$2.91 Billion is the total value of Tekla Capital Management LLC's 196 reported holdings in Q1 2021. The portfolio turnover from Q4 2020 to Q1 2021 was 29.0% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GILD | Buy | Gilead Sciences, Inc. | $117,362,000 | +43.3% | 1,815,906 | +29.2% | 4.04% | +40.3% |
| AMGN | Amgen Inc. | $103,644,000 | +8.2% | 416,560 | 0.0% | 3.56% | +5.9% | |
| JNJ | Buy | Johnson & Johnson | $99,409,000 | +15.5% | 604,864 | +10.6% | 3.42% | +13.1% |
| ILMN | Sell | Illumina, Inc. | $94,783,000 | -0.5% | 246,793 | -4.2% | 3.26% | -2.6% |
| ABT | Buy | Abbott Laboratories | $89,120,000 | +88.8% | 743,657 | +72.5% | 3.07% | +84.8% |
| VRTX | Buy | Vertex Pharmaceuticals Inc. | $84,943,000 | +17.7% | 395,288 | +29.5% | 2.92% | +15.3% |
| UNH | Sell | Unitedhealth Group Inc. | $78,985,000 | +2.8% | 212,285 | -3.1% | 2.72% | +0.6% |
| HZNP | Buy | Horizon Therapeutics plcshares | $74,638,000 | +119.4% | 810,932 | +74.4% | 2.57% | +114.8% |
| REGN | Sell | Regeneron Pharmaceuticals, Inc. | $72,629,000 | -16.2% | 153,505 | -14.4% | 2.50% | -18.0% |
| BIIB | Biogen Inc. | $69,055,000 | +14.3% | 246,844 | 0.0% | 2.38% | +11.8% | |
| ABBV | AbbVie Inc. | $67,070,000 | +1.0% | 619,759 | 0.0% | 2.31% | -1.1% | |
| MRNA | Buy | Moderna, Inc. | $61,848,000 | +138.5% | 472,302 | +90.3% | 2.13% | +133.5% |
| ANTM | Buy | Anthem, Inc. | $59,147,000 | +396.1% | 164,777 | +343.7% | 2.04% | +385.7% |
| MDT | Sell | Medtronic plcshares | $58,145,000 | -7.2% | 492,214 | -8.0% | 2.00% | -9.2% |
| BMY | Sell | Bristol-Myers Squibb Co. | $56,341,000 | -8.2% | 892,453 | -9.8% | 1.94% | -10.2% |
| LLY | Buy | Eli Lilly and Co. | $54,573,000 | +36.1% | 292,114 | +23.0% | 1.88% | +33.2% |
| TMO | Sell | Thermo Fisher Scientific Inc. | $51,869,000 | -12.7% | 113,653 | -10.9% | 1.78% | -14.6% |
| CI | Buy | Cigna Corp. | $45,912,000 | +62.5% | 189,921 | +39.9% | 1.58% | +59.0% |
| DHR | Sell | Danaher Corp. | $43,044,000 | -11.9% | 191,240 | -13.0% | 1.48% | -13.7% |
| MRK | Sell | Merck & Co., Inc. | $41,760,000 | -9.0% | 541,703 | -3.4% | 1.44% | -10.9% |
| SYK | Sell | Stryker Corp. | $36,983,000 | -1.6% | 151,830 | -1.0% | 1.27% | -3.6% |
| ZBH | Sell | Zimmer Biomet Holdings, Inc. | $33,267,000 | +0.9% | 207,814 | -2.9% | 1.14% | -1.3% |
| SGEN | Sell | Seagen Inc. | $31,312,000 | -39.1% | 225,490 | -23.2% | 1.08% | -40.4% |
| WAT | Sell | Waters Corp. | $29,187,000 | +7.7% | 102,710 | -6.2% | 1.00% | +5.5% |
| HCA | Sell | HCA Healthcare, Inc. | $28,797,000 | +0.0% | 152,897 | -12.7% | 0.99% | -2.1% |
| DXCM | Dexcom, Inc. | $26,826,000 | -2.8% | 74,643 | 0.0% | 0.92% | -4.8% | |
| RMD | ResMed Inc. | $25,677,000 | -8.7% | 132,344 | 0.0% | 0.88% | -10.6% | |
| PFE | Pfizer Inc. | $25,552,000 | -1.6% | 705,259 | 0.0% | 0.88% | -3.6% | |
| LH | Buy | Laboratory Corp. of America Holdingssponsored adr | $25,396,000 | +93.1% | 99,580 | +54.1% | 0.87% | +89.2% |
| EXEL | Sell | Exelixis, Inc. | $24,870,000 | -1.4% | 1,100,920 | -12.4% | 0.86% | -3.5% |
| MCK | Sell | McKesson Corp. | $24,565,000 | +8.3% | 125,948 | -3.4% | 0.84% | +6.0% |
| GH | Buy | Guardant Health, Inc. | $24,230,000 | +59.5% | 158,727 | +34.7% | 0.83% | +56.0% |
| STE | STERIS plcshares | $24,149,000 | +0.5% | 126,779 | 0.0% | 0.83% | -1.5% | |
| XRAY | Sell | DENTSPLY SIRONA Inc. | $22,425,000 | +17.0% | 351,427 | -4.0% | 0.77% | +14.6% |
| EXAS | Buy | Exact Sciences Corp. | $22,047,000 | +162.1% | 167,302 | +163.5% | 0.76% | +156.1% |
| ALNY | Sell | Alnylam Pharmaceuticals, Inc. | $21,871,000 | -3.8% | 154,902 | -11.4% | 0.75% | -5.9% |
| NBIX | Sell | Neurocrine Biosciences, Inc. | $20,704,000 | -26.6% | 212,891 | -27.6% | 0.71% | -28.2% |
| SYNH | Buy | Syneos Health, Inc.class a | $20,680,000 | +55.5% | 272,647 | +39.7% | 0.71% | +52.2% |
| EW | Sell | Edwards Lifesciences Corp. | $19,969,000 | -17.4% | 238,755 | -9.9% | 0.69% | -19.1% |
| NVAX | Buy | Novavax, Inc. | $19,069,000 | +123.3% | 105,176 | +37.3% | 0.66% | +118.7% |
| ALLK | Buy | Allakos Inc. | $18,783,000 | +2.5% | 163,645 | +25.0% | 0.65% | +0.3% |
| CRSP | Buy | CRISPR Therapeutics AGnamen akt | $18,394,000 | +57.6% | 150,958 | +98.1% | 0.63% | +54.4% |
| ARGX | Buy | Argenx SEsponsored adr | $17,720,000 | -2.3% | 64,344 | +4.3% | 0.61% | -4.2% |
| AZN | AstraZeneca PLCsponsored adr | $17,120,000 | -0.5% | 344,333 | 0.0% | 0.59% | -2.6% | |
| IDXX | IDEXX Laboratories, Inc. | $17,035,000 | -2.1% | 34,814 | 0.0% | 0.59% | -4.1% | |
| ALXN | Sell | Alexion Pharmaceuticals, Inc. | $16,926,000 | -78.4% | 110,693 | -77.9% | 0.58% | -78.9% |
| CVS | CVS Health Corp. | $16,550,000 | +10.1% | 219,995 | 0.0% | 0.57% | +7.8% | |
| IOVA | Buy | Iovance Biotherapeutics, Inc. | $16,482,000 | +31.0% | 520,595 | +92.0% | 0.57% | +28.3% |
| PRAH | Sell | PRA Health Sciences, Inc. | $15,938,000 | -27.7% | 103,943 | -40.9% | 0.55% | -29.3% |
| ISRG | Intuitive Surgical, Inc. | $15,736,000 | -9.7% | 21,296 | 0.0% | 0.54% | -11.6% | |
| HUM | Sell | Humana Inc. | $15,655,000 | -53.9% | 37,341 | -54.9% | 0.54% | -54.9% |
| ASND | Buy | Ascendis Pharma A/Ssponsored adr | $15,251,000 | -5.0% | 118,336 | +23.0% | 0.52% | -6.9% |
| WELL | Welltower Inc. | $14,547,000 | +10.9% | 203,083 | 0.0% | 0.50% | +8.5% | |
| MRTX | Mirati Therapeutics, Inc. | $14,352,000 | -22.0% | 83,784 | 0.0% | 0.49% | -23.6% | |
| BGNE | Buy | BeiGene, Ltd.sponsored adr | $14,059,000 | +92.4% | 40,389 | +42.8% | 0.48% | +88.3% |
| DCPH | Buy | Deciphera Pharmaceuticals, Inc. | $13,797,000 | +294.0% | 307,703 | +401.4% | 0.48% | +286.2% |
| ARNA | Sell | Arena Pharmaceuticals, Inc. | $13,627,000 | -29.9% | 196,385 | -22.4% | 0.47% | -31.3% |
| ADPT | Buy | Adaptive Biotechnologies Corp. | $13,597,000 | -19.6% | 337,722 | +18.1% | 0.47% | -21.2% |
| IQV | Sell | IQVIA Holdings Inc. | $13,494,000 | -1.0% | 69,866 | -8.2% | 0.46% | -3.1% |
| STRO | Sell | Sutro Biopharma, Inc. | $13,060,000 | -14.4% | 573,823 | -18.3% | 0.45% | -16.2% |
| CRL | Buy | Charles River Laboratories International, Inc. | $12,484,000 | +77.5% | 43,074 | +53.0% | 0.43% | +73.7% |
| FATE | Sell | Fate Therapeutics, Inc. | $12,396,000 | -18.0% | 150,343 | -9.6% | 0.43% | -19.8% |
| BPMC | Blueprint Medicines Corp. | $11,930,000 | -13.3% | 122,699 | 0.0% | 0.41% | -15.3% | |
| NVS | Sell | Novartis AGsponsored adr | $11,645,000 | -14.7% | 136,225 | -5.7% | 0.40% | -16.5% |
| MTD | Mettler-Toledo International Inc. | $11,326,000 | +1.4% | 9,800 | 0.0% | 0.39% | -0.5% | |
| TPTX | Turning Point Therapeutics, Inc. | $11,287,000 | -22.4% | 119,324 | 0.0% | 0.39% | -24.1% | |
| OHI | Omega Healthcare Investors, Inc. | $11,225,000 | +0.9% | 306,433 | 0.0% | 0.39% | -1.3% | |
| RARE | Ultragenyx Pharmaceutical Inc. | $11,099,000 | -17.7% | 97,480 | 0.0% | 0.38% | -19.4% | |
| VTR | Ventas, Inc. | $11,100,000 | +8.8% | 208,108 | 0.0% | 0.38% | +6.4% | |
| JAZZ | Jazz Pharmaceuticals plcshares | $11,088,000 | -0.4% | 67,456 | 0.0% | 0.38% | -2.6% | |
| UTHR | United Therapeutics Corp.class b | $10,624,000 | +10.2% | 63,513 | 0.0% | 0.36% | +7.7% | |
| BDX | Sell | Becton, Dickinson and Co. | $10,530,000 | -68.1% | 43,307 | -67.1% | 0.36% | -68.7% |
| KRTX | Karuna Therapeutics, Inc. | $10,248,000 | +18.4% | 85,236 | 0.0% | 0.35% | +16.1% | |
| OMI | Owens & Minor, Inc. | $10,000,000 | +39.0% | 266,023 | 0.0% | 0.34% | +36.0% | |
| IONS | Buy | Ionis Pharmaceuticals, Inc. | $9,728,000 | -10.9% | 216,371 | +12.0% | 0.34% | -12.8% |
| BMRN | Sell | BioMarin Pharmaceutical Inc. | $9,666,000 | -60.4% | 128,004 | -54.0% | 0.33% | -61.3% |
| SRPT | Sell | Sarepta Therapeutics, Inc. | $9,613,000 | -72.7% | 128,987 | -37.5% | 0.33% | -73.2% |
| UHS | New | Universal Health Services, Inc.class b | $9,514,000 | – | 71,323 | +100.0% | 0.33% | – |
| GTHX | New | G1 Therapeutics, Inc. | $9,426,000 | – | 391,754 | +100.0% | 0.32% | – |
| TBPH | Theravance Biopharma, Inc. | $9,313,000 | +14.9% | 456,296 | 0.0% | 0.32% | +12.3% | |
| MOH | Molina Healthcare, Inc. | $9,296,000 | +9.9% | 39,769 | 0.0% | 0.32% | +7.7% | |
| GRTX | Galera Therapeutics, Inc. | $9,189,000 | -13.8% | 1,041,845 | 0.0% | 0.32% | -15.7% | |
| ZTS | Zoetis Inc.class a | $8,901,000 | -4.8% | 56,521 | 0.0% | 0.31% | -7.0% | |
| SBRA | Sabra Health Care REIT, Inc. | $8,865,000 | -0.1% | 510,660 | 0.0% | 0.30% | -2.2% | |
| ARWR | Arrowhead Pharmaceuticals, Inc. | $8,812,000 | -13.6% | 132,886 | 0.0% | 0.30% | -15.4% | |
| MPW | Medical Properties Trust, Inc. | $8,762,000 | -2.3% | 411,743 | 0.0% | 0.30% | -4.4% | |
| INCY | Buy | Incyte Corp. | $8,752,000 | +7.9% | 107,687 | +15.5% | 0.30% | +5.6% |
| DOC | Physicians Realty Trust | $8,760,000 | -0.7% | 495,733 | 0.0% | 0.30% | -2.9% | |
| DNLI | Buy | Denali Therapeutics Inc. | $8,570,000 | +41.4% | 150,086 | +107.5% | 0.30% | +38.5% |
| SAGE | Sell | Sage Therapeutics, Inc. | $8,542,000 | -35.1% | 114,119 | -24.9% | 0.29% | -36.4% |
| ACAD | ACADIA Pharmaceuticals Inc. | $8,560,000 | -51.7% | 331,789 | 0.0% | 0.29% | -52.8% | |
| CTLT | New | Catalent, Inc. | $8,427,000 | – | 80,025 | +100.0% | 0.29% | – |
| IMAB | New | I-Mabsponsored ads | $8,089,000 | – | 166,896 | +100.0% | 0.28% | – |
| ITCI | Sell | Intra-Cellular Therapies, Inc. | $7,888,000 | -32.3% | 232,476 | -36.5% | 0.27% | -33.7% |
| KURA | Kura Oncology, Inc. | $7,731,000 | -13.4% | 273,463 | 0.0% | 0.27% | -15.3% | |
| TEVA | Sell | Teva Pharmaceutical Industries Ltd.sponsored adr | $7,623,000 | +8.2% | 660,551 | -9.5% | 0.26% | +5.6% |
| LTC | LTC Properties, Inc. | $7,605,000 | +7.2% | 182,293 | 0.0% | 0.26% | +5.2% | |
| BNTX | New | BioNTech SEsponsored ads | $7,514,000 | – | 68,814 | +100.0% | 0.26% | – |
| CCXI | ChemoCentryx, Inc. | $7,401,000 | -17.3% | 144,447 | 0.0% | 0.26% | -18.8% | |
| BSX | Sell | Boston Scientific Corp. | $7,186,000 | -18.8% | 185,931 | -24.4% | 0.25% | -20.6% |
| A | Agilent Technologies, Inc. | $6,678,000 | +7.3% | 52,525 | 0.0% | 0.23% | +5.0% | |
| REPL | New | Replimune Group, Inc. | $6,684,000 | – | 219,060 | +100.0% | 0.23% | – |
| APLS | Sell | Apellis Pharmaceuticals, Inc. | $6,545,000 | -47.0% | 152,538 | -29.4% | 0.22% | -48.2% |
| VRNA | Verona Pharma plcsponsored adr | $6,286,000 | +19.4% | 751,905 | 0.0% | 0.22% | +16.8% | |
| FOLD | Buy | Amicus Therapeutics, Inc. | $6,142,000 | -34.4% | 621,659 | +53.3% | 0.21% | -35.9% |
| YMAB | Buy | Y-mAbs Therapeutics, Inc. | $5,982,000 | +57.8% | 197,820 | +158.4% | 0.21% | +54.9% |
| ARVN | Buy | Arvinas, Inc. | $5,684,000 | -8.9% | 85,997 | +17.1% | 0.20% | -10.5% |
| Sell | Trillium Therapeutics Inc. | $5,684,000 | -52.8% | 529,226 | -35.3% | 0.20% | -53.7% | |
| MORF | New | Morphic Holding, Inc. | $5,667,000 | – | 89,559 | +100.0% | 0.20% | – |
| BCEL | Atreca, Inc. | $5,403,000 | -5.1% | 352,424 | 0.0% | 0.19% | -7.0% | |
| ALGN | Sell | Align Technology, Inc. | $5,375,000 | +0.2% | 9,925 | -1.2% | 0.18% | -2.1% |
| TDOC | Sell | Teladoc Health, Inc. | $5,391,000 | -52.3% | 29,664 | -47.5% | 0.18% | -53.4% |
| TVTX | New | Travere Therapeutics, Inc. | $5,315,000 | – | 212,869 | +100.0% | 0.18% | – |
| TCRR | New | TCR2 Therapeutics Inc. | $5,207,000 | – | 235,808 | +100.0% | 0.18% | – |
| AUPH | Buy | Aurinia Pharmaceuticals Inc. | $5,167,000 | +24.3% | 397,920 | +32.4% | 0.18% | +21.9% |
| AMED | Amedisys, Inc. | $5,136,000 | -9.7% | 19,395 | 0.0% | 0.18% | -11.5% | |
| ZLAB | Zai Lab Ltd.adr | $5,007,000 | -1.4% | 37,523 | 0.0% | 0.17% | -3.4% | |
| PEAK | Healthpeak Properties, Inc. | $4,773,000 | +5.0% | 150,392 | 0.0% | 0.16% | +2.5% | |
| PKI | PerkinElmer, Inc. | $4,759,000 | -10.6% | 37,094 | 0.0% | 0.16% | -12.3% | |
| COGT | Cogent Biosciences, Inc. | $4,721,000 | -21.8% | 537,742 | 0.0% | 0.16% | -23.6% | |
| ICLR | New | Icon plcshares | $4,633,000 | – | 23,592 | +100.0% | 0.16% | – |
| BBIO | New | BridgeBio Pharma, Inc. | $4,602,000 | – | 74,714 | +100.0% | 0.16% | – |
| PSNL | New | Personalis, Inc. | $4,423,000 | – | 179,731 | +100.0% | 0.15% | – |
| CNC | Sell | Centene Corp. | $4,301,000 | -14.8% | 67,290 | -20.0% | 0.15% | -16.4% |
| NTLA | New | Intellia Therapeutics, Inc. | $4,268,000 | – | 53,180 | +100.0% | 0.15% | – |
| QURE | uniQure N.V.shares | $4,211,000 | -6.8% | 125,003 | 0.0% | 0.14% | -8.8% | |
| VIR | New | Vir Biotechnology, Inc. | $4,173,000 | – | 81,400 | +100.0% | 0.14% | – |
| FMTX | Forma Therapeutics Holdings, Inc.shares | $4,198,000 | -19.7% | 149,825 | 0.0% | 0.14% | -21.7% | |
| SNY | Sanofisponsored adr | $4,034,000 | +1.8% | 81,554 | 0.0% | 0.14% | 0.0% | |
| ARDX | Ardelyx, Inc. | $4,023,000 | +2.3% | 607,698 | 0.0% | 0.14% | 0.0% | |
| JNCE | New | Jounce Therapeutics, Inc. | $3,926,000 | – | 382,237 | +100.0% | 0.14% | – |
| ENDP | Endo International plcshares | $3,939,000 | +3.2% | 531,570 | 0.0% | 0.14% | +0.7% | |
| ADUS | Addus HomeCare Corp. | $3,937,000 | -10.7% | 37,640 | 0.0% | 0.14% | -12.9% | |
| TAK | Takeda Pharmaceutical Co. Ltd.sponsored ads | $3,837,000 | +0.3% | 210,146 | 0.0% | 0.13% | -1.5% | |
| RETA | Reata Pharmaceuticals, Inc.class a | $3,810,000 | -19.4% | 38,219 | 0.0% | 0.13% | -21.1% | |
| ARQT | New | Arcutis Biotherapeutics, Inc. | $3,808,000 | – | 131,633 | +100.0% | 0.13% | – |
| SNN | Smith & Nephew plcshares | $3,773,000 | -10.1% | 99,560 | 0.0% | 0.13% | -12.2% | |
| NKTR | Nektar Therapeutics | $3,609,000 | +17.7% | 180,438 | 0.0% | 0.12% | +14.8% | |
| MREO | New | Mereo BioPharma Group plcads | $3,361,000 | – | 997,290 | +100.0% | 0.12% | – |
| INSM | Insmed Inc. | $3,351,000 | +2.3% | 98,387 | 0.0% | 0.12% | 0.0% | |
| NVO | Sell | Novo Nordisk A/Ssponsored adr | $3,264,000 | -28.0% | 48,406 | -25.4% | 0.11% | -29.6% |
| PHG | Koninklijke Philips N.V.ny reg sh | $3,247,000 | +5.3% | 56,927 | 0.0% | 0.11% | +3.7% | |
| BDTX | New | Black Diamond Therapeutics, Inc. | $3,202,000 | – | 131,990 | +100.0% | 0.11% | – |
| ALKS | Alkermes plcshares | $3,174,000 | -6.4% | 169,930 | 0.0% | 0.11% | -8.4% | |
| HR | Healthcare Realty Trust Inc. | $3,154,000 | +2.4% | 104,024 | 0.0% | 0.11% | 0.0% | |
| THC | Sell | Tenet Healthcare Corp. | $3,137,000 | -5.1% | 60,336 | -27.1% | 0.11% | -6.9% |
| MEDP | Medpace Holdings, Inc. | $3,096,000 | +17.9% | 18,871 | 0.0% | 0.11% | +15.2% | |
| RCM | New | R1 RCM Inc. | $3,047,000 | – | 123,461 | +100.0% | 0.10% | – |
| XENE | New | Xenon Pharmaceuticals Inc. | $2,970,000 | – | 165,898 | +100.0% | 0.10% | – |
| TECH | Sell | Bio-Techne Corp. | $2,903,000 | -82.3% | 7,600 | -85.3% | 0.10% | -82.7% |
| PIRS | Sell | Pieris Pharmaceuticals, Inc. | $2,630,000 | -27.4% | 1,023,348 | -29.4% | 0.09% | -29.1% |
| HLXA | Helix Acquisition Corp. | $2,559,000 | -5.5% | 250,000 | 0.0% | 0.09% | -7.4% | |
| MTEM | Sell | Molecular Templates, Inc. | $2,517,000 | +21.9% | 199,420 | -9.3% | 0.09% | +19.2% |
| PRAX | Praxis Precision Medicines, Inc. | $2,457,000 | -40.5% | 75,000 | 0.0% | 0.08% | -41.4% | |
| SRRK | Sell | Scholar Rock Holding Corp. | $2,425,000 | -57.0% | 47,869 | -58.8% | 0.08% | -58.1% |
| HOLX | Hologic, Inc. | $2,422,000 | +2.1% | 32,564 | 0.0% | 0.08% | 0.0% | |
| GMAB | Sell | Genmab A/Ssponsored ads | $2,397,000 | -77.2% | 73,015 | -71.8% | 0.08% | -77.8% |
| GMRE | Global Medical REIT Inc. | $2,293,000 | +0.4% | 174,897 | 0.0% | 0.08% | -1.2% | |
| AFMD | Buy | Affimed N.V. | $2,278,000 | +46.0% | 288,019 | +7.5% | 0.08% | +41.8% |
| HRTX | Heron Therapeutics, Inc. | $2,126,000 | -23.4% | 131,183 | 0.0% | 0.07% | -25.5% | |
| PRGO | Perrigo Co. plcshares | $2,073,000 | -9.5% | 51,224 | 0.0% | 0.07% | -12.3% | |
| HTA | Healthcare Trust of America, Inc. | $1,949,000 | +0.2% | 70,662 | 0.0% | 0.07% | -1.5% | |
| ICPT | Intercept Pharmaceuticals, Inc. | $1,779,000 | -6.6% | 77,067 | 0.0% | 0.06% | -9.0% | |
| MOR | MorphoSys AGsponsored ads | $1,785,000 | -23.1% | 81,867 | 0.0% | 0.06% | -25.6% | |
| DRNA | Dicerna Pharmaceuticals, Inc. | $1,743,000 | +16.1% | 68,150 | 0.0% | 0.06% | +13.2% | |
| ZGNX | Zogenix, Inc. | $1,737,000 | -2.4% | 88,977 | 0.0% | 0.06% | -4.8% | |
| DHC | Diversified Healthcare Trust | $1,710,000 | +16.0% | 357,720 | 0.0% | 0.06% | +13.5% | |
| CYH | Sell | Community Health Systems, Inc. | $1,589,000 | +81.6% | 117,535 | -0.2% | 0.06% | +77.4% |
| SNR | New Senior Investment Group Inc. | $1,597,000 | +20.3% | 256,398 | 0.0% | 0.06% | +17.0% | |
| MDGL | Madrigal Pharmaceuticals, Inc. | $1,560,000 | +5.2% | 13,340 | 0.0% | 0.05% | +3.8% | |
| OVID | Ovid Therapeutics Inc.sponsored adr | $1,498,000 | +74.0% | 372,733 | 0.0% | 0.05% | +73.3% | |
| KALV | New | KalVista Pharmaceuticals, Inc. | $1,285,000 | – | 50,000 | +100.0% | 0.04% | – |
| ONEM | New | 1Life Healthcare, Inc. | $1,222,000 | – | 31,266 | +100.0% | 0.04% | – |
| XLV | Health Care Select Sector SPDR Fundsbi healthcare | $1,174,000 | +2.9% | 10,055 | 0.0% | 0.04% | 0.0% | |
| ASRT | Assertio Holdings, Inc. | $1,121,000 | +91.0% | 1,642,302 | 0.0% | 0.04% | +85.7% | |
| NKTX | New | Nkarta, Inc. | $954,000 | – | 28,988 | +100.0% | 0.03% | – |
| GMDA | New | Gamida Cell Ltd.shares | $956,000 | – | 118,142 | +100.0% | 0.03% | – |
| VYNE | New | VYNE Therapeutics Inc. | $927,000 | – | 135,395 | +100.0% | 0.03% | – |
| TFX | Sell | Teleflex Inc. | $914,000 | -85.2% | 2,200 | -85.4% | 0.03% | -85.8% |
| GRFS | Grifols, S.A.sponsored adr | $819,000 | -6.3% | 47,373 | 0.0% | 0.03% | -9.7% | |
| CRBP | Corbus Pharmaceuticals Holdings, Inc. | $815,000 | +57.6% | 413,481 | 0.0% | 0.03% | +55.6% | |
| UHT | Universal Health Realty Income Trustshares | $763,000 | +5.4% | 11,258 | 0.0% | 0.03% | +4.0% | |
| RGNX | REGENXBIO Inc. | $740,000 | -24.8% | 21,700 | 0.0% | 0.02% | -28.6% | |
| NHI | National Health Investors, Inc. | $726,000 | +4.6% | 10,038 | 0.0% | 0.02% | +4.2% | |
| CHCT | Community Healthcare Trust Inc. | $687,000 | -2.1% | 14,900 | 0.0% | 0.02% | -4.0% | |
| EDIT | New | Editas Medicine, Inc. | $638,000 | – | 15,190 | +100.0% | 0.02% | – |
| DTIL | New | Precision BioSciences, Inc. | $652,000 | – | 63,001 | +100.0% | 0.02% | – |
| CBAY | CymaBay Therapeutics, Inc. | $400,000 | -20.9% | 88,102 | 0.0% | 0.01% | -22.2% | |
| CLSD | Clearside Biomedical, Inc. | $408,000 | -9.9% | 165,330 | 0.0% | 0.01% | -12.5% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $374,000 | -4.3% | 114,670 | 0.0% | 0.01% | -7.1% | |
| CLLS | Cellectissponsored adr | $242,000 | -25.3% | 11,955 | 0.0% | 0.01% | -27.3% | |
| CLDX | Celldex Therapeutics, Inc. | $145,000 | +16.9% | 7,053 | 0.0% | 0.01% | +25.0% | |
| FVE | Five Star Senior Living Inc. | $148,000 | -11.4% | 24,237 | 0.0% | 0.01% | -16.7% | |
| ABIO | ARCA biopharma, Inc. | $118,000 | -9.2% | 32,461 | 0.0% | 0.00% | -20.0% | |
| Bellicum Pharmaceuticals, Inc. | $23,000 | +9.5% | 6,000 | 0.0% | 0.00% | 0.0% | ||
| Tetraphase Pharmaceuticals, Inc. | $9,000 | 0.0% | 42,965 | 0.0% | 0.00% | – | ||
| VTRS | Exit | Viatris Inc. | $0 | – | -13,400 | -100.0% | -0.01% | – |
| VYNE | Exit | VYNE Therapeutics Inc. | $0 | – | -541,584 | -100.0% | -0.03% | – |
| ACIU | Exit | AC Immune SAshares | $0 | – | -171,813 | -100.0% | -0.03% | – |
| AERI | Exit | Aerie Pharmaceuticals, Inc. | $0 | – | -66,688 | -100.0% | -0.03% | – |
| KPTI | Exit | Karyopharm Therapeutics Inc. | $0 | – | -65,743 | -100.0% | -0.04% | – |
| BMYRT | Exit | Bristol Myers Squibb Companyright | $0 | – | -1,473,710 | -100.0% | -0.04% | – |
| ESPR | Exit | Esperion Therapeutics, Inc. | $0 | – | -41,577 | -100.0% | -0.04% | – |
| IMGN | Exit | ImmunoGen, Inc. | $0 | – | -168,190 | -100.0% | -0.04% | – |
| ALLO | Exit | Allogene Therapeutics, Inc. | $0 | – | -48,089 | -100.0% | -0.04% | – |
| MGTA | Exit | Magenta Therapeutics, Inc. | $0 | – | -192,431 | -100.0% | -0.05% | – |
| AVDL | Exit | Avadel Pharmaceuticals plcsponsored adr | $0 | – | -233,612 | -100.0% | -0.06% | – |
| GRTS | Exit | Gritstone Oncology, Inc. | $0 | – | -419,005 | -100.0% | -0.06% | – |
| MIST | Exit | Milestone Pharmaceuticals Inc. | $0 | – | -253,610 | -100.0% | -0.06% | – |
| HARP | Exit | Harpoon Therapeutics, Inc. | $0 | – | -106,419 | -100.0% | -0.06% | – |
| ALC | Exit | Alcon Inc.ordinary shares | $0 | – | -31,286 | -100.0% | -0.07% | – |
| NCNA | Exit | NuCana plcsponsored adr | $0 | – | -460,672 | -100.0% | -0.07% | – |
| BHC | Exit | Bausch Health Companies Inc. | $0 | – | -101,412 | -100.0% | -0.07% | – |
| INGN | Exit | Inogen, Inc. | $0 | – | -51,406 | -100.0% | -0.08% | – |
| AXSM | Exit | Axsome Therapeutics, Inc. | $0 | – | -31,591 | -100.0% | -0.09% | – |
| EIDX | Exit | Eidos Therapeutics, Inc. | $0 | – | -20,000 | -100.0% | -0.09% | – |
| ZYME | Exit | Zymeworks Inc. | $0 | – | -55,938 | -100.0% | -0.09% | – |
| KDMN | Exit | Kadmon Holdings, Inc. | $0 | – | -714,008 | -100.0% | -0.10% | – |
| ABMD | Exit | ABIOMED, Inc. | $0 | – | -10,812 | -100.0% | -0.12% | – |
| AXNX | Exit | Axonics Modulation Technologies, Inc. | $0 | – | -80,760 | -100.0% | -0.14% | – |
| AMRN | Exit | Amarin Corporation PLCsponsored adr | $0 | – | -849,588 | -100.0% | -0.15% | – |
| RVNC | Exit | Revance Therapeutics, Inc. | $0 | – | -213,808 | -100.0% | -0.21% | – |
| XNCR | Exit | Xencor, Inc. | $0 | – | -148,231 | -100.0% | -0.23% | – |
| TGTX | Exit | TG Therapeutics, Inc. | $0 | – | -133,269 | -100.0% | -0.24% | – |
| FGEN | Exit | FibroGen, Inc. | $0 | – | -194,270 | -100.0% | -0.25% | – |
| DGX | Exit | Quest Diagnostics Incorporated | $0 | – | -109,659 | -100.0% | -0.46% | – |
| NVCR | Exit | NovoCure Limitedordinary shares | $0 | – | -87,918 | -100.0% | -0.54% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-05-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.