$3.11 Billion is the total value of Tekla Capital Management LLC's 171 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 19.2% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| UNH | Buy | Unitedhealth Group Inc. | $160,863,000 | +34.5% | 320,354 | +4.6% | 5.18% | +34.4% |
| MRNA | Buy | Moderna, Inc. | $138,832,000 | -21.5% | 546,624 | +19.0% | 4.47% | -21.5% |
| AMGN | Amgen Inc. | $129,339,000 | +5.8% | 574,918 | 0.0% | 4.16% | +5.7% | |
| GILD | Sell | Gilead Sciences, Inc. | $122,461,000 | +2.6% | 1,686,565 | -1.3% | 3.94% | +2.6% |
| TMO | Buy | Thermo Fisher Scientific Inc. | $101,638,000 | +21.8% | 152,326 | +4.3% | 3.27% | +21.7% |
| HZNP | Sell | Horizon Therapeutics plcshares | $96,719,000 | -3.0% | 897,540 | -1.4% | 3.11% | -3.1% |
| REGN | Sell | Regeneron Pharmaceuticals, Inc. | $90,338,000 | +0.9% | 143,049 | -3.4% | 2.91% | +0.8% |
| JNJ | Johnson & Johnson | $88,384,000 | +5.9% | 516,652 | 0.0% | 2.84% | +5.8% | |
| ILMN | Buy | Illumina, Inc. | $86,060,000 | +9.4% | 226,212 | +16.6% | 2.77% | +9.3% |
| ABT | Sell | Abbott Laboratories | $82,090,000 | +5.8% | 583,277 | -11.2% | 2.64% | +5.7% |
| PFE | Buy | Pfizer Inc. | $69,201,000 | +257.2% | 1,171,903 | +160.2% | 2.23% | +256.9% |
| ABBV | Sell | AbbVie Inc. | $69,029,000 | +22.1% | 509,817 | -2.7% | 2.22% | +22.0% |
| DHR | Buy | Danaher Corp. | $66,578,000 | +47.1% | 202,360 | +36.1% | 2.14% | +46.9% |
| LLY | Sell | Eli Lilly and Co. | $63,650,000 | +0.0% | 230,432 | -16.3% | 2.05% | -0.0% |
| SGEN | Buy | Seagen Inc. | $61,767,000 | +75.4% | 399,527 | +92.7% | 1.99% | +75.2% |
| MRK | Sell | Merck & Co., Inc. | $60,402,000 | -1.5% | 788,122 | -3.5% | 1.94% | -1.5% |
| VRTX | Vertex Pharmaceuticals Inc. | $59,961,000 | +21.1% | 273,046 | 0.0% | 1.93% | +20.9% | |
| IDXX | IDEXX Laboratories, Inc. | $52,455,000 | +5.9% | 79,663 | 0.0% | 1.69% | +5.8% | |
| MDT | Sell | Medtronic plcshares | $52,331,000 | -30.5% | 505,860 | -15.8% | 1.68% | -30.6% |
| SYK | Buy | Stryker Corp. | $49,093,000 | +23.7% | 183,582 | +22.0% | 1.58% | +23.6% |
| MCK | Buy | McKesson Corp. | $46,861,000 | +29.4% | 188,522 | +3.8% | 1.51% | +29.3% |
| BMY | Buy | Bristol-Myers Squibb Co. | $46,578,000 | +28.6% | 747,043 | +22.0% | 1.50% | +28.6% |
| AZN | Sell | AstraZeneca PLCsponsored adr | $45,871,000 | -6.0% | 787,485 | -3.1% | 1.48% | -6.1% |
| SYNH | Buy | Syneos Health, Inc.class a | $41,389,000 | +94.2% | 403,087 | +65.4% | 1.33% | +94.2% |
| GH | Sell | Guardant Health, Inc. | $35,155,000 | -27.5% | 351,484 | -9.4% | 1.13% | -27.6% |
| CI | Sell | Cigna Corp. | $32,934,000 | -25.8% | 143,423 | -35.3% | 1.06% | -25.8% |
| BIIB | Sell | Biogen Inc. | $32,543,000 | -50.8% | 135,639 | -42.0% | 1.05% | -50.9% |
| HUM | Buy | Humana Inc. | $32,312,000 | +56.3% | 69,660 | +31.1% | 1.04% | +56.2% |
| ALNY | Alnylam Pharmaceuticals, Inc. | $32,168,000 | -10.2% | 189,695 | 0.0% | 1.04% | -10.2% | |
| MOH | Buy | Molina Healthcare, Inc. | $31,275,000 | +37.8% | 98,325 | +17.6% | 1.01% | +37.6% |
| ICLR | Icon plcshares | $30,620,000 | +18.2% | 98,871 | 0.0% | 0.98% | +18.1% | |
| ZTS | Sell | Zoetis Inc.class a | $29,893,000 | +8.0% | 122,497 | -14.1% | 0.96% | +8.0% |
| HCA | HCA Healthcare, Inc. | $28,765,000 | +5.9% | 111,961 | 0.0% | 0.93% | +5.8% | |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $28,447,000 | -27.9% | 315,897 | -25.9% | 0.92% | -28.0% |
| IQV | Buy | IQVIA Holdings Inc. | $27,693,000 | +50.8% | 98,154 | +28.1% | 0.89% | +50.8% |
| CRL | Sell | Charles River Laboratories International, Inc. | $23,357,000 | -27.9% | 61,990 | -21.0% | 0.75% | -27.9% |
| BNTX | Buy | BioNTech SEsponsored ads | $23,264,000 | +5.5% | 90,242 | +11.7% | 0.75% | +5.5% |
| EW | Sell | Edwards Lifesciences Corp. | $22,955,000 | +4.2% | 177,188 | -9.0% | 0.74% | +4.2% |
| BSX | Buy | Boston Scientific Corp. | $22,771,000 | +182.2% | 536,042 | +188.3% | 0.73% | +181.9% |
| DXCM | Sell | Dexcom, Inc. | $22,515,000 | -4.2% | 41,931 | -2.4% | 0.72% | -4.4% |
| UTHR | Sell | United Therapeutics Corp. | $21,983,000 | -17.8% | 101,737 | -29.8% | 0.71% | -17.9% |
| ISRG | Buy | Intuitive Surgical, Inc. | $20,698,000 | +4.1% | 57,606 | +188.0% | 0.67% | +4.1% |
| Sell | Rallybio Corp. | $20,408,000 | -45.7% | 2,308,670 | -0.0% | 0.66% | -45.7% | |
| RMD | Buy | ResMed Inc. | $19,432,000 | +419.6% | 74,599 | +425.8% | 0.62% | +420.8% |
| ZBH | Sell | Zimmer Biomet Holdings, Inc. | $18,045,000 | -44.6% | 142,044 | -36.2% | 0.58% | -44.7% |
| WELL | Welltower Inc. | $17,418,000 | +4.1% | 203,083 | 0.0% | 0.56% | +3.9% | |
| BGNE | BeiGene, Ltd.sponsored adr | $17,278,000 | -25.4% | 63,772 | 0.0% | 0.56% | -25.4% | |
| ARNA | Buy | Arena Pharmaceuticals, Inc. | $16,355,000 | +228.4% | 175,976 | +110.4% | 0.53% | +228.8% |
| XLV | Sell | Health Care Select Sector SPDR Fundsbi healthcare | $15,953,000 | -5.7% | 113,230 | -14.8% | 0.51% | -5.7% |
| CVS | CVS Health Corp. | $15,211,000 | +21.6% | 147,453 | 0.0% | 0.49% | +21.3% | |
| JAZZ | Buy | Jazz Pharmaceuticals plcshares | $14,946,000 | +0.6% | 117,315 | +2.9% | 0.48% | +0.6% |
| LH | Sell | Laboratory Corporation of America Holdingssponsored adr | $13,870,000 | -47.9% | 44,142 | -53.4% | 0.45% | -48.0% |
| ARGX | argenx SEsponsored adr | $13,467,000 | +16.0% | 38,456 | 0.0% | 0.43% | +15.8% | |
| NVO | Buy | Novo Nordisk A/Ssponsored adr | $13,255,000 | +44.3% | 118,349 | +23.7% | 0.43% | +44.3% |
| KRTX | Karuna Therapeutics, Inc. | $13,160,000 | +7.1% | 100,458 | 0.0% | 0.42% | +6.8% | |
| VTR | Ventas, Inc. | $12,684,000 | -7.4% | 248,131 | 0.0% | 0.41% | -7.5% | |
| OMI | Sell | Owens & Minor, Inc. | $12,535,000 | +35.8% | 288,167 | -2.3% | 0.40% | +35.7% |
| ITCI | Sell | Intra-Cellular Therapies, Inc. | $12,376,000 | +2.3% | 236,447 | -27.1% | 0.40% | +2.3% |
| MRTX | Mirati Therapeutics, Inc. | $12,290,000 | -17.1% | 83,784 | 0.0% | 0.40% | -17.2% | |
| NVS | Novartis AGsponsored adr | $11,916,000 | +7.0% | 136,225 | 0.0% | 0.38% | +6.7% | |
| RARE | Ultragenyx Pharmaceutical Inc. | $11,834,000 | -6.8% | 140,726 | 0.0% | 0.38% | -6.8% | |
| BMRN | BioMarin Pharmaceutical Inc. | $11,309,000 | +14.3% | 128,004 | 0.0% | 0.36% | +14.1% | |
| MTD | Mettler-Toledo International Inc. | $11,286,000 | +23.2% | 6,650 | 0.0% | 0.36% | +23.1% | |
| BDX | Becton, Dickinson and Co. | $10,891,000 | +2.3% | 43,307 | 0.0% | 0.35% | +2.0% | |
| QURE | Buy | uniQure N.V.shares | $10,820,000 | +42.6% | 521,693 | +120.1% | 0.35% | +42.6% |
| WAT | Waters Corp. | $10,605,000 | +4.3% | 28,461 | 0.0% | 0.34% | +4.3% | |
| NBIX | Neurocrine Biosciences, Inc. | $10,613,000 | -11.2% | 124,609 | 0.0% | 0.34% | -11.4% | |
| DNLI | Denali Therapeutics Inc. | $9,920,000 | -11.6% | 222,420 | 0.0% | 0.32% | -11.6% | |
| Caribou Biosciences, Inc. | $9,875,000 | -36.8% | 699,377 | 0.0% | 0.32% | -36.8% | ||
| MPW | Medical Properties Trust, Inc. | $9,729,000 | +17.7% | 411,743 | 0.0% | 0.31% | +17.7% | |
| BHVN | Sell | Biohaven Pharmaceutical Holding Co. Ltd. | $9,671,000 | -23.3% | 70,176 | -22.7% | 0.31% | -23.4% |
| ADPT | Adaptive Biotechnologies Corp. | $9,476,000 | -17.4% | 337,722 | 0.0% | 0.30% | -17.6% | |
| DOC | Physicians Realty Trust | $9,335,000 | +6.9% | 495,733 | 0.0% | 0.30% | +6.8% | |
| APLS | Apellis Pharmaceuticals, Inc. | $9,258,000 | +43.4% | 195,820 | 0.0% | 0.30% | +43.3% | |
| NVAX | Sell | Novavax, Inc. | $9,128,000 | -70.9% | 63,800 | -57.9% | 0.29% | -70.9% |
| ASND | Ascendis Pharma A/Ssponsored adr | $9,120,000 | -15.6% | 67,794 | 0.0% | 0.29% | -15.8% | |
| OHI | Omega Healthcare Investors, Inc. | $9,067,000 | -1.2% | 306,433 | 0.0% | 0.29% | -1.4% | |
| ARWR | Sell | Arrowhead Pharmaceuticals, Inc. | $8,938,000 | -29.9% | 134,812 | -34.0% | 0.29% | -29.9% |
| ADUS | Addus HomeCare Corp. | $7,820,000 | +17.2% | 83,632 | 0.0% | 0.25% | +17.2% | |
| UHS | Universal Health Services, Inc.class b | $7,783,000 | -6.3% | 60,023 | 0.0% | 0.25% | -6.4% | |
| IMAB | I-Mabsponsored ads | $7,705,000 | -34.6% | 162,580 | 0.0% | 0.25% | -34.6% | |
| AMN | New | AMN Healthcare Services, Inc. | $7,487,000 | – | 61,201 | +100.0% | 0.24% | – |
| TBPH | Theravance Biopharma, Inc. | $7,252,000 | +49.3% | 656,296 | 0.0% | 0.23% | +49.4% | |
| ARVN | Arvinas, Inc. | $7,064,000 | -0.0% | 85,997 | 0.0% | 0.23% | -0.4% | |
| SBRA | Sabra Health Care REIT, Inc. | $6,914,000 | -8.0% | 510,660 | 0.0% | 0.22% | -8.3% | |
| NTLA | Intellia Therapeutics, Inc. | $6,879,000 | -11.9% | 58,180 | 0.0% | 0.22% | -12.0% | |
| ANTM | Anthem, Inc. | $6,788,000 | +24.3% | 14,644 | 0.0% | 0.22% | +23.9% | |
| PKI | PerkinElmer, Inc. | $6,724,000 | +16.0% | 33,444 | 0.0% | 0.22% | +15.5% | |
| TVTX | Travere Therapeutics, Inc. | $6,607,000 | +28.0% | 212,869 | 0.0% | 0.21% | +28.3% | |
| ALKS | Sell | Alkermes plcshares | $6,450,000 | -44.1% | 277,309 | -25.8% | 0.21% | -43.9% |
| A | Agilent Technologies Inc. | $6,326,000 | +1.3% | 39,625 | 0.0% | 0.20% | +1.5% | |
| SNN | Smith & Nephew plcsponsored adr | $6,291,000 | +0.8% | 181,710 | 0.0% | 0.20% | +0.5% | |
| LTC | LTC Properties, Inc. | $6,223,000 | +7.7% | 182,293 | 0.0% | 0.20% | +7.5% | |
| SNY | Sell | Sanofisponsored adr | $6,185,000 | -16.3% | 123,454 | -19.4% | 0.20% | -16.4% |
| PHG | Koninklijke Philips N.V.ny reg shares | $6,073,000 | -17.1% | 164,790 | 0.0% | 0.20% | -17.4% | |
| QGEN | Qiagen N.V.shares | $5,995,000 | +7.6% | 107,855 | 0.0% | 0.19% | +7.8% | |
| PEAK | Healthpeak Properties, Inc. | $5,428,000 | +7.8% | 150,392 | 0.0% | 0.18% | +8.0% | |
| IONS | Sell | Ionis Pharmaceuticals, Inc. | $5,346,000 | -50.6% | 175,680 | -45.5% | 0.17% | -50.6% |
| RCM | R1 RCM Inc. | $5,158,000 | +15.8% | 202,351 | 0.0% | 0.17% | +16.1% | |
| VRNA | Verona Pharma plcsponsored adr | $5,053,000 | +22.6% | 751,905 | 0.0% | 0.16% | +22.6% | |
| ALGN | Align Technology, Inc. | $4,902,000 | -1.2% | 7,459 | 0.0% | 0.16% | -1.2% | |
| STRO | Sell | Sutro Biopharma, Inc. | $4,878,000 | -35.5% | 327,850 | -18.1% | 0.16% | -35.4% |
| GTHX | Sell | G1 Therapeutics, Inc. | $4,328,000 | -48.3% | 423,869 | -32.1% | 0.14% | -48.5% |
| FATE | Fate Therapeutics, Inc. | $4,255,000 | -1.3% | 72,727 | 0.0% | 0.14% | -1.4% | |
| CYTK | New | Cytokinetics, Inc. | $4,233,000 | – | 92,871 | +100.0% | 0.14% | – |
| CRSP | Sell | CRISPR Therapeutics AGnamen akt | $4,174,000 | -77.0% | 55,080 | -66.1% | 0.13% | -77.1% |
| GRTX | Galera Therapeutics, Inc. | $4,124,000 | -43.3% | 898,374 | 0.0% | 0.13% | -43.2% | |
| MEDP | Medpace Holdings, Inc. | $4,107,000 | +15.0% | 18,871 | 0.0% | 0.13% | +14.8% | |
| STE | STERIS plcshares | $4,057,000 | +19.1% | 16,669 | 0.0% | 0.13% | +19.1% | |
| AUPH | Sell | Aurinia Pharmaceuticals Inc. | $3,719,000 | -33.5% | 162,599 | -35.7% | 0.12% | -33.3% |
| VECT | VectivBio Holding AGshares | $3,714,000 | -30.9% | 756,502 | 0.0% | 0.12% | -30.6% | |
| TEVA | Sell | Teva Pharmaceutical Industries Ltd.sponsored adr | $3,682,000 | -37.8% | 459,651 | -24.4% | 0.12% | -38.2% |
| PTGX | Buy | Protagonist Therapeutics, Inc. | $3,455,000 | +126.1% | 101,037 | +17.2% | 0.11% | +126.5% |
| HR | Healthcare Realty Trust Inc. | $3,291,000 | +6.2% | 104,024 | 0.0% | 0.11% | +6.0% | |
| AFMD | Affimed N.V. | $3,235,000 | -10.7% | 586,038 | 0.0% | 0.10% | -11.1% | |
| XRAY | Sell | DENTSPLY SIRONA Inc. | $3,202,000 | -85.0% | 57,400 | -84.4% | 0.10% | -85.0% |
| GMRE | Global Medical REIT Inc. | $3,104,000 | +20.7% | 174,897 | 0.0% | 0.10% | +20.5% | |
| CCXI | ChemoCentryx, Inc. | $2,847,000 | +112.9% | 78,197 | 0.0% | 0.09% | +114.0% | |
| TAK | Takeda Pharmaceutical Co. Ltd.sponsored ads | $2,864,000 | -16.8% | 210,146 | 0.0% | 0.09% | -17.1% | |
| ARQT | Arcutis Biotherapeutics, Inc. | $2,730,000 | -13.2% | 131,633 | 0.0% | 0.09% | -12.9% | |
| ZLAB | Buy | Zai Lab Ltd.adr | $2,721,000 | -31.2% | 43,300 | +15.4% | 0.09% | -30.7% |
| SRRK | Scholar Rock Holding Corp. | $2,703,000 | -24.8% | 108,833 | 0.0% | 0.09% | -25.0% | |
| HLXA | Helix Acquisition Corp.class a | $2,473,000 | +0.2% | 250,000 | 0.0% | 0.08% | +1.3% | |
| MREO | Mereo BioPharma Group plcads | $2,482,000 | -33.9% | 1,551,082 | 0.0% | 0.08% | -33.9% | |
| HTA | Healthcare Trust of America, Inc. | $2,359,000 | +12.5% | 70,662 | 0.0% | 0.08% | +13.4% | |
| HOLX | Hologic, Inc. | $2,170,000 | +3.7% | 28,347 | 0.0% | 0.07% | +4.5% | |
| PRGO | Perrigo Co. plcshares | $1,993,000 | -17.8% | 51,224 | 0.0% | 0.06% | -17.9% | |
| ITOS | iTeos Therapeutics, Inc. | $1,972,000 | +72.4% | 42,362 | 0.0% | 0.06% | +70.3% | |
| ENDP | Endo International plcshares | $1,860,000 | +16.0% | 494,607 | 0.0% | 0.06% | +15.4% | |
| ACAD | New | ACADIA Pharmaceuticals Inc. | $1,686,000 | – | 72,225 | +100.0% | 0.05% | – |
| MORF | Morphic Holding, Inc. | $1,659,000 | -16.4% | 35,025 | 0.0% | 0.05% | -17.2% | |
| DTIL | Buy | Precision BioSciences, Inc. | $1,662,000 | +128.6% | 224,534 | +256.4% | 0.05% | +130.4% |
| New | Pyxis Oncology, Inc. | $1,481,000 | – | 135,000 | +100.0% | 0.05% | – | |
| PRAX | Praxis Precision Medicines, Inc. | $1,478,000 | +6.6% | 75,000 | 0.0% | 0.05% | +6.7% | |
| ZGNX | Zogenix, Inc. | $1,446,000 | +7.0% | 88,977 | 0.0% | 0.05% | +6.8% | |
| ALXO | Buy | ALX Oncology Holdings Inc. | $1,423,000 | +171.6% | 66,211 | +832.7% | 0.05% | +170.6% |
| New | Astellas Pharma Inc. | $1,445,000 | – | 88,837 | +100.0% | 0.05% | – | |
| DSGN | New | Design Therapeutics, Inc. | $1,399,000 | – | 65,351 | +100.0% | 0.04% | – |
| FULC | Buy | Fulcrum Therapeutics, Inc. | $1,367,000 | +10.4% | 77,293 | +76.1% | 0.04% | +10.0% |
| MRUS | New | Merus N.V. | $1,331,000 | – | 41,857 | +100.0% | 0.04% | – |
| CERE | New | Cerevel Therapeutics Holdings, Inc. | $1,329,000 | – | 41,003 | +100.0% | 0.04% | – |
| New | Theseus Pharmaceuticals, Inc. | $1,268,000 | – | 100,000 | +100.0% | 0.04% | – | |
| BEAM | New | Beam Therapeutics Inc. | $1,260,000 | – | 15,817 | +100.0% | 0.04% | – |
| CYH | Sell | Community Health Systems, Inc. | $1,176,000 | -1.0% | 88,335 | -13.0% | 0.04% | 0.0% |
| DHC | Diversified Healthcare Trust | $1,105,000 | -8.9% | 357,720 | 0.0% | 0.04% | -7.7% | |
| ACET | New | Adicet Bio, Inc. | $1,108,000 | – | 63,329 | +100.0% | 0.04% | – |
| EWTX | New | Edgewise Therapeutics, Inc. | $925,000 | – | 60,550 | +100.0% | 0.03% | – |
| TScan Therapeutics, Inc. | $900,000 | -46.0% | 200,000 | 0.0% | 0.03% | -46.3% | ||
| ASRT | Assertio Holdings, Inc. | $895,000 | +140.6% | 410,575 | 0.0% | 0.03% | +141.7% | |
| ICPT | Intercept Pharmaceuticals, Inc. | $848,000 | +9.7% | 52,067 | 0.0% | 0.03% | +8.0% | |
| MOR | MorphoSys AGsponsored ads | $771,000 | -19.9% | 81,867 | 0.0% | 0.02% | -19.4% | |
| FMTX | Sell | Forma Therapeutics Holdings, Inc.shares | $756,000 | -78.2% | 53,186 | -64.5% | 0.02% | -78.6% |
| KOD | New | Kodiak Sciences Inc. | $723,000 | – | 8,530 | +100.0% | 0.02% | – |
| CHCT | Community Healthcare Trust Inc. | $704,000 | +4.6% | 14,900 | 0.0% | 0.02% | +4.5% | |
| BDTX | Black Diamond Therapeutics, Inc. | $704,000 | -37.0% | 131,990 | 0.0% | 0.02% | -36.1% | |
| UHT | Universal Health Realty Income Trustshares | $670,000 | +7.7% | 11,258 | 0.0% | 0.02% | +10.0% | |
| RPTX | New | Repare Therapeutics Inc. | $615,000 | – | 29,150 | +100.0% | 0.02% | – |
| ARDX | Ardelyx, Inc. | $593,000 | -16.7% | 539,408 | 0.0% | 0.02% | -17.4% | |
| NHI | National Health Investors, Inc. | $577,000 | +7.4% | 10,038 | 0.0% | 0.02% | +11.8% | |
| ONEM | 1Life Healthcare, Inc. | $549,000 | -13.3% | 31,266 | 0.0% | 0.02% | -10.0% | |
| IDYA | New | IDEAYA Biosciences, Inc. | $484,000 | – | 20,454 | +100.0% | 0.02% | – |
| NKTX | Nkarta, Inc. | $445,000 | -44.8% | 28,988 | 0.0% | 0.01% | -46.2% | |
| KALV | Sell | KalVista Pharmaceuticals, Inc. | $418,000 | -76.0% | 31,594 | -68.4% | 0.01% | -76.8% |
| FUSN | Fusion Pharmaceuticals Inc. | $181,000 | -47.4% | 43,394 | 0.0% | 0.01% | -45.5% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $146,000 | -41.6% | 114,670 | 0.0% | 0.01% | -37.5% | |
| VYNE | VYNE Therapeutics Inc. | $138,000 | -26.6% | 135,395 | 0.0% | 0.00% | -33.3% | |
| CRBP | Sell | Corbus Pharmaceuticals Holdings, Inc. | $95,000 | -77.5% | 154,310 | -62.7% | 0.00% | -78.6% |
| ABIO | ARCA biopharma, Inc. | $70,000 | -27.1% | 32,461 | 0.0% | 0.00% | -33.3% | |
| FVE | Five Star Senior Living Inc. | $71,000 | -33.0% | 24,237 | 0.0% | 0.00% | -33.3% | |
| New | Nexgel | $11,000 | – | 4,243 | +100.0% | 0.00% | – | |
| Bellicum Pharmaceuticals, Inc. | $9,000 | -50.0% | 6,000 | 0.0% | 0.00% | -100.0% | ||
| OGN | Exit | Organon & Co. | $0 | – | -3,717 | -100.0% | -0.00% | – |
| GMDA | Exit | Gamida Cell Ltd.shares | $0 | – | -118,142 | -100.0% | -0.02% | – |
| BOLT | Exit | Bolt Biotherapeutics, Inc. | $0 | – | -65,025 | -100.0% | -0.03% | – |
| BCEL | Exit | Atreca, Inc. | $0 | – | -229,372 | -100.0% | -0.05% | – |
| CDXS | Exit | Codexis, Inc. | $0 | – | -80,448 | -100.0% | -0.06% | – |
| TCRR | Exit | TCR2 Therapeutics Inc. | $0 | – | -235,808 | -100.0% | -0.06% | – |
| STOK | Exit | Stoke Therapeutics, Inc. | $0 | – | -99,263 | -100.0% | -0.08% | – |
| XENE | Exit | Xenon Pharmaceuticals Inc. | $0 | – | -169,030 | -100.0% | -0.08% | – |
| TECH | Exit | Bio-Techne Corp. | $0 | – | -5,400 | -100.0% | -0.08% | – |
| WST | Exit | West Pharmaceutical Services, Inc. | $0 | – | -6,240 | -100.0% | -0.08% | – |
| Exit | Stevanato Group SpAshares | $0 | – | -137,872 | -100.0% | -0.11% | – | |
| VIR | Exit | Vir Biotechnology, Inc. | $0 | – | -81,400 | -100.0% | -0.11% | – |
| KURA | Exit | Kura Oncology, Inc. | $0 | – | -273,463 | -100.0% | -0.16% | – |
| FOLD | Exit | Amicus Therapeutics, Inc. | $0 | – | -587,277 | -100.0% | -0.18% | – |
| TPTX | Exit | Turning Point Therapeutics, Inc. | $0 | – | -119,324 | -100.0% | -0.26% | – |
| CTLT | Exit | Catalent, Inc. | $0 | – | -143,913 | -100.0% | -0.62% | – |
| EXAS | Exit | Exact Sciences Corp. | $0 | – | -225,282 | -100.0% | -0.69% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.