$450 Million is the total value of GREAT POINT PARTNERS LLC's 36 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 83.3% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ARNA | ARENA PHARMACEUTICALS INC | $49,320,000 | +56.1% | 530,670 | 0.0% | 10.96% | +48.9% | |
| EXEL | Buy | EXELIXIS INC | $31,990,000 | -0.8% | 1,750,000 | +14.8% | 7.11% | -5.3% |
| XENE | Buy | XENON PHARMACEUTICALS INC | $29,678,000 | +177.5% | 950,000 | +35.7% | 6.59% | +164.8% |
| TVTX | Buy | TRAVERE THERAPEUTICS INC | $24,832,000 | +63.8% | 800,000 | +28.0% | 5.52% | +56.3% |
| ANAB | Buy | ANAPTYSBIO INC | $20,581,000 | +38.1% | 592,250 | +7.8% | 4.57% | +31.8% |
| VRTX | VERTEX PHARMACEUTICALS INC | $18,666,000 | +21.1% | 85,000 | 0.0% | 4.15% | +15.5% | |
| BCAB | Buy | BIOATLA INC | $16,966,000 | -31.7% | 864,300 | +2.4% | 3.77% | -34.8% |
| GLPG | New | GALAPAGOS NVspon adr | $16,539,000 | – | 300,000 | +100.0% | 3.67% | – |
| RLMD | New | RELMADA THERAPEUTICS INC | $16,161,000 | – | 717,320 | +100.0% | 3.59% | – |
| MGNX | MACROGENICS INC | $16,050,000 | -23.4% | 1,000,000 | 0.0% | 3.57% | -26.9% | |
| CYTK | Sell | CYTOKINETICS INC | $15,953,000 | +14.0% | 350,000 | -10.6% | 3.54% | +8.8% |
| TCDA | Sell | TRICIDA INC | $13,384,000 | +46.1% | 1,400,000 | -29.1% | 2.97% | +39.4% |
| RIGL | Buy | RIGEL PHARMACEUTICALS INC | $13,250,000 | +84.4% | 5,000,000 | +152.5% | 2.94% | +76.0% |
| SRPT | New | SAREPTA THERAPEUTICS INC | $13,094,000 | – | 145,405 | +100.0% | 2.91% | – |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $12,174,000 | – | 200,000 | +100.0% | 2.70% | – |
| PCVX | Buy | VAXCYTE INC | $11,895,000 | +378.1% | 500,000 | +409.9% | 2.64% | +356.5% |
| RNA | New | AVIDITY BIOSCIENCES INC | $11,885,000 | – | 500,000 | +100.0% | 2.64% | – |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $11,632,000 | +29.2% | 800,000 | +60.0% | 2.58% | +23.3% |
| RCKT | Sell | ROCKET PHARMACEUTICALS INC | $10,926,000 | -52.2% | 500,526 | -34.6% | 2.43% | -54.4% |
| SLN | New | SILENCE THERAPEUTICS PLCads | $10,618,000 | – | 444,443 | +100.0% | 2.36% | – |
| DYN | Buy | DYNE THERAPEUTICS INC | $10,047,000 | -17.0% | 845,000 | +13.4% | 2.23% | -20.8% |
| PASG | New | PASSAGE BIO INC | $9,640,000 | – | 1,518,095 | +100.0% | 2.14% | – |
| PRQR | Buy | PROQR THRAPEUTICS N V | $8,980,000 | +3435.4% | 1,121,122 | +3595.7% | 2.00% | +3281.4% |
| URGN | Buy | UROGEN PHARMA LTD | $8,306,000 | -34.2% | 873,424 | +16.5% | 1.84% | -37.2% |
| KDNY | New | CHINOOK THERAPEUTICS INC | $6,362,000 | – | 390,041 | +100.0% | 1.41% | – |
| KNSA | Buy | KINIKSA PHARMACEUTICALS LTD | $6,317,000 | +15.5% | 536,738 | +11.8% | 1.40% | +10.2% |
| PIRS | New | PIERIS PHARMACEUTICALS INC | $5,859,000 | – | 1,550,000 | +100.0% | 1.30% | – |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $5,450,000 | – | 411,937 | +100.0% | 1.21% | – |
| MGTA | MAGENTA THERAPEUTICS INC | $5,183,000 | -39.2% | 1,170,000 | 0.0% | 1.15% | -42.0% | |
| New | PYXIS ONCOLOGY INC | $4,388,000 | – | 400,000 | +100.0% | 0.98% | – | |
| AGLE | Buy | AEGLEA BIOTHERAPEUTICS INC | $4,324,000 | -39.6% | 910,251 | +1.1% | 0.96% | -42.3% |
| NKTR | New | NEKTAR THERAPEUTICScall | $2,755,000 | – | 203,900 | +100.0% | 0.61% | – |
| ABUS | New | ARBUTUS BIOPHARMA CORP | $2,602,000 | – | 668,907 | +100.0% | 0.58% | – |
| CABA | New | CABALETTA BIO INC | $1,791,000 | – | 472,433 | +100.0% | 0.40% | – |
| RFL | RAFAEL HLDGS INC | $1,457,000 | -83.4% | 285,714 | 0.0% | 0.32% | -84.1% | |
| PNT | New | POINT BIOPHARMA GLOBAL INC | $1,067,000 | – | 190,520 | +100.0% | 0.24% | – |
| IFRX | Exit | INFLARX NV | $0 | – | -551,918 | -100.0% | -0.33% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -249,000 | -100.0% | -0.55% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -121,342 | -100.0% | -0.56% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -93,137 | -100.0% | -0.57% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INCcall | $0 | – | -200,000 | -100.0% | -1.54% | – |
| PHAT | Exit | PHATHOM PHARMACEUTICALS INC | $0 | – | -220,863 | -100.0% | -1.65% | – |
| CTMX | Exit | CYTOMX THERAPEUTICS INC | $0 | – | -1,500,000 | -100.0% | -1.78% | – |
| NKTR | Exit | NEKTAR THERAPEUTICS | $0 | – | -504,691 | -100.0% | -2.11% | – |
| OLMA | Exit | OLEMA PHARMACEUTICALS INC | $0 | – | -329,086 | -100.0% | -2.11% | – |
| PBYI | Exit | PUMA BIOTECHNOLOGY INC | $0 | – | -1,300,000 | -100.0% | -2.12% | – |
| SAGE | Exit | SAGE THERAPEUTICS INC | $0 | – | -269,010 | -100.0% | -2.78% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -47,500 | -100.0% | -3.13% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -86,667 | -100.0% | -3.72% | – |
| DRNA | Exit | DICERNA PHARMACEUTICALS INC | $0 | – | -799,999 | -100.0% | -3.76% | – |
| KDMN | Exit | KADMON HLDGS INC | $0 | – | -3,375,000 | -100.0% | -6.84% | – |
Other managers
Other managers that, in addition to the filing manager(s), that filed the EDGAR filing(s):
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-14
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| STREAMLINE HEALTH SOLUTNS, INC CMN | 25 | Q3 2019 | 2.5% |
| IOVANCE BIOTHERAPEUTICS, INC. CMN | 16 | Q1 2021 | 14.3% |
| ZOGENIX INC CMN | 16 | Q4 2019 | 8.8% |
| PTC THERAPEUTICS, INC. CMN | 16 | Q3 2023 | 9.9% |
| EXELIXIS, INC | 16 | Q1 2022 | 7.5% |
| SAGE THERAPEUTICS, INC CMN | 15 | Q3 2021 | 10.8% |
| CYTOKINETICS INC | 15 | Q3 2023 | 5.8% |
| ACADIA PHARMACEUTICALS, INC. | 14 | Q1 2021 | 8.8% |
| ACCELERON PHARMA INC CMN | 14 | Q2 2020 | 8.2% |
| CONNECTURE INC | 13 | Q4 2017 | 25.1% |
View GREAT POINT PARTNERS LLC's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| 89bio, Inc. | February 14, 2023 | 700,000 | 1.4% |
| KalVista Pharmaceuticals, Inc. | February 14, 2023 | 1,055,801 | 3.1% |
| Avalo Therapeutics, Inc. | February 13, 2023 | 974,639 | 7.1% |
| InflaRx N.V.Sold out | February 14, 2022 | 0 | 0.0% |
| ABEONA THERAPEUTICS INC.Sold out | February 16, 2021 | 0 | 0.0% |
| CONSTELLATION PHARMACEUTICALS INC | February 16, 2021 | 1,024,800 | 2.2% |
| GERON CORP | February 16, 2021 | 12,754,228 | 4.0% |
| Millendo Therapeutics, Inc. | February 16, 2021 | 270,000 | 1.4% |
| NextCure, Inc.Sold out | February 16, 2021 | 0 | 0.0% |
| PROTHENA CORP PUBLIC LTD CO | February 16, 2021 | 977,647 | 2.4% |
View GREAT POINT PARTNERS LLC's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| SC 13G | 2024-04-08 |
| 13F-HR | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
| SC 13G/A | 2024-02-14 |
View GREAT POINT PARTNERS LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.