| Versant Venture Management, LLC | 4,959,769 | $4,668,631 | 5.54% |
|---|
| New Leaf Venture Partners, L.L.C. | 2,497,922 | $2,348,047 | 2.02% |
|---|
| BML Capital Management, LLC | 2,058,767 | $1,937,917 | 1.74% |
|---|
| Lynx1 Capital Management LP | 1,167,343 | $1,098,820 | 0.72% |
|---|
| Acuitas Investments, LLC | 418,173 | $393,626 | 0.23% |
|---|
| Orbimed Advisors | 10,124,576 | $9,530,263 | 0.17% |
|---|
| Frazier Life Sciences Management, L.P. | 1,850,000 | $1,741,405 | 0.10% |
|---|
| TANG CAPITAL MANAGEMENT LLC | 300,000 | $282,390 | 0.04% |
|---|
| Marquette Asset Management, LLC | 86,050 | $80,999 | 0.02% |
|---|
| Annandale Capital, LLC | 54,338 | $51 | 0.02% |
|---|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 389,600 | $366,730 | 0.01% |
|---|
| RBF Capital, LLC | 142,807 | $134,424 | 0.01% |
|---|
| CORNERCAP INVESTMENT COUNSEL INC | 49,767 | $46,846 | 0.01% |
|---|
| Pale Fire Capital SE | 98,662 | $92,871 | 0.01% |
|---|
| Weiss Multi-Strategy Advisers LLC | 367,696 | $346 | 0.01% |
|---|
| FIDUCIARY TRUST CO | 115,000 | $108,250 | 0.00% |
|---|
| ACADIAN ASSET MANAGEMENT LLC | 578,806 | $543 | 0.00% |
|---|
| Renaissance Technologies | 979,095 | $922 | 0.00% |
|---|
| TWO SIGMA INVESTMENTS, LP | 259,854 | $244,601 | 0.00% |
|---|
| TWO SIGMA ADVISERS, LP | 247,700 | $233,160 | 0.00% |
|---|