| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| OMIC | Exit | SINGULAR GENOMICS SYSTEMS IN | $0 | – | -540,697 | -100.0% | -0.00% | – |
| Exit | HARPOON THERAPEUTICS INC | $0 | – | -62,121 | -100.0% | -0.01% | – | |
| ALT | Exit | ALTIMMUNE INC | $0 | – | -100,000 | -100.0% | -0.01% | – |
| XNCR | Exit | XENCOR INC | $0 | – | -19,142 | -100.0% | -0.01% | – |
| GLTO | Exit | GALECTO INC | $0 | – | -924,788 | -100.0% | -0.01% | – |
| Exit | CALCIMEDICA INC | $0 | – | -297,380 | -100.0% | -0.02% | – | |
| HRTX | Exit | HERON THERAPEUTICS INC | $0 | – | -802,700 | -100.0% | -0.02% | – |
| ELEV | Exit | ELEVATION ONCOLOGY INC | $0 | – | -1,500,000 | -100.0% | -0.02% | – |
| Exit | SYNLOGIC INC | $0 | – | -401,998 | -100.0% | -0.02% | – | |
| TARA | Exit | PROTARA THERAPEUTICS INC | $0 | – | -772,584 | -100.0% | -0.03% | – |
| IMTX | Exit | IMMATICS N.Vcall | $0 | – | -125,000 | -100.0% | -0.03% | – |
| PHGE | Exit | BIOMX INC | $0 | – | -4,553,489 | -100.0% | -0.03% | – |
| BOLT | Exit | BOLT BIOTHERAPEUTICS INC | $0 | – | -1,541,000 | -100.0% | -0.03% | – |
| BCAB | Exit | BIOATLA INC | $0 | – | -1,009,279 | -100.0% | -0.04% | – |
| AFIB | Exit | ACUTUS MED INC | $0 | – | -2,648,386 | -100.0% | -0.04% | – |
| CMMB | Exit | CHEMOMAB THERAPEUTICS LTDsponsored ads | $0 | – | -2,241,274 | -100.0% | -0.04% | – |
| TDOC | Exit | TELADOC HEALTH INC | $0 | – | -110,000 | -100.0% | -0.04% | – |
| KRTX | Exit | KARUNA THERAPEUTICS INC | $0 | – | -14,000 | -100.0% | -0.05% | – |
| Exit | VIGIL NEUROSCIENCE INC | $0 | – | -448,891 | -100.0% | -0.05% | – | |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -842,366 | -100.0% | -0.06% | – |
| APLS | Exit | APELLIS PHARMACEUTICALS INCcall | $0 | – | -77,500 | -100.0% | -0.06% | – |
| NXTC | Exit | NEXTCURE INC | $0 | – | -2,711,013 | -100.0% | -0.07% | – |
| Exit | YS BIOPHARMA CO LTDordinary shares | $0 | – | -4,541,422 | -100.0% | -0.08% | – | |
| CUTR | Exit | CUTERA INC | $0 | – | -603,100 | -100.0% | -0.08% | – |
| RLAY | Exit | RELAY THERAPEUTICS INC | $0 | – | -501,966 | -100.0% | -0.09% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INCcall | $0 | – | -100,000 | -100.0% | -0.09% | – |
| DXCM | Exit | DEXCOM INCcall | $0 | – | -50,000 | -100.0% | -0.10% | – |
| MORF | Exit | MORPHIC HLDG INC | $0 | – | -208,500 | -100.0% | -0.10% | – |
| CGEM | Exit | CULLINAN ONCOLOGY INC | $0 | – | -544,848 | -100.0% | -0.10% | – |
| Exit | KENVUE INCcall | $0 | – | -250,000 | -100.0% | -0.11% | – | |
| ORIC | Exit | ORIC PHARMACEUTICALS INC | $0 | – | -893,668 | -100.0% | -0.12% | – |
| NSPR | Exit | INSPIREMD INC | $0 | – | -1,860,405 | -100.0% | -0.13% | – |
| Exit | KENVUE INC | $0 | – | -312,404 | -100.0% | -0.13% | – | |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -5,463,000 | -100.0% | -0.14% | – |
| PASG | Exit | PASSAGE BIO INC | $0 | – | -10,124,576 | -100.0% | -0.14% | – |
| Exit | MOONLAKE IMMUNOTHERAPEUTICSclass a ord | $0 | – | -117,000 | -100.0% | -0.14% | – | |
| GILD | Exit | GILEAD SCIENCES INC | $0 | – | -100,000 | -100.0% | -0.16% | – |
| XFOR | Exit | X4 PHARMACEUTICALS INC | $0 | – | -7,133,515 | -100.0% | -0.16% | – |
| FUSN | Exit | FUSION PHARMACEUTICALS INC | $0 | – | -3,122,770 | -100.0% | -0.17% | – |
| Exit | INVIVYD INC | $0 | – | -5,270,400 | -100.0% | -0.19% | – | |
| GDRX | Exit | GOODRX HLDGS INC | $0 | – | -1,595,000 | -100.0% | -0.19% | – |
| SGEN | Exit | SEAGEN INC | $0 | – | -42,600 | -100.0% | -0.19% | – |
| CRVS | Exit | CORVUS PHARMACEUTICALS INC | $0 | – | -6,943,654 | -100.0% | -0.22% | – |
| ARQT | Exit | ARCUTIS BIOTHERAPEUTICS INC | $0 | – | -1,914,479 | -100.0% | -0.22% | – |
| AVTE | Exit | AEROVATE THERAPEUTICS INC | $0 | – | -756,930 | -100.0% | -0.22% | – |
| SGEN | Exit | SEAGEN INCcall | $0 | – | -50,000 | -100.0% | -0.22% | – |
| REGN | Exit | REGENERON PHARMACEUTICALS | $0 | – | -13,500 | -100.0% | -0.24% | – |
| KNTE | Exit | KINNATE BIOPHARMA INC | $0 | – | -8,009,729 | -100.0% | -0.24% | – |
| ACET | Exit | ADICET BIO INC | $0 | – | -8,322,140 | -100.0% | -0.24% | – |
| ARWR | Exit | ARROWHEAD PHARMACEUTICALS IN | $0 | – | -433,651 | -100.0% | -0.25% | – |
| Exit | VENTYX BIOSCIENCES INC | $0 | – | -340,384 | -100.0% | -0.25% | – | |
| IMTX | Exit | IMMATICS N.V | $0 | – | -1,050,200 | -100.0% | -0.26% | – |
| Exit | TURNSTONE BIOLOGICS CORP | $0 | – | -3,099,265 | -100.0% | -0.26% | – | |
| Exit | VERASTEM INC | $0 | – | -1,529,115 | -100.0% | -0.26% | – | |
| RYTM | Exit | RHYTHM PHARMACEUTICALS INC | $0 | – | -583,642 | -100.0% | -0.28% | – |
| IKNA | Exit | IKENA ONCOLOGY INC | $0 | – | -3,186,166 | -100.0% | -0.29% | – |
| ALXO | Exit | ALX ONCOLOGY HLDGS INC | $0 | – | -2,871,000 | -100.0% | -0.29% | – |
| QURE | Exit | UNIQURE NV | $0 | – | -2,064,455 | -100.0% | -0.29% | – |
| SRRK | Exit | SCHOLAR ROCK HLDG CORP | $0 | – | -2,033,789 | -100.0% | -0.31% | – |
| ARGX | Exit | ARGENX SEsponsored adr | $0 | – | -32,600 | -100.0% | -0.34% | – |
| AZN | Exit | ASTRAZENECA PLCcall | $0 | – | -250,000 | -100.0% | -0.36% | – |
| AKRO | Exit | AKERO THERAPEUTICS INC | $0 | – | -350,000 | -100.0% | -0.38% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -1,284,000 | -100.0% | -0.40% | – |
| ABCL | Exit | ABCELLERA BIOLOGICS INC | $0 | – | -4,180,768 | -100.0% | -0.41% | – |
| RAPT | Exit | RAPT THERAPEUTICS INC | $0 | – | -1,244,945 | -100.0% | -0.44% | – |
| VERA | Exit | VERA THERAPEUTICS INCcl a | $0 | – | -1,518,115 | -100.0% | -0.44% | – |
| Exit | NEUMORA THERAPEUTICS INC. | $0 | – | -1,500,000 | -100.0% | -0.45% | – | |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -4,707,458 | -100.0% | -0.46% | – |
| TELA | Exit | TELA BIO INC | $0 | – | -2,835,542 | -100.0% | -0.48% | – |
| GRCL | Exit | GRACELL BIOTECHNOLOGIES INCsponsored ads | $0 | – | -9,308,726 | -100.0% | -0.57% | – |
| Exit | APOGEE THERAPEUTICS INC | $0 | – | -1,427,901 | -100.0% | -0.65% | – | |
| HZNP | Exit | HORIZON THERAPEUTICS PUB L | $0 | – | -266,400 | -100.0% | -0.66% | – |
| ICLR | Exit | ICON PLC | $0 | – | -132,200 | -100.0% | -0.69% | – |
| XENE | Exit | XENON PHARMACEUTICALS INC | $0 | – | -958,793 | -100.0% | -0.70% | – |
| JANX | Exit | JANUX THERAPEUTICS INC | $0 | – | -3,317,927 | -100.0% | -0.71% | – |
| PRLD | Exit | PRELUDE THERAPEUTICS INC | $0 | – | -10,909,256 | -100.0% | -0.72% | – |
| AMGN | Exit | AMGEN INC | $0 | – | -127,300 | -100.0% | -0.73% | – |
| SBTX | Exit | ARS PHARMACEUTICALS INC | $0 | – | -9,240,887 | -100.0% | -0.74% | – |
| UNH | Exit | UNITEDHEALTH GROUP INC | $0 | – | -70,000 | -100.0% | -0.75% | – |
| Exit | THIRD HARMONIC BIO INC | $0 | – | -5,779,071 | -100.0% | -0.78% | – | |
| MDGL | Exit | MADRIGAL PHARMACEUTICALS INC | $0 | – | -253,309 | -100.0% | -0.79% | – |
| TERN | Exit | TERNS PHARMACEUTICALS INC | $0 | – | -7,619,135 | -100.0% | -0.81% | – |
| NPCE | Exit | NEUROPACE INC | $0 | – | -4,012,281 | -100.0% | -0.83% | – |
| SCPH | Exit | SCPHARMACEUTICALS INC | $0 | – | -5,559,528 | -100.0% | -0.84% | – |
| RPTX | Exit | REPARE THERAPEUTICS INC | $0 | – | -3,322,488 | -100.0% | -0.85% | – |
| PMVP | Exit | PMV PHARMACEUTICALS INC | $0 | – | -6,563,077 | -100.0% | -0.86% | – |
| NTRA | Exit | NATERA INC | $0 | – | -920,581 | -100.0% | -0.86% | – |
| CMPX | Exit | COMPASS THERAPEUTICS INC | $0 | – | -22,362,850 | -100.0% | -0.94% | – |
| Exit | PRELUDE THERAPEUTICS INCnonvoting | $0 | – | -12,048,773 | -100.0% | -0.96% | – | |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -4,081,592 | -100.0% | -0.99% | – |
| NBIX | Exit | NEUROCRINE BIOSCIENCES INC | $0 | – | -415,900 | -100.0% | -0.99% | – |
| Exit | THESEUS PHARMACEUTICALS INC | $0 | – | -17,713,600 | -100.0% | -1.01% | – | |
| APLS | Exit | APELLIS PHARMACEUTICALS INC | $0 | – | -1,260,500 | -100.0% | -1.02% | – |
| KROS | Exit | KEROS THERAPEUTICS INC | $0 | – | -1,514,734 | -100.0% | -1.03% | – |
| SIBN | Exit | SI-BONE INC | $0 | – | -2,292,531 | -100.0% | -1.03% | – |
| ABBV | Exit | ABBVIE INC | $0 | – | -330,000 | -100.0% | -1.04% | – |
| PCVX | Exit | VAXCYTE INC | $0 | – | -1,007,148 | -100.0% | -1.09% | – |
| Exit | R1 RCM INC | $0 | – | -3,441,000 | -100.0% | -1.10% | – | |
| Exit | ACELYRIN INC | $0 | – | -5,326,302 | -100.0% | -1.15% | – | |
| VRTX | Exit | VERTEX PHARMACEUTICALS INC | $0 | – | -165,400 | -100.0% | -1.22% | – |
| Exit | RAYZEBIO INC | $0 | – | -2,622,909 | -100.0% | -1.24% | – | |
| VRNA | Exit | VERONA PHARMA PLCsponsored ads | $0 | – | -3,777,778 | -100.0% | -1.31% | – |
| SRPT | Exit | SAREPTA THERAPEUTICS INC | $0 | – | -529,200 | -100.0% | -1.36% | – |
| CI | Exit | THE CIGNA GROUP | $0 | – | -231,500 | -100.0% | -1.41% | – |
| Exit | APOLLOMICS INC | $0 | – | -17,993,635 | -100.0% | -1.43% | – | |
| TMO | Exit | THERMO FISHER SCIENTIFIC INC | $0 | – | -143,800 | -100.0% | -1.55% | – |
| SYK | Exit | STRYKER CORPORATION | $0 | – | -269,000 | -100.0% | -1.56% | – |
| EVH | Exit | EVOLENT HEALTH INCcl a | $0 | – | -2,895,632 | -100.0% | -1.68% | – |
| XTNT | Exit | XTANT MED HLDGS INC | $0 | – | -73,114,592 | -100.0% | -1.71% | – |
| THC | Exit | TENET HEALTHCARE CORP | $0 | – | -1,224,400 | -100.0% | -1.71% | – |
| EWTX | Exit | EDGEWISE THERAPEUTICS INC | $0 | – | -14,567,176 | -100.0% | -1.77% | – |
| BAX | Exit | BAXTER INTL INC | $0 | – | -2,239,900 | -100.0% | -1.80% | – |
| MRTX | Exit | MIRATI THERAPEUTICS INC | $0 | – | -1,959,050 | -100.0% | -1.81% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -2,896,074 | -100.0% | -1.83% | – |
| UTHR | Exit | UNITED THERAPEUTICS CORP DEL | $0 | – | -401,900 | -100.0% | -1.93% | – |
| SWTX | Exit | SPRINGWORKS THERAPEUTICS INC | $0 | – | -3,968,588 | -100.0% | -1.95% | – |
| IONS | Exit | IONIS PHARMACEUTICALS INC | $0 | – | -2,169,500 | -100.0% | -2.09% | – |
| LLY | Exit | ELI LILLY & CO | $0 | – | -186,000 | -100.0% | -2.12% | – |
| Exit | DISC MEDICINE INC | $0 | – | -2,269,637 | -100.0% | -2.26% | – | |
| MRK | Exit | MERCK & CO INC | $0 | – | -1,055,000 | -100.0% | -2.31% | – |
| Exit | ENLIVEN THERAPEUTICS INC | $0 | – | -8,998,338 | -100.0% | -2.61% | – | |
| BMRN | Exit | BIOMARIN PHARMACEUTICAL INC | $0 | – | -1,615,210 | -100.0% | -3.04% | – |
| BIIB | Exit | BIOGEN INC | $0 | – | -556,800 | -100.0% | -3.04% | – |
| ISRG | Exit | INTUITIVE SURGICAL INC | $0 | – | -499,000 | -100.0% | -3.10% | – |
| HUM | Exit | HUMANA INC | $0 | – | -342,500 | -100.0% | -3.54% | – |
| BSX | Exit | BOSTON SCIENTIFIC CORP | $0 | – | -3,306,800 | -100.0% | -3.71% | – |
| SVA | Exit | SINOVAC BIOTECH LTD | $0 | – | -2,718,735 | -100.0% | -7.22% | – |
About Orbimed Advisors
Orbimed Advisors is a leading healthcare-focused investment firm that manages over $16 billion in assets. The firm was founded in 1998 by Samuel Isaly, who has over 50 years of experience in the healthcare industry. Isaly is widely regarded as a pioneer in the field of healthcare investing and has been recognized for his contributions to the industry by numerous organizations.
Orbimed Advisors has a team of over 100 professionals, including investment professionals, research analysts, and operational experts. The firm has offices in New York, San Francisco, Shanghai, and Mumbai, and invests in companies across the healthcare spectrum, including biotechnology, pharmaceuticals, medical devices, and healthcare services.
The firm's investment philosophy is based on a deep understanding of the healthcare industry and a rigorous approach to due diligence. Orbimed Advisors seeks to identify companies with innovative technologies and strong management teams that have the potential to transform the healthcare landscape.
Orbimed Advisors has a strong track record of success, with numerous successful investments in companies such as Juno Therapeutics, Spark Therapeutics, and Kite Pharma. The firm's leadership team, which includes CEO Sven Borho, COO Jonathan Silverstein, and Chief Investment Officer Carl Gordon, has decades of experience in the healthcare industry and is widely respected for their expertise and insights.
Overall, Orbimed Advisors is a leading healthcare investment firm that has a proven track record of success and a deep understanding of the healthcare industry. Investors looking to gain exposure to the healthcare sector may want to consider Orbimed Advisors as a potential investment opportunity.
It's important to note that this information is for educational purposes only and has not been fact-checked. As with any investment, it's important to do your own research and consult with a financial advisor before making any investment decisions.
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| BIOGEN INC | 42 | Q3 2023 | 5.0% |
| VERTEX PHARMACEUTICALS INC | 42 | Q3 2023 | 3.7% |
| THERMO FISHER SCIENTIFIC INC | 42 | Q3 2023 | 3.2% |
| SINOVAC BIOTECH LTD | 41 | Q3 2023 | 7.2% |
| NEUROCRINE BIOSCIENCES INC | 41 | Q3 2023 | 2.7% |
| BOSTON SCIENTIFIC CORP | 40 | Q3 2023 | 5.6% |
| BRISTOL-MYERS SQUIBB CO | 40 | Q2 2023 | 5.2% |
| AMGEN INC | 40 | Q3 2023 | 5.5% |
| INTUITIVE SURGICAL INC | 40 | Q3 2023 | 3.8% |
| GILEAD SCIENCES INC | 39 | Q3 2023 | 5.5% |
View Orbimed Advisors's complete holdings history.
Latest significant ownerships (13-D/G)
| Filed | Shares | Percentage | |
|---|---|---|---|
| Ikena Oncology, Inc. | September 21, 2023 | 2,189,111 | 5.2% |
| Galecto, Inc. | September 18, 2023 | 749,557 | 2.8% |
| PMV Pharmaceuticals, Inc. | August 23, 2023 | 6,563,077 | 13.5% |
| Gracell Biotechnologies Inc. | August 11, 2023 | 7,641,531 | 8.0% |
| Xtant Medical Holdings, Inc. | August 03, 2023 | 73,114,592 | 56.7% |
| Turnstone Biologics Corp. | July 24, 2023 | 3,099,265 | 13.4% |
| Prelude Therapeutics Inc | May 24, 2023 | 15,716,642 | 28.6% |
| VectivBio Holding AG | May 24, 2023 | 5,156,561 | 7.7% |
| Fusion Pharmaceuticals Inc. | May 16, 2023 | 2,930,670 | 4.6% |
| Verona Pharma plc | May 16, 2023 | 3,777,778 | 4.8% |
View Orbimed Advisors's complete significant-ownership history.
Latest filings
| Type | Filed |
|---|---|
| 4 | 2024-05-08 |
| SC 13D/A | 2024-05-08 |
| 4 | 2024-05-03 |
| 4 | 2024-04-26 |
| 4 | 2024-04-23 |
| 4 | 2024-04-18 |
| 4 | 2024-04-15 |
| 3/A | 2024-04-12 |
| SC 13D/A | 2024-04-12 |
| 4 | 2024-04-05 |
View Orbimed Advisors's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.