$2.85 Billion is the total value of Tekla Capital Management LLC's 200 reported holdings in Q4 2020. The portfolio turnover from Q3 2020 to Q4 2020 was 16.7% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| AMGN | Sell | Amgen Inc. | $95,775,000 | -38.0% | 416,560 | -31.5% | 3.36% | -41.9% |
| ILMN | Sell | Illumina, Inc. | $95,272,000 | +9.7% | 257,493 | -8.4% | 3.35% | +2.9% |
| REGN | Sell | Regeneron Pharmaceuticals, Inc. | $86,663,000 | -25.3% | 179,385 | -13.5% | 3.04% | -30.0% |
| JNJ | Johnson & Johnson | $86,056,000 | +5.7% | 546,805 | 0.0% | 3.02% | -0.9% | |
| GILD | Sell | Gilead Sciences, Inc. | $81,877,000 | -21.2% | 1,405,371 | -14.5% | 2.88% | -26.1% |
| ALXN | Buy | Alexion Pharmaceuticals, Inc. | $78,423,000 | +156.9% | 501,942 | +88.1% | 2.76% | +140.9% |
| UNH | Buy | Unitedhealth Group Incorporated | $76,864,000 | +32.7% | 219,185 | +18.0% | 2.70% | +24.5% |
| VRTX | Sell | Vertex Pharmaceuticals Incorporated | $72,157,000 | -33.9% | 305,310 | -23.9% | 2.54% | -38.1% |
| ABBV | Sell | AbbVie Inc. | $66,407,000 | -13.3% | 619,759 | -29.1% | 2.33% | -18.7% |
| MDT | Medtronic plcshares | $62,660,000 | +12.7% | 534,914 | 0.0% | 2.20% | +5.7% | |
| BMY | Buy | Bristol Myers Squibb Company | $61,404,000 | +7.8% | 989,908 | +4.7% | 2.16% | +1.1% |
| BIIB | Buy | Biogen Inc. | $60,442,000 | -0.3% | 246,844 | +15.5% | 2.12% | -6.5% |
| TMO | Buy | Thermo Fisher Scientific Inc. | $59,412,000 | +356.7% | 127,553 | +333.0% | 2.09% | +328.7% |
| SGEN | New | Seagen Inc. | $51,424,000 | – | 293,619 | +100.0% | 1.81% | – |
| DHR | Buy | Danaher Corporation | $48,835,000 | +235.7% | 219,840 | +225.4% | 1.72% | +214.9% |
| ABT | Buy | Abbott Laboratories | $47,206,000 | +17.4% | 431,145 | +16.7% | 1.66% | +10.1% |
| MRK | Sell | Merck & Co., Inc. | $45,882,000 | -47.7% | 560,903 | -46.9% | 1.61% | -50.9% |
| LLY | Buy | Eli Lilly and Company | $40,106,000 | +52.5% | 237,537 | +33.7% | 1.41% | +43.0% |
| SYK | Sell | Stryker Corporation | $37,572,000 | +14.2% | 153,330 | -2.9% | 1.32% | +7.1% |
| SRPT | Sarepta Therapeutics, Inc. | $35,204,000 | +21.4% | 206,487 | 0.0% | 1.24% | +13.8% | |
| HZNP | Sell | Horizon Therapeutics plcshares | $34,016,000 | -27.5% | 465,016 | -23.0% | 1.20% | -32.0% |
| HUM | Sell | Humana Inc. | $33,973,000 | -4.6% | 82,807 | -3.7% | 1.19% | -10.5% |
| ZBH | Buy | Zimmer Biomet Holdings, Inc. | $32,977,000 | +26.2% | 214,014 | +11.5% | 1.16% | +18.4% |
| BDX | Becton, Dickinson and Company | $32,960,000 | +7.5% | 131,723 | 0.0% | 1.16% | +0.8% | |
| HCA | Buy | HCA Healthcare, Inc. | $28,796,000 | +181.9% | 175,097 | +113.7% | 1.01% | +164.2% |
| CI | Buy | Cigna Corporation | $28,253,000 | +134.1% | 135,712 | +90.5% | 0.99% | +119.7% |
| NBIX | Buy | Neurocrine Biosciences, Inc. | $28,202,000 | +364.0% | 294,234 | +365.5% | 0.99% | +334.6% |
| RMD | Buy | ResMed Inc. | $28,131,000 | +69.0% | 132,344 | +36.3% | 0.99% | +58.3% |
| DXCM | Buy | DexCom, Inc. | $27,597,000 | +261.0% | 74,643 | +302.5% | 0.97% | +239.2% |
| WAT | Waters Corporation | $27,095,000 | +26.4% | 109,510 | 0.0% | 0.95% | +18.6% | |
| PFE | Sell | Pfizer Inc. | $25,961,000 | -58.3% | 705,259 | -58.4% | 0.91% | -60.9% |
| MRNA | Sell | Moderna, Inc. | $25,929,000 | -20.4% | 248,192 | -46.1% | 0.91% | -25.3% |
| EXEL | Buy | Exelixis, Inc. | $25,218,000 | -5.8% | 1,256,520 | +14.7% | 0.89% | -11.7% |
| BMRN | Sell | BioMarin Pharmaceutical Inc. | $24,407,000 | -1.5% | 278,330 | -14.6% | 0.86% | -7.6% |
| EW | Sell | Edwards Lifesciences Corporation | $24,172,000 | +4.0% | 264,955 | -9.0% | 0.85% | -2.5% |
| STE | STERIS plcshares | $24,030,000 | +7.6% | 126,779 | 0.0% | 0.84% | +0.8% | |
| ALNY | Alnylam Pharmaceuticals, Inc. | $22,731,000 | -10.7% | 174,894 | 0.0% | 0.80% | -16.2% | |
| MCK | Buy | McKesson Corp. | $22,688,000 | +41.7% | 130,448 | +21.3% | 0.80% | +32.8% |
| PRAH | Buy | PRA Health Sciences, Inc. | $22,057,000 | +173.4% | 175,838 | +121.1% | 0.78% | +156.6% |
| ARNA | Buy | Arena Pharmaceuticals, Inc. | $19,436,000 | +61.8% | 252,971 | +57.5% | 0.68% | +51.8% |
| XRAY | Sell | DENTSPLY SIRONA Inc. | $19,160,000 | +7.3% | 365,927 | -10.4% | 0.67% | +0.6% |
| MRTX | Buy | Mirati Therapeutics, Inc. | $18,402,000 | +40.7% | 83,784 | +6.3% | 0.65% | +32.0% |
| ALLK | Buy | Allakos Inc. | $18,331,000 | +249.5% | 130,937 | +103.3% | 0.64% | +226.9% |
| ARGX | Argenx SEsponsored adr | $18,142,000 | +12.0% | 61,687 | 0.0% | 0.64% | +4.9% | |
| ACAD | Buy | ACADIA Pharmaceuticals Inc. | $17,737,000 | +71.5% | 331,789 | +32.3% | 0.62% | +60.6% |
| ISRG | Sell | Intuitive Surgical, Inc. | $17,422,000 | -2.1% | 21,296 | -15.1% | 0.61% | -8.2% |
| IDXX | IDEXX Laboratories, Inc. | $17,402,000 | +27.2% | 34,814 | 0.0% | 0.61% | +19.1% | |
| AZN | AstraZeneca PLCsponsored adr | $17,213,000 | -8.8% | 344,333 | 0.0% | 0.60% | -14.4% | |
| ADPT | Buy | Adaptive Biotechnologies Corporation | $16,912,000 | +1307.0% | 286,013 | +1057.2% | 0.59% | +1220.0% |
| TECH | Bio-Techne Corporation | $16,421,000 | +28.2% | 51,710 | 0.0% | 0.58% | +20.2% | |
| ASND | Sell | Ascendis Pharma A/Ssponsored adr | $16,052,000 | -17.3% | 96,246 | -23.5% | 0.56% | -22.4% |
| STRO | Buy | Sutro Biopharma, Inc. | $15,252,000 | +136.6% | 702,523 | +9.6% | 0.54% | +121.5% |
| NVCR | Sell | NovoCure Limitedordinary shares | $15,213,000 | +17.0% | 87,918 | -24.8% | 0.54% | +9.9% |
| GH | Guardant Health, Inc. | $15,189,000 | +15.3% | 117,852 | 0.0% | 0.53% | +8.1% | |
| FATE | Sell | Fate Therapeutics, Inc. | $15,123,000 | +74.0% | 166,317 | -23.5% | 0.53% | +62.9% |
| CVS | Sell | CVS Health Corporation | $15,026,000 | -33.7% | 219,995 | -43.3% | 0.53% | -37.9% |
| TPTX | Buy | Turning Point Therapeutics, Inc. | $14,540,000 | +2831.5% | 119,324 | +2001.9% | 0.51% | +2589.5% |
| BPMC | Sell | Blueprint Medicines Corporation | $13,761,000 | -12.7% | 122,699 | -27.8% | 0.48% | -18.1% |
| NVS | Sell | Novartis AGsponsored adr | $13,647,000 | +3.6% | 144,525 | -4.6% | 0.48% | -2.8% |
| IQV | Sell | IQVIA Holdings Inc. | $13,629,000 | +5.1% | 76,066 | -7.5% | 0.48% | -1.4% |
| RARE | Ultragenyx Pharmaceutical Inc. | $13,494,000 | +68.4% | 97,480 | 0.0% | 0.47% | +58.0% | |
| SYNH | Buy | Syneos Health, Inc.class a | $13,295,000 | +131.6% | 195,136 | +80.7% | 0.47% | +117.2% |
| SAGE | Buy | Sage Therapeutics, Inc. | $13,153,000 | +123.7% | 152,040 | +58.0% | 0.46% | +110.0% |
| LH | Sell | Laboratory Corporation of America Holdingssponsored adr | $13,150,000 | -0.2% | 64,603 | -7.7% | 0.46% | -6.5% |
| WELL | Welltower Inc. | $13,123,000 | +17.3% | 203,083 | 0.0% | 0.46% | +10.0% | |
| DGX | Quest Diagnostics Incorporated | $13,068,000 | +4.1% | 109,659 | 0.0% | 0.46% | -2.3% | |
| IOVA | Iovance Biotherapeutics, Inc. | $12,578,000 | +40.9% | 271,073 | 0.0% | 0.44% | +32.3% | |
| APLS | Apellis Pharmaceuticals, Inc. | $12,356,000 | +89.6% | 216,017 | 0.0% | 0.43% | +77.9% | |
| Buy | Trillium Therapeutics Inc. | $12,030,000 | +88.9% | 817,784 | +82.5% | 0.42% | +77.0% | |
| ANTM | Anthem, Inc. | $11,923,000 | +19.5% | 37,133 | 0.0% | 0.42% | +12.0% | |
| CRSP | CRISPR Therapeutics AGnamen akt | $11,670,000 | +83.1% | 76,222 | 0.0% | 0.41% | +71.5% | |
| ITCI | Buy | Intra-Cellular Therapies, Inc. | $11,644,000 | +381.6% | 366,176 | +288.6% | 0.41% | +349.5% |
| TDOC | New | Teladoc Health, Inc. | $11,302,000 | – | 56,520 | +100.0% | 0.40% | – |
| MTD | Mettler-Toledo International Inc. | $11,169,000 | +18.0% | 9,800 | 0.0% | 0.39% | +10.4% | |
| JAZZ | Jazz Pharmaceuticals plcshares | $11,134,000 | +15.8% | 67,456 | 0.0% | 0.39% | +8.6% | |
| OHI | Omega Healthcare Investors, Inc. | $11,130,000 | +21.3% | 306,433 | 0.0% | 0.39% | +13.7% | |
| IONS | Ionis Pharmaceuticals, Inc. | $10,924,000 | +19.2% | 193,201 | 0.0% | 0.38% | +11.6% | |
| GRTX | Galera Therapeutics, Inc. | $10,658,000 | +13.2% | 1,041,845 | 0.0% | 0.38% | +6.2% | |
| GMAB | Buy | Genmab A/Ssponsored ads | $10,518,000 | +55.5% | 258,672 | +40.0% | 0.37% | +45.7% |
| VTR | Ventas, Inc. | $10,206,000 | +16.9% | 208,108 | 0.0% | 0.36% | +9.8% | |
| ARWR | Buy | Arrowhead Pharmaceuticals, Inc. | $10,196,000 | +219.2% | 132,886 | +79.1% | 0.36% | +198.3% |
| UTHR | United Therapeutics Corporationclass b | $9,641,000 | +50.3% | 63,513 | 0.0% | 0.34% | +41.2% | |
| FOLD | Amicus Therapeutics, Inc. | $9,366,000 | +63.5% | 405,626 | 0.0% | 0.33% | +53.0% | |
| ZTS | Zoetis Inc.class a | $9,354,000 | +0.1% | 56,521 | 0.0% | 0.33% | -6.0% | |
| MPW | Medical Properties Trust, Inc. | $8,972,000 | +23.6% | 411,743 | 0.0% | 0.32% | +15.8% | |
| KURA | Buy | Kura Oncology, Inc. | $8,931,000 | +391.3% | 273,463 | +360.8% | 0.31% | +361.8% |
| CCXI | ChemoCentryx, Inc. | $8,944,000 | +13.0% | 144,447 | 0.0% | 0.31% | +5.7% | |
| SBRA | Sabra Health Care REIT, Inc. | $8,870,000 | +26.0% | 510,660 | 0.0% | 0.31% | +18.2% | |
| BSX | Sell | Boston Scientific Corporation | $8,847,000 | -68.8% | 246,089 | -66.8% | 0.31% | -70.7% |
| DOC | Physicians Realty Trust | $8,824,000 | -0.6% | 495,733 | 0.0% | 0.31% | -6.9% | |
| KRTX | Buy | Karuna Therapeutics, Inc. | $8,659,000 | +167.7% | 85,236 | +103.8% | 0.30% | +151.2% |
| NVAX | Buy | Novavax, Inc. | $8,540,000 | +583.7% | 76,585 | +564.6% | 0.30% | +538.3% |
| MOH | Sell | Molina Healthcare, Inc. | $8,458,000 | +8.3% | 39,769 | -6.8% | 0.30% | +1.4% |
| EXAS | Buy | Exact Sciences Corporation | $8,413,000 | +444.5% | 63,502 | +319.2% | 0.30% | +410.3% |
| INCY | Sell | Incyte Corporation | $8,111,000 | -40.8% | 93,257 | -38.9% | 0.28% | -44.4% |
| TBPH | Buy | Theravance Biopharma, Inc. | $8,108,000 | +83.7% | 456,296 | +52.9% | 0.28% | +72.7% |
| BGNE | BeiGene, Ltd.sponsored adr | $7,307,000 | -9.8% | 28,280 | 0.0% | 0.26% | -15.5% | |
| FGEN | FibroGen, Inc. | $7,205,000 | -9.8% | 194,270 | 0.0% | 0.25% | -15.4% | |
| OMI | New | Owens & Minor, Inc. | $7,196,000 | – | 266,023 | +100.0% | 0.25% | – |
| LTC | LTC Properties, Inc. | $7,093,000 | +11.6% | 182,293 | 0.0% | 0.25% | +4.6% | |
| TEVA | Sell | Teva Pharmaceutical Industries Ltd.sponsored adr | $7,045,000 | -0.5% | 730,051 | -7.1% | 0.25% | -6.4% |
| CRL | Sell | Charles River Laboratories International, Inc. | $7,035,000 | +1.0% | 28,154 | -8.5% | 0.25% | -5.4% |
| TGTX | New | TG Therapeutics, Inc. | $6,933,000 | – | 133,269 | +100.0% | 0.24% | – |
| XNCR | Xencor, Inc. | $6,467,000 | +12.5% | 148,231 | 0.0% | 0.23% | +5.6% | |
| ARVN | New | Arvinas, Inc. | $6,239,000 | – | 73,459 | +100.0% | 0.22% | – |
| A | Agilent Technologies, Inc. | $6,224,000 | +17.4% | 52,525 | 0.0% | 0.22% | +10.1% | |
| TFX | Sell | Teleflex Incorporated | $6,195,000 | +5.5% | 15,052 | -12.8% | 0.22% | -0.9% |
| DNLI | New | Denali Therapeutics Inc. | $6,059,000 | – | 72,333 | +100.0% | 0.21% | – |
| RVNC | Buy | Revance Therapeutics, Inc. | $6,059,000 | +180.8% | 213,808 | +149.1% | 0.21% | +163.0% |
| COGT | New | Cogent Biosciences, Inc. | $6,039,000 | – | 537,742 | +100.0% | 0.21% | – |
| AMED | Amedisys, Inc. | $5,689,000 | +24.1% | 19,395 | 0.0% | 0.20% | +16.3% | |
| BCEL | Atreca, Inc. | $5,692,000 | +15.6% | 352,424 | 0.0% | 0.20% | +8.7% | |
| SRRK | New | Scholar Rock Holding Corporation | $5,634,000 | – | 116,094 | +100.0% | 0.20% | – |
| ALGN | Align Technology, Inc. | $5,366,000 | +63.2% | 10,041 | 0.0% | 0.19% | +53.7% | |
| PKI | Sell | PerkinElmer, Inc. | $5,323,000 | +10.2% | 37,094 | -3.6% | 0.19% | +3.3% |
| VRNA | Buy | Verona Pharma plcsponsored adr | $5,263,000 | +77.4% | 751,905 | +58.2% | 0.18% | +66.7% |
| FMTX | New | Forma Therapeutics Holdings, Inc.shares | $5,229,000 | – | 149,825 | +100.0% | 0.18% | – |
| ZLAB | Zai Lab Limitedadr | $5,078,000 | +62.7% | 37,523 | 0.0% | 0.18% | +52.1% | |
| CNC | Sell | Centene Corporation | $5,051,000 | -81.1% | 84,145 | -81.6% | 0.18% | -82.3% |
| RETA | Sell | Reata Pharmaceuticals, Inc.class a | $4,725,000 | -36.6% | 38,219 | -50.0% | 0.17% | -40.5% |
| PEAK | Healthpeak Properties, Inc. | $4,546,000 | +11.3% | 150,392 | 0.0% | 0.16% | +4.6% | |
| QURE | Buy | uniQure N.V.shares | $4,516,000 | +94.5% | 125,003 | +98.3% | 0.16% | +82.8% |
| NVO | Sell | Novo Nordisk A/Ssponsored adr | $4,534,000 | -51.3% | 64,906 | -51.6% | 0.16% | -54.4% |
| ADUS | Buy | Addus HomeCare Corporation | $4,407,000 | +192.0% | 37,640 | +135.7% | 0.16% | +171.9% |
| SNN | Smith & Nephew plcshares | $4,198,000 | +7.8% | 99,560 | 0.0% | 0.15% | +1.4% | |
| AMRN | Amarin Corporation PLCsponsored adr | $4,154,000 | +16.1% | 849,588 | 0.0% | 0.15% | +9.0% | |
| AUPH | Aurinia Pharmaceuticals Inc. | $4,157,000 | -6.1% | 300,611 | 0.0% | 0.15% | -12.0% | |
| PRAX | New | Praxis Precision Medicines, Inc. | $4,127,000 | – | 75,000 | +100.0% | 0.14% | – |
| AXNX | Buy | Axonics Modulation Technologies, Inc. | $4,032,000 | +307.3% | 80,760 | +316.3% | 0.14% | +283.8% |
| SNY | Sell | Sanofisponsored adr | $3,963,000 | -79.3% | 81,554 | -78.6% | 0.14% | -80.6% |
| ARDX | Ardelyx, Inc. | $3,932,000 | +23.3% | 607,698 | 0.0% | 0.14% | +15.0% | |
| TAK | Takeda Pharmaceutical Company Limitedsponsored ads | $3,825,000 | +2.0% | 210,146 | 0.0% | 0.13% | -4.3% | |
| ENDP | Endo International plcshares | $3,817,000 | +117.6% | 531,570 | 0.0% | 0.13% | +103.0% | |
| YMAB | Y-mAbs Therapeutics, Inc. | $3,790,000 | +29.0% | 76,548 | 0.0% | 0.13% | +20.9% | |
| PIRS | Pieris Pharmaceuticals, Inc. | $3,623,000 | +20.8% | 1,449,269 | 0.0% | 0.13% | +13.4% | |
| ABMD | Sell | ABIOMED, Inc. | $3,505,000 | +3.6% | 10,812 | -11.5% | 0.12% | -3.1% |
| DCPH | Deciphera Pharmaceuticals, Inc. | $3,502,000 | +11.2% | 61,370 | 0.0% | 0.12% | +4.2% | |
| ALKS | Alkermes plcshares | $3,390,000 | +20.4% | 169,930 | 0.0% | 0.12% | +12.3% | |
| THC | Sell | Tenet Healthcare Corporation | $3,304,000 | +39.4% | 82,736 | -14.5% | 0.12% | +30.3% |
| INSM | Insmed Incorporated | $3,275,000 | +3.6% | 98,387 | 0.0% | 0.12% | -2.5% | |
| HR | Healthcare Realty Trust Incorporated | $3,079,000 | -1.7% | 104,024 | 0.0% | 0.11% | -7.7% | |
| PHG | Koninklijke Philips N.V.ny reg sh | $3,084,000 | +14.9% | 56,927 | 0.0% | 0.11% | +6.9% | |
| NKTR | Sell | Nektar Therapeutics | $3,067,000 | -29.7% | 180,438 | -31.4% | 0.11% | -34.1% |
| KDMN | Kadmon Holdings, Inc. | $2,963,000 | +5.9% | 714,008 | 0.0% | 0.10% | -1.0% | |
| HRTX | Heron Therapeutics, Inc. | $2,776,000 | +42.8% | 131,183 | 0.0% | 0.10% | +34.2% | |
| HLXA | New | Helix Acquisition Corp. | $2,708,000 | – | 250,000 | +100.0% | 0.10% | – |
| ZYME | Zymeworks Inc. | $2,644,000 | +1.5% | 55,938 | 0.0% | 0.09% | -5.1% | |
| MEDP | Medpace Holdings, Inc. | $2,627,000 | +24.6% | 18,871 | 0.0% | 0.09% | +16.5% | |
| EIDX | Eidos Therapeutics, Inc. | $2,632,000 | +160.3% | 20,000 | 0.0% | 0.09% | +142.1% | |
| AXSM | Axsome Therapeutics, Inc. | $2,574,000 | +14.3% | 31,591 | 0.0% | 0.09% | +7.1% | |
| HOLX | Hologic, Inc. | $2,372,000 | +9.6% | 32,564 | 0.0% | 0.08% | +2.5% | |
| MOR | MorphoSys AGsponsored ads | $2,320,000 | -9.7% | 81,867 | 0.0% | 0.08% | -14.6% | |
| INGN | Inogen, Inc. | $2,297,000 | +54.1% | 51,406 | 0.0% | 0.08% | +44.6% | |
| PRGO | Perrigo Company plcshares | $2,291,000 | -2.6% | 51,224 | 0.0% | 0.08% | -8.0% | |
| GMRE | Global Medical REIT Inc. | $2,284,000 | -3.3% | 174,897 | 0.0% | 0.08% | -9.1% | |
| BHC | Sell | Bausch Health Companies Inc. | $2,109,000 | +14.6% | 101,412 | -14.4% | 0.07% | +7.2% |
| NCNA | NuCana plcsponsored adr | $2,068,000 | -13.2% | 460,672 | 0.0% | 0.07% | -18.0% | |
| MTEM | Molecular Templates, Inc. | $2,064,000 | -14.0% | 219,822 | 0.0% | 0.07% | -18.9% | |
| ALC | Sell | Alcon Inc.ordinary shares | $2,064,000 | -1.2% | 31,286 | -14.7% | 0.07% | -6.4% |
| HTA | Healthcare Trust of America, Inc. | $1,946,000 | +5.9% | 70,662 | 0.0% | 0.07% | -1.4% | |
| ICPT | Intercept Pharmaceuticals, Inc. | $1,904,000 | -40.4% | 77,067 | 0.0% | 0.07% | -44.2% | |
| ZGNX | Sell | Zogenix, Inc. | $1,779,000 | -70.2% | 88,977 | -73.3% | 0.06% | -71.9% |
| HARP | Harpoon Therapeutics, Inc. | $1,768,000 | -2.2% | 106,419 | 0.0% | 0.06% | -8.8% | |
| MIST | Buy | Milestone Pharmaceuticals Inc. | $1,699,000 | +8.8% | 253,610 | +18.9% | 0.06% | +3.4% |
| GRTS | New | Gritstone Oncology, Inc. | $1,651,000 | – | 419,005 | +100.0% | 0.06% | – |
| AFMD | New | Affimed N.V. | $1,560,000 | – | 268,019 | +100.0% | 0.06% | – |
| AVDL | Avadel Pharmaceuticals plcsponsored adr | $1,561,000 | +32.6% | 233,612 | 0.0% | 0.06% | +25.0% | |
| DRNA | Dicerna Pharmaceuticals, Inc. | $1,501,000 | +22.4% | 68,150 | 0.0% | 0.05% | +15.2% | |
| MGTA | Magenta Therapeutics, Inc. | $1,509,000 | +15.3% | 192,431 | 0.0% | 0.05% | +8.2% | |
| DHC | Diversified Healthcare Trust | $1,474,000 | +17.1% | 357,720 | 0.0% | 0.05% | +10.6% | |
| MDGL | Madrigal Pharmaceuticals, Inc. | $1,483,000 | -6.4% | 13,340 | 0.0% | 0.05% | -11.9% | |
| SNR | New Senior Investment Group Inc. | $1,328,000 | +29.4% | 256,398 | 0.0% | 0.05% | +23.7% | |
| ALLO | New | Allogene Therapeutics, Inc. | $1,214,000 | – | 48,089 | +100.0% | 0.04% | – |
| XLV | Health Care Select Sector SPDR Fundsbi healthcare | $1,141,000 | +7.5% | 10,055 | 0.0% | 0.04% | 0.0% | |
| ESPR | Esperion Therapeutics, Inc. | $1,081,000 | -30.0% | 41,577 | 0.0% | 0.04% | -34.5% | |
| IMGN | ImmunoGen, Inc. | $1,085,000 | +79.3% | 168,190 | 0.0% | 0.04% | +65.2% | |
| KPTI | Karyopharm Therapeutics Inc. | $1,018,000 | +6.0% | 65,743 | 0.0% | 0.04% | 0.0% | |
| BMYRT | Bristol Myers Squibb Companyright | $1,017,000 | -69.3% | 1,473,710 | 0.0% | 0.04% | -71.0% | |
| RGNX | REGENXBIO Inc. | $984,000 | +64.8% | 21,700 | 0.0% | 0.04% | +59.1% | |
| AERI | Aerie Pharmaceuticals, Inc. | $901,000 | +14.8% | 66,688 | 0.0% | 0.03% | +10.3% | |
| ACIU | AC Immune SAshares | $888,000 | +6.0% | 171,813 | 0.0% | 0.03% | 0.0% | |
| GRFS | Grifols, S.A.sponsored adr | $874,000 | +6.3% | 47,373 | 0.0% | 0.03% | 0.0% | |
| CYH | Community Health Systems, Inc. | $875,000 | +76.1% | 117,735 | 0.0% | 0.03% | +63.2% | |
| OVID | Ovid Therapeutics Inc.sponsored adr | $861,000 | -59.7% | 372,733 | 0.0% | 0.03% | -62.5% | |
| VYNE | VYNE Therapeutics Inc. | $856,000 | -4.8% | 541,584 | 0.0% | 0.03% | -11.8% | |
| CHCT | Community Healthcare Trust Incorporated | $702,000 | +0.7% | 14,900 | 0.0% | 0.02% | -3.8% | |
| UHT | Universal Health Realty Income Trustshares | $724,000 | +12.8% | 11,258 | 0.0% | 0.02% | +4.2% | |
| NHI | National Health Investors, Inc. | $694,000 | +14.7% | 10,038 | 0.0% | 0.02% | +4.3% | |
| ASRT | Assertio Holdings, Inc. | $587,000 | -46.3% | 1,642,302 | 0.0% | 0.02% | -48.8% | |
| CRBP | Corbus Pharmaceuticals Holdings, Inc. | $517,000 | -30.5% | 413,481 | 0.0% | 0.02% | -35.7% | |
| CBAY | CymaBay Therapeutics, Inc. | $506,000 | -20.7% | 88,102 | 0.0% | 0.02% | -25.0% | |
| CLSD | Clearside Biomedical, Inc. | $453,000 | +77.6% | 165,330 | 0.0% | 0.02% | +60.0% | |
| SPPI | Spectrum Pharmaceuticals, Inc. | $391,000 | -16.5% | 114,670 | 0.0% | 0.01% | -22.2% | |
| CLLS | Sell | Cellectissponsored adr | $324,000 | -84.1% | 11,955 | -89.1% | 0.01% | -85.5% |
| VTRS | New | Viatris Inc. | $251,000 | – | 13,400 | +100.0% | 0.01% | – |
| FVE | Five Star Senior Living Inc. | $167,000 | +35.8% | 24,237 | 0.0% | 0.01% | +20.0% | |
| ABIO | ARCA biopharma, Inc. | $130,000 | -9.1% | 32,461 | 0.0% | 0.01% | 0.0% | |
| CLDX | Celldex Therapeutics, Inc. | $124,000 | +18.1% | 7,053 | 0.0% | 0.00% | 0.0% | |
| Bellicum Pharmaceuticals, Inc. | $21,000 | -46.2% | 6,000 | 0.0% | 0.00% | 0.0% | ||
| Tetraphase Pharmaceuticals, Inc. | $9,000 | 0.0% | 42,965 | 0.0% | 0.00% | – | ||
| MNKKQ | Exit | Mallinckrodt plcsponsored adr | $0 | – | -32,980 | -100.0% | -0.00% | – |
| TCDA | Exit | Tricida, Inc. | $0 | – | -50,370 | -100.0% | -0.02% | – |
| GLPG | Exit | Galapagos NVsponsored adr | $0 | – | -6,543 | -100.0% | -0.04% | – |
| GSK | Exit | GlaxoSmithKline PLCshares | $0 | – | -32,400 | -100.0% | -0.05% | – |
| BHVN | Exit | Biohaven Pharmaceutical Holding Co. Ltd. | $0 | – | -34,277 | -100.0% | -0.08% | – |
| COGT | Exit | Cogent Biosciences, Inc. | $0 | – | -1,103,175 | -100.0% | -0.10% | – |
| MYOK | Exit | MyoKardia, Inc. | $0 | – | -19,300 | -100.0% | -0.10% | – |
| BNTX | Exit | BioNTech SEsponsored ads | $0 | – | -43,595 | -100.0% | -0.11% | – |
| CHRS | Exit | Coherus Biosciences, Inc. | $0 | – | -203,103 | -100.0% | -0.14% | – |
| ACHC | Exit | Acadia Healthcare Co., Inc. | $0 | – | -131,200 | -100.0% | -0.14% | – |
| GBT | Exit | Global Blood Therapeutics, Inc. | $0 | – | -71,759 | -100.0% | -0.15% | – |
| BLUE | Exit | bluebird bio, Inc. | $0 | – | -84,194 | -100.0% | -0.17% | – |
| CERN | Exit | Cerner Corp. | $0 | – | -81,500 | -100.0% | -0.22% | – |
| AGIO | Exit | Agios Pharmaceuticals, Inc. | $0 | – | -186,964 | -100.0% | -0.24% | – |
| ABC | Exit | AmerisourceBergen Corp. | $0 | – | -80,645 | -100.0% | -0.29% | – |
| BAX | Exit | Baxter International Inc. | $0 | – | -122,023 | -100.0% | -0.37% | – |
| MYL | Exit | Mylan N.V.shares | $0 | – | -1,010,754 | -100.0% | -0.56% | – |
| IMMU | Exit | Immunomedics, Inc. | $0 | – | -223,336 | -100.0% | -0.71% | – |
| SGEN | Exit | Seagen Inc. | $0 | – | -337,204 | -100.0% | -2.47% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2021-02-12
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| Gilead Sciences, Inc. | 41 | Q2 2023 | 12.4% |
| Amgen, Inc. | 41 | Q2 2023 | 5.8% |
| Biogen Inc. | 41 | Q2 2023 | 6.5% |
| Vertex Pharmaceuticals Incorporated | 41 | Q2 2023 | 5.3% |
| Regeneron Pharmaceuticals, Inc. | 41 | Q2 2023 | 9.1% |
| Illumina, Inc. | 41 | Q2 2023 | 3.4% |
| BioMarin Pharmaceutical Inc. | 41 | Q2 2023 | 2.9% |
| Teva Pharmaceutical Industries Ltd. | 41 | Q2 2023 | 3.2% |
| Neurocrine Biosciences, Inc. | 41 | Q2 2023 | 1.4% |
| McKesson Corporation | 41 | Q2 2023 | 2.2% |
View Tekla Capital Management LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Rallybio Corp | January 23, 2023 | 1,727,067 | 4.6% |
| Zyla Life SciencesSold out | January 29, 2021 | 0 | 0.0% |
| ARCA biopharma, Inc. | January 24, 2020 | 36,068 | 2.3% |
| Verona Pharma plc | February 12, 2019 | 5,296,845 | 4.9% |
| Alliqua BioMedical, Inc. | February 12, 2018 | 165,000 | 3.3% |
| PIERIS PHARMACEUTICALS, INC. | February 12, 2018 | 1,962,380 | 4.4% |
| Intellipharmaceutics International Inc. | February 13, 2015 | 2,184,000 | 9.0% |
| HERON THERAPEUTICS, INC. /DE/ | February 14, 2014 | 20,598,613 | 4.2% |
| MEDWAVE INC | February 14, 2012 | 1,277,372 | 9.8% |
| MZT Holdings, Inc. | February 14, 2012 | 2,553,420 | 4.0% |
View Tekla Capital Management LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2023-08-10 |
| 13F-HR | 2023-05-10 |
| 13F-HR | 2023-02-10 |
| SC 13G/A | 2023-01-23 |
| 13F-HR | 2022-11-01 |
| 13F-HR | 2022-07-29 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-14 |
| SC 13G | 2022-01-21 |
| 13F-HR | 2021-11-12 |
View Tekla Capital Management LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.