Q3 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| New | No remaining holdings | $0 | – | 0 | – | 0.00% | – | |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -20,316 | – | -100.00% | – |
Q2 2022
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SRRA | New | SIERRA ONCOLOGY INC | $1,117,000 | – | 20,316 | – | 100.00% | – |
Q4 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -425,650 | – | -0.04% | – | |
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -550,000 | – | -0.15% | – |
| GRTX | Exit | GALERA THERAPEUTICS INC | $0 | – | -241,000 | – | -0.16% | – |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -433,247 | – | -0.21% | – |
| KALV | Exit | KALVISTA PHARMACEUTICALS INC | $0 | – | -156,807 | – | -0.22% | – |
| EPIX | Exit | ESSA PHARMA INC | $0 | – | -358,346 | – | -0.23% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS | $0 | – | -3,330,373 | – | -0.24% | – |
| EPZM | Exit | EPIZYME INC | $0 | – | -739,369 | – | -0.30% | – |
| APTX | Exit | APTINYX INC | $0 | – | -1,883,244 | – | -0.35% | – |
| IMVT | Exit | IMMUNOVANT INC | $0 | – | -585,759 | – | -0.41% | – |
| SRRK | Exit | SCHOLAR ROCK HLDG CORP | $0 | – | -156,000 | – | -0.41% | – |
| ACRS | Exit | ACLARIS THERAPEUTICS INC | $0 | – | -408,329 | – | -0.59% | – |
| MTEM | Exit | MOLECULAR TEMPLATES INC | $0 | – | -1,374,047 | – | -0.74% | – |
| AVDL | Exit | AVADEL PHARMACEUTICALS PLCsponsored adr | $0 | – | -951,814 | – | -0.75% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -235,809 | – | -0.79% | – |
| GRCL | Exit | GRACELL BIOTECHNOLOGIES INCsponsored ads | $0 | – | -851,638 | – | -0.94% | – |
| REPL | Exit | REPLIMUNE GROUP INC | $0 | – | -491,998 | – | -1.17% | – |
| FLACU | Exit | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $0 | – | -1,501,000 | – | -1.20% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -804,667 | – | -1.41% | – |
| CRNX | Exit | CRINETICS PHARMACEUTICALS IN | $0 | – | -851,306 | – | -1.43% | – |
| BCYC | Exit | BICYCLE THERAPEUTICS PLCsponsored ads | $0 | – | -442,880 | – | -1.47% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -1,771,844 | – | -1.51% | – |
| KDNY | Exit | CHINOOK THERAPEUTICS INC | $0 | – | -1,671,918 | – | -1.71% | – |
| Exit | TYRA BIOSCIENCES INC | $0 | – | -1,250,000 | – | -1.76% | – | |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -1,188,135 | – | -1.82% | – |
| AUTL | Exit | AUTOLUS THERAPEUTICS PLCspon ads | $0 | – | -3,530,657 | – | -1.85% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -899,700 | – | -1.95% | – |
| VRDN | Exit | VIRIDIAN THERAPEUTICS INC | $0 | – | -1,505,200 | – | -1.98% | – |
| STRO | Exit | SUTRO BIOPHARMA INC | $0 | – | -1,468,663 | – | -2.22% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -1,838,402 | – | -2.39% | – |
| TARS | Exit | TARSUS PHARMACEUTICALS INC | $0 | – | -1,417,157 | – | -2.44% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -771,250 | – | -3.22% | – |
| PASG | Exit | PASSAGE BIO INC | $0 | – | -5,009,219 | – | -3.99% | – |
| GRTS | Exit | GRITSTONE BIO INC | $0 | – | -4,667,242 | – | -4.03% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -3,123,107 | – | -4.40% | – | |
| PCVX | Exit | VAXCYTE INC | $0 | – | -2,309,554 | – | -4.69% | – |
| Exit | IMAGO BIOSCIENCES INC | $0 | – | -2,971,274 | – | -4.76% | – | |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -2,674,299 | – | -5.28% | – |
| MIRM | Exit | MIRUM PHARMACEUTICALS INC | $0 | – | -3,566,912 | – | -5.68% | – |
| PHAT | Exit | PHATHOM PHARMACEUTICALS INC | $0 | – | -5,827,415 | – | -14.97% | – |
| ARQT | Exit | ARCUTIS BIOTHERAPEUTICS INC | $0 | – | -8,434,232 | – | -16.12% | – |
Q3 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| IOVA | Buy | IOVANCE BIOTHERAPEUTICS INC | $65,948,000 | +18.5% | 2,674,299 | +25.1% | 5.28% | +2.9% |
| New | IMAGO BIOSCIENCES INC | $59,515,000 | – | 2,971,274 | – | 4.76% | – | |
| GRTS | Buy | GRITSTONE BIO INC | $50,406,000 | +435.6% | 4,667,242 | +352.7% | 4.03% | +364.6% |
| KRYS | Sell | KRYSTAL BIOTECH INC | $40,267,000 | -24.8% | 771,250 | -2.1% | 3.22% | -34.8% |
| ISEE | Sell | IVERIC BIO INC | $29,856,000 | +85.9% | 1,838,402 | -27.7% | 2.39% | +61.3% |
| STRO | Buy | SUTRO BIOPHARMA INC | $27,743,000 | +49.0% | 1,468,663 | +46.7% | 2.22% | +29.3% |
| VRDN | New | VIRIDIAN THERAPEUTICS INC | $24,761,000 | – | 1,505,200 | – | 1.98% | – |
| AUTL | Buy | AUTOLUS THERAPEUTICS PLCspon ads | $23,126,000 | +52.5% | 3,530,657 | +54.6% | 1.85% | +32.2% |
| New | TYRA BIOSCIENCES INC | $21,988,000 | – | 1,250,000 | – | 1.76% | – | |
| KDNY | Buy | CHINOOK THERAPEUTICS INC | $21,334,000 | +37.4% | 1,671,918 | +52.0% | 1.71% | +19.2% |
| ALPN | Sell | ALPINE IMMUNE SCIENCES INC | $18,906,000 | -18.3% | 1,771,844 | -31.1% | 1.51% | -29.1% |
| BCYC | New | BICYCLE THERAPEUTICS PLCsponsored ads | $18,419,000 | – | 442,880 | – | 1.47% | – |
| CRNX | New | CRINETICS PHARMACEUTICALS IN | $17,920,000 | – | 851,306 | – | 1.43% | – |
| SRRA | Buy | SIERRA ONCOLOGY INC | $17,638,000 | +346.6% | 804,667 | +296.8% | 1.41% | +287.6% |
| REPL | New | REPLIMUNE GROUP INC | $14,583,000 | – | 491,998 | – | 1.17% | – |
| GRCL | New | GRACELL BIOTECHNOLOGIES INCsponsored ads | $11,812,000 | – | 851,638 | – | 0.94% | – |
| RGNX | Sell | REGENXBIO INC | $9,885,000 | -27.7% | 235,809 | -33.0% | 0.79% | -37.3% |
| AVDL | Buy | AVADEL PHARMACEUTICALS PLCsponsored adr | $9,328,000 | +139.7% | 951,814 | +64.6% | 0.75% | +107.8% |
| ACRS | Buy | ACLARIS THERAPEUTICS INC | $7,350,000 | +12.9% | 408,329 | +10.1% | 0.59% | -2.0% |
| IMVT | Buy | IMMUNOVANT INC | $5,090,000 | +89.6% | 585,759 | +130.6% | 0.41% | +64.1% |
| EPIX | Buy | ESSA PHARMA INC | $2,867,000 | -68.3% | 358,346 | +13.2% | 0.23% | -72.5% |
| KALV | New | KALVISTA PHARMACEUTICALS INC | $2,736,000 | – | 156,807 | – | 0.22% | – |
| BLU | Sell | BELLUS HEALTH INC NEW | $2,649,000 | -34.3% | 433,247 | -66.6% | 0.21% | -43.0% |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -2,082,789 | – | -5.29% | – |
Q2 2021
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INC | $230,170,000 | – | 8,434,232 | – | 21.23% | – |
| PHAT | New | PHATHOM PHARMACEUTICALS INC | $197,258,000 | – | 5,827,415 | – | 18.19% | – |
| PASG | New | PASSAGE BIO INC | $66,322,000 | – | 5,009,219 | – | 6.12% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $61,672,000 | – | 3,566,912 | – | 5.69% | – |
| TBIO | New | TRANSLATE BIO INC | $57,360,000 | – | 2,082,789 | – | 5.29% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $55,631,000 | – | 2,137,999 | – | 5.13% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $53,576,000 | – | 787,876 | – | 4.94% | – |
| PCVX | New | VAXCYTE INC | $51,988,000 | – | 2,309,554 | – | 4.79% | – |
| TARS | New | TARSUS PHARMACEUTICALS INC | $41,069,000 | – | 1,417,157 | – | 3.79% | – |
| New | TRILLIUM THERAPEUTICS INC | $30,275,000 | – | 3,123,107 | – | 2.79% | – | |
| ANAB | New | ANAPTYSBIO INC | $23,329,000 | – | 899,700 | – | 2.15% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $23,143,000 | – | 2,571,450 | – | 2.13% | – |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $20,400,000 | – | 1,188,135 | – | 1.88% | – |
| STRO | New | SUTRO BIOPHARMA INC | $18,616,000 | – | 1,001,421 | – | 1.72% | – |
| ISEE | New | IVERIC BIO INC | $16,056,000 | – | 2,544,500 | – | 1.48% | – |
| KDNY | New | CHINOOK THERAPEUTICS INC | $15,532,000 | – | 1,100,000 | – | 1.43% | – |
| AUTL | New | AUTOLUS THERAPEUTICS PLCspon ads | $15,166,000 | – | 2,283,966 | – | 1.40% | – |
| FLACU | New | FRAZIER LIFESCIENCES ACQU COunit 12/09/2025 | $15,085,000 | – | 1,501,000 | – | 1.39% | – |
| RGNX | New | REGENXBIO INC | $13,673,000 | – | 351,954 | – | 1.26% | – |
| MTEM | New | MOLECULAR TEMPLATES INC | $10,745,000 | – | 1,374,047 | – | 0.99% | – |
| GRTS | New | GRITSTONE BIO INC | $9,412,000 | – | 1,030,878 | – | 0.87% | – |
| EPIX | New | ESSA PHARMA INC | $9,046,000 | – | 316,616 | – | 0.83% | – |
| ACRS | New | ACLARIS THERAPEUTICS INC | $6,510,000 | – | 370,733 | – | 0.60% | – |
| EPZM | New | EPIZYME INC | $6,144,000 | – | 739,369 | – | 0.57% | – |
| APTX | New | APTINYX INC | $5,330,000 | – | 1,883,244 | – | 0.49% | – |
| SRRK | New | SCHOLAR ROCK HLDG CORP | $4,508,000 | – | 156,000 | – | 0.42% | – |
| FRLN | New | FREELINE THERAPEUTICS HLDGSsponsored ads | $4,483,000 | – | 550,000 | – | 0.41% | – |
| ALNA | New | ALLENA PHARMACEUTICALS | $4,329,000 | – | 3,330,373 | – | 0.40% | – |
| BLU | New | BELLUS HEALTH INC NEW | $4,030,000 | – | 1,296,743 | – | 0.37% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $3,949,000 | – | 202,803 | – | 0.36% | – |
| AVDL | New | AVADEL PHARMACEUTICALS PLCsponsored adr | $3,891,000 | – | 578,104 | – | 0.36% | – |
| IMVT | New | IMMUNOVANT INC | $2,685,000 | – | 254,000 | – | 0.25% | – |
| GRTX | New | GALERA THERAPEUTICS INC | $2,369,000 | – | 241,000 | – | 0.22% | – |
| New | NABRIVA THERAPEUTICS PLC | $575,000 | – | 425,650 | – | 0.05% | – |
Q4 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ETTX | Exit | ENTASIS THERAPEUTICS HLDGS I | $0 | – | -199,953 | – | -0.04% | – |
| Exit | BELLICUM PHARMACEUTICALS INC | $0 | – | -105,144 | – | -0.06% | – | |
| ITRM | Exit | ITERUM THERAPEUTICS PLC | $0 | – | -1,538,316 | – | -0.14% | – |
| NERV | Exit | MINERVA NEUROSCIENCES INC | $0 | – | -550,000 | – | -0.16% | – |
| VTVT | Exit | VTV THERAPEUTICS INCcl a | $0 | – | -1,062,000 | – | -0.17% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -202,803 | – | -0.19% | – |
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -4,256,526 | – | -0.20% | – | |
| BLU | Exit | BELLUS HEALTH INC NEW | $0 | – | -1,296,743 | – | -0.27% | – |
| CRDF | Exit | CARDIFF ONCOLOGY INC | $0 | – | -260,000 | – | -0.33% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,312,258 | – | -0.34% | – |
| RGNX | Exit | REGENXBIO INC | $0 | – | -174,200 | – | -0.43% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS INC | $0 | – | -3,330,373 | – | -0.44% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -2,061,758 | – | -0.49% | – |
| FRLN | Exit | FREELINE THERAPEUTICS HLDGSsponsored ads | $0 | – | -550,000 | – | -0.77% | – |
| APTX | Exit | APTINYX INC | $0 | – | -3,190,079 | – | -0.97% | – |
| RCKT | Exit | ROCKET PHARMACEUTICALS INC | $0 | – | -528,000 | – | -1.08% | – |
| ISEE | Exit | IVERIC BIO INC | $0 | – | -2,364,500 | – | -1.20% | – |
| ADVM | Exit | ADVERUM BIOTECHNOLOGIES INC | $0 | – | -1,437,028 | – | -1.33% | – |
| SNDX | Exit | SYNDAX PHARMACEUTICALS INC | $0 | – | -1,320,045 | – | -1.75% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -943,666 | – | -1.76% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -2,571,450 | – | -2.03% | – |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -2,182,789 | – | -2.67% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -2,316,447 | – | -3.07% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -895,000 | – | -3.46% | – |
| Exit | TRILLIUM THERAPEUTICS INC | $0 | – | -2,788,443 | – | -3.55% | – | |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -1,312,999 | – | -3.88% | – |
| PASG | Exit | PASSAGE BIO INC | $0 | – | -5,009,219 | – | -5.90% | – |
| MIRM | Exit | MIRUM PHARMACEUTICALS INC | $0 | – | -3,566,912 | – | -6.17% | – |
| PCVX | Exit | VAXCYTE INC | $0 | – | -2,309,554 | – | -10.24% | – |
| PHAT | Exit | PHATHOM PHARMACEUTICALS INC | $0 | – | -5,827,415 | – | -19.18% | – |
| ARQT | Exit | ARCUTIS BIOTHERAPEUTICS INC | $0 | – | -10,542,790 | – | -27.73% | – |
Q3 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| Buy | TRILLIUM THERAPEUTICS INC | $39,555,000 | +77.5% | 2,788,443 | +1.2% | 3.55% | +81.5% | |
| FRLN | New | FREELINE THERAPEUTICS HLDGSsponsored ads | $8,586,000 | – | 550,000 | – | 0.77% | – |
| RGNX | New | REGENXBIO INC | $4,794,000 | – | 174,200 | – | 0.43% | – |
| CRDF | New | CARDIFF ONCOLOGY INC | $3,689,000 | – | 260,000 | – | 0.33% | – |
| BLU | New | BELLUS HEALTH INC NEW | $2,959,000 | – | 1,296,743 | – | 0.27% | – |
| NERV | New | MINERVA NEUROSCIENCES INC | $1,749,000 | – | 550,000 | – | 0.16% | – |
| ETTX | Sell | ENTASIS THERAPEUTICS HLDGS I | $408,000 | -60.6% | 199,953 | -42.9% | 0.04% | -59.3% |
Q2 2020
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ARQT | New | ARCUTIS BIOTHERAPEUTICS INC | $318,814,000 | – | 10,542,790 | – | 28.00% | – |
| PHAT | New | PHATHOM PHARMACEUTICALS INC | $191,780,000 | – | 5,827,415 | – | 16.84% | – |
| PASG | New | PASSAGE BIO INC | $136,902,000 | – | 5,009,219 | – | 12.02% | – |
| PCVX | New | VAXCYTE INC | $73,005,000 | – | 2,309,554 | – | 6.41% | – |
| MIRM | New | MIRUM PHARMACEUTICALS INC | $69,412,000 | – | 3,566,912 | – | 6.10% | – |
| ANAB | New | ANAPTYSBIO INC | $51,749,000 | – | 2,316,447 | – | 4.54% | – |
| TBIO | New | TRANSLATE BIO INC | $39,116,000 | – | 2,182,789 | – | 3.44% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $37,071,000 | – | 895,000 | – | 3.26% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $36,042,000 | – | 1,312,999 | – | 3.16% | – |
| ADVM | New | ADVERUM BIOTECHNOLOGIES INC | $30,005,000 | – | 1,437,028 | – | 2.64% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $24,969,000 | – | 2,571,450 | – | 2.19% | – |
| New | TRILLIUM THERAPEUTICS INC | $22,288,000 | – | 2,755,000 | – | 1.96% | – | |
| SNDX | New | SYNDAX PHARMACEUTICALS INC | $19,563,000 | – | 1,320,045 | – | 1.72% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $16,514,000 | – | 943,666 | – | 1.45% | – |
| GRTS | New | GRITSTONE ONCOLOGY INC | $13,690,000 | – | 2,061,758 | – | 1.20% | – |
| APTX | New | APTINYX INC | $13,303,000 | – | 3,190,079 | – | 1.17% | – |
| ISEE | New | IVERIC BIO INC | $12,059,000 | – | 2,364,500 | – | 1.06% | – |
| RCKT | New | ROCKET PHARMACEUTICALS INC | $11,051,000 | – | 528,000 | – | 0.97% | – |
| ALNA | New | ALLENA PHARMACEUTICALS INC | $5,262,000 | – | 3,330,373 | – | 0.46% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $4,842,000 | – | 1,312,258 | – | 0.42% | – |
| New | NABRIVA THERAPEUTICS PLC | $2,871,000 | – | 4,256,526 | – | 0.25% | – | |
| SRRA | New | SIERRA ONCOLOGY INC | $2,454,000 | – | 202,803 | – | 0.22% | – |
| VTVT | New | VTV THERAPEUTICS INCcl a | $2,390,000 | – | 1,062,000 | – | 0.21% | – |
| ITRM | New | ITERUM THERAPEUTICS PLC | $1,831,000 | – | 1,538,316 | – | 0.16% | – |
| ETTX | New | ENTASIS THERAPEUTICS HLDGS I | $1,036,000 | – | 349,953 | – | 0.09% | – |
| New | BELLICUM PHARMACEUTICALS INC | $781,000 | – | 105,144 | – | 0.07% | – |
Q4 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| SYBX | Exit | SYNLOGIC INC | $0 | – | -282,649 | – | -0.20% | – |
| BLCM | Exit | BELLICUM PHARMACEUTICALS INC | $0 | – | -1,051,441 | – | -0.34% | – |
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -467,743 | – | -0.48% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,312,258 | – | -0.82% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -8,112,121 | – | -0.99% | – |
| ETTX | Exit | ENTASIS THERAPEUTICS HLDGS I | $0 | – | -1,349,953 | – | -2.52% | – |
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -4,256,526 | – | -2.66% | – | |
| ITRM | Exit | ITERUM THERAPEUTICS PLC | $0 | – | -1,538,316 | – | -2.78% | – |
| MLND | Exit | MILLENDO THERAPEUTICS INC | $0 | – | -1,396,615 | – | -3.10% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -2,571,450 | – | -3.18% | – |
| APTX | Exit | APTINYX INC | $0 | – | -3,190,079 | – | -3.48% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS INC | $0 | – | -3,330,373 | – | -4.10% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -2,061,758 | – | -5.57% | – |
| TBIO | Exit | TRANSLATE BIO INC | $0 | – | -2,182,789 | – | -6.76% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -1,887,332 | – | -6.77% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -895,000 | – | -9.72% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -1,750,665 | – | -9.96% | – |
| MIRM | Exit | MIRUM PHARMACEUTICALS INC | $0 | – | -3,566,912 | – | -11.22% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -2,316,447 | – | -25.34% | – |
Q3 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| MIRM | New | MIRUM PHARMACEUTICALS INC | $35,883,000 | – | 3,566,912 | – | 11.22% | – |
| IOVA | Sell | IOVANCE BIOTHERAPEUTICS INC | $31,862,000 | -40.6% | 1,750,665 | -20.0% | 9.96% | -27.5% |
| TBIO | Buy | TRANSLATE BIO INC | $21,631,000 | +1.8% | 2,182,789 | +29.7% | 6.76% | +24.2% |
| SYBX | Sell | SYNLOGIC INC | $647,000 | -91.8% | 282,649 | -67.3% | 0.20% | -90.0% |
Q2 2019
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ANAB | New | ANAPTYSBIO INC | $130,694,000 | – | 2,316,447 | – | 33.49% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $53,658,000 | – | 2,188,331 | – | 13.75% | – |
| KRYS | New | KRYSTAL BIOTECH INC | $36,042,000 | – | 895,000 | – | 9.24% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $24,818,000 | – | 1,887,332 | – | 6.36% | – |
| GRTS | New | GRITSTONE ONCOLOGY INC | $22,968,000 | – | 2,061,758 | – | 5.88% | – |
| TBIO | New | TRANSLATE BIO INC | $21,254,000 | – | 1,682,789 | – | 5.45% | – |
| MLND | New | MILLENDO THERAPEUTICS INC | $16,145,000 | – | 1,396,615 | – | 4.14% | – |
| ALNA | New | ALLENA PHARMACEUTICALS INC | $13,555,000 | – | 3,330,373 | – | 3.47% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $10,826,000 | – | 2,571,450 | – | 2.77% | – |
| APTX | New | APTINYX INC | $10,655,000 | – | 3,190,079 | – | 2.73% | – |
| ITRM | New | ITERUM THERAPEUTICS PLC | $10,584,000 | – | 1,538,316 | – | 2.71% | – |
| New | NABRIVA THERAPEUTICS PLC | $10,343,000 | – | 4,256,526 | – | 2.65% | – | |
| ETTX | New | ENTASIS THERAPEUTICS HLDGS I | $8,707,000 | – | 1,349,953 | – | 2.23% | – |
| SYBX | New | SYNLOGIC INC | $7,875,000 | – | 865,407 | – | 2.02% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $4,543,000 | – | 8,112,121 | – | 1.16% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $3,606,000 | – | 467,743 | – | 0.92% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $2,205,000 | – | 1,312,258 | – | 0.56% | – |
| BLCM | New | BELLICUM PHARMACEUTICALS INC | $1,787,000 | – | 1,051,441 | – | 0.46% | – |
Q4 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| KZR | Exit | KEZAR LIFE SCIENCES INC | $0 | – | -250,000 | – | -0.98% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,312,258 | – | -1.06% | – |
| BLCM | Exit | BELLICUM PHARMACEUTICALS INC | $0 | – | -1,051,441 | – | -1.19% | – |
| ITRM | Exit | ITERUM THERAPEUTICS PLC | $0 | – | -1,538,316 | – | -1.89% | – |
| KRYS | Exit | KRYSTAL BIOTECH INC | $0 | – | -625,000 | – | -2.01% | – |
| Exit | NABRIVA THERAPEUTICS PLC | $0 | – | -4,256,526 | – | -2.10% | – | |
| SYBX | Exit | SYNLOGIC INC | $0 | – | -865,407 | – | -2.25% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -8,112,121 | – | -2.52% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -2,199,011 | – | -2.55% | – |
| ETTX | Exit | ENTASIS THERAPEUTICS HLDGS I | $0 | – | -1,349,953 | – | -2.69% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -2,188,331 | – | -4.51% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -1,887,332 | – | -5.09% | – |
| GRTS | Exit | GRITSTONE ONCOLOGY INC | $0 | – | -2,061,762 | – | -5.38% | – |
| ALNA | Exit | ALLENA PHARMACEUTICALS INC | $0 | – | -3,330,373 | – | -6.55% | – |
| APTX | Exit | APTINYX INC | $0 | – | -3,190,079 | – | -16.92% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -2,316,447 | – | -42.32% | – |
Q3 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| GRTS | New | GRITSTONE ONCOLOGY INC | $29,359,000 | – | 2,061,762 | – | 5.38% | – |
| ETTX | New | ENTASIS THERAPEUTICS HLDGS I | $14,687,000 | – | 1,349,953 | – | 2.69% | – |
| SYBX | Buy | SYNLOGIC INC | $12,297,000 | +52.3% | 865,407 | +5.3% | 2.25% | +34.6% |
| New | NABRIVA THERAPEUTICS PLC | $11,493,000 | – | 4,256,526 | – | 2.10% | – | |
| KRYS | New | KRYSTAL BIOTECH INC | $10,988,000 | – | 625,000 | – | 2.01% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -2,600,014 | – | -8.41% | – |
Q2 2018
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ANAB | New | ANAPTYSBIO INC | $164,560,000 | – | 2,316,447 | – | 34.09% | – |
| APTX | New | APTINYX INC | $77,104,000 | – | 3,190,079 | – | 15.97% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $45,013,000 | – | 1,887,332 | – | 9.32% | – |
| ALNA | New | ALLENA PHARMACEUTICALS INC | $43,395,000 | – | 3,330,373 | – | 8.99% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $40,612,000 | – | 2,600,014 | – | 8.41% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $28,011,000 | – | 2,188,331 | – | 5.80% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $24,012,000 | – | 8,112,121 | – | 4.97% | – |
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $16,647,000 | – | 2,199,011 | – | 3.45% | – |
| ITRM | New | ITERUM THERAPEUTICS PLC | $16,414,000 | – | 1,538,316 | – | 3.40% | – |
| SYBX | New | SYNLOGIC INC | $8,075,000 | – | 821,475 | – | 1.67% | – |
| BLCM | New | BELLICUM PHARMACEUTICALS INC | $7,760,000 | – | 1,051,441 | – | 1.61% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $6,824,000 | – | 1,312,258 | – | 1.41% | – |
| KZR | New | KEZAR LIFE SCIENCES INC | $4,325,000 | – | 250,000 | – | 0.90% | – |
Q4 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,312,258 | – | -3.79% | – |
| SRRA | Exit | SIERRA ONCOLOGY INC | $0 | – | -8,112,121 | – | -4.48% | – |
| IOVA | Exit | IOVANCE BIOTHERAPEUTICS INC | $0 | – | -2,188,331 | – | -6.05% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -1,887,332 | – | -7.06% | – |
| ALPN | Exit | ALPINE IMMUNE SCIENCES INC | $0 | – | -2,199,011 | – | -9.10% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -2,173,593 | – | -9.57% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -2,600,014 | – | -13.98% | – |
| ANAB | Exit | ANAPTYSBIO INC | $0 | – | -3,688,448 | – | -45.97% | – |
Q3 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ALPN | New | ALPINE IMMUNE SCIENCES INC | $25,509,000 | – | 2,199,011 | – | 9.10% | – |
Q2 2017
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| ANAB | New | ANAPTYSBIO INC | $88,265,000 | – | 3,688,448 | – | 45.24% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $26,182,000 | – | 2,600,014 | – | 13.42% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $23,611,000 | – | 1,887,332 | – | 12.10% | – |
| RXDX | New | IGNYTA INC | $22,497,000 | – | 2,173,593 | – | 11.53% | – |
| IOVA | New | IOVANCE BIOTHERAPEUTICS INC | $15,209,000 | – | 2,188,331 | – | 7.80% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $9,842,000 | – | 1,312,258 | – | 5.04% | – |
| SRRA | New | SIERRA ONCOLOGY INC | $9,491,000 | – | 8,112,121 | – | 4.86% | – |
Q4 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| DNAI | Exit | PRONAI THERAPEUTICS INC | $0 | – | -2,186,195 | – | -1.95% | – |
| RXDX | Exit | IGNYTA INC | $0 | – | -950,366 | – | -2.93% | – |
| CDTX | Exit | CIDARA THERAPEUTICS INC | $0 | – | -1,312,258 | – | -7.37% | – |
| LBIO | Exit | LION BIOTECHNOLOGIES INC | $0 | – | -2,087,281 | – | -8.43% | – |
| FOLD | Exit | AMICUS THERAPEUTICS INC | $0 | – | -2,600,014 | – | -9.44% | – |
| COLL | Exit | COLLEGIUM PHARMACEUTICAL INC | $0 | – | -1,887,332 | – | -17.84% | – |
| TBRA | Exit | TOBIRA THERAPEUTICS INC | $0 | – | -2,668,570 | – | -52.04% | – |
Q3 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| FOLD | Sell | AMICUS THERAPEUTICS INC | $19,240,000 | +29.3% | 2,600,014 | -4.6% | 9.44% | -20.5% |
| LBIO | Buy | LION BIOTECHNOLOGIES INC | $17,178,000 | +173.8% | 2,087,281 | +169.4% | 8.43% | +68.4% |
| GKOS | Exit | GLAUKOS CORP | $0 | – | -867,788 | – | -20.18% | – |
Q2 2016
| Value | Shares | ↓ Weighting | ||||||
|---|---|---|---|---|---|---|---|---|
| TBRA | New | TOBIRA THERAPEUTICS INC | $33,517,000 | – | 2,668,570 | – | 26.73% | – |
| GKOS | New | GLAUKOS CORP | $25,305,000 | – | 867,788 | – | 20.18% | – |
| COLL | New | COLLEGIUM PHARMACEUTICAL INC | $22,365,000 | – | 1,887,332 | – | 17.84% | – |
| FOLD | New | AMICUS THERAPEUTICS INC | $14,882,000 | – | 2,725,591 | – | 11.87% | – |
| CDTX | New | CIDARA THERAPEUTICS INC | $13,529,000 | – | 1,312,258 | – | 10.79% | – |
| LBIO | New | LION BIOTECHNOLOGIES INC | $6,275,000 | – | 774,720 | – | 5.00% | – |
| RXDX | New | IGNYTA INC | $5,151,000 | – | 950,366 | – | 4.11% | – |
| DNAI | New | PRONAI THERAPEUTICS INC | $4,351,000 | – | 2,186,195 | – | 3.47% | – |