Baker Brothers Advisors - Q3 2016 holdings

$11 Billion is the total value of Baker Brothers Advisors's 134 reported holdings in Q3 2016. The portfolio turnover from Q2 2016 to Q3 2016 was 15.6% .

 Value Shares↓ Weighting
SGEN BuySeattle Genetics, Inc.$2,381,857,000
+36.3%
44,100,294
+2.0%
21.61%
+18.0%
INCY BuyIncyte Corporation$2,215,711,000
+17.9%
23,498,898
+0.0%
20.11%
+2.0%
ABBV SellAbbVie Inc.$904,636,000
+1.7%
14,343,358
-0.2%
8.21%
-12.0%
ACAD BuyACADIA Pharmaceuticals Inc.$821,327,000
+3.2%
25,819,768
+5.3%
7.45%
-10.7%
ALXN  Alexion Pharmaceuticals, Inc.$801,815,000
+5.0%
6,543,2950.0%7.28%
-9.2%
 Incyte Corporation Notes 1.25% 11/15/2020 144Anote 1.25% 11/15/2020$531,244,000
+13.7%
274,500,0000.0%4.82%
-1.6%
 Incyte Corporation Notes 0.375% 11/15/2018 144Anote 0.375% 11/15/2018$491,344,000
+13.8%
259,000,0000.0%4.46%
-1.5%
BMRN  BioMarin Pharmaceutical Inc.$444,696,000
+18.9%
4,806,4830.0%4.04%
+2.9%
GHDX BuyGenomic Health, Inc.$398,237,000
+12.5%
13,770,302
+0.7%
3.61%
-2.6%
DBVT  DBV Technologies S.A.sponsored adr$200,162,000
+11.4%
5,509,5600.0%1.82%
-3.6%
AQXP BuyAquinox Pharmaceuticals, Inc.$140,762,000
+174.3%
10,536,092
+35.9%
1.28%
+137.4%
 BioMarin Pharmaceutical Inc. Notes 1.875% 4/23/2017note 1.875% 4/23/2017$101,405,000
+19.4%
22,379,0000.0%0.92%
+3.4%
BLCM  Bellicum Pharmaceuticals, Inc.$96,826,000
+53.5%
4,865,6470.0%0.88%
+33.0%
CERS SellCerus Corporation$81,061,000
-4.2%
13,053,275
-3.7%
0.74%
-17.0%
ONCE  Spark Therapeutics, Inc.$79,180,000
+17.5%
1,318,3410.0%0.72%
+1.7%
ACOR  Acorda Therapeutics, Inc.$76,443,000
-18.1%
3,661,0820.0%0.69%
-29.1%
 Clovis Oncology, Inc. 2.5% 9/15/2021note 2.5% 9/15/2021$69,135,000
+34.7%
72,758,0000.0%0.63%
+16.5%
AMRN BuyAmarin Corporation plcsponsored adr new$65,811,000
+3699.7%
20,630,477
+2472.8%
0.60%
+3216.7%
EXEL BuyExelixis, Inc.$63,048,000
+212.9%
4,929,494
+91.1%
0.57%
+171.1%
 Acorda Therapeutics, Inc. Notes 1.75% 6/15/2021note 1.75% 6/15/2021$62,830,000
-6.7%
77,083,0000.0%0.57%
-19.3%
BGNE  BeiGene, Ltd.sponsored adr$58,930,000
+3.4%
1,912,6800.0%0.54%
-10.5%
NVTA  Invitae Corporation$57,422,000
+18.5%
6,554,9670.0%0.52%
+2.6%
HRTX  Heron Therapeutics, Inc.$49,230,000
-4.5%
2,857,2500.0%0.45%
-17.4%
BCRX SellBioCryst Pharmaceuticals, Inc.$48,351,000
+13.4%
10,963,944
-27.0%
0.44%
-1.8%
NBIX  Neurocrine Biosciences, Inc.$45,344,000
+11.4%
895,4220.0%0.41%
-3.7%
AAAP BuyAdvanced Accelerator Applications S.A.sponsored adr$39,194,000
+55.6%
1,029,247
+23.5%
0.36%
+34.8%
VSAR SellVersartis, Inc.$26,145,000
-13.2%
2,134,247
-21.6%
0.24%
-25.0%
PGNX SellProgenics Pharmaceuticals, Inc.$23,110,000
+37.9%
3,650,808
-8.0%
0.21%
+19.3%
FOMX BuyFoamix Pharmaceuticals Ltd.$22,842,000
+60.5%
2,466,702
+10.0%
0.21%
+38.9%
ARRY SellArray BioPharma Inc.$22,347,000
+45.6%
3,310,666
-23.2%
0.20%
+26.1%
XNCR  Xencor, Inc.$21,357,000
+29.0%
872,0720.0%0.19%
+11.5%
HALO SellHalozyme Therapeutics, Inc.$20,911,000
+31.8%
1,731,057
-5.8%
0.19%
+14.5%
ACHN  Achillion Pharmaceuticals, Inc.$20,052,000
+3.8%
2,475,5150.0%0.18%
-9.9%
BLUE  bluebird bio, Inc.$19,923,000
+56.6%
293,9430.0%0.18%
+36.1%
MRUS BuyMerus N.V.$19,430,000
+116.6%
1,160,014
+3.3%
0.18%
+87.2%
SGMO  Sangamo BioSciences, Inc.$18,779,000
-20.0%
4,055,8760.0%0.17%
-30.9%
NTLA  Intellia Therapeutics, Inc.$18,077,000
-20.3%
1,062,1200.0%0.16%
-31.1%
IDRA BuyIdera Pharmaceuticals, Inc.$17,956,000
+67.6%
7,014,015
+0.2%
0.16%
+45.5%
DSCI  Derma Sciences, Inc.$17,524,000
+18.5%
3,752,3900.0%0.16%
+2.6%
 Aegerion Pharmaceuticals, Inc. Notes 2.0% 8/15/2019note 2.0% 8/15/2019$17,432,000
+17.5%
26,517,0000.0%0.16%
+1.3%
GLPG  Galapagos NVsponsored adr$16,805,000
+16.6%
259,8940.0%0.15%
+0.7%
TGTX  TG Therapeutics, Inc.$15,511,000
+27.7%
2,003,9910.0%0.14%
+11.0%
ASND  Ascendis Pharma A/Ssponsored adr$14,985,000
+51.5%
745,5210.0%0.14%
+30.8%
MRTX  Mirati Therapeutics, Inc.$14,999,000
+21.1%
2,269,1980.0%0.14%
+4.6%
 BioMarin Pharmaceutical Inc. Notes 0.75% 10/15/2018note 0.75% 10/15/2018$14,630,000
+7.8%
12,228,0000.0%0.13%
-6.3%
ARWR BuyArrowhead Pharmaceuticals, Inc.$13,649,000
+154.1%
1,856,967
+83.9%
0.12%
+121.4%
VTAE  Vitae Pharmaceuticals, Inc.$13,339,000
+93.9%
637,5970.0%0.12%
+68.1%
ALKS  Alkermes plc$11,769,000
+8.8%
250,2510.0%0.11%
-5.3%
ZGNX  Zogenix, Inc.$11,430,000
+42.0%
1,000,0000.0%0.10%
+23.8%
AERI  Aerie Pharmaceuticals, Inc.$11,298,000
+114.4%
299,3560.0%0.10%
+87.3%
DERM  Dermira, Inc.$11,040,000
+15.6%
326,4280.0%0.10%0.0%
AGIO  Agios Pharmaceuticals, Inc.$10,982,000
+26.1%
207,9150.0%0.10%
+9.9%
MGNX  MacroGenics, Inc.$10,878,000
+10.8%
363,6760.0%0.10%
-3.9%
AIMT  Aimmune Therapeutics, Inc.$10,109,000
+38.6%
673,9080.0%0.09%
+21.1%
CFRX NewContraFect Corporation$10,034,0004,045,876
+100.0%
0.09%
DMTX  Dimension Therapeutics, Inc.$10,003,000
+33.2%
1,251,8810.0%0.09%
+15.2%
SAGE SellSage Therapeutics, Inc.$9,594,000
+42.1%
208,328
-7.0%
0.09%
+22.5%
ITCI  Intra-Cellular Therapies, Inc.$9,284,000
-60.7%
609,1660.0%0.08%
-66.1%
IMGN  ImmunoGen, Inc.$8,081,000
-13.0%
3,015,3530.0%0.07%
-24.7%
LGND  Ligand Pharmaceuticals Incorporated$7,490,000
-14.4%
73,3860.0%0.07%
-26.1%
ALDR  Alder BioPharmaceuticals, Inc.$7,122,000
+31.2%
217,3280.0%0.06%
+14.0%
RARE SellUltragenyx Pharmaceutical Inc.$7,094,000
+30.8%
100,000
-9.8%
0.06%
+12.3%
NewInotek Pharmaceuticals Corporation Notes 5.75% 8/1/2021note 5.75% 8/1/2021$6,708,0005,000,000
+100.0%
0.06%
BuyTrillium Therapeutics Inc.$6,120,000
+221.8%
413,697
+95.3%
0.06%
+180.0%
INSM SellInsmed Incorporated$5,808,000
-60.7%
400,000
-73.3%
0.05%
-65.8%
ADHD  Alcobra Ltd.$5,771,000
-45.0%
2,336,3590.0%0.05%
-52.7%
PRQR SellProQR Therapeutics N.V.$5,739,000
-3.9%
860,464
-30.3%
0.05%
-17.5%
 NeuroDerm Ltd.$5,639,000
+13.8%
305,0000.0%0.05%
-1.9%
CPRX SellCatalyst Pharmaceuticals, Inc.$5,561,000
+52.9%
5,102,153
-0.4%
0.05%
+31.6%
MDGN  Medgenics, Inc.$4,905,000
+0.4%
880,5390.0%0.04%
-11.8%
NTRA  Natera, Inc.$5,000,000
-7.9%
450,0000.0%0.04%
-21.1%
AKTX  Akari Therapeutics plcsponsored adr$4,229,000
-36.9%
496,9010.0%0.04%
-45.7%
LOXO  Loxo Oncology, Inc.$3,606,000
+12.9%
137,7350.0%0.03%0.0%
NERV SellMinerva Neurosciences, Inc.$3,653,000
-29.6%
258,805
-49.1%
0.03%
-38.9%
RXDX  Ignyta, Inc.$3,592,000
+16.1%
571,0000.0%0.03%
+3.1%
STML  Stemline Therapeutics, Inc.$3,612,000
+60.0%
333,4970.0%0.03%
+37.5%
 Array BioPharma Inc. Notes 3.0% 6/1/2020note 3.0% 6/1/2020$3,561,000
+40.0%
3,000,0000.0%0.03%
+18.5%
CNCE SellConcert Pharmaceuticals, Inc.$3,205,000
-39.3%
316,976
-32.6%
0.03%
-47.3%
SNSS NewSunesis Pharmaceuticals, Inc.$3,241,000741,665
+100.0%
0.03%
TRVN  Trevena, Inc.$3,038,000
+7.2%
450,0000.0%0.03%
-6.7%
SYRS  Syros Pharmaceuticals, Inc.$2,836,000
-23.6%
204,4650.0%0.03%
-33.3%
ADMS  Adamas Pharmaceuticals, Inc.$2,833,000
+8.4%
172,6300.0%0.03%
-3.7%
NVIV  InVivo Therapeutics Holdings Corp.$2,720,000
+17.6%
400,0000.0%0.02%
+4.2%
GLYC  GlycoMimetics, Inc.$2,726,000
-1.7%
381,2350.0%0.02%
-13.8%
PRTO  Proteon Therapeutics, Inc.$2,786,000
+16.2%
298,5910.0%0.02%0.0%
ECYT SellEndocyte, Inc.$2,685,000
-26.0%
868,983
-23.1%
0.02%
-36.8%
AGLE  Aeglea BioTherapeutics, Inc.$2,591,000
+31.9%
404,2300.0%0.02%
+14.3%
SELB  Selecta Biosciences, Inc.$2,550,000
+1.8%
178,9500.0%0.02%
-11.5%
OSIR  Osiris Therapeutics, Inc.$2,476,000
-2.6%
499,1930.0%0.02%
-18.5%
JUNO  Juno Therapeutics, Inc.$2,401,000
-21.9%
80,0000.0%0.02%
-31.2%
NBRV  Nabriva Therapeutics AGsponsored adr$2,468,000
-6.0%
350,0000.0%0.02%
-21.4%
 Protalix BioTherapeutics, Inc. Notes 4.5% 9/15/18note 4.5% 9/15/2018$2,294,000
-0.3%
3,423,0000.0%0.02%
-12.5%
EPZM  Epizyme, Inc.$2,288,000
-3.9%
232,4810.0%0.02%
-16.0%
KPTI  Karyopharm Therapeutics Inc.$2,111,000
+45.0%
216,9900.0%0.02%
+26.7%
IONS  Ionis Pharmaceuticals, Inc.$2,094,000
+57.3%
57,1400.0%0.02%
+35.7%
ENTA  Enanta Pharmaceuticals, Inc.$2,005,000
+20.6%
75,3570.0%0.02%
+5.9%
MDWD  MediWound Ltd.$1,740,000
-2.4%
226,0000.0%0.02%
-15.8%
QURE  uniQure N.V.$1,760,000
+3.8%
230,0000.0%0.02%
-11.1%
ASMB  Assembly Biosciences, Inc.$1,803,000
+29.9%
250,0000.0%0.02%
+6.7%
SCYX  SCYNEXIS, Inc.$1,810,000
+78.3%
467,6000.0%0.02%
+45.5%
MYOK NewMyoKardia, Inc.$1,634,000100,000
+100.0%
0.02%
OPHT  Ophthotech Corporation$1,644,000
-9.6%
35,6490.0%0.02%
-21.1%
MCRB  Seres Therapeutics, Inc.$1,536,000
-57.7%
125,0000.0%0.01%
-63.2%
PTN  Palatin Technologies, Inc.$1,289,000
+42.4%
2,050,0000.0%0.01%
+33.3%
CLLS  Cellectis S.A.sponsored ads$1,204,000
-9.5%
50,0000.0%0.01%
-21.4%
AFMD  Affimed N.V.$1,112,000
+12.1%
400,0000.0%0.01%0.0%
IMDZ  Immune Design Corp.$1,129,000
-7.1%
148,9370.0%0.01%
-23.1%
FLGT NewFulgent Genetics, Inc.$1,153,000125,000
+100.0%
0.01%
ALDX  Aldeyra Therapeutics, Inc.$1,110,000
+37.4%
142,0000.0%0.01%
+25.0%
CLCD NewCoLucid Pharmaceuticals, Inc.$1,156,00030,310
+100.0%
0.01%
TENX  Tenax Therapeutics, Inc.$972,000
-9.6%
420,0000.0%0.01%
-18.2%
FPRX  Five Prime Therapeutics, Inc.$1,010,000
+26.9%
19,2470.0%0.01%
+12.5%
MSTX BuyMast Therapeutics, Inc.$944,000
-48.1%
8,584,051
+121.9%
0.01%
-52.6%
XLRN  Acceleron Pharma Inc.$1,041,000
+6.6%
28,7650.0%0.01%
-10.0%
INFI NewInfinity Pharmaceuticals, Inc.$905,000580,400
+100.0%
0.01%
NewAptose Biosciences Inc.$909,000404,211
+100.0%
0.01%
ALNY  Alnylam Pharmaceuticals, Inc.$769,000
+22.3%
11,3400.0%0.01%0.0%
DVAX  Dynavax Technologies Corporation$787,000
-28.1%
75,0000.0%0.01%
-36.4%
MDGL NewMadrigal Pharmaceuticals, Inc.$732,00057,762
+100.0%
0.01%
ABEO NewAbeona Therapeutics Inc.$610,000101,680
+100.0%
0.01%
ABUS  Arbutus Biopharma Corporation$621,000
-1.1%
180,5820.0%0.01%
-14.3%
RTTR  Ritter Pharmaceuticals, Inc.$672,000
+9.8%
400,0000.0%0.01%0.0%
WINT  Windtree Therapeutics, Inc.$653,000
+32.7%
254,9730.0%0.01%
+20.0%
CMRX  Chimerix, Inc.$638,000
+40.8%
115,2160.0%0.01%
+20.0%
ADAP  Adaptimmune Therapeutics plcsponsored adr$705,000
-13.5%
100,0000.0%0.01%
-33.3%
BDSI  BioDelivery Sciences International, Inc.$567,000
+14.3%
210,0210.0%0.01%0.0%
CYTR  CytRx Corporation$388,000
-73.6%
659,9950.0%0.00%
-73.3%
AKAOQ  Achaogen, Inc.$479,000
+26.4%
100,0000.0%0.00%0.0%
FMI  Foundation Medicine, Inc.$488,000
+25.1%
20,8920.0%0.00%0.0%
CCXI  ChemoCentryx, Inc.$296,000
+34.5%
49,0640.0%0.00%
+50.0%
LJPC  La Jolla Pharmaceutical Company$327,000
+48.6%
13,7460.0%0.00%
+50.0%
DNAI  ProNAi Therapeutics, Inc.$364,000
-8.5%
200,0000.0%0.00%
-25.0%
CYCCP  Cyclacel Pharmaceuticals, Inc.pfd conv ex 6%$90,000
+8.4%
13,2530.0%0.00%0.0%
BTXWS  BioTime, Inc.*w exp 10/1/201$17,000
+88.9%
20,0840.0%0.00%
SNTA ExitSynta Pharmaceuticals Corp.$0-2,021,728
-100.0%
-0.01%
GWPH ExitGW Pharmaceuticals plcads$0-15,000
-100.0%
-0.01%
AUPH ExitAurinia Pharmaceuticals Inc.$0-711,499
-100.0%
-0.02%
SNSS ExitSunesis Pharmaceuticals, Inc.$0-4,450,000
-100.0%
-0.03%
CRIS ExitCuris, Inc.$0-1,999,303
-100.0%
-0.03%
ExitCorsicanto Ltd. 3.5% 1/15/2032note 3.5% 1/15/2032$0-15,000,000
-100.0%
-0.16%
NVAX ExitNovavax, Inc.$0-2,379,254
-100.0%
-0.18%
MDVN ExitMedivation, Inc.$0-329,876
-100.0%
-0.21%
XNPT ExitXenoPort, Inc.$0-3,475,672
-100.0%
-0.26%
ExitExelixis, Inc. Notes 4.25% 8/15/2019note 4.25% 8/15/2019$0-20,000,000
-100.0%
-0.31%
ExitXenoPort, Inc. Notes 2.5% 2/1/2022note 2.5% 2/1/2022$0-100,000,000
-100.0%
-1.03%
Original filings

The following EDGAR filing(s) were analyzed to create this report:

  • View 13F-HR filed 2016-11-14
Signatures

The EDGAR filing(s) were signed by:

About Baker Brothers Advisors

Baker Brothers Advisors is a well-known investment management firm that specializes in the healthcare sector. The firm was founded in 2000 by brothers Julian and Felix Baker, who are both highly respected in the industry. Julian Baker is the CEO of the firm, while Felix Baker serves as a managing partner.

Baker Brothers Advisors has a reputation for investing in innovative healthcare companies that have the potential to make a significant impact on the industry. The firm has a long-term investment approach and is known for taking large positions in companies that it believes in. Some of the firm's most successful investments include companies such as Pharmacyclics, which was acquired by AbbVie for $21 billion, and Ariad Pharmaceuticals, which was acquired by Takeda for $5.2 billion.

The firm's investment strategy is led by its Chief Investment Officer, Dr. Robert Duggan, who has a background in both medicine and finance. Dr. Duggan is known for his ability to identify promising healthcare companies and for his willingness to take risks on early-stage companies.

Overall, Baker Brothers Advisors is a highly respected investment management firm that has a proven track record of success in the healthcare sector. While the firm's investment approach may not be suitable for all investors, those who are interested in the healthcare sector may want to consider Baker Brothers Advisors as a potential investment opportunity.

It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.

Top long-term holdings
NameQuarters ownedLatest quarter ownedMax weighting
Incyte Corporation42Q3 202337.6%
ACADIA Pharmaceuticals Inc.42Q3 202310.9%
Biomarin Pharmaceuticals Inc.42Q3 20235.9%
BioCryst Pharmaceuticals, Inc.42Q3 20231.7%
Cerus Corporation42Q3 20230.9%
Insmed Incorporated42Q3 20230.4%
Mirati Therapeutics, Inc.41Q3 20231.8%
Bluebird Bio Inc.41Q3 20230.3%
Heron Therapeutics, Inc.39Q3 20231.5%
ChemoCentryx, Inc.37Q3 20220.6%

View Baker Brothers Advisors's complete holdings history.

Latest significant ownerships (13-D/G)
Baker Brothers Advisors Q3 2016 significant holdings filed using form 13D/G when ownership exceeds 5% of a company's total stock issue.
FiledShares Percentage
Neoleukin Therapeutics, Inc.August 17, 20239,469,83820.0%
Mereo Biopharma Group plcAugust 10, 202314,604,3912.2%
Verastem, Inc.August 10, 2023? ?
TScan Therapeutics, Inc.June 02, 20232,793,9386.5%
ACADIA PHARMACEUTICALS INCMay 24, 202343,084,28026.5%
INCYTE CORPMarch 15, 202336,280,96716.3%
Seagen Inc.March 13, 202346,985,65625.1%
Talis Biomedical CorpMarch 10, 202337,569,14066.2%
Aeglea BioTherapeutics, Inc.February 14, 20236,384,0139.9%
Merus N.V.February 14, 2023? ?

View Baker Brothers Advisors's complete significant-ownership history.

Latest filings
TypeFiled
42024-04-23
SC 13D/A2024-04-23
42024-04-22
32024-04-18
SC 13D2024-04-18
32024-04-01
42024-04-01
42024-04-01
42024-04-01
SC 13D2024-04-01

View Baker Brothers Advisors's complete filings history.

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