,960,000
-31.2%
78,1970.0%0.07%
-25.0%
PRGO  Perrigo Company plcshares$1,969,000
-1.2%
51,2240.0%0.07%
+7.8%
ZLAB  Zai Lab Ltd.adr$1,904,000
-30.0%
43,3000.0%0.07%
-23.9%
FULC  Fulcrum Therapeutics, Inc.$1,828,000
+33.7%
77,2930.0%0.06%
+45.5%
ACAD  ACADIA Pharmaceuticals Inc.$1,749,000
+3.7%
72,2250.0%0.06%
+13.0%
MREO  Mereo BioPharma Group plcads$1,737,000
-30.0%
1,551,0820.0%0.06%
-23.8%
MEDP SellMedpace Holdings, Inc.$1,543,000
-62.4%
9,435
-50.0%
0.05%
-59.1%
NewStevanato Group Societa' Per Azioniordinary shares$1,432,00071,190
+100.0%
0.05%
MORF  Morphic Holding, Inc.$1,406,000
-15.3%
35,0250.0%0.05%
-7.5%
SRRK  Scholar Rock Holding Corp.$1,403,000
-48.1%
108,8330.0%0.05%
-43.7%
ITOS  iTeos Therapeutics, Inc.$1,363,000
-30.9%
42,3620.0%0.05%
-23.8%
STRO SellSutro Biopharma, Inc.$1,347,000
-72.4%
163,924
-50.0%
0.05%
-70.1%
HARP NewHarpoon Therapeutics, Inc.$1,292,000259,910
+100.0%
0.04%
ACET  Adicet Bio, Inc.$1,265,000
+14.2%
63,3290.0%0.04%
+22.2%
FATE SellFate Therapeutics, Inc.$1,227,000
-71.2%
31,652
-56.5%
0.04%
-68.6%
ASRT  Assertio Holdings, Inc.$1,178,000
+31.6%
410,5750.0%0.04%
+41.4%
 Theseus Pharmaceuticals, Inc.$1,153,000
-9.1%
100,0000.0%0.04%
-2.4%
ENDP  Endo International plcshares$1,143,000
-38.5%
494,6070.0%0.04%
-33.3%
DHC  Diversified Healthcare Trust$1,145,000
+3.6%
357,7200.0%0.04%
+11.1%
ALXO  ALX Oncology Holdings Inc.$1,119,000
-21.4%
66,2110.0%0.04%
-15.2%
DSGN  Design Therapeutics, Inc.$1,055,000
-24.6%
65,3510.0%0.04%
-17.8%
CYH  Community Health Systems, Inc.$1,049,000
-10.8%
88,3350.0%0.04%
-2.6%
SNDX NewSyndax Pharmaceuticals, Inc.$982,00056,480
+100.0%
0.03%
BEAM  Beam Therapeutics Inc.$906,000
-28.1%
15,8170.0%0.03%
-22.0%
ICPT  Intercept Pharmaceuticals, Inc.$847,000
-0.1%
52,0670.0%0.03%
+11.1%
RXDX NewPrometheus Biosciences, Inc.$835,00022,115
+100.0%
0.03%
PRAX  Praxis Precision Medicines, Inc.$766,000
-48.2%
75,0000.0%0.03%
-43.8%
DTIL  Precision BioSciences, Inc.$692,000
-58.4%
224,5340.0%0.02%
-54.7%
UHT  Universal Health Realty Income Trustshares$657,000
-1.9%
11,2580.0%0.02%
+4.5%
CHCT  Community Healthcare Trust Inc.$629,000
-10.7%
14,9000.0%0.02%
-4.3%
NHI  National Health Investors, Inc.$592,000
+2.6%
10,0380.0%0.02%
+10.5%
EWTX  Edgewise Therapeutics, Inc.$587,000
-36.5%
60,5500.0%0.02%
-30.0%
UHS SellUniversal Health Services, Inc.class b$580,000
-92.5%
4,000
-93.3%
0.02%
-92.0%
ARDX  Ardelyx, Inc.$577,000
-2.7%
539,4080.0%0.02%
+5.3%
 TScan Therapeutics, Inc.$560,000
-37.8%
200,0000.0%0.02%
-31.0%
MOR  MorphoSys AGsponsored ads$555,000
-28.0%
81,8670.0%0.02%
-24.0%
RNA NewAvidity Biosciences, Inc.$489,00026,452
+100.0%
0.02%
BCYC NewBicycle Therapeutics PLCsponsored ads$443,00010,086
+100.0%
0.02%
RPTX  Repare Therapeutics Inc.$415,000
-32.5%
29,1500.0%0.02%
-25.0%
BDTX  Black Diamond Therapeutics, Inc.$366,000
-48.0%
131,9900.0%0.01%
-43.5%
NKTX  Nkarta, Inc.$330,000
-25.8%
28,9880.0%0.01%
-14.3%
ONEM  1Life Healthcare, Inc.$346,000
-37.0%
31,2660.0%0.01%
-33.3%
FUSN  Fusion Pharmaceuticals Inc.$337,000
+86.2%
43,3940.0%0.01%
+100.0%
NewZimVie Inc.$324,00014,202
+100.0%
0.01%
SPPI  Spectrum Pharmaceuticals, Inc.$148,000
+1.4%
114,6700.0%0.01%0.0%
ABIO  ARCA biopharma, Inc.$75,000
+7.1%
32,4610.0%0.00%
+50.0%
CRBP  Corbus Pharmaceuticals Holdings, Inc.$82,000
-13.7%
154,3100.0%0.00%0.0%
VYNE  VYNE Therapeutics Inc.$88,000
-36.2%
135,3950.0%0.00%
-25.0%
FVE  AlerisLife Inc.$52,000
-26.8%
24,2370.0%0.00%0.0%
 Bellicum Pharmaceuticals, Inc.$13,000
+44.4%
6,0000.0%0.00%
NewNexGel, Inc.$8,0004,243
+100.0%
0.00%
ExitNexgel$0-4,243
-100.0%
0.00%
KALV ExitKalVista Pharmaceuticals, Inc.$0-31,594
-100.0%
-0.01%
IDYA ExitIDEAYA Biosciences, Inc.$0-20,454
-100.0%
-0.02%
KOD ExitKodiak Sciences Inc.$0-8,530
-100.0%
-0.02%
FMTX ExitForma Therapeutics Holdings, Inc.shares$0-53,186
-100.0%
-0.02%
ExitAstellas Pharma Inc.$0-88,837
-100.0%
-0.05%
ZGNX ExitZogenix, Inc.$0-88,977
-100.0%
-0.05%
TBPH ExitTheravance Biopharma, Inc.$0-656,296
-100.0%
-0.23%
MTD ExitMettler-Toledo International Inc.$0-6,650
-100.0%
-0.36%
ARNA ExitArena Pharmaceuticals, Inc.$0-175,976
-100.0%
-0.53%
Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR filed 2022-05-13
Signatures

The EDGAR filing(s) were signed by:

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
Gilead Sciences, Inc.41Q2 202312.4%
Amgen, Inc.41Q2 20235.8%
Biogen Inc.41Q2 20236.5%
Vertex Pharmaceuticals Incorporated41Q2 20235.3%
Regeneron Pharmaceuticals, Inc.41Q2 20239.1%
Illumina, Inc.41Q2 20233.4%
BioMarin Pharmaceutical Inc.41Q2 20232.9%
Teva Pharmaceutical Industries Ltd.41Q2 20233.2%
Neurocrine Biosciences, Inc.41Q2 20231.4%
McKesson Corporation41Q2 20232.2%

View Tekla Capital Management LLC's complete holdings history.

Latest significant ownerships (13-D/G)
Tekla Capital Management LLC Q1 2022 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
Rallybio CorpJanuary 23, 20231,727,0674.6%
Zyla Life SciencesSold outJanuary 29, 202100.0%
ARCA biopharma, Inc.January 24, 202036,0682.3%
Verona Pharma plcFebruary 12, 20195,296,8454.9%
Alliqua BioMedical, Inc.February 12, 2018165,0003.3%
PIERIS PHARMACEUTICALS, INC.February 12, 20181,962,3804.4%
Intellipharmaceutics International Inc.February 13, 20152,184,0009.0%
HERON THERAPEUTICS, INC. /DE/February 14, 201420,598,6134.2%
MEDWAVE INCFebruary 14, 20121,277,3729.8%
MZT Holdings, Inc.February 14, 20122,553,4204.0%

View Tekla Capital Management LLC's complete significant-ownership history.

Latest filings
TypeFiled
13F-HR2023-08-10
13F-HR2023-05-10
13F-HR2023-02-10
SC 13G/A2023-01-23
13F-HR2022-11-01
13F-HR2022-07-29
13F-HR2022-05-13
13F-HR2022-02-14
SC 13G2022-01-21
13F-HR2021-11-12

View Tekla Capital Management LLC's complete filings history.

Compare quarters

Issues

The following issues were detected while analyzing the report:

  • The reported total value is incorrect (2847415000.0 != 2847411000.0)

Export Tekla Capital Management LLC's holdings