| 2021-01-22 | ORBIMED ADVISORS LLCOrbiMed Capital GP VI LLC | | Sell | Common Stock | -13822463.0 | 0 | $0.0 | U |
| 2021-01-22 | Carson William H. | | Sell | Stock Option (Right to Buy) | -34000.0 | 0 | $0.0 | D |
| 2021-01-22 | Schwartz Kira M. | | Sell | Stock Option (Right to Buy) | -100000.0 | 0 | $0.0 | D |
| 2021-01-22 | Minkow Emily | | Sell | Stock Option (Right to Buy) | -149000.0 | 0 | $0.0 | D |
| 2021-01-22 | Minkow Emily | | Sell | Stock Option (Right to Buy) | -104895.0 | 0 | $0.0 | D |
| 2021-01-22 | Minkow Emily | | Sell | Stock Option (Right to Buy) | -108854.0 | 0 | $0.0 | D |
| 2021-01-22 | Minkow Emily | | Sell | Stock Option (Right to Buy) | -54000.0 | 0 | $0.0 | D |
| 2021-01-22 | Thompson Peter A. | | Sell | Stock Option (Right to Buy) | -17000.0 | 0 | $0.0 | D |
| 2021-01-22 | Kaplan Brett | | Sell | Stock Option (Right to Buy) | -347004.0 | 0 | $0.0 | D |
| 2021-01-22 | Kaplan Brett | | Sell | Stock Option (Right to Buy) | -64565.0 | 0 | $0.0 | D |
| 2021-01-22 | Kaplan Brett | | Sell | Stock Option (Right to Buy) | -95000.0 | 0 | $0.0 | D |
| 2021-01-22 | Dai Yong | | Sell | Stock Option (Right to Buy) | -200172.0 | 0 | $0.0 | D |
| 2021-01-22 | Dai Yong | | Sell | Stock Option (Right to Buy) | -126567.0 | 0 | $0.0 | D |
| 2021-01-22 | Dai Yong | | Sell | Stock Option (Right to Buy) | -43500.0 | 0 | $0.0 | D |
| 2021-01-22 | GORDON CARL L | | Sell | Stock Option (Right to Buy) | -17000.0 | 0 | $0.0 | D |