$1.3 Billion is the total value of FRAZIER MANAGEMENT LLC's 43 reported holdings in Q4 2021. The portfolio turnover from Q3 2021 to Q4 2021 was 24.4% .
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | $174,926,000 | -13.2% | 8,434,232 | 0.0% | 13.47% | -16.5% | |
| PHAT | PHATHOM PHARMACEUTICALS INC | $114,625,000 | -38.7% | 5,827,415 | 0.0% | 8.82% | -41.0% | |
| IMAGO BIOSCIENCES INC | $70,449,000 | +18.4% | 2,971,274 | 0.0% | 5.42% | +13.9% | ||
| SNDX | Buy | SYNDAX PHARMACEUTICALS INC | $60,680,000 | +167.3% | 2,772,062 | +133.3% | 4.67% | +157.1% |
| GRTS | GRITSTONE BIO INC | $60,021,000 | +19.1% | 4,667,242 | 0.0% | 4.62% | +14.6% | |
| MIRM | MIRUM PHARMACEUTICALS INC | $56,892,000 | -19.9% | 3,566,912 | 0.0% | 4.38% | -23.0% | |
| PCVX | VAXCYTE INC | $54,944,000 | -6.2% | 2,309,554 | 0.0% | 4.23% | -9.8% | |
| KRYS | KRYSTAL BIOTECH INC | $53,949,000 | +34.0% | 771,250 | 0.0% | 4.15% | +28.9% | |
| New | PARDES BIOSCIENCES INC | $40,229,000 | – | 2,457,507 | +100.0% | 3.10% | – | |
| CRNX | Buy | CRINETICS PHARMACEUTICALS IN | $39,328,000 | +119.5% | 1,384,293 | +62.6% | 3.03% | +111.2% |
| KDNY | Buy | CHINOOK THERAPEUTICS INC | $38,686,000 | +81.3% | 2,371,918 | +41.9% | 2.98% | +74.5% |
| BCYC | Buy | BICYCLE THERAPEUTICS PLCsponsored ads | $33,797,000 | +83.5% | 555,240 | +25.4% | 2.60% | +76.5% |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $33,362,000 | -49.4% | 1,747,622 | -34.7% | 2.57% | -51.3% |
| TARS | TARSUS PHARMACEUTICALS INC | $31,886,000 | +4.4% | 1,417,157 | 0.0% | 2.46% | +0.5% | |
| PASG | PASSAGE BIO INC | $31,809,000 | -36.2% | 5,009,219 | 0.0% | 2.45% | -38.7% | |
| ANAB | ANAPTYSBIO INC | $31,265,000 | +28.1% | 899,700 | 0.0% | 2.41% | +23.3% | |
| ISEE | IVERIC BIO INC | $30,738,000 | +3.0% | 1,838,402 | 0.0% | 2.37% | -1.0% | |
| VRDN | VIRIDIAN THERAPEUTICS INC | $29,758,000 | +20.2% | 1,505,200 | 0.0% | 2.29% | +15.6% | |
| SRRA | Buy | SIERRA ONCOLOGY INC | $27,498,000 | +55.9% | 1,264,861 | +57.2% | 2.12% | +50.0% |
| STRO | Buy | SUTRO BIOPHARMA INC | $26,434,000 | -4.7% | 1,776,479 | +21.0% | 2.04% | -8.3% |
| ALPN | Buy | ALPINE IMMUNE SCIENCES INC | $24,721,000 | +30.8% | 1,784,913 | +0.7% | 1.90% | +25.8% |
| SLN | New | SILENCE THERAPEUTICS PLCads | $21,171,000 | – | 886,173 | +100.0% | 1.63% | – |
| AUTL | Buy | AUTOLUS THERAPEUTICS PLCspon ads | $19,446,000 | -15.9% | 3,746,857 | +6.1% | 1.50% | -19.1% |
| MRUS | New | MERUS N V | $17,782,000 | – | 559,179 | +100.0% | 1.37% | – |
| REPL | Buy | REPLIMUNE GROUP INC | $17,638,000 | +20.9% | 650,862 | +32.3% | 1.36% | +16.4% |
| TYRA BIOSCIENCES INC | $17,588,000 | -20.0% | 1,250,000 | 0.0% | 1.35% | -23.0% | ||
| KALV | Buy | KALVISTA PHARMACEUTICALS INC | $17,266,000 | +531.1% | 1,305,087 | +732.3% | 1.33% | +506.8% |
| TCDA | New | TRICIDA INC | $17,054,000 | – | 1,783,893 | +100.0% | 1.31% | – |
| COGT | New | COGENT BIOSCIENCES INC | $15,229,000 | – | 1,774,891 | +100.0% | 1.17% | – |
| FLACU | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $14,890,000 | -1.1% | 1,501,000 | 0.0% | 1.15% | -4.9% | |
| ARVN | New | ARVINAS INC | $13,451,000 | – | 163,763 | +100.0% | 1.04% | – |
| GRCL | Buy | GRACELL BIOTECHNOLOGIES INCsponsored ads | $9,996,000 | -15.4% | 1,654,938 | +94.3% | 0.77% | -18.5% |
| RGNX | REGENXBIO INC | $7,711,000 | -22.0% | 235,809 | 0.0% | 0.59% | -24.9% | |
| EPIX | Buy | ESSA PHARMA INC | $7,717,000 | +169.2% | 543,470 | +51.7% | 0.59% | +159.4% |
| AVDL | AVADEL PHARMACEUTICALS PLCsponsored adr | $7,691,000 | -17.5% | 951,814 | 0.0% | 0.59% | -20.6% | |
| ACRS | ACLARIS THERAPEUTICS INC | $5,937,000 | -19.2% | 408,329 | 0.0% | 0.46% | -22.3% | |
| MTEM | MOLECULAR TEMPLATES INC | $5,386,000 | -41.6% | 1,374,047 | 0.0% | 0.42% | -43.8% | |
| APTX | APTINYX INC | $5,028,000 | +14.1% | 1,883,244 | 0.0% | 0.39% | +9.6% | |
| IMVT | IMMUNOVANT INC | $4,991,000 | -1.9% | 585,759 | 0.0% | 0.38% | -5.7% | |
| SRRK | SCHOLAR ROCK HLDG CORP | $3,875,000 | -24.8% | 156,000 | 0.0% | 0.30% | -27.7% | |
| EPZM | EPIZYME INC | $1,848,000 | -51.2% | 739,369 | 0.0% | 0.14% | -53.1% | |
| ALNA | Sell | ALLENA PHARMACEUTICALS | $978,000 | -67.5% | 1,651,357 | -50.4% | 0.08% | -68.8% |
| NABRIVA THERAPEUTICS PLC | $255,000 | -49.7% | 425,650 | 0.0% | 0.02% | -51.2% | ||
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -550,000 | -100.0% | -0.15% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -241,000 | -100.0% | -0.16% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -433,247 | -100.0% | -0.21% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -3,123,107 | -100.0% | -4.40% | – |
Original filings
The following EDGAR filing(s) were analyzed to create this report:
- View 13F-HR filed 2022-02-08
Signatures
The EDGAR filing(s) were signed by:
Top long-term holdings
| Name | Quarters owned | Latest quarter owned | Max weighting |
|---|---|---|---|
| COLLEGIUM PHARMACEUTICAL INC | 21 | Q4 2020 | 37.0% |
| ANAPTYSBIO INC | 20 | Q4 2021 | 63.7% |
| CIDARA THERAPEUTICS INC | 20 | Q3 2020 | 17.2% |
| IOVANCE BIOTHERAPEUTICS INC | 19 | Q4 2021 | 13.7% |
| ALLENA PHARMACEUTICALS INC | 18 | Q1 2022 | 11.9% |
| ALPINE IMMUNE SCIENCES INC | 18 | Q4 2021 | 9.1% |
| APTINYX INC | 15 | Q4 2021 | 16.9% |
| KRYSTAL BIOTECH INC | 14 | Q4 2021 | 9.7% |
| GRITSTONE ONCOLOGY INC | 14 | Q4 2021 | 8.2% |
| SIERRA ONCOLOGY INC | 12 | Q4 2019 | 6.6% |
View FRAZIER MANAGEMENT LLC's complete holdings history.
Latest filings
| Type | Filed |
|---|---|
| 13F-HR | 2022-11-14 |
| 13F-HR | 2022-08-10 |
| 13F-HR | 2022-05-13 |
| 13F-HR | 2022-02-08 |
| 13F-HR | 2021-11-12 |
| 13F-HR | 2021-08-11 |
| 13F-HR | 2021-05-12 |
| 13F-HR | 2021-02-11 |
| 13F-HR | 2020-11-12 |
| 13F-HR | 2020-08-04 |
View FRAZIER MANAGEMENT LLC's complete filings history.
All filings
- Holdings (13F-HR)
- Significant ownership (13-D/G)
- Insider transactions (4, 5, 6)
- Events (8-K)
- Shareholder votes (proxy)
View complete filings history.