| Type | Filed | Filer | Subject | Shares Owned | Percent Owned | |
|---|---|---|---|---|---|---|
| SC 13G/A | 2019-02-12 | MORGAN STANLEY | Tekla World Healthcare Fund | 951,883 | 3.1% | EDGAR |
| SC 13G/A | 2018-02-13 | MORGAN STANLEY | Tekla World Healthcare Fund | 1,847,069 | 5.9% | EDGAR |
| SC 13G | 2017-02-13 | MORGAN STANLEY | Tekla World Healthcare Fund | 2,016,168 | 6.5% | EDGAR |